건진센터 수검자 자료를 이용한 비만지표에 대한 연구

김상만,최희정,이득주,김광민,윤수진 대한비만학회 1997 The Korean journal of obesity Vol.6 No.2

We have examined l5145 persons(7468 men 7677 women) to determine the role of Obesity Index(body mass index, WHR, body fat percent) on the risk of various chronic disease. All the subjects were pooled from Health Examination Center who took the annual health examination from June, 1994 through Jan, 1997, BMI(Body mass index, kg/㎡), WHR(Waist hip ratio) were measured and correlated with the frequency of chronic disease. In order to evaluated the BMI, WHR, Body Fat as an independent factors on rnorbidity, analysis of covariance was applied adjusted for age. The risk of variows chronic diseases were also analyzed with obesity, defined by BMI above 26kg/㎡ (men), 25kg/㎡ (women), by logistic regression adjusted age and sex. Risk of hypertension was 2.6 with 95% eonfidence interval of 1.9-2.8 in obese group. Risk of diabetes mel1itus, hypercholesterolemia, hypertriglyceridemia, gall stone, fatty liver were 3.2(2.3-4.4), 1.2(0.9-1.4), 2.1(1.7-2.8), 1.4(1.1-2.6) and 1.3(0.8-2.3) respectiveiy. The risk of various chronic diseases were also analyzed with obesity, WHR above 0.9(men), 0.81(women), by logistic regression adjusted age and sex. Risk of hypertension was 1.7 with 95% confidence interval of 1.4 -2.1 in obese group. Risk of diabetes mellitus, hypercholesterolemia, hypertriglyceridemia, gall stone, fatty liver were 3.1(2.3-4.0), 1.2(0.9-l.4), 1.4(1.1-2.6), 2.4(l.8-4.8) and 2.1(1.2-4.1) respectively. The BMI, WHR were independent risk factors for various chronic diseases.

전격성 경과를 취한 만성 호산구성 폐렴 환자 1예

윤호상,진춘조,유광하,이상엽,이수인,정상만,김선두,이순제,이길도,전혜정 건국대학교 의과학연구소 2000 건국의과학학술지 Vol.10 No.-

Chronic eosinophilic pneumonia(CEP) is a rare disease of unknown etiology characterized by chronic infiltration of the lung with eosinophils. It presents with profound systemic symptoms comprising fever, night sweats, weight loss, dyspnea and blood eosinophilia with nonsegmental air-space consolidation confined to the outer third of the lung, the "photographic negative of pulmonary edema". Histopathologic features of chronic eosinophilic pneumonia are intraalveolar and interstitial infiltrations with eosinophils, histiocytes, giant cells, scattered lymphocytes and plasma cells. Glucocorticoid therapy cause prompt resolution of symptoms as well as disappearans of blood eosinophils, elevated serum Ig E levels and the roentgenographic lesions. Infrequent radiographic findings include nodular infiltrates, consolidations, cavitations, atelectasis and pleural effusions. Deaths from CEP although rare, have been reported, but the majorities of CEP have benign courses and do not need a therapy with ventilator. We report a case of chronic eosinophilic pneumonia, which had a sudden course associated with diffuse pneumonic consolidations on the both lung and bilateral pleural effusion.

자동차용 센서응용을 위한 CMOS 열전대 공정 개발

이광만,박세광,도양회,Liu, C.C. 경북대학교 센서기술연구소 1996 연차보고서 Vol.1996 No.-

자동차용 센서응용을 위하여 CMOS공정을 이용한 마이크로 열센서의 기초 제조공정을 개발하고 CMOS공정과 호환성을 갖는 열센서의 마스크 설계와 공정 설계를 하였다. LPCVD법, APCVD법 및 실리콘 미세가공기술을 각각 활용하여 열전도율이 낮고 내부응력이 최소화된 NON절연막 다이아프램을 형성하였다. TMAH용액의 농도와 온도를 3∼25wt%와 80∼90℃ 범위내에서 각각 변화시키면서 실리콘의 식각특성을 조사하였다. 그리고 NON절연막의 기계적 및 열적응력을 NON 캔티레버와 빔의 조합으로 이루어진 시험패턴의 식각을 통하여 각각 조사하였다. 그리고 CMOS 구동회로를 내장한 마이크로 열센서의 기초연구를 하였다. A basic fabrication process of micro thermal sensor was developed and the related mask pattern and process were designed by standard CMOS process for the automotive sensor application. An NON dielectric diaphragm with low thermal conductivity and minimum internal stress was fabricated by LPCVD, APCVD methods and silicon micromachining techniques. Etching characteristics of silicon in the TMAH solution was studied with the TMAH concentration and temperature variation of 3∼25wt% and 80∼90℃, respectively. Mechanical and thermal stress of the NON layer were investigated by using a test pattern which composed of cantilever and beam. And a micro thermal sensor with on-chip CMOS driving circuits was studied.

CVD 다이아몬드 박막의 열전도 특성

이광만,고정대,최치규 제주대학교 산업기술연구소 2001 尖端技術硏究所論文集 Vol.12 No.1

Diamond has outstanding thermal properties that make it the material of choice for heat spreading applications in microelectronic devices. In order to asses thermal properties of diamond films grown by microwave plasma CVD method, we have applied an ac thermal conductivity measurement technique where films are thermally excited at frequency w while the thermal response is measured at the third harmonic via a lock-in amplifier. This method is insensitive to errors due thermal noise. Before the application to diamond, the measurement technique was tested on fused silica and sapphire. The results were in good agreement with published values. The thermal conductivity of CVD diamond films were measured to be around 3 W/cm·K.

부여 백제시대 가마터의 고고지구자기 연구

이윤수,서광수,서만철 공주대학교 문화재보존과학연구소 2004 문화재과학기술 Vol.3 No.1

충남 부여군 가마터에 대한 고고지자기 연구를 실시하였다. 13개의 가마 시료로부터 구한 특성잔류자화는 열화학작용에 의해서 생성된 자철석에 의해서 수행되며, 가마가 575℃이상 가열된 후 식으면서 그 당시의 지구자기장에 의해서 획득된 것으로 밝혀졌다. 이번 연구에서 구한 특성잔류자화의 그 평균편각과 평균복각은 각각 3.9˚E와 39.4˚ (a_(95)=3.2˚)로서, 한반도의 시험적 영년변화곡선에 대비하여 구한 특성잔류자화의 획득 시기는 서기 1,583년(+44년, -36년)이다. The archaeomagnetic study is examined to determine archomagnetic age of the kiln located in Buyeo area, Chungnam province. The results document that the characteristic remanent magnetization(ChRM) for 13 samples is carried by magnetite grains formed by a thermochemical activity during cooling from more than 575˚C. The Site mean direction (declination and inclination) for the ChRM is 3.9˚E and 39.4˚ (a_(95)=3.2˚). We conclude that the ChRM acquired in A.D. 1,583 (+44 yr, -36 yr), correlating the t-KPSV (tentative Korea Paleoselcular Variation) curve.

ISFET의 제조공정 및 그 동작특성

이광만,서화일,손병기 경북대학교 센서기술연구소 1990 센서技術學術大會論文集 Vol.1 No.1

ISFET's fabrication process have been designed and computer simulated with SUFREM-II, and their results are good agreement with each other. ISFET chip has been fabraicated by using the ISRC's standard "3um CMOS process". A two-step TCA oxidation for the gate oxide and multilayer encapsulation using silicone rubber was specially used for the improvement of the stability of the ISFETs. The C-V measurement of gate oxide and the AES analysis of gate nitride were performed.The measured sensitivities of the pH-ISFETs are 43 mV/pH and 54 mV/pH without and with HF treatment, respectively.

용접공들의 면역능에 관한 연구

이수일,조봉수,김영욱,고광욱,조원근,김영실,강수용,황인경,조병만,김돈균 大韓産業醫學會 1997 대한직업환경의학회지 Vol.9 No.1

The authors examined human immunity indicators such as CD4, CD8, Natural Killer(NK) cell, IgG, IgA, and IgM, and heavy metals such as Pb, Cr, Cd to evaluate the health hazard of welders. We selected total 126 male subjects, 60 welders who had more than 5 year working history as an exposure group, and 66 office workers and medical college students as a control group. This immunity evaluation approach is the first newly designed study that has never been tried in past studies on welder's heath evaluation. And the results were as follows. 1. Total lymphocyte count of peripheral blood was significantly higher in welder group, 2,615±650 ea/㎕ compared with 2,368±681 ea/㎕ in control group(p>0.05). 2. The proportion of CD4, CD8, NK cell in welder group was 37.5±9.4%, 24.0±8.8%, and 21.0±9.5%, respectively, and 35.5±6.5%, 25.0±6.9%, and 19.6±8.8% in control group. CD4 and NK cell were slightly higher, and CD8 was slightly lower in welder group. but there was no statistical significance between two groups(p≥0.05). 3. IgG, IgA, and IgM in welder group were 15.9㎎/㎗, 2.7㎎/㎗ and 1.5㎎/㎗, respectively, and 15.6㎎/㎗, 2.9㎎/㎗ and 1.7㎎/㎗ in control group. There was no statistical significance between two groups(p≥0.05). 4. Blood lead, cadmium and chromium concentrations were 4.2±1.8㎍/㎗, 0.4±0.38㎍/㎗, 1.2±0.6㎍/㎗ in welder group and 3.2±1.7㎍/㎗, 0.44±0.29㎍/㎗, 1.1±0.6㎍/㎗ in control group, respectively, and these value were within normal ranges.

유착성 견관절낭염 환자에서 견갑상신경과 견갑배신경의 병합 차단술의 효과

이삼규,노성만,선광진 대한스포츠의학회 2000 대한스포츠의학회지 Vol.18 No.2

Objective : To investigate the effect of combined nerve block of suprascpular and dorsal scapular nerve as a means of pain management in adhesive capsulitis of shoulder. Method : Of the 55 patients with adhesive capsulitis of shoulder, 30 patients〔age: 62.55(47.2-72-7) years, symptom duration: 60(3-365) days, 12 males and 28 females〕were treated with combined nerve blocks of suprascpular and dorsal scapular nerve as a means of pain management, But, 25 patients〔age : 54.0(25.0-75.0) years, symptom duration: 90(3-730)days, 11 males and 14 females〕were not treated with nerve block. We measured the ROM of flexion and external rotation(˙) as degree via AMA method and VAS(mm). as a degree of shoulder pain weekly. We defined therapeutic duration as above 80% recovery of normal active ROM in flexion and external rotation and below 40mm in VAS. Results : 1) There were significantly decreased VAS from 90mm to 30mm in postnerve block group during serial follow-up exam(p<0.001). 2) There were significantly increased ROM of shoulder flexion from 150˚ to 170˚ in post-nerve block group duing serial follow-up exam (p<0001). 3) There were significantly increased ROM of shoulder external rotation form 40˚ to 60˚ in post-nerve block group during serial follow-up exam(p<0.001). 4) There was significantly increased in exercise compliance(sself-exercise time duration per day) from 60.0 minute to 92.0 minute and decreased in therapeutic duration from 6 weeks to 3 weeks(p<0.001). Conclusion : We concluded that the combined nerve blocks of suprascapular and dorsal scapular nerve were simple, safe, and effective procedure and beneficial to pain relief and shortening of the theraprtic duration of rehabilitative management in patients with adhesive capsulitis of shoulder.

실리콘 미세가공 기술을 이용한 마이크로 진공 센서

이광만,고성택,김영민,고희선 濟州大學校 産業技術硏究所 1998 산업기술연구소논문집 Vol.9 No.1

A micro-vacuum sensor has been fabricated by using silicon micromachining techniques and platinum thin film. NON insulator was deposited by LPCVD and APCVD methods. The insulator diaphragm was fabricated by silicon anisotropic etching in TMAH solution. Thin film platinum heater and temperature detector were deposited by rf sputtering method and patterning was performed by means of lift-off method. Deposited platinum heater and temperature detector have been shown a linear I-V characteristics. TCR( temperature coefficient of resistance) of thin film platinum heater and temperature detector was about 0.0042/℃. Fabricated vacuum sensor was measured in the range of 1X 10^(-3) Torr to 1X10^(2) Torr. and shows a good linear operating characteristics in the range of 1x1^(-2) Torr에서 1X10^(0) Torr.

자동차 실내 환경제어용 센서시스템 개발

이광만,도양희 경북대학교 센서기술연구소 1997 연차보고서 Vol.1997 No.-

자동차 실내 환경제어용 센서시스템을 개발하기 위하여 마이크로 가스유량 센서와 습도센서를 설계하고 제조공정을 수행하였다. 1차년도의 연구결과를, 바탕으로 가스유량 센서의 경우, 히터와 반도체열전대를 NON 절연막 브리지에 형성한 구조를 하고있다. 습도센서의 경우, 단일 히터만이 NON 절연막 브리지 위에 형성된 간단한 구조를 하고 있다. 이들 마이크로 센서들을 CMOS공정과 실리콘 미세가공기술을 이용하여 제조하였다. 마이크로 센서시스템을 위한 기초연구로 가스유량센서와 습도센서를 동일 칩상에 조합하고 구동회로를 함께 집적한 스마트센서를 설계하였다. 설계된 구동회로와 마이크로 센서를 검증하였다. A micro gas-flow sensor and humidity sensor have been designed and fabricated for the development of the sensor system which can be applicable to the automotive interior environmental control. For the case of gas-flow sensor, a heater and semiconductor thermocouples were formed on the NON bridge based on the results of first research year's. For the case of humidity sensor, it have a simple structure compose of single heater formed on the NON bridge. These micro sensors were fabricated by CMOS process and silicon micromachining techniques. A smart sensor composed of gas-flow sensor, humidity sensor and driving circuits was designed for the basic research. The designed driving circuits and micro sensors were verified.