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      • KCI등재

        南北韓 國史敎科書에 登場하는 國王, 王族의 人物 比較

        김인식,김선규 한국교육과정학회 2000 교육과정연구 Vol.18 No.2

        본 연구는 남북한의 중등학교 국사 교과서에 등장하는 인물 중 국왕·왕족에 대하여 양적인 측면에서는 각 교과서별·시대별 분포와 설명이 있는 인물의 수 및 비율을, 질적인 측면에서는 공통으로 등장하는 인물에 관한 서술을 비교하는 것이었는데, 비교 대상 교과서는 남한의 중학교 및 고등학교 <국사>교과서와 북한의 고등중학교 국사교과서인 <조선력사>였다. 먼저 남북한 국사 교과서에 등장하는 전체 등장 인물의 수 및 비율을 각 교과서별·시대별·유형별로 분류하였다. 이어 남북한 국사교과서에 등장하는 국왕·왕족의 수 및 비율을 각 교과서별·시대별로 양적으로 분석하고, 각 인물의 양적인 비교를 보완하기 위하여 단순 등장 인물과 설명이 있는 인물의 등장 횟수 및 비율도 산출하였다. 아울러 이들 국왕·왕족이 남북한 국사교과서에 공통 및 어느 한쪽에만 등장하는 인물로 분류하여 각 시대별로 나누어 제시하였다. 다음으로 남북한 공통 등장 인물에 대한 질적인 비교는 인물의 '활동 분야·역할'의 측면, 서술 방식·비중'의 측면, 그리고 '인물 평가'의 측면으로 나누어 고찰하되 주로 각 측면별로 남북한이 상이하거나 부분적으로 일치하는 인물의 서술을 중심으로 논의 하였다. 비교의 결과 남북한 국사 교과서의 등장 인물을 양적으로 분석하면 인물의 수는 남한의 <국사>가, 설명이 있는 등장 인물은 북한의 <조선력사>가 더 많았으며, 남북한 공통 등장 인물보다 어느 한쪽에만 등장하는 인물의 수가 더 많았다. 이들 국왕·왕족을 질적으로 비교하면 인물의 '활동 분야·역할'과 같은 사실적 진술보다는, 인물의 '서술 방식·비중' 및 '인물 평가'의 측면에서 상이하거나 부분적으로 일치하는 노력이 요청된다. 하지만 남북한의 국사 교과서에는 이질적인 측면뿐만 아니라 유사하거나 동질적인 부분도 많은 만큼 공통적인 점은 더욱 심화·확대시키고, 차이점에 대해서는 이질성 극복을 위한 보다 적극적인 대처가 필요하다고 본다. The purpose of this study was to analyze the historical characters appearing in national history textbooks of South and North Korea, and to compare their similarities and differences in terms of quantitative dimension and qualitative dimension, In order to achieve these goals, this study overviewed the existing curricular structure and history education of South and north Korea, and analyzed the following three history textbooks ; <Junghak Kooksa> which is the history textbook for middle schools of South Korea, <Kogyo Kooksa> , which is the history textbook for high schools of South Korea, <Josun Ryuksa> which is the history textbook for secondary education of North Korea. As the quantitative approach, this study counted the frequency of all characters appearing in the textbooks, and divided them into a group of commonly appearing characters and a group of characters appearing in one part among three textbooks. Then, the frequency and the rate of all characters' appearance were calculated separatedly and compared with each other. As a result, some quantitative differences were founded in total counts of appearing characters in three textbooks. In total frequency of characters appearing in textbook, the history textbook of South Korea (<Junghak Kooksa> : 393, <Kogyo Koodsa> : 512) contained much more characters than North Korea's (<Josun ryuksa> : 348). And, commonly appearing characters in three comparative textbooks were 133, which amounted to only 18% of total numbers of appearing characters(735). It means that there are lots of differences between south Korea and north Korea in the number of appearing characters. And, as the qualitative approach, this study tried to analyze and discuss the similarities and difference of commonly appearing characters in three textbooks in terms of a character's activity area and role, description and weight of him/her, and historical evaluation of him/her as a whole. As a result, much more similarity was found in character's activity area and role any other aspects. On the other hand, in the aspect of description and weight of a character, difference between three textbooks was much more than similarity, and partially accordant characters were the most in historical evaluation of characters. Nowadays waking to the unification of South and North is faster and faster. So when we compare and study south and north Korean history education and characters in textbooks, we need to study more about 'how same' than 'how different'. Since appearing characters in textbook were deeply connected with their historical background and situation, how to describe a character would greatly influence on the historical interpretation. Therefore, in order to identify the reality of a character, we need a careful analysis on the historical viewpoint of textbook writers. It exceeds. however, the task and the focus of this study. In other word, based on the results of this study, a much more in-depth analysis on types of characters, modes of explaining them, and socio-cultural context should be continued in the future.

      • KCI등재후보

        2009년 인플루엔자 대유행 중 인플루엔자 진료소 방문자의 연령 분포 변화

        김백남,곽이경,문치숙,김연숙,김의석,배인규,염준섭,이창섭,허지안 대한감염학회 2010 감염과 화학요법 Vol.42 No.2

        The pandemic influenza (H1N1 2009) virus, after being introduced in Korea in April, 2009, spread rapidly nationwide in mid-2009. This study was conducted to characterize trend in age distribution of visitors to Flu-clinics during the pandemic. Demographic, clinical and laboratory data of visitors to flu clinic from Week 36 to 52 (August 30 to December 26) of 2009 were retrieved and collected from electronic databases at 9 hospitals. Visitors 0-6, 7-12, 13-18, 19-29, 30-64, and 65 years or more of age were classified into group I to VI, respectively. A total of 107,467 visitors were seen at Flu-clinics for a 17-week study period. Of those, 32,485 were laboratory-confirmed. Antivirals were prescribed for 62,533 visitors. Numbers of visits, prescriptions of antivirals, and laboratory-confirmed cases of the pandemic influenza (H1N1 2009) peaked at Week 44. A large number of visits by group II and III were followed by those of group I and V, especially around the peak. Numbers of visits by group VI were lowest in all hospitals. In some hospitals, higher number of visits lasted longer in children than in adults while vice versa in other hospitals depending on the location. In summary, the pandemic influenza (H1N1 2009) was presumed to peak in late October and involved majorly children and students in Korea. Unique age distribution of visitors to flu clinic was observed in some hospitals.

      • KCI등재
      • SCOPUSKCI등재

        The Effect of Rosiglitazone on the Cell Proliferation and the Expressions of p27 and Skp2 in<i>Helicobacter pylori</i>Infected Human Gastric Epithelial Cells

        Kim, Sung-Soo,Cho, Young-Seok,Kim, Hyung-Keun,Shin, Ok-Ran,Chae, Hiun-Suk,Choi, Myung-Gyu,Chung, In-Sik The Korean Society of Gastroenterology 2010 대한소화기학회지 Vol.55 No.4

        <P>Background/Aims: Ligands for peroxisome proliferator-activated receptorgamma (PPARgamma), a member of the ligand-activated nuclear receptor superfamily, exhibit anti-tumoral effects and are associated with de novo synthesis of proteins involved in regulating the cell cycle and cell survival/death. Helicobacter pylori (H. pylori) is an etiologic agent for gastric adenocarcinoma, and raises the cell turnover of gastric epithelium. The aim of this study was to investigate the effect of PPARgamma ligand rosiglitazone on the cell proliferation and the expressions of p27 and Skp2 protein in H. pylori infected gastric epithelial cells. Methods: We examined the expression of PPARgamma by Western blot in H. pylori infected AGS human gastric epithelial cells. The effect of rosiglitazone on the survival of H. pylori infected AGS cells was assessed by cell viability assay. After the treatment of rosiglitazone in H. pylori infected AGS cells, the expressions of p27 and Skp2 were assessed by Western blot. Results: The expression of PPARgamma protein was increased in H. pylori infected AGS cells. Cell growth was inhibited and decreased in dose- and time- dependent manner in H. pylori infected AGS cells treated with rosiglitazone. A decrease in Skp2 expression and a reciprocal increase in p27 expression were found in dose- and time-dependent manner in H. pylori infected AGS cells treated with rosiglitazone. Conclusions: Rosiglitazone inhibited the growth of H. pylori infected AGS cells. Rosiglitazone attenuated Skp2 expression, thereby promoting p27 accumulation in H. pylori infected human gastric epithelial cells. Further studies will be needed to find the effects of accumulation on cell turnover in H. pylori infection and the role in the H. pylori-associated gastric carcinogenesis.</P>

      • SCIESCOPUS

        Adult invasive pneumococcal disease in the Republic of Korea: Risk medical conditions and mortality stratified by age group

        Kim, Jong Hun,Baik, Seung Hee,Chun, Byung Chul,Song, Joon Young,Bae, In-Gyu,Kim, Hyo Youl,Kim, Dong-Min,Choi, Young Hwa,Choi, Won Suk,Jo, Yu Mi,Kwon, Hyun Hee,Jeong, Hye Won,Kim, Yeon-Sook,Kim, Jeong Elsevier 2018 INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES Vol.74 No.-

        <P><B>Abstract</B></P> <P><B>Objectives</B></P> <P>This study aimed to characterize the risk factors for mortality in adult patients with invasive pneumococcal disease (IPD) stratified by age groups, after implementation of the national immunization program of 23-valent polysaccharide vaccine (PPSV23) for those aged ≥65 years in the Republic of Korea (ROK).</P> <P><B>Methods</B></P> <P>Clinical data and pneumococcal isolates from adult patients with IPD (≥18 years of age) were collected prospectively from 20 hospitals through the nationwide surveillance program from March 2013 to October 2015.</P> <P><B>Results</B></P> <P>A total of 319 patients with IPD were enrolled. Median age was 69 years. Overall in-hospital mortality was 34.2%: 17.1% in those aged 18–49 years, 23.7% in those aged 50–64 years, 33.0% in those aged 65–74 years, and 51.0% in those aged ≥75 years (<I>p<</I> 0.001). In particular, early death within 7days of hospitalization accounted for 60.6% (66/109). While old age (≥65 years), higher Pitt bacteremia score (≥4), and bacteremic pneumonia were independently associated with IPD mortality in all age groups, an additional mortality risk factor of immunocompromised status was identified for patients aged 50–64 years. PPSV23 serotypes accounted for 64.4% (122/189) of the pneumococcal isolates serotyped.</P> <P><B>Conclusions</B></P> <P>This study suggests that vaccine-type IPD continues to place a substantial burden on older adults in the ROK, necessitating an effective vaccination strategy for those at higher risk.</P> <P><B>Highlights</B></P> <P> <UL> <LI> National immunization of the elderly with the 23-valent polysaccharide vaccine (PPSV23) was implemented in Korea in 2013. </LI> <LI> Overall in-hospital mortality was 34.2% for adult invasive pneumococcal disease (IPD) and 51.0% for patients ≥75 years of age. </LI> <LI> Mortality risks were older age, higher bacteremia score, and immunocompromised status. </LI> <LI> An effective vaccination strategy for those at higher risk of IPD is needed. </LI> </UL> </P>

      • 고형배지의 종류가 수경재배 멜론의 품종별 과실의 생육과 품질에 미치는 영향

        전하준,황진규,김인규,손미자 대구대학교 생명과학연구소 2004 생명과학연구 Vol.3 No.1

        In order to examine how growth substances influence to fruit growth and its quality, we cultivated 3 different kinds of melons which grown in hydroponic system into 3 different types of growth substances, such as perlite, perlite/rock wool and rock wool/perlite. In this experiment, “Siroi Kagayaki”, showed no significant difference in fruit weight and its diameter in any of growth substances, but higher in plant height in perlite/rock wool than Perlite. In case of “TS-1806”, there were no significant differences in soluble solids, fruit weight and diameter in all the substances. However, it showed longer in fruit length in rock wool / perlite than that in perlite/ rock wool. In addition, the soluble solids in placenta and flesh were higher in perlite than those in rock wool/perlite.

      • 통조림용 가다랑어육의 식품성분

        오광수,김정균,김인수,이응호,김복규 國立統營水産專門大學 附設 水産科學硏究所 1990 수산과학연구소보고 Vol.2 No.-

        가다랑어 혈합육을 보다 효율적으로 이용하기 위한 일련의 기초연구로서, 가다랑어 혈합육의 지질성분, 함질소엑스분 및 구성아미노산 등을 보통 육과 함께 분석하여 비교, 검토하였다. 보통육은 혈합육에 비해 수분, 조단백질 함량은 약간 많은 반면, 조지방과 회분 함량은 혈합육이 약간 많았다. 휘발성염기질소량은 보토육이 22.7mg/100g, 혈합육이 46.9mg/100ㅎ으로 혈합육이 보통육에 비해 선도저하가 훨씬 빨랐다. 보통육과 혈합육의 총지질 조성은 각각 중성지질 79.7%, 71.9%, 당지질, 6.8%, 9.5%, 인지질13.5%, 18.6%로 이루어져 있었다. 중성지질의 성분은 free fatty acid ac triglyceride, 인지질은 phosphatidyl ethanolamine, phosphatidyl, 인지질은 phosphatidyl choline이 주성분이었고, lysogud 인지질의축적도 확인되었다. 총지지르 중성, 당 및 인지질의 축적도 확인되었다. 종지질, 중성, 당 및 인지질의 지반산 조성에서 보통육은 16:0 및 18:1을 주체로 한 포화산 및 모노엔산의 조성비가 혈합육보다 높았으며, 혈합육은 폴리엔산, 특히 22:6의 비율이 월등히 높았다. 16:0. 18:0, 18:1, 20:5 및 22:6 등이 주요 구성지방산이었다. 유리아미노산의 조성은 총함량에서 보통육 쪽이 많았고, 보통육에는 histidine, 혈합육에는 tauring의 보통육에서는 680.9mg.100g 정도 전존해 있었으나, 혈합육에서는 IMP의 분해가 급속히 진행되어 73.1mg/100g에 지나지 않았다. TMAO 및 TMA는 보통육에 비해 혈합육에 휠씬 많이 함유되어 있었고, total creatinine은 보통육 쪽이 많았다. 구성아미노산의 조성은 양시료 간에 별차이가 없었고, glutamic acid, aspartic acid, lysine, leucine, alanine, isoleucine 및 arginine 등이 주요 구성아니노산이었다. The lipid components, nitrogenous extracts and amino acids of dark muscle(DM) of skipjack (Katsuwonus pelamis) were analyzed and compared with those of white muscle(WM). WM was higher in moisture and crude protein content, and lower in crude lipid and ash content than those of DM. Contents of volatile basic nitrogen in WM and DM were 22.7mg/100g and 46.9mg/100g. Total lipid(TL) of WM and DM consisted of 79.7%, 71.9% neutral lipid(NL), 6.8%, 9.5% glycolipid(GL), and 13.5%, 18.6% phospholipid(PL), respectively. NL was mainly composed of free fatty acid, triglyceride, and PL was mainly occupied by phosphatidyl ethanolamine, phosphatidyl choline. Also lysophosphatidyl choline and lysophosphatidyl ethanolamine were identified in PL. In fatty acid composition of TL, NL, GL and PL, WM revealed higher contents in saturates and monoenes such as 16 : 0, 18 : 1, while DM showed higher contents in polyenes such as 22 : 6 especially. The major fatty acids of these samples were generally 16 : 0, 18 : 0, 18 : 1, 20 : 5 and 22 : 6. Contents of total free amino acids from WM and DM were 5,982.3mg/100g and 4,450.7mg/100g (dry base). Of free amino acids, Tau concentration was much higher in DM than in WM, Ala, Gly, Met, Arg, Thr were also high in DM. But His was much higher in concentration in WM. Content of inosinic acid(IMP) in WM(680.9mg/100g) was higher than that of DM(73.1mg/100g). The degradations of IMP proceeded very rapidly in DM. DM contained much higher trimethylamine oxide and trimethylamine than those of WM. The profile of combined amino acids in these samples were very similar, and main amino acids were Glu, Asp, Lys, Ala, Ile and Arg.

      • SCOPUSKCI등재

        만성 궤양성 대장염의 추적관찰 - 단기적 치료 반응 및 재발율을 중심으로

        장동경(Dong Kyung Chang),이국래(Kook Lae Lee),김재규(Jae Gyu Kim),김용태(Yong Tae Kim),정현채(Hyun Chae Jung),송인성(In Sung Song),최규완(Kyoo Wan Choi),김정룡(Chung Young Kim),박재갑(Jae Gahb Park),이풍렬(Poong Lyul Rhee),최상운(Sa 대한소화기학회 1994 대한소화기학회지 Vol.26 No.6

        N/A Our retrospective study on 240 cases with chronic ulcerative colitis in Seoul National Uni- versity Hospital spanning from January,1975 to December,1993 revealed the following results. According to the extent of disease, there was 27.5% in proctitis, which was more frequent than that of the previous domestic reports, 15.8% in distal, 22.9% in left and 31.7% in exten- sive colitis. According to the severity of disease, there was 47.5% in mild, 32.9% in moderate and 19.6% in severe disease. There was a positive correlation between severity and extent of disease. The extraintestinal complications were not related with the extent, or severity. Howev- er 3 cases(1.3%) of toxic megacolon appeared in moderate or severe extensive colitis, one of which progressed to perforation. Two cases(0.8%) of mortality were noticed, one caused by perforation, the other by operation related complication. There was not a single case of colon cancer developed during follow up period. Most cases showed excellent short term response to medical treatment; the symptomatic remission rates were 90.3%, 85.7%, 72.9% and 58.9% in order of proctitis, distal, left and extensive colitis, and the endoscopic remission rates were 78.8%, 50.0%, 59.1% and 30.0% respectively. Higher remission rates corresponded with lower extent of the disease. According to the severity, the symptomatic remission rates of milder dis- ease were significantly higher. The cumulative relapse rates were 38.7% in 1 year, 62.4% in 2 years, 73.3% in 3 years and 81.9% in 5 years, which were not related to the extent but in- creased according to the severity. The cumulative operation rates were 5.0% in 1 year, 7.6% in 2 years, 10.2% in 3 years and 15.9% in 6 years. The emergency operation accounted for only 22.2% of all operation and the others were elective ones. The most frequent indication of surgery was medical intractability which was determined after mean 35 days of intensive med- ical therapy. We concluded that severity and extent of ulcerative colitis had predictive value of the responses to medical treatment or relapses, furthermore despite the high relapse rates, medical therapy was the first line treatment because of its high remission rates on a short- term base. (Korean J Gastroenterol 1994; 26: 907 918)

      • 시멘트 分産劑 및 高流動化劑를 使用한 모르터의 諸 性質에 關한 實驗的 硏究

        金成完,朴仁圭 충남대학교 농업과학연구소 1984 農業技術硏究報告 Vol.11 No.1

        This study was the contrast of the compressive strength, the tensile strength, the reducing ratio and the flow of mortar using dispersing agent and high fluid admix. 1. The admix ratio of chemical admixtures espressing maximum strength appeared the same result; high fluid admix SP was 0.6%, the dispersing agents LG and C211 were 0.2%. SK was 0.3%, C376 was 0.5%, But two or three times more than standard quantity made the strength's fast lowness, which influenced bad to wateriness and retard the soli-dification. 2. When proper quantity of chemical admixture was used, the increment of compressive strength was as follows, High fluid admix SP was 40.7% and the average increasing rate of dispersing agents(C211 was 19.5%, LG was 19.1%, C376 was 17.9 %) was 18.7% more than normal mortar in the condition of 7 days. Also, in the condition of 28 days, high fluid admix SP was about 24.4% and the average of dispersing agents(LG was 21.1%. C211 was 16.4%, SK was 11.1%, C376 was 7.6%) was 14.1%. 3. When proper quantity of chemical admixture was used, the increment of tensile strength was as follows. High fluid admixture SP was 26.6% and the average increasing agents(SK was 16.0%. C376 was 14.7%, LG was 10%, C211 was 5.8%/n) was 11.6%. Also, in the condition of 28 days. high fluid admix SP was 16.5% and the average increasing rate of dispersing agent(LG was 19.1%, SK was 10.6%, C211 was 10.1 %. C376 was 8.7%) was 12.1%. 4. As for the reducing ratio of each dispersing agent, he flow of mortar was less than the slump of concrete. That is; the reducing ratio of concrete was 15% adding each dispersing agent, but the reducing ratio of mortar was in the range of from 5.8% to 13.5% in 1 : 1 mixture, from 7.6% to 14.2% in 1 : 2, from 9.5% to 18.8% in 1 : 3. 5. The fluidity of each chemical admixture was as follows. High fluid admix SP in the condition of 1 : 1 and 1 : 2 showed the best result than other dispersing agent and 1 : 3 showed the same result like other agents, Therefore these good dispersing agents were suitable in the prepact concrete construction using intrusion mortar.

      • KCI등재

        우라늄 투여후 간조직에서의 효소활성도의 변화

        김국찬,이강석,김진규,김인규,박효국,천기정,김상복 대한방사선 방어학회 1993 방사선방어학회지 Vol.18 No.2

        우라늄 피폭후 효소활성도가 내부피폭의 biomarker로서의 가능성을 연구하기 위하여 수서생물인 잉어9Caprinus carpio)의 복강내 우라늄 투여시 간조직에서 일어나는 여러가지 효소계의 변화를 조사하였다. 이러한 효소활성도의 변화는 우라늄 내부피폭의 biomarker로서 가능성을 가지고 있으며 연구결과는 다음과 같다. 1) 6일째까지 우라늄을 주사하여 적출한 간에서의 전체단백질량은 계속 감소하고 있다. 2) 세포내의 lysosome내에 함유하고 있는 acid protease와 β-glucuronidase의 활성도는 6일째 투여후까지 활성도가 감소하고 있다. 3) Alkaline phosphatase의 경우 6일째 우라늄 투여후까지 증가하고 있으며 반대로 acid phosphatase의 경우 6일째 우라늄 투여후까지 활성도가 급격히 증가하였고 glutamate oxaloacetate transaminase의 활성도는 완만하게 증가하고 있다. 4) Creatine kinase의 활성도는 완만한 감소를 보이고 있으며 malate dehydrogenase는 첫번 우라늄 투여후에 활성도가 급격히 감소하였고 3일째 우라늄 투여후에는 활성도가 거의 나타나지 않았다. We examined various enzyme activity changes by intraperitioneal injection uranium in the carp liver. These enzyme activity changes can be used as biochemical indicators of internal exposure to uranium. The results were followings ; 1) Total protein concentration decreased by intraperitoneal injection in the carp liver. 2) Lysosomal acid protease and β-glucronidase activities increased in the liver until sixth intraperitoneal injection of uranium, but lysosomal acid phosphatase activities decreased in the liver until the sixth injection of uranium. 3) Alkaline phosphatase activities sharply increased and Glutamate oxaloacetate Transaminase activities steadily decreased in the liver until the sixth injection of uranium. 4) Creatine %kinase activities steadily decreased and malate dehydrogenase activities sharply decreased in the liver after the primary injection of uranium. Any malate dehydrogenase activities was not detected after sixth injection of uranium.

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