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      • Performance optimization of flexible a-Si:H solar cells with nanotextured plasmonic substrate by tuning the thickness of oxide spacer layer

        Xiao, Huapeng,Wang, Jun,Huang, Hongtao,Lu, Linfeng,Lin, Qingfeng,Fan, Zhiyong,Chen, Xiaoyuan,Jeong, Chaehwan,Zhu, Xufei,Li, Dongdong Elsevier 2015 Nano energy Vol.11 No.-

        <P><B>Abstract</B></P> <P>Plasmonic thin film solar cells deposited on periodically textured photonic crystal substrates have been extensively studied since the substantially enhanced light absorption. The reduction of parasitic absorption losses in the metal and spacer layers becomes one of the key issues to achieve high efficiency solar cells. Herein, plasmonic amorphous silicon (a-Si:H) flexible thin film solar cells with different thickness of oxide spacer layers are systematically investigated. An increase of the spacer layer thickness leads to an evolution in surface morphology of AZO and final devices. More intriguingly, the increase of spacer layer thickness reduces the absorption in Ag layer while induces more absorption in spacer layer. The highest light absorption in silicon layer is observed as applying 100nm spacer layer, which is further verified by electrical measurements. Our observations demonstrate a versatile and convenient route towards rational design of light harvesting nanostructure for high performance plasmonic solar cells based on a broad range of materials.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Amorphous silicon thin film solar cells are constructed on patterned substrates. </LI> <LI> The devices properties are studied as a function of spacer layer thickness. </LI> <LI> An increase of spacer layer thickness reduces the absorption loss of Ag layer. </LI> <LI> The device with 100nm spacer layer confines more incident light in silicon layer. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • KCI등재

        신흥국 기업 최고경영자의 정치적 연계가 국제인수합병 시 기업가치에 미치는 영향: 중국기업의 해외인수 분석

        LI XIAOYUAN,박용석 한국국제경영학회 2020 國際經營硏究 Vol.31 No.2

        The purpose of this study is to examine the impact of CEO political ties on the value of acquirers from emerging markets after cross-border mergers and acquisitions (CBM&As). No consistent findings on the relationship between CEO political ties and the value of cross-border acquirers exist in prior literature. Since CEO political tie can be a strategic resource for acquirers, while it also can lead conflicts of interest between politicians and shareholders, the impact of CEO political ties on the cross- border acquirer value is unclear. To clarify the effect of CEO political ties on the acquirer value after CBM&As, we apply an institutional perspective to analyse the moderating role of home and host market environment. In this study, 359 Chinese CBM&As between 2008 and 2016 are sampled to test our hypotheses. Test results show that Chinese acquirer CEO with political ties has lower stock returns after the announcement of CBM&A because the rent-seeking behavior from government leads the issue of principal-principal conflict. When the home region is more market-oriented, however, the negative correlation between CEO political ties and firm value is weakened after the announcement of CBM&As because investors would judge the firm behavior independent of political connections. By contrast, when the governance of the target country is more stable, the negative correlation between CEO political ties and firm value is strengthened after the announcement of CBM&As because acquirer CEOs with political ties would face greater obstacles when they do business in such country. The conclusion, implications, and limitations are discussed at the end of the paper. 본 연구는 신흥국 기업이 국제인수합병 시 최고경영자의 정치적 연계가 기업가치에 미치는 영향을 살펴보는데 그 목적을 두고 있다. 기존의 연구들에서는 국제인수합병 시 인수기업 최고경영자의 정치적 연계가 기업가치에 미치는 영향에 관해 혼재된 결과를 제시하였다. 국제인수합병 시 인수기업 최고경영자가 갖고 있는 정치적 연계는 전략적 자원으로서 투자자들에게 긍정적인 시그널을 주지만 정치적 연계로 인해 생기는 정부-기업간 이익충돌 문제는 투자자들에게 부정적인 시그널을 주기 때문이다. 따라서 신흥국 기업 최고경영자의 정치적 연계가 국제인수합병 시 기업가치에 미치는 영향을 보다 명확히 분석하기 위해 본 연구는 제도적 관점을 적용하여 시장 환경의 조절효과를 보여준다. 본 연구는 중국 상장기업이 2008년부터 2016년까지 진행한 국제인수합병 359개 사례를 표본으로 실증연구를 진행하였다. 그 결과 국제인수합병 시 인수기업 최고경영자의 정치적 연계는 정부의 지대추구 행위(rent-seeking behavior)로 인해 정부와 기업 사이 주인간 갈등(principal-principal conflict) 문제를 일으켜 투자자들에게 부정적인 시그널을 주어 기업의 시장가치에 단기적으로 부정적인 영향을 미치는 것으로 나타났다. 하지만 중국 인수기업이 위치한 지역의 시장화 정도가 높을수록 투자자들은 정치적 연계와는 상관없이 기업의 행위를 더욱 객관적으로 판단할 수 있기 때문에 국제인수합병 시 최고경영자의 정치적 연계가 기업가치에 미치는 부정적인 영향은 약화되는 것으로 확인되었다. 반면 피인수기업이 위치한 투자국 거버넌스가 좋을수록 최고경영자의 정치적 연계는 인수기업의 부정적인 이미지를 부각하여 국제인수합병 시 최고경영자의 정치적 연계가 기업가치에 미치는 부정적인 영향은 강화되는 것으로 확인되었다. 본 연구의 결론과 시사점 그리고 한계점에 관해서는 논문 마지막 부분에 정리하였다.

      • KCI등재후보

        Fabricating Composite Cell Sheets for Wound Healing: Cell Sheets Based on the Communication Between BMSCs and HFSCs Facilitate Full-Thickness Cutaneous Wound Healing

        Li Gongjian,Wang Qin,Liu Hao,Yang Zuojun,Wu Yuhan,He Li,Deng Xiaoyuan 한국조직공학과 재생의학회 2024 조직공학과 재생의학 Vol.21 No.3

        Background: Insufficient angiogenesis and the lack of skin appendages are critical challenges in cutaneous wound healing. Stem cell-fabricated cell sheets have become a promising strategy, but cell sheets constructed by a single cell type are inadequate to provide a comprehensive proregenerative microenvironment for wound tissue. Methods: Based on the communication between cells, in this study, bone marrow mesenchymal stem cells (BMSCs) and hair follicle stem cells (HFSCs) were cocultured to fabricate a composite cell sheet (H/M–CS) for the treatment of full-thickness skin wounds in mice. Results: Experiments confirmed that there is cell–cell communication between BMSCs and HFSCs, which enhances the cell proliferation and migration abilities of both cell types. Cell–cell talk also upregulates the gene expression of pro-angiogenic-related cytokines in BMSCs and pro-hair follicle-related cytokines in HFSCs, as well as causing changes in the properties of secreted extracellular matrix components. Conclusions: Therefore, the composite cell sheet is more conducive for cutaneous wound healing and promoting the regeneration of blood vessels and hair follicles. Background: Insufficient angiogenesis and the lack of skin appendages are critical challenges in cutaneous wound healing. Stem cell-fabricated cell sheets have become a promising strategy, but cell sheets constructed by a single cell type are inadequate to provide a comprehensive proregenerative microenvironment for wound tissue. Methods: Based on the communication between cells, in this study, bone marrow mesenchymal stem cells (BMSCs) and hair follicle stem cells (HFSCs) were cocultured to fabricate a composite cell sheet (H/M–CS) for the treatment of full-thickness skin wounds in mice. Results: Experiments confirmed that there is cell–cell communication between BMSCs and HFSCs, which enhances the cell proliferation and migration abilities of both cell types. Cell–cell talk also upregulates the gene expression of pro-angiogenic-related cytokines in BMSCs and pro-hair follicle-related cytokines in HFSCs, as well as causing changes in the properties of secreted extracellular matrix components. Conclusions: Therefore, the composite cell sheet is more conducive for cutaneous wound healing and promoting the regeneration of blood vessels and hair follicles.

      • KCI등재

        Mediatory role of K, Cu and Mo over Ru/SiO2 catalysts for glycerol hydrogenolysis

        Xiaoyuan Liao,Kewen Li,Xiaomin Xiang,Sheng-Guang Wang,Xichun She,Yulei Zhu,Yongwang Li 한국공업화학회 2012 Journal of Industrial and Engineering Chemistry Vol.18 No.2

        SiO2 supported ruthenium catalysts with and without modifiers were prepared, characterized and tested for glycerol hydrogenation. Addition of K, Cu and Mo affects the reducibility and acidity of the Ru/SiO2catalyst. Characterization data shows that Cu and Mo-modified Ru/SiO2 have stronger acidity. On the contrary, K element on a passive effect on the acidity of Ru based catalyst had been observed. A comparison with the pure Ru/SiO2 indicates the Cu-promoted specimen has better selective to the desired products, acetol, 1,2-propanediol and ethyl glycol, although the reactivity is slightly lower.

      • KCI우수등재
      • KCI등재

        Fatty Acid Biosynthesis in Eukaryotic Photosynthetic Microalgae: Identification of a Microsomal Delta 12 Desaturase in Chlamydomonas reinhardtii

        Xiaoyuan Chi,Xiaowen Zhang,Xiangyu Guan,Ling Ding,Youxun Li,Mingqing Wang,Hanzhi Lin,Song Qin 한국미생물학회 2008 The journal of microbiology Vol.46 No.2

        Polyunsaturated fatty acids (PUFAs) are important components of infant and adult nutrition because they serve as structural elements of cell membranes. Fatty acid desaturases are responsible for the insertion of double bonds into pre-formed fatty acid chains in reactions that require oxygen and reducing equivalents. In this study, the genome-wide characterization of the fatty acid desaturases from seven eukaryotic photosynthetic microalgae was undertaken according to the conserved histidine-rich motifs and phylogenetic profiles. Analysis of these genomes provided insight into the origin and evolution of the pathway of fatty acid biosynthesis in eukaryotic plants. In addition, the candidate enzyme from Chlamydomonas reinhardtii with the highest similarity to the microsomal Δ12 desaturase of Chlorella vulgaris was isolated, and its function was verified by heterologous expression in yeast (Saccharomyces cerevisiae).

      • KCI등재

        Hypoxia-induced LncRNA DACT3-AS1 upregulates PKM2 to promote metastasis in hepatocellular carcinoma through the HDAC2/FOXA3 pathway

        Wang Liyan,Li Bin,Bo Xiaotong,Yi Xiaoyuan,Xiao Xuhua,Zheng Qinghua 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-

        Growing evidence has revealed that hypoxia is involved in multiple stages of cancer development. However, there are limited reports on the effects of long noncoding RNAs (lncRNAs) on hepatocellular carcinoma (HCC) progression under hypoxia. The main purposes of this study were to analyze the effect of the novel lncRNA DACT3-AS1 on metastasis in HCC and to elucidate the related molecular mechanism. Bioinformatics tools were employed. RT–qPCR or western blot assays were conducted to detect RNA or protein expression. Clinical samples and in vivo assays were utilized to reveal the role of DACT3-AS1 in HCC. Other mechanism and functional analyses were specifically designed and performed as well. Based on the collected data, this study revealed that HIF-1α transcriptionally activates DACT3-AS1 expression under hypoxia. DACT3-AS1 was verified to promote metastasis in HCC. Mechanistically, DACT3-AS1 promotes the interaction between HDAC2 and FOXA3 to stimulate FOXA3 deacetylation, which consequently downregulates the FOXA3 protein. Furthermore, FOXA3 serves as a transcription factor that can bind to the PKM2 promoter region, thus hindering PKM2 expression. To summarize, this study uncovered that HIF-1α-induced DACT3-AS1 promotes metastasis in HCC and can upregulate PKM2 via the HDAC2/FOXA3 pathway in HCC cells.

      • KCI등재

        Adaptive robust control of active magnetic bearings rigid rotor systems

        Yuhao Xu,Xiaoyuan Wang,Mingxin Liu,Na Li,Tian Yu 전력전자학회 2023 JOURNAL OF POWER ELECTRONICS Vol.23 No.6

        Aiming at the problems of diffi cult decoupling, complex controller models, and poor disturbance rejection capability caused by the inherent nonlinear and strong coupling characteristics of the active magnetic bearing (AMB), an adaptive H-infinity robust control (AHRC) method is proposed in the AMBs-rigid rotor system. The proposed method combines the active disturbance rejection control (ADRC) with the robust control to achieve stable operation of the AMBs-rigid rotor system under high-speed conditions. First, a four-degree-of-freedom (4-DOF) AMBs-rigid rotor model was established and transformed into a one-degree-of-freedom (1-DOF) model for the design of the robust controller, which weakens the coupling effect between each of the degrees of freedom (DOF). Then the multi-objective non-dominated sorting genetic algorithm II (NSGA-II) was used to fi nd the relative optimal weighting function value of the H-infinite robust control (HRC), which solved the difficulties in the design of the robust controller for known controlled system models. In addition, by combining the optimized H-infi nity robust controller with the original error feedback control rate in the ADRC, the proposed AHRC retains the strong robustness of the HRC and the decoupling capability of the ADRC, which improves the tracking performance and anti-disturbance performance of the controlled system. Simulation and experimental results verify the effectiveness of the proposed method.

      • KCI등재
      • Intracellular Mechanistic Understanding of 2D MoS<sub>2</sub> Nanosheets for Anti-Exocytosis-Enhanced Synergistic Cancer Therapy

        Zhu, Xianbing,Ji, Xiaoyuan,Kong, Na,Chen, Yunhan,Mahmoudi, Morteza,Xu, Xiaoding,Ding, Li,Tao, Wei,Cai, Ting,Li, Yujing,Gan, Tian,Barrett, Austin,Bharwani, Zameer,Chen, Hongbo,Farokhzad, Omid C. American Chemical Society 2018 ACS NANO Vol.12 No.3

        <P>Emerging two-dimensional (2D) nanomaterials, such as transition-metal dichalcogenide (TMD) nanosheets (NSs), have shown tremendous potential for use in a wide variety of fields including cancer nanomedicine. The interaction of nanomaterials with biosystems is of critical importance for their safe and efficient application. However, a cellular-level understanding of the nano-bio interactions of these emerging 2D nanomaterials (<I>i</I>.<I>e</I>., intracellular mechanisms) remains elusive. Here we chose molybdenum disulfide (MoS<SUB>2</SUB>) NSs as representative 2D nanomaterials to gain a better understanding of their intracellular mechanisms of action in cancer cells, which play a significant role in both their fate and efficacy. MoS<SUB>2</SUB> NSs were found to be internalized through three pathways: clathrin → early endosomes → lysosomes, caveolae → early endosomes → lysosomes, and macropinocytosis → late endosomes → lysosomes. We also observed autophagy-mediated accumulation in the lysosomes and exocytosis-induced efflux of MoS<SUB>2</SUB> NSs. Based on these findings, we developed a strategy to achieve effective and synergistic <I>in vivo</I> cancer therapy with MoS<SUB>2</SUB> NSs loaded with low doses of drug through inhibiting exocytosis pathway-induced loss. To the best of our knowledge, this is the first systematic experimental report on the nano-bio interaction of 2D nanomaterials in cells and their application for anti-exocytosis-enhanced synergistic cancer therapy.</P> [FIG OMISSION]</BR>

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