고압맥동 평류자극이 가토 상처치유에 미치는 영향

김식현,박래준,권혁철 한국전문물리치료학회 1996 한국전문물리치료학회지 Vol.3 No.3

Test strip과 Chlorophyll meter를 이용한 토마토의 신속한 영양진단

김권래,정한울,김계훈 한국농화학회 2003 Applied Biological Chemistry (Appl Biol Chem) Vol.46 No.2

본 연구는 지금까지 제시된 여러 가지 간이 식물영양 진단 방법들 중 test strip과 chlorophyll meter의 이용가능성을 검토하고 실제 이용 방안을 모색하고자 수행되었다. 본 실험에서는 양액의 N, P, K 수준을 달리하여 토마토를 재배하면서 생육시기별로 specific color difference sensor value(SCDSV), 엽병 즙액 중 NO_3, PO_4, K의 함량을 측정하였다. 실험 결과 N, P, K 함량의 변화보다 더 민감하였다. Test strip을 이용하여 측정한 토마토 엽병 즙액 중 NO_3, PO_4, K함량 변화가엽 중 total-N, P, K의 농도와 고도의 일차상관관계를 나타내었다. 지금까지 여러 연구를 통해 확립된 토마토의 엽 중 total-N, P, K의 적정 함량을 희귀식에 대입하여 구한 즙액의 적정 NO_3, PO_4, K의 함량은 각각 3.4~5.9, 0.3~0.5, 3.6~6.5 g/l였다. Chlorophyll meter를 이용하여 측정한 SCDSV는 엽 중 total-N 함량을 희귀식에 대입하여 계산한 결과 적정 SCDSV는 36.0~40.0이었다. 본 연구 결과 test strip과 chlorophyll meter는 토마토의 신속한 영양 진단에 이용 할 수 있을 것으로 판단된다. This study was performed to develop a more rapid and simple nutrient diagnosis method of plants than the conventional leaf analysis method. Tomato (Lycopersicon esculentum Mill. cv. super momotaro) was planted in the mixed media produced by nidxing perlite and rock wool at I : I (v/v) ratio. The Yamazakki nutrient solutions for cucumber and tomato were supplied to the media using the rnicro-drip irrigation system. Experimental plots produced consisted of no fertilization, deficient fertilization, adequate fertilization and surplus fertilization for N, P and K, respectively. Each experimental plot was replicated four times. Specific color different sensor values (SCDSV) measured by the chlorophyll meter were closely related to total-N concentrations in the leaves measured by the conventional method. Nitrate, PO, and K concentrations in petiole sap measured by test strips (Reflectoquant, Merck, Germany) showed a significant relationship with total-N, P and K concentrations in leaves. The linear regression equations between NO,, PO, and K concentrations in petiole sap and total-N, P and K concentrations in the leaves were prepared. The optimum levels of NO,, PO, and K in petiole sap were obtained by plugging the optimum concentrations of total-N, P and K in the leaves by other researchers into the equations. In conclusion, the SCDSV by the chlorophyll meter and concentrations of NO,, P and K in petiole sap measured by the test strips would be suitable for rapid estimation of plant nutrient status.

파악력 평가시 10%법칙 적용의 이용성에 관한 연구

배성수,박래준,권혁철,김진상 大邱大學校 再活科學硏究所 1992 再活科學硏究 Vol.10 No.1

The purpose of this study was test utility of 10% rule in assessment of hand grasp strength. The 10% rule states that the dominant hand possesses a 10% greater grip strength than the non-dominant hand. The subjects for this study consisted of 50 male 50 female college students who agreed participate in this study. Grasp or grip strength was measured with a factory-calibrated hand dynamometer(Preston Co. production) for cylindrical grasp and JAMAR dynamometer for tip pinch strength. Results showed an 14.60% strength of cylindrical grasp and 10.61% strength of tip pinch difference between dominant and non-dominant hands. Second showed that the 10% rule is valid for right handed person. except cylindrical strength of female and tip pinch strength of male. Further research is necessary to determine the characteristics according to hand size and graspping time.

엔로플록사신 액제의 닭유래 병원세균에 대한 시험관내 항균효과 시험

윤효인,박병권,조준형,정상희,박경환,장범수,김종춘,황윤환,임종환,이내경,박승춘 충남대학교 수의과대학 동물의과학연구소 2000 動物醫科學硏究誌 Vol.8 No.-

In this study the antimicrobial spectrum and sensitivity of a liquid formulation of enrofloxacin against the major six pathogenic bacteria isolated from the diseased poultry in Korea were evaluated in comparison with ciprfloxacin (CFX), gentamicin (GM) and penicillin (PC). A liquid form of enrofloxacin, a test material and ciprofloxacin showed at least 83% antibacterial activity against all of six test pathogenic microorganisms at the fixed concentration of 10 ㎍/㎖. Gentamicin and penicillin revealed much lower antibacterial activity at the same condition. We evaluated the liquid form of enrofloxacin as having widespread antibacterial spectrum against poultry infections. The liquid form of enrofloxacin showed potent antibacterial activity, with the MIC range being 0.12∼2 ㎍/㎖ against Gram positives, 0.06∼2 ㎍/㎖ against Gram negatives and 0.5∼2 ㎍/㎖ against Mycoplasma spp. These values were equivalent to or somewhat higher than those of ciprofloxacin, but much lower than those of gentamicn and penicillin. This new liquid form of enrofloxacin would find its way in application of mixing with drinking water for the prevention and treatment of diverse infections in chickens.

엔로플록사신 액제의 닭 호흡기 및 소화기 감염증에 대한 예방 및 치료효과

윤효인,박병권,조준형,정상희,박경환,장범수,김종춘,황윤환,임종환,이내경,박승춘 충남대학교 수의과대학 동물의과학연구소 2000 動物醫科學硏究誌 Vol.8 No.-

We evaluated the efficacy of the liquid form of enrofloxacin against poultry respiratory and digestive infections, the major problems in the poultry industry, from diverse diagnosis viewpoints. Results obtained through this study were as follows: 1. The liquid form of enrofloxacin showed good acceptability to poultry owing to no abhorrence to the drug by chickens, which indicated its suitability for mixing in drinking water. 2. The application of the enrofloxacin formulation improved the productivity of the chicken farm to a great extent by lowering the death toll of chicken raised in the farm. 3. The use of the drug shortened the days to the market, and increased the body weight at the time of marketing. 4. Preventive and therapeutic effects of the liquid enrofloxacin were observed higher than ampicillin, a major antibiotic used in poultry farming. From above results, the liquid form of enrofloxacin would find its use for the prevention and treatment of digestive and respiratory infections, let alone the growth promotion and feed efficiency, especially in the chicken farming practice.

工業敎育大學 敎育改善에 관한 硏究(Ⅲ)

宋周鎬,李昌岬,洪元杓,孟琦錫,任洪彬,李廷玟,李載元,李來烈,權五憲,金振淳,李文洙 충남대학교 공업교육연구소 1982 論文集 Vol.5 No.1

This paper aims at providing a concrete plan to improve technical and vocational teacher education in the College of Industrial Education of Chungnam National University. It is intended to propose a practical four-year regular and short-term course. Also, the estimated required facilities is included in this study as well as their management. The main conclusions and recommendations are summarized as follows; 1) The numbers of students enrollment should be reduced to 220 students which is the approximate number of future demand. 2) In order to offer to the students a broader education and to cope with the increase/decrease in demand of technical and vocational teacher within a specific field, the 8 department existing at the present (Department of Architecture Engineering Education, Civil Eng. Educ., Metallurgical Eng. Educ., Mechanical Eng. .Educ., Electrical Eng. Educ., Electronic Eng. Educ., Industrial Chemistry Educ. and Industrial Technology Educ.) would be combined into 5 (Department of Construction Engineering Education, Mechanical Eng. Educ., Electrical Eng. Educ., Industrial Chemistry Educ. and Industrial Technology Educ.). 3) The short-term course program is recommened to provide additional training and education to those candidates who already have experience in technical fields to meet an occasional demand. 4) It is necessary to add the Teaching Profession Section in the administrative organization of the College.

Roles of Host Nonhematopoietic Cells in Autoimmunity and Donor Cell Engraftment in Graft-versus-host Disease

Kim, Ju-Yang,Park, So-Hye,Kim, Hyun-A,Jung, Dae-Hee,Kim, Hyun-Ju,Choi, Hye-Jeong,Cho, Hong-Rae,Kwon, Byung-Suk The Korean Association of Immunobiologists 2010 Immune Network Vol.10 No.2

Background: Graft-versus-host disease (GVHD) is initiated when alloreactive donor T cells are primed by host APCs to undergo clonal expansion and maturation. Since there is a controversy regarding the role of nonhematopoietic cells in GVHD, we wanted to investigate the influence of MHC disparity on nonhematopoietic cells on the pathogenesis of GVHD in the MHC-haplomismatched C57BL/6 ($H-2^b$) or DBA/2 $(H-2^b){\rightarrow}$unirradiated ($C57BL/6{\times}DBA/2$) $F_1(BDF_1;\;H-2^{b/d})$ murine model of acute GVHD (aGVHD) or chronic GVHD (cGVHD). Methods: We generated ($BDF_1{\rightarrow}C57BL/6$), ($BDF_1{\rightarrow}DBA/2$), and ($BDF1{\rightarrow}BDF_1$) chimeras and examined GVHD-related parameters and donor cell engraftment in those chimeras. Results: Using this experimental system, we found that 1) severe aGVHD across MHC Ag barrier depends on the expression of nonhematopoietically rather than hematopoietically derived alloAgs for maximal GVHD manifestations; 2) host APCs were sufficient to break B cell tolerance to self molecules in cGVHD, whereas host APCs were insufficient to induce autoimmunity in aGVHD; 3) donor cell engraftment was greatly enhanced in the host with MHC-matched nonhematopoietic cells. Conclusion: Taken together, our results provide an insight into how MHC disparity on GVHD target organs contribute to the pathogenesis of GVHD.

Anti-Angiogenic Activity of Acalycixenolide E, a Novel Marine Natural Product from Acalycigorgia inermis

Kwon, Ho Jeong,Kim, Jin Hee,Jung, Hye Jin,Kwon, Yong Guen,Kim, Min Young,Rho, Jung Rae,Shin, Jong Heon 한국미생물 · 생명공학회 2001 Journal of microbiology and biotechnology Vol.11 No.4

Angiogenesis is known as a crucial process in the growth and spreading of tumor cells. Accordingly, the effective inhibition of this process would appear to be a promising way to cure angiogenesis-related diseases, including cancer. This study demonstrates that acalycixenolide E (AX-E) from the marine organism Acalycigorgia inermis exhibits a potent antiangiogenic activity both in vitro and in vivo. AX-E inhibits the bFGF-induced proliferation of HUVECs in a dose dependent manner, along with the bFGF-induced migration, invasion, and tube formation of HUVECs. Moreover, AX-E potently inhibits the in vivo neovascularization of the chorioallantoic membranes (CAMs) of growing chick embryos. Interestingly, AX-E suppresses the expression of metalloproteases 2 and 9, yet shows no effect on their activities. The novel chemical structure and potent anti-angiogenic activity of AX-E will be of great value in elucidating the molecular mechanism of angiogenesis as well as in the development of a novel anti-angiogenic drug.

Future Prospects of Health Management Systems Using Cellular Phones

Kim, Hun-Sung,Hwang, Yunji,Lee, Jae-Ho,Oh, Hye Young,Kim, Yi-Jun,Kwon, Hyeon Yoon,Kang, Hyoseung,Kim, Hyunah,Park, Rae Woong,Kim, Ju Han Mary Ann Liebert 2014 TELEMEDICINE JOURNAL AND E HEALTH Vol.20 No.6

<P>Cellular phones enable communication between healthcare providers and patients for prevention, diagnosis, and treatment of diseases. However, few studies have examined the user-friendliness or effectiveness of cellular phone-based medical informatics (CPBMI) for healthcare.</P>

Fractionated radiation-induced nitric oxide promotes expansion of glioma stem-like cells.

Kim, Rae-Kwon,Suh, Yongjoon,Cui, Yan-Hong,Hwang, Eunji,Lim, Eun-Jung,Yoo, Ki-Chun,Lee, Ga-Haeng,Yi, Joo-Mi,Kang, Seok-Gu,Lee, Su-Jae Japanese Cancer Association 2013 CANCER SCIENCE Vol.104 No.9

<P>Glioblastoma remains an incurable brain disease due to the prevalence of its recurrence. Considerable evidence suggests that glioma stem-like cells are responsible for glioma relapse after treatment, which commonly involves ionizing radiation. Here, we found that fractionated ionizing radiation (2 Gy/day for 3 days) induced glioma stem-like cell expansion and resistance to anticancer treatment such as cisplatin (50 μM) or taxol (500 nM), or by ionizing radiation (10 Gy) in both glioma cell lines (U87, U373) and patient-derived glioma cells. Of note, concomitant increase of nitric oxide production occurred with the radiation-induced increase of the glioma stem-like cell population through upregulation of inducible nitric oxide synthase (iNOS). In line with this observation, downregulation of iNOS effectively reduced the glioma stem-like cell population and decreased resistance to anticancer treatment. Collectively, our results suggest that targeting iNOS in combination with ionizing radiation might increase the efficacy of radiotherapy for glioma treatment.</P>