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방형돈(Hyeong Don Bang),정진호(Jin Ho Chung),조광현(Kwang Hyun Cho),윤재일(Jai Il Youn) 대한피부과학회 1995 대한피부과학회지 Vol.33 No.1
The allopurinol hypersensicivity syndrome is a rare, but life thereaning immunologic reaction of allopurinol therapy, characterized by multiple abnormalities such as fever, rash, decreased renal function, hepatocellular injury, leukocytosis, and eosinophila. It may require prolonged hospitalization and occasionally involves residual morbidity. Three patients developed erythematous skin eruption three to five weeks after beginning therapy with allopurinol. The clinical, laboratory, and histologic findings of these patients were compatible with a allopurinol hyperensitivity syndrome. (Kor J Dermatol 1995; 33(1): 130-134)
방형돈 ( Hyeong Don Bang ),안필수 ( Phil Soo Ahn ),김규한 ( Kyu Han Kim ),박경찬 ( Kyoung Chan Park ),권준수 ( Jun Soo Kwon ) 대한피부과학회 1996 대한피부과학회지 Vol.34 No.3
Background: Atopic dermatitis will persist into adult life and chronic severe atopic dermatitis may cause significant interference in social interaction. Despite the controversy concerning the existence of specific personality exhibited by patients with atopic dermatitis, psychological and social factors have long been considered important factors that have influence on the course of the disease. Objective : The purpose of this study was to investigate the charateristics of the personalities of adult patients with atopic dermatitis and their relationship to psychological factors and clinical characteristics. Methods : Eysenck Personahty Questionnaire(EPQ) was carried out on 54 adult patients with atopic dermatitis. Using the EPQ scores, a cluster analysis was done to identify the subgroup of psychologically disabled patients. The psychological and social aspects of the identified patients were then investigated using a designed questionnaire. Results : 1. A cluster analysis identified two patient subgroups. Psychoticism(P), extroversion-introversion(E), and neuroticism(N) scores were significantly different between the subgroups. The neuroticism scores were above the upper limit of the normal range in the higher EPQ scored subgroups. However, the total clinical severity score which was evaluated in 25 patients showed no significant difference between these subgroups. 2. The higher psychoticism, extroversion-introversion, and neuroticism scored patients tended to express severe disability due to atopic dermatitis and a high level of stress which was evaluated by the designed questionnaire. Conclusion : Eysenck personality questionnaire can be helpful in identifying a subgroup of patients who may need psychiatric intervention. (Kor J Dermatol 1996;34(3): 359-365)
전진곤,방형돈,김광호,김광중 대한피부과학회 2003 大韓皮膚科學會誌 Vol.41 No.5
Male breast cancer is a rare disease, accounting for approximately 1% of all breast cancer. We report a case of cutaneous, osteolytic, pulmonary, and hepatic metastases of male breast cancer in a 40-year-old male who presented 4 × 2.5 ㎝ erythematous plaque with ulceration and bloody discharge on the areolar area of the left anterior chest. The histopathologic findings of the lesion showed nests and strands of invasive carcinoma forming ductlike structures and cellular arrangement in single-row line, referred to as Indian filing, between collagen bundles. The tumor cell showed positive reaction for estrogen receptor, but negative reaction for progesterone receptor. He was treated with tamoxifen, 5-fluouracil, adriamycin, and cyclophosphamide. Six months after initiation of the treatment, skin lesion was improved. Also, number and size of the metastatic cancer nodules decreased in the computer tomographic imaging. (Korean J Dermatol 2003;41(5) : 660~663)
전현진,방형돈,김광호,김광중 대한피부과학회 2003 大韓皮膚科學會誌 Vol.41 No.4
Ramsay Hunt syndrome or herpes zoster oticus is a viral disease associated with otalgia, vesicuTar eruption, facial paralysis, hearing disturbance, tinnitus, vertigo and other symptoms. Rarely it can be associated with involvement of Ⅳ, Ⅴ, Ⅸ, Ⅹ, XI, XII cranial nerves, cervical plexus, and diffuse encephalitis. We report a case of Ramsay Hunt syndrome with vocal cord paralysis which developed prior to facial nerve paralysis. (Korean J Dermatol 2003;41(4) : 507~509)
김성식,방형돈,김광중,김종민,손진희,김광호,최준용 대한피부과학회 2002 大韓皮膚科學會誌 Vol.40 No.6
Adenoid cystic carcinoma of the breast is a rare histologic type of breast cancer. Prognosis is favorable with rare recurrence or metastasis. We report a case of metastatic adenoid cystic carcinoma of the breast in a 50-year-old woman who presented with a 0.8\0.9/0.5cm-sized dome shaped pink colored smooth surfaced partially eroded nodule on the scalp for 1 month. A skin biopsy revealed mainly solid malignant cell nests in the upper dermis, but in the lower dermis, tumor cell showed cylindromatous and adenoid pattern consistent with metastatic adenoid cystic carcinoma of the breast.
안필수,방형돈,정진호,김규한,박경찬,윤재일 대한천식알레르기학회 1996 천식 및 알레르기 Vol.16 No.3
Recent studies have suggested decreased interferon gamma(IFN r) but high interleukin 4 (IL - 4) production in patients with atopic dermatitis(AD). Based on the fact that the relative activities of IL 4 and IFN r seem to regulate the amplitude of IgE response, we tried rIFN r in the treatment of severe AD. Patients with severe AD(n=ll) were treated with recombinant IFN y 2.0 million IU/ml by subcutaneous injection for 12 weeks. During the study basic local therapy with low potency corticosteroid or emollient ointment and oral medication of antihistamine were allowed. Ten patients completed the treatment course and one patient discontinued the treatment before completion due to high fever. Seven patients(64% ) showed marked clinical improvement after 12 weeks of systemic IFN r therapy. Headache or mild fever were observed in 6 patients but they were improved by acetaminophen. Elevated SGOT and SGPT was observed in one patient but improved by temporary discontinuation of rIFN r. Our results suggested that rIFN r treatment may be one of the effective therapeutic regimens in patients with severe AD.