응고제가 우유두부의 물성 및 관능적 특성에 미치는 영향

우나리야,이민선,박수진,강명화 동아시아식생활학회 2004 동아시아식생활학회지 Vol.14 No.5

Different types of coagulant and characteristics of its concentration added in the process of making milk curd were compared in this study. The pH of whey decreased when the amount of coagulant increased. The turbidity of whey was decreased when 5% of acetic acid and lemon juice were put into as coagulants. The texture of milk curd made with cow's milk and skim milk was measured the highest when acetic acid and lemon juice were added at 3, 5% of their concentration. The fracturability of milk curd made only with cow's milk decreased as the concentration of each coagulant increased. The cohesiveness was decreased as concentration of coagulant increased. The springiness was slightly changed depending on its coagulant but didn't show much of difference. The gummminess of milk curd made with cow's milk was increased when 3, 5% of coagulant was added. The result of sensory evaluation of milk curd showed that preference of milk curd wasn't depending on types of milk nor its coagulant. Also, flavor preference showed better when lemon juice was added. Preference in texture of milk curd was the highest made with cow's milk and skim milk. Preference in taste was high when 10% of lemon juice was added to skim milk and preference in its appearance showed higher when the alum was added as a coagulant to both cow's milk and skim milk than other coagulants.

Changes of Cytosolic $Ca^{2+}$ under Metabolic Inhibition in Isolated Rat Ventricular Myocytes

Kang, Sung-Hyun,Kim, Na-Ri,Joo, Hyun,Youm, Jae-Boum,Park, Won-Sun,Warda, Mohamed,Kim, Hyung-Kyu,Von Cuong, Dang,Kim, Tae-Ho,Kim, Eui-Yong,Han, Jin The Korean Society of Pharmacology 2005 The Korean Journal of Physiology & Pharmacology Vol.9 No.5

To characterize cytosolic $Ca^{2+}$ fluctuations under metabolic inhibition, rat ventricular myocytes were exposed to $200{\mu}M$ 2,4-dinitrophenol (DNP), and mitochondrial $Ca^{2+}$, mitochondrial membrane potential (${\Delta}{\Psi}m$), and cytosolic $Ca^{2+}$ were measured, using Rhod-2 AM, TMRE, and Fluo-4 AM fluorescent dyes, respectively, by Laser Scanning Confocal Microscopy (LSCM). Furthermore, the role of sarcolemmal $Na^+$/$Ca^{2+}$ exchange (NCX) in cytosolic $Ca^{2+}$ efflux was studied in KB-R7943 and $Na^+$-free normal Tyrode's solution (143 mM LiCl ). When DNP was applied to cells loaded with Fluo-4 AM, Fluo-4 AM fluorescence intensity initially increased by $70{\pm}10$% within $70{\pm}10$ s, and later by $400{\pm}200$% at $850{\pm}45$ s. Fluorescence intensity of both Rhod-2 AM and TMRE were initially decreased by DNP, coincident with the initial increase of Fluo-4 AM fluorescence intensity. When sarcoplasmic reticulum (SR) $Ca^{2+}$ was depleted by $1{\mu}M thapsigargin plus $10{\mu}M ryanodine, the initial increase of Fluo-4 AM fluorescence intensity was unaffected, however, the subsequent progressive increase was abolished. KB-R7943 delayed both the first and the second phases of cytosolic $Ca^{2+}$ overload, while $Na^+$-free solution accelerated the second. The above results suggest that: 1) the initial rise in cytosolic $Ca^{2+}$ under DNP results from mitochondrial depolarization; 2) the secondary increase is caused by progressive $Ca^{2+}$ release from SR; 3) NCX plays an important role in transient cytosolic $Ca^{2+}$ shifts under metabolic inhibition with DNP.

Microstructural effect on time-dependent plasticity of nanoporous gold

Kang, Na-Ri,Gwak, Eun-Ji,Jeon, Hansol,Song, Eunji,Kim, Ju-Young Elsevier 2018 International journal of plasticity Vol.109 No.-

<P><B>Abstract</B></P> <P>Annealed, prestrained, and ball-milled nanoporous gold (np-Au) samples were prepared. Since the microstructures of the precursor alloys, such as the crystallographic orientation and grain size, were mostly preserved during the dealloying process, prestrained np-Au is believed to have higher initial dislocation density, and ball-milled np-Au is believed to have higher densities of initial dislocation and grain boundary comparing to annealed np-Au. The time-dependent deformation behavior of np-Au samples with various microstructures was characterized with two parameters; creep strain exponent <I>n</I> and activation volume <SUP> V ∗ </SUP> using spherical nanoindentation creep tests. We found that primary mechanism of time-dependent plasticity for annealed and prestrained np-Au samples is dislocation slip and that for ball-milled np-Au sample is grain boundary sliding. In dislocation slip-dominant time-dependent deformation in np-Au, a higher initial dislocation density lowers <I>n</I> and <SUP> V ∗ </SUP> . In grain boundary sliding-dominant time-dependent deformation in np-Au, the values of <I>n</I> and <SUP> V ∗ </SUP> are similar to those for dislocation slip-dominant time-dependent deformation; however, the creep strain rate in quasi-steady-state is higher than that for dislocation slip-dominant time-dependent deformation.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Three nanoporous gold (np-Au) samples with different microstructure were fabricated. </LI> <LI> Time-dependent plasticity was characterized by spherical nanoindentation creep test. </LI> <LI> Primary mechanism of time-dependent plasticity was found to be dependent on the microstructure of np-Au. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Circular Polyethylene Drape in Prevention of Surgical Site Infection (Cover Trial): Interim Analysis (Nct 03170843)

Ri Na YOO,HyungJin KIM,JaeIm LEE,Won-Kyung KANG,Chang Woo KIM,Sung Uk BAE,Byung Mo KANG,Joong Ho LEE,Rumi SHIN,Byung Kwan PARK,Heung Kwon OH,Han Deok KWAK,Woo Ram KIM,Bong Hyeon KYE 대한외과학회 2019 대한외과학회 학술대회 초록집 Vol.2019 No.10

Bilateral Involvement of Juvenile Temporal Arteritis Associated with Kimura Disease

( Na Ri Kim ),( Churl Hyun Im ),( Jong Wan Kang ),( Ji Hun Kim ),( Tae-in Park ),( Han-ik Bae ),( Eon Jeong Nam ),( Young Mo Kang ) 대한류마티스학회 2018 대한류마티스학회지 Vol.25 No.1

Juvenile temporal arteritis (JTA) is a localized nodular arteritis confined to the temporal artery without evidence of systemic inflammation, and it occurs mainly in patients younger than 50 years. From the first case report, the pathological features of JTA have been suspected to be the morphological equivalent of Kimura disease (KD), which has been supported further by the concurrent cases of JTA with KD. We present the first case of bilateral JTA accompanying KD, which was confirmed by histological and ultrasound evaluations and supports the hypothesis that JTA is a manifestation of KD. The un-excised JTA lesion was resolved completely after corticosteroid therapy with no recurrence. (J Rheum Dis 2018;25:65-68)

The Effect of Community-Based Parent Education Program on Parenting Stress According to Adult Attachment Styles

Na Ri Kang,Do Hoon Kim,Young Sook Kwack 대한소아청소년정신의학회 2019 소아청소년정신의학 Vol.30 No.4

Objectives: The aim of this study was to measure the effect of a group-based parent education program on parenting stress and attitude and comparing the same according to adult attachment styles. Methods: Twenty-two mothers who enrolled in the parent education program participated in our study. The participants filled in the Korean version of the Experience in Close Relationship Revised (ECR-R), Korean-Parenting Stress Index-Short Form (K-PSI-SF), Maternal Behavior Research Instrument (MBRI), and Symptom Checklist-90-Revised (SCL-90-R) before and after the program. We compared the pre - and post-scores of the groups and compared the differences in effect according to adult attachment styles. Results: For all study participants, the Parent Distress (p=0.023) and Total Parenting Stress (p=0.018) significantly declined after the parent education program. There were no differences in other variables. Within the secure attachment group, the Total Parenting Stress (p= 0.008), Parent Distress (p=0.015), and Difficult Child (p=0.011) scores in the K-PSI-SF significantly decreased after participating in the program. The Difficult Child scores (p=0.040) significantly dropped in the K-PSI-SF post program within the secure attachment group, compared to the insecure attachment group. Conclusion: The group-based parent education program impacted parenting stress. Depending on the adult attachment styles, the effect of the program varied.

Temperament and Character Profiles Associated with Internalizing and Externalizing Problems in Children with Attention Deficit Hyperactivity Disorder

Na Ri Kang,Young Sook Kwack 대한신경정신의학회 2019 PSYCHIATRY INVESTIGATION Vol.16 No.3

Objective: This study aimed to identify temperament and character profiles associated with internalizing and externalizing problems in children with attention deficit hyperactivity disorder (ADHD). Methods: Children with ADHD (n=114, 8.51±1.87 years) were selected from the Department of Child and Adolescent Psychiatry at Jeju National University Hospital. They were diagnosed by Kiddie-Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version and evaluated using the Advanced Test of Attention and Korean Wechsler Intelligence Scale for Children-Fourth Edition. Their parents completed the ADHD Rating Scale, Korean-Child Behavioral Checklist, and Junior Temperament and Character Inventory. Results: The participants with both internalizing and externalizing problem had more severe ADHD symptoms and significantly higher novelty seeking, harm avoidance, and self-transcendence, as well as lower self-directedness and cooperativeness than those who had not comorbid problems. Harm avoidance was correlated with their level of internalizing problems regardless of severity of ADHD symptoms. In addition, novelty seeking and sex (male) were being associated with the level of externalizing problems. Conclusion: Differences were observed in the temperament and character profiles of children with ADHD according to their comorbid psychopathology. Results suggested that temperament and character profiles may affect the comorbid psychopathology in children with ADHD regardless of ADHD symptom severity.

Complex repetitive discharge on electromyography as a risk factor for malignancy in idiopathic inflammatory myopathy

( Na Ri Kim ),( Eon Jeong Nam ),( Jong Wan Kang ),( Hyun Seok Song ),( Churl Hyun Im ),( Young Mo Kang ) 대한내과학회 2014 The Korean Journal of Internal Medicine Vol.29 No.6

Background/Aims: We investigated the electromyography (EMG) findings and demographic, clinical, and laboratory features that may predict the development of malignancy in patients with idiopathic inflammatory myopathy (IIM). Methods: In total, 61 patients, 36 with dermatomyositis and 25 with polymyositis, were included. Patients were divided into those with and without malignancies, and comparisons were made between the groups in terms of their demographic, clinical, laboratory, and EMG findings. Results: The frequencies of malignancies associated with dermatomyositis and polymyositis were 22% and 8%, respectively. Patients with malignancies showed a significantly higher incidence of dysphagia (odds ratio [OR], 21.50; 95% confi- dence interval [CI], 3.84 to 120.49), absence of interstitial lung disease (ILD; OR, 0.12; 95% CI, 0.01 to 0.98), and complex repetitive discharge (CRD) on the EMG OR, 26.25; 95% CI, 2.67 to 258.52), versus those without. After adjustment for age, dysphagia and CRD remained significant, while ILD showed a trend for a difference but was not statistically significant. Multivariate analysis revealed that the CRD conferred an OR of 25.99 (95% CI, 1.27 to 531.86) for malignancy. When the frequency of malignancy was analyzed according to the number of risk factors, patients with three risk factors showed a significantly higher incidence of malignancy, versus those with fewer than two (p = 0.014). Conclusions: We demonstrated for the first time that CRD on the EMG was an additional independent risk factor for malignancy in IIM. Further studies on a larger scale are needed to confirm the importance of CRD as a risk factor for malignancy in IIM.

An Update on Mental Health Problems and Cognitive Behavioral Therapy in Pediatric Obesity

Kang, Na Ri,Kwack, Young Sook The Korean Society of Pediatric Gastroenterology 2020 Pediatric gastroenterology, hepatology & nutrition Vol.23 No.1

Prevalence of pediatric obesity has increased worldwide in the last 20 years. Obese children suffer not only physical complications but also mental health problems such as depression, attention deficit hyperactivity disorder (ADHD), and eating disorders, as well as psychosocial impairments, such as school adjustment problems, bullying, and low self-esteem. Recently, there have been some studies on the association of mental health problems and pediatric obesity. In the treatment of pediatric obesity, many previous studies suggest multidisciplinary treatment. However, cognitive behavioral therapy (CBT) has attracted attention because obese children are accompanied by body image distortion, emotion dysregulation, and difficulties in stimulus control. This review is a narrative summary of the recent studies on mental health problems and CBT in pediatric obesity. The relationship between depression/anxiety and pediatric obesity is still inconsistent but recent studies have revealed a bidirectional relation between depression and obesity. Additionally, some studies suggest that obese children may have eating disorder symptoms, like loss of control eating, and require therapeutic intervention for pediatric obesity treatment. Furthermore, impulsivity and inattention of ADHD symptom is thought to increase the risk of obesity. It has also been suggested that CBT can be very effective for mental health problems such as depression, impulsivity, and body image distortion, that may coexist with pediatric obesity, and use of multimedia and application can be useful in CBT.

Intellectual Functioning of Pediatric Patients with Chronic Kidney Disease: Results from the KNOW-Ped CKD

Kang Na Ri,Ahn Yo Han,박유진,Lee Keum Hwa,Baek Hee Sun,Kim Seong Heon,Cho Heeyeon,Cho Min Hyun,Shin Jae Il,Lee Joo Hoon,Cheong Hae Il,Kang Hee Gyung,Park Young Seo,Ha Il-Soo,Moon Duk-Soo,Han Kyoung Hee 대한의학회 2021 Journal of Korean medical science Vol.36 No.20

Background: Chronic kidney disease (CKD) has a negative impact on growth and development in children and is a risk factor for neurocognitive impairment; however, there is limited research on the cognitive function of children and adolescents with CKD. This study therefore aimed to investigate the mean intelligence and risk factors for low intelligence in children and adolescents with CKD. Methods: Eighty-one patients with CKD under 18 years old were included in the KoreaN cohort study for Outcomes in patients With Pediatric Chronic Kidney Disease (KNOW-Ped CKD). Participants completed either the Wechsler Intelligence Scale for Children (6–16 years), or Wechsler Adult Intelligence Scale (> 16 years). Results: The mean full-scale intelligence quotient (IQ) was 91 ± 19; 24.7% of participants scored a full-scale IQ below 80. Participants with a short stature (height Z scores < −1.88), failure to thrive (weight Z scores < −1.65), more severe CKD stage (≥ IIIb), longer duration of CKD (≥ 5 years), and those who were Medicare or Medicaid beneficiaries, had significantly lower mean full-scale IQs. Conclusion: On linear regression analysis, the association between the full-scale IQ, and longer duration of CKD and growth failure, remained significant after controlling for demographic and clinical variables. It is therefore necessary to investigate cognitive impairment in pediatric patients with CKD who exhibit growth failure or for a longer postmorbid period. It is believed that early interventions, such as kidney transplantation, will have a positive effect on IQ in children with CKD, as the disease negatively affects IQ due to poor glomerular filtration rate over time.