위암환자의 복강내에 투여한 Mitomycin C-Carbon Particle의 Mitomycin 용출에 관한 연구

노승무,조영훈,정경수,오정연,김진향,양준묵,강대영,송규상,조준식,최선웅,이진호,민병무,김용백,김창식,박근성,인현빈,정현용,김학용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherpy seems a logical choice for cancer chemotherapy. The Mitomycin C(MMC) adsorbed by the activated charcoal particles(CH) is relatively released when the drug concentration surrounding the carbon particles becomes low in the peritoneum of the peritoneal cavity. For the intraperitoneal chemotherapy on the advanced gastric adenocarcnoma, mitomycin C adsorbed on activated carbon particles was administered in the peritoneal cavity just before abdominal wall closure. The closed drainage tubes were inserted in the peritoneal cavity and clamped for tuo hours after completion of operation. MMC concentrations were serially measured in peritoneal fluid, plasma and urine at 2hour, 48 hour, 72 hour and 168 hour following its administration in order to study the efficacy of the MMC-CH as a drug delivery system. There were minimal toxicities in born marrow, liver, and gastrointestinal system after intraperitoneal MMC-CH administration. The data of this study suggested that MMC-CH may have a somewhat more beneficial effect than surgery alone when administered in optimal dose and schedules, but the MMC concentration of the peritoneal fluid was not sufficient to eradicate remnant cancer cells, and effective duration of maintenance was only below 24 hours in the peritoneal fluid and plasma.

유전 알고리즘을 이용한 거리 정보의 추출

김용석,도경훈 東西大學校 1997 동서논문집 Vol.3 No.1

In this paper, a genetic algorithm-based optimization technique for stereo matching is proposed. Stereo matching is the essential process to recover three-dimensional structure of objects. The geometrical difference of left and right images called as disparity is constructed as two-dimensional chromosomes with fitness values inversely proportional to their costs. The cost function is composed of the intensity-difference between two images and smoothness of disparity. The crossover and mutation operators in the two-dimensional chromosomes is described. The operations are affected by the disparities of neighbor pixels. The knowledge-augmented operators is shown to result in rapid convergence and stable result. The genetic algorithm for stereo matching is tested on synthetic and natural images. Experimental results for various images show that the proposed algorithm has good performance even if the image has the unfavorable conditions.

중소도시 하수관거의 침입수량 및 수질오염 원단위 산정

김옥형,박승기,정재훈,임경호 公州大學校 工學硏究院 生産技術硏究所 2004 論文集 Vol.12 No.-

The volume of wastewater in combined sewers in study areas usually exceeds capacities of the sewer system or the treatment plant during storms. For this reason, combined sewer systems are designed to overflow occasionally and discharge excess waste water. The 6 monitoring sites were selected from two small cities near the Hongsung prefecture during over a rainy season. Monitoring was performed by collecting grab samples and by measuring the rainfall and flow rates during dry and wet seasons. Generally the flow rate of wastewater in combined sewers was rapidly decreased after 23:00 PM and gradually increased from 06:30 AM in all sites during the dry season. Due to monitoring and statistical analysis, the groundwater contributes on sewage volume increase (average 3.4-25.4% more) during experimental periods. Therefore, this research is focus on the investigation of the effects of stormwater and groundwater to combined sewer systems.

다발성 흉추간판탈출증 : 2례 증례보고 Report of 2 Cases

김상진,성경훈,강재규,도종웅 대한신경외과학회 1990 Journal of Korean neurosurgical society Vol.19 No.1

The authors describe 2 cases of multiple thoracic disc herniations in the level of T5∼6, T6∼7, T7∼8 and T8∼9, T9∼10, T10∼11. Thoracic disc herniation is rare and occurs in less than 4% of all disc diseases. Moreover, multiple thoracic disc herniation is very rare and only 7 cases were reported in the literatures, which occured at two levels in 6 cases and five levels in one case. The lesions were determined by thoracic CT myelogram and MRI study. A microsurgical posterolateral approach made them curative. Surgical instruments such as downbite currette and surgical microscope were essential for successful treatment.

흉추간판 탈출증의 미세현미경적 후측방 접근법

김상진,성경훈,박순필,도종웅 대한신경외과학회 1988 Journal of Korean neurosurgical society Vol.17 No.6

The authors describe the case of a man who presented with T2-T3 disc herniation. The lesion was successfully identified by computed tomography with iopamidol myelogram and other radiological examinations. A posterolateral approach was tried and made successful result by the aids of microsurgcial divices.

열처리 시간에 따른 니켈전기도금층의 집합조직 변화

김인수,홍상철,조경식,오명훈,김인기 金烏工科大學校 1999 論文集 Vol.20 No.-

Ni electrodeposits having preferred orientation can be obtained by various electrolysis conditions. Ni electrodeposits were annealed at 580℃ with various time. Ni electrodeposits having (100) texture did not change, (110) texture changed to various texture after recrystallization

칼만증후군(Kallmann's Syndrome) 1례

김용성,백승훈,유경훈,구기선,형근영,김경년,조정구 圓光大學校 醫科學硏究所 1997 圓光醫科學 Vol.13 No.1-2

Kallmann's syndrome is the most common form of isolated gonadotropin deficiency, characterized by hypogonadotropic hypogonadism due to GnRH deficiency, delayed puberty and smelling difficulty. It occurs sporadic or familial pattern, and the mode of inheritence has not been fully documented. The defect in patient of Kallmann's syndrome occurs at suprapituitary level involving mechanism that regulate GnRH synthesis or release, so this syndrome classified as a secondary hypogonadotropic hypogonadism. The gonadotropin or pulsatile GnRH administration enable successful stimulation of spermatogenesis and fertility. We have experienced 1 patient with Kallmann's syndrome and presented with the review of the literature.

용접판재의 피로강도에 미치는 잔류응력 평가

차용훈,김덕중,이연신,채경수,성백섭,박회식 조선대학교 동력자원연구소 1997 動力資源硏究所誌 Vol.19 No.1

The objective of this thesis is to investigate the influence of the initial residual stress on the fatigue crack growth after the distribution of the initial residual stress is measured when the crack is growing from the compressive residual stress to the tensile residual stress field. In the case of as welded material, respective of load ratio, the span of the fatigue is the shortest in base metal, while in weld metal and HAZ, the crack growth was retarded due to the effect of the compressive residual stress at the crack tip as well as the span of the crack is longer than base metal. In region II that is in stable growth state of the fatigue crack, da/dN=C(ΔK)^m of power law was satisfied. Also, it was considered that the value of m is not affected by residual stress. Superimposing welding residual stress intensity factor K_res on ΔK, the value of ΔK_eff calculated was lower than ΔK in the same value of da/dN, while the ΔK_eff is almost the same at the high ΔK.

건 황색종의 가족력과 관상동맥질환을 갖는 이형집합 가족성 고 콜리스테롤혈증 1례

백승훈,형근영,김경년,조정구,이경근 圓光大學校 醫科學硏究所 1997 圓光醫科學 Vol.13 No.1-2

Familial hypercholesterolemia is a common autosomal dominant disorder with serious health consequences such as the coronary heart disease, in western area affecting approximately 1 in 500 persons in the heterozygous form, is caused by a mutation in the gene for the LDL(low density lipoprotein) receptor. A-45-years old male came to the hospital because of tendon xanthomas on both elbows, knees, and ankles. He also has retrosternal chest pain intermittently since 5 years ago. 4 kindreds of the patient have tendon xanthomas according to autosomal dominant inheritance. Serum levels of total cholesterol and triglyceride were 359 ㎎/dL, 103 ㎎/dL respectively. Lipoprotein electrophoresis showed type Ⅱa pattern. Treadmill exercise test revealed angina pectoris. The case of familial hypercholesterolemia who has familial inheritance of tendon xanthoma is rarely reported in Korea. We report this case with a review of the related literature

골절 및 탈구 없는 경추손상의 치료

성경훈,김상진,강재규,도종웅 대한신경외과학회 1989 Journal of Korean neurosurgical society Vol.18 No.7-12

The authors analized the 98 cases of cervical spine injuries without fracture or dislocation by hyperflexion/hyperextension of the neck. The peak incidence of the age was in the second to fourth decades(69.4%). There was a male preponderance with a sex ratio of 1.8:1. Sources of trauma were motor vehicle accident, object falling on and motorcycle accident in the order of frequency. The common mechanisms of injury were flexion-extension, extension and flexion injury in the order of frequency. There were 10 cases of cervical cord injury without fracture or dislocation and operative management was given in 6 cases of them. The most common preexisting desease was congenital cervical stenosis. Surgical modality such as laminectomy, laminoplasty and anterior decompressive procedure made them improved. The authors discuss the mechanism of injury and surgical management of the patients with cervical cord injury in the abscence of concomittent fracture or dislocation.