지안 로렌조 베르니니의 건축공간의 해석에 관한 연구 : 건축에 적용된 조각의 도상해석학적 분석을 중심으로 Focused on the Iconological Analysis of Sculptures added to Architecture

남경훈,이강업,진경돈 대한건축학회 2003 대한건축학회논문집 Vol.19 No.2

This study considered the characteristics of Gian Lorenzo Bernini's inclusive architecture by means of the iconological interpretation of the relationship between his architecture and sculpture. There have been many studies of Bernini's sculpture and architecture apart, and it is the fact that especially studies of his architecture have remained at stylistic one. However it is not so much difficult to find the ensemble made by symbolic relationship between architecture and sculpture in Bernini's works. Therefore this study introduced Erwin Panofsky's Iconology methodologically to analyze his architectural works and to show that they could be interpreted from sculpture added to architecture. According to iconological analyses about Bernini's Sant' Andre al Quirinale and Scala Regia, followings were investigated. Firstly, The sculptures added to each architectural space are not simple baroque decorations but project symbolic meanings such as the religious symbolism, the historicity of site, and the needs of the time. Secondly, each architecture and sculpture organize spatial characteristics in harmony by means of the projected symbolic meaning. Thirdly, the motive which make him add many sculptures to architectural space are neo-platonism, city planning of Baroque, and political reasons which reinforce the papacy.

침습성 아스페르길수스증 진단을 위항 갈락토만난 항원검사의 유용성 평가

송경호,이신원,장희창,전재현,박완범,박경운,박상원,오명돈,최강원 대한감염학회 2009 감염과 화학요법 Vol.41 No.2

Background : Invasive aspergillosis (IA) is an important cause of morbidity and mortality among immunocompromised patients. However, 1A is difficult to diagnose, especially in the aforementioned patient group. Recently, galactomannan assay (GMA) using enzyme immunoassay has been introduced in Korea. We evaluated its diagnostic usefulness in the diagnosis of 1A and we analyzed the results according to the underlying diseases. Materials and Methods : All patients who underwent GMA during the period from October 2007 to June 2008 were evaluated retrospectively. According to the criteria of European Organization for Research and Treatment of Cancer/Mycoses Study Group, IA was classified into four clinical categories: proven', probable', possible', and 'non' IA. Patients with 'proven' and 'probable' IA were used as the reference standards for IA. GMA was performed using Platelia Aspergillus EIA (Bio-Rad, Hercules, CA, USA). Optical density index ≥0.5 was considered positive. Results : Of the 144 patients who underwent GMA, two patients were classificed as proven' IA and sixteen patients were probable' 1A. Overall sensitivity, specificity, positive predictive value, and negative predictive value of the assay were 50% (95% confidence interval [C195), 26-74%), 88% (C195, 81-93%), 38% (CI95, 19-59%), and 93% (CI95, 86-97%), respectively. Among the 99 patients with underlying hematologic diseases, GMA showed 67% (C195, 35-90%) sensitivity and 89% (C195, 80-94%) specificity, whereas in 45 patients with underlying diseases other than hematologic diseases, sensitivity and specificity of the assay were 17% (CI95, 0-64%) and 87% (CI95, 73-96%), respectively. Conclusions : GMA showed high specificity, irrespective of the patient population. However, sensitivity of GMA was low and the assay was less sensitive in patients with underlying diseases other than hematologic diseases than in patients with hematologic diseases.

최서해와 기록의 소설화

이경돈 반교어문학회 2003 泮橋語文硏究 Vol.15 No.-

최서해는 1920년대 신경향파 소설가로 널리 알려져 있다. 실제 임화가 이른바, 신경향파의 두 흐름인 최서해적 경향과 박영희적 경향 중 한 축을 이루고 있음은 그 사실을 잘 말해준다. 1920년대 소설에 근대소설로서의 완연한 육체를 전제했을 때, 이러한 판단은 정당하다고 할 수 있다. 그러나 1920년대 소설은 생성되기 시작했고, 근대소설로서의 육체를 형성해가고 있었다. 개연성 있는 허구로서의 그럴듯함을 구축해가던 시기였다는 뜻이다. 최서해의 작품들은 허구적 실감을 작도하기 위해 실사(實寫)의 방법이 차용되었음을 확인시켜주는 가장 뚜렷한 증좌라고 할 수 있다. 그의 출세작인 「탈출기」 는 소설이기에 앞서 감상문이었고, 개작의 결과로 산출된 「기아와 살육」도 애초 경험 기록의 산물이었다. 최서해의 작품 외적 언급과 개작 과정을 중심으로 한 특징들을 살펴볼 때, 이러한 창작 방법에 기대고 있는 작품은 적지 않다. 지금까지 최서해를 해명하며 애용되었던 체험소설이라는 평가는 한편으로 최서해의 소설이 체험에 기댄 바 적지 않음을 말해주는 것이지만, 다른 한편으로는 소설의 방법이 기록의 방법과는 별개의 것임을 전제하고 있다는 점에서 체험적 요소가 많은 소설 정도의 의미를 형성해왔다. 그러나 이 시기의 소설이 여전히 소설의 육체를 성립시키는 과정에 있었음과 함께, 김동인, 현진건, 염상섭 등의 작가 역시 체험을 기록하는 방법을 통해 신빙성 있는 서술자를 중심으로 한 소설의 실감을 구축했다는 점을 고려한다면 「탈출기」를 비롯한 최서해의 소설은 체험의 비중이 큰 소설이 아니라 경험 기록에 의해 소설다운 소설이 산출되는 과정을 보여주는 것이라 할 수 있다. 특히 경험을 그대로 기록하되 서사와 묘사의 확장을 통해 소설과 흡사한 모습을 띤 기록서사의 존재는 최서해의 창작 방법이 다만 소설의 그것에 국한되지 않는 성질을 띠고 있음을 알려주는 증좌라 할 수 있다. 단적으로 최서해의 소설은 기록정신에 기반해 실사(實寫)의 방법으로 소설을 만들어낸 경우인 것이다. 실사의 방법에 의한 소설 창작의 경향은, 다만 최서해 뿐 아니라 ??조선문단??을 통해 등장하는 채만식을 비롯한 신진작가들에게서 흔히 발견되는 것이며, ??조선문단??이 지향한 문학의 대중화와 맞물려 이후 소설의 범주에 적지 않은 영향을 행사하게 되었다. 무리를 감수한다면, 우리 근대소설이 요구해온 완강한 리얼리티의 근저에는 기록의 소설화, 실사의 방법이라는 소설 외적 방법론이 자리를 잡고 있다고 할 수도 있지 않을까 생각된다. We know that Choi soe-hae was a new tendency school writer or experimental novel writer. His short novel's feature is that he wrote realistic experience in his novels, and thus is recognized as a early stage of realism. So it is estimated the new tendency school, that is the pre-stage of proletariat-literature. But basically his writing method is not that of the novel. It refused the fictionality of a major proposition in the novel. But we can not say it is not the novel because his short novels have been recognized as a novel for a long time. For by 1920s novel is the process of the formation in contents and forms. Also Chae man-sik, Han soel-ya ascended the platform in mid 1920s. For their early works were identical with his writing method, we should exclude the possibility that his writing method was the personal deviation. So his writing method is different from anti-novelistic intention or borrowed writing method. That is different meaning from the transplanted idea of novel. That is to say it is the novel in conventional meaning. To expand it, it was the origin of maintaining strict realities in Korean novels.

Shield Disk 상의 Ag-Cu 공정계 합금 도금기술 개발

윤경도,차동관,심기종,민봉기,최순돈,이상기 嶺南大學校 工業技術硏究所 2003 工業技術硏究所論文集 Vol.31 No.1

The composition and the microstructure of the Ag-Cu alloy electrodeposits electroplated in Succinimide bath were investigated varying the electrolysis conditions such as bath composition, current density and additive agents etc. The cathode overpotential increased with the increase of Succinimide concentration and current density ratio in the bath. The Ag content of the alloy deposits decreased with the increase of current density and pH and temperature in the bath. The optimum condition for 78wt.%Ag-22wt.%Cu code position alloy is an follows : pH10(adjusted by NH_4OH), 0.03M AgNO_3, 0.27M Cu(NO_3)_2 3H_2O, 0.5M Succinimide in bath and 3.5A/dm^2∼5.5A/dm^2 current density.

악교정 수술에서 모의 조종된 3차원 전산화 단층촬영상의 응용

김형돈,이경상,유선국,박창서 大韓口腔顎顔面 放射線學會 1998 Imaging Science in Dentistry Vol.28 No.2

In orthodontics and orthognathic surgery, cephalogram has been routine practice in diagnosis and treatment evaluation of craniofacial deformity. But its inherent distortion of actual length and angles during projecting three dimensional object to two dimensional plane might cause errors in quantitative analysis of shape and size. Therefore, it is desirable that three dimensional object is diagnosed and evaluated three dimensionally and three dimensional CT image is best for three dimensional analysis. Development of clinic necessitates evaluation of result of treatment and comparison before and after surgery. It is desirable that patient that was diagnosed and planned by three dimensional computed tomography before surgery is evaluated by three dimensional computed tomography after surgery, too. But Because there is no standardized normal values in three dimension now and three dimensional Computed Tomography needs expensive equipments and because of its expenses and amount of exposure to radiation, limitations still remain to be solved in its application to routine practice. If postoperative three dimensional image is constructed by pre and postoperative lateral and postero-anterior cephalograms and preoperative three dimensional computed tomogram, pre and postoperative image will be compared and evaluated three dimensionally without three dimensional computed tomography after surgery and that will contribute to standardize normal values in three dimension. This study introduced new method that computer-simulated three dimensional image was constructed by preoperative three dimensional computed tomogram and pre and postoperative lateral and postero-anterior cephalograms, and for validation of new method, in four cases of dry skull that position of mandible was displaced and four patients of orthognathic surgery, computer-simulated three dimensional image and actual postoperative three dimensional image were compared. The results were as follows. 1. In four cases of dry skull that position of mandible was displaced, range of displacement between computer-simulated three dimensional images and actual postoperative three dimensional images in co-ordinates values was from -1.8 mm to 1.8 mm and 94% in displacement of all co-ordinates values was from -1.0 mm to 1.0 mm and no significant difference between computer-simulated three dimensional images and actual postoperative three dimensional images was noticed(p>0.05). 2. In four cases of orthognathic surgery patients, range of displacement between computer-simulated three dimensional images and actual postoperative three dimensional images in coordinates values was from -6.7 mm to 7.7 mm and 90% in displacement of all co-ordinates values was from -4.0 to 4.0 mm and no significant difference between computer-simulated three dimensional images and actual postoperative three dimensional images was noticed(p>0.05). Conclusively, computer-simulated three dimensional image was constructed by preoperative three dimensional computed tomogram and pre and postoperative lateral and postero-anterior cephalograms. Therefore, potentiality that can construct postoperative three dimensional image without three dimensional computed tomography after surgery was presented.

반복적인 부비동염으로 내원한 Good 증후군 1예

송경호,김계형,김충종,박경운,전상훈,김홍빈,김남중,오명돈,최강원 대한감염학회 2007 감염과 화학요법 Vol.39 No.5

Good 증후군은 흉선종과 면역결핍이 동반되는 질환으로, B세포의 감소로 인한 범저감마글로불린혈증과 CD4^(+)T세포의 감소로 인한 세포성 면역저하가 동시에 나타나는 것을 특징으로 한다. 본 증례는 18개월 전부터 발생한 반복적인 부비동염을 주소로 내원한 43세 남자 환자로, 내원 1년 전 흉선종절제수술을 시행받았으며, 면역학적 검사상 범저감마글로불린혈증과 T세포의 감소 등의 이상 소견이 발견되었다. 정주 면역글로불린과 경험적 항생제(amoxicillin/clavulanic acid) 사용 후 부비동염이 호전되었으며, 예방접종과 정기적인 면역글로불린 투여 후 특이 합병증없이 경과 관찰 중이다. Good's syndrome is the association of thymoma with immunodeficiency, characterized by hypogammaglobulinemia, B-cell lymphopenia and variably defects in cellular immunity with CD4^(+) T-cell lymphopenia and an inverted CD4^(+):CD8^(+) T-cell ratio. We report a 43-year-old male patient who presented with a 18-month history of productive cough and postnasal drip. One year ago, he underwent the operation for resection of a thymoma. Despite of appropriate management, sinusitis relapsed multiple times. He was found to have hypogammaglobulinemia with nearly absent B cells(4/μL). The CD4^(+) T-cell count was 554/μL with an inverted CD4^(+):CD8^(+) T-cell ratio of 0.6. His symptoms and signs improved with antibiotic treatment and monthly administration of intravenous immunoglobulin (IVIG, 400 mg/kg).

조갑진균증에서 Ciclopirox Nail Lacquer의 치료효과

박경찬,김정애,방형돈,조광현,윤재일,김병수 대한감염학회 1995 감염 Vol.27 No.3

배경 및 목적:조갑진균증의 치료에 있어 국소용 항진균제는 조갑판을 통과하지 못하기 때문에 치료율이 낮은 것으로 알려졌으나 최근 조갑판을 통과하여 조상에서도 높은 치료농도를 유지할 수 있는 국소용 항진균제인 ciclopirox nail lacquer가 개발되었다. 이에 본 저자들은 8% ciclopirox nail lacquer 단독 도포의 조갑진균증에서의 치료 효과와 안전성을 알아 보기 위한 연구를 수행하였다. 방법:표적 조갑판의 감염된 면적의 비율이 50%이하인 경증의 조갑진균증 환자 27명을 평가 대상으로 하였으며 8% ciclopirox nail lacquer 1일 1회 도포요법으로 6개월간 치료하였다. 매 방문시마다 감염면적 비율을 기록하였고 치료 전과 치료 후 진균 검사를 시행하였다. 결과: 1)표적조갑판의 감염 면적이 치료 전 평균 28.9%에서 치료 종료시 4.7%로 통계적으로 유의하게 감소하였다(p<0.001). 2)KOH 직접 도말 검사와 진균 배양 검사에서 모두 음성인 진균학적 완치율은 치료 종료시 77.8%였다. 3)부작용으로는 3명(11.1%)에서 일시적 작열감, 조갑 감입 등을 호소하였다. 결론:경증의 조갑진균증 치료에 있어 8% ciclopirox nail lacquer는 비교적 좋은 치료 효과를 보이며 부작용이 적은 약제로 생각된다. Background: Topical antifungal agents have been ineffective in the treatment of onychomycosis because they could not reach the infected nail bed. 8% ciclopirox nail lacquer is a new topical antimycotic which is characterized by excellent penetration into the nail plate. We performed a study to assess the therapeutic efficacy and safety of 8% ciclopirox nail lacquer in the treatment of onychomycosis. Methods: We assessed 27 onychomycotic patients whose affected area of target nail plate was not more than 50%. The patients were instructed to apply 8% ciclopirox nail lacquer once daily and evaluated monthly for 6 months. Mycological examinations were done before and after the treatment. Overall efficacy, tolerability, cosmetic acceptance and adverse effects were assessed at the end of 6 months' treatment. Results: The mean percentage of affected area decreased from 28.9% to 4.7%. Mycological cure rate was 77.8% at the end of the treatment. Overall efficacy assessed by physician and patients were similar and evaluated as complete cure in 48% and 44%, respectively. Tolerability and cosmetic acceptance were excellent or good in most of the patients. No systemic adverse effects were found, but 3 patients complained of mild prickling sensation or ingrowing toe nail. Conclusions: These data suggest that 8% ciclopirox nail lacquer is safe and effective in the treatment of mild onychomycosis.

초등교사의 환경관련 수업에 대한 교사전문성

손연아,김경란,민병미,최돈형 한국초등과학교육학회 2005 초등과학교육 Vol.24 No.2

The purpose of this study was to analyze the professionalism of elementary school teachers and to draw out factors which elementary teachers should try to improve their professionalism for environmental education. For the study, both Quantitative analysis and qualitative methodologies were applied: First, randomly selected 483 elementary teachers from Seoul and Gyeonggi self responded to 5 evaluation areas by Hungerford et al. (1994) to evaluate their environmental education professionalism through the use of five point Likert scale. Second, 2 elementary teachers' environmental classes were observed for the purpose of analyzing strengths and weaknesses in classroom instruction, and then the results of self-evaluation on environmental education professionalism and teacher professionalism as shown in the classes were compared. It was found that 483 elementary teachers including 2 teachers for analyzing classroom instruction who performed a self-evaluation gave themselves mid-scores on the Hungerford et al.'s 5 evaluation areas. However, the result of self-evaluation did not correspond with the result of actual class observation and teacher interview. That is, the actual environmental classes conducted by 2 teachers did not seemed to reflect the evaluation areas which were the foundation of the study: the conceptual awareness, the investigation & evaluation, environmental action skills, and educational application. The results of this study can be used as the basis reference to develop teaching-learning program and in-service programs for professional development of teachers for successful application of environmental education in elementary school classes.

직업성 청력손실과 이에 미치는 제인자들의 영향에 관한 조사 연구

이용환,김돈균 부산의대 1991 부산의대잡지 - 부산대학교 의과대학 Vol.31 No.2

일렬 자가조혈모세포이식을 받은 다발성 골수종 환자에서 발생한 뇌 톡소포자충증 1례

김계형,송경호,전재현,박완범,박상원,김홍빈,김남중,김인호,오명돈 대한감염학회 2010 감염과 화학요법 Vol.42 No.3

Toxoplasmosis is a rare but fatal complication in hematopoietic stem cell transplant recipients, usually associated with allogeneic hematopoietic stem cell transplantation (HSCT). We report a case of cerebral toxoplasmosis in a patient with multiple myeloma, following tandem autologous stem cell transplantation. A 55-year-old Korean male presented with weakness in both legs that had progressed to both arms. A magnetic resonance imaging scan of the brain revealed multiple, variablesized ring-enhancing lesions with surrounding edema in the cerebral hemispheres and brain stem. Stereotactic biopsy revealed bradyzoites of Toxoplasma gondii in the brain tissue. The patient received trimethoprim-sulfamethoxazole, followed by pyrimethamine and sulfadiazine, accompanying treatment for progressive multiple myeloma. Cerebral toxoplasmosis should be considered as one of the differential diagnoses in patients with neurologic signs following autologous HSCT.