동종 골수이식 후 만성 이식편대숙주반응 환자에서 발생한 폐렴구균에 의한 수막뇌염 1예

신완식,김병욱,유진홍,김동집,김춘추,박종원,이종욱,김동욱,강문원,김양리 대한감염학회 1993 감염 Vol.25 No.3

Graft-versus-host disease (GVHD) is a frequent complication after bone marrow transplantation. Infectious complications are common in GVHD patients due to defect in cell-mediated immunity. A rare case of S. pneumoniae meningoencephalitis occured in a patient with extensive form of chronic GVHD after allogeneic bone marrow transplantation. He was immediately treated with full dosage of ceftriaxone and ampicillin. He suffered from various complications such as sepsis, acute renal failure, atelectasis, and seizure. Despite of aggressive treatment, he died probably due to renal shutdown and massive subacute cerebral infarction of left cerebral hemisphere. This report showed two unusual and rare features. First, the infection site was CNS rather than respiratory system. Second, the causative organism was S. pneumoniae, which is rare cause of CNS infection in immunocompromised patients.

단일 전력단 능동 클램프형 고주파 공진 인버터에 관한 연구

강진욱,박재욱,원재선,배영호,김동희 嶺南大學校 工業技術硏究所 2002 工業技術硏究所論文集 Vol.30 No.2

This paper presents active-clamp type high frequency resonant inverter with single-stage. The proposed topology is an integrated circuit of active-clamp type high frequency resonant inverter with boost converters having the function of power factor correction. The input stage of the full-bridge boost rectifier works in discontinuous conduction mode(DCM) with constant duty cycle and variable switching frequency. Hence a high power factor operation is achieved naturally. By adding active-clamp circuit to conventional class-E high frequency inverter, main switch of inverter part operates not only at Zero-Voltage-Switching mode but also reduces the switching voltage stress of main switch. Theoretical analysis in converter part is performed with Psim 4.1 software tool and in inverter part is generally evaluated by using normalized parameter and characteristics values based on characteristics estimation through circuit analysis is given as basis data in design procedure. Also, experimental results are presented to verify theoretical discussion. This proposed inverter can be practically used as a power supply in the fields of induction heating applications, DC-DC converter, etc.

폐경후 여성에서 내피세포 의존성 혈관이완 반응에 에스트로겐의 급성효과 및 엔도쎌린(Endothelin)-1과의 연관성

강진호,김범수,이영욱,금동극,정현욱,이혜숙,이만호,박정로 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.7

천추 전방에서 발생한 신경절 세포종 : 증례 보고 A Case Report

강현구,이승로,박동우,박충기,함창곡,박용욱 한양대학교 의과대학 2002 한양의대 학술지 Vol.22 No.2

We have experienced a case of presacral ganglioneuroma. So, we report a peripheral ganglioneuroma of sacral origin. The patient is 34-year-old man with intermittent low back pain and right sciatica. Myelographic computed tomography revealed extradural lobulated low attenuated tumor lesion within spinal canal at the level of L5 and S1. Tumor indented the thecal sac to the left side, and extended into the pelvic cavity through the intervertebral foramen between S1 and S2. The mass was surgically excised and turned out to be ganglioneuroma pathologically.

직장내 성희롱의 실태에 관한 연구

강동욱 한국비교형사법학회 2001 비교형사법연구 Vol.3 No.2

In this paper I intend to examine various arguments for the origin and meaning of "sexual harassment in the workplace" that is very important social problem. "Sexual harassment in the workplace" in Korea is comprehended as the problem of employment circumstances, and the responsibility of the employer is specially emphasized in related legislations. For these reasons, I interpret it in a broad sense that the rape and forced sexual attack are included in it. And for the study on causes of and countermeasures against "sexual harassment in the workplace" I conducted the statistical research on the actual condition of sexual harassment. The subject of the survey was 500 persons working in region of Young-Dong, but, of these the reply of 259 persons(woman: 237, man: 22) was proved to be effective. I analyzed the reply of 89 persons(woman: 85, man: 4) who answered "have been attacked sexual harassment". Details of this survey are as follows: the type of sexual harassment, particulars of offender, place and time offended, confrontation method of the victim, influence upon the victim, causes of sexual harassment and countermeasures of the victim against sexual harassment etc. On the result of this survey, the ratio of the one who have been attacked sexual harassment is 34.4%, that is very low percentage. Of these, the ratio of irregular workers is higher than that of regular workers. And the ratio of the victim who positively resist the offender is high. I think that these are because of regional characteristics. Besides, the patterns of sexual harassment in region of Young-Dong are generally similar with the nationwide survey results as follows. The ratio of sexual harassment by words is the highest. Mostly it occur only one time, but the severe sexual harassment are committed continuously. Sexual harassment without condition are many. Sexual harassment is regarded as caused by structural problems of our society. The positive confrontation of the victim against the offender is fairly effective for the prevention of sexual harassment.

전방 십자 인대 파열에서의 반월상 연골판 파열의 양상

강충남,김종오,김동욱,고영도,유재두,최창호 대한스포츠의학회 1999 대한스포츠의학회지 Vol.17 No.1

Injury to associated structures is expected to worsen the prognosis of ACL tears. Meniscal injuries are well known to coexist in knees with both acute and chronic ACL injuries. However, it is not conclusive whether the likelihood of encountering a repairable meniscal lesion diminishes as the time from injury increases. W e reviewed records of 127 patient receiving an arthroscopically assisted stabilizing procedure for an acute and chronic ACL injury incurred while skiing, soccer, traffic accident to associated meniscal injury. All patient had undergone arthroscopic evaluation. We classified acute injury as injury less than 3 months old at time of surgery, and chronic injury as more than 3 months old. Acute injuries were 88 cases and chronic injuries were 39 cases. In 55 ski-related injuries, 41 knees were acute and 14 knees were chronic. Fourteen(34%) meniscal tears were noted in chronic cases. In 42 soccer injuries, 20 knees were acute and 22 knees were chronic. In acute cases, 14(70%) meniscal tears were noted and in chronic cases, 14(64%) meniscal tears were noted. In 30 traffic accident injuries, 27 knees were acute and 3 knees were chronic. In acute cases, 19(70%) meniscal tears were noted and in chronic cases, 2(67%) meniscal tears were noted. There was strong trend of the increased incidence of medial involvement in the non-skiers than in the skiers, In the type of meniscal tear with acute ACL rupture, 33 of 52 meniscal were longitudinal tear, 6 were horizontal tear, 4 were radial tear(only in lateral meniscus) and 9 were complex tear. In the pattern of meniscal tear with chronic ACL rupture, 15 of 37 meniscal were longitudinal tear, 3 were horizontal tear, 1 was radial tear(only in lateral meniscus) and 18 were complex tear(medial meniscus 16, lateral meniscus 2). In the treatment of torn menisci, 29 of 52 meniscal tears were treated by conservative treatment and meniscal repair, 21 meniscal tears were treated by partial menisectomy and 2 meniscal tears were treated by subtotal menisectomy in acute injuries. In chronic injury, 10 of 37 meniscal tears were treated by conservative treatment and meniscal repair, 18 meniscal tears were treated by partial menisectomy and 9 meniscal tears were treated by subtotal menisectomy. There was no total menisectomy. As the time from injury increased, the medial meniscus tears were severe and were more likely to require menisectomy.

마이크로 광 조형 기술을 이용하여 미세 유체 시스템을 개발하기 위한 가상 조립 공정의 개발

강현욱,이인환,조동우 한국공작기계학회 2004 한국공작기계학회 춘계학술대회논문집 Vol.2004 No.-

As it is difficult to construct a micro-fluidic system composed of micro-mixers, micro-channels and/or micro-chambers in a single process, an assembly process is typically used. The assembling and bonding of micro-parts, however, introduces other problems. In this work, a virtual assembly process was developed that can be used to design various micro-fluidic systems before actual fabrication commences. In the process, the information required for the micro-stereolithography process is generated automatically. Consequently, complex micro-fluidic systems can be fabricated in a single process, thereby avoiding the need for additional assembly or bonding processes. Using the developed process, several examples were fabricated.

제왕절개술을 위한 척추마취 시 국소마취제 주입 속도가 저혈압에 미치는 영향

강용인,방은치,신동욱,권대은,김수연,이현숙,조경숙,이수연 이화여자대학교 의과학연구소 2012 EMJ (Ewha medical journal) Vol.35 No.2

Objectives: Maternal hypotension is a common problem during cesarean section under spinal anesthesia. We evaluated the influence of injection speed of local anesthetic to subarachnoid space on maternal hypotension and level of sensory block. Methods: Bupivacaine (0.5%) 9 mg with fentanyl 10 μg was injected to subarachnoid space either quickly (during 20 seconds, 0.1 mL/sec, n=20) or slowly (during 100 seconds, 0.02 mL/sec, n=20) in parturients scheduled for elective cesarean section. The onset and level of sensory block was checked and heart rate and blood pressure was checked by 2.5 minutes during 20 minutes. Hypotension (systolic blood pressure <100 mmHg or <70% of baseline) was treated with ephedrine. Results: Hypotension occurred 70% of parturients with spinal anesthesia. Slow injection didn’t influence on the onset and level of sensory block and didn’t reduce the incidence of hypotension. But onset of hypotension was delayed. Conclusion: Slow injection (during 100 seconds, 0.02 mL/sec) of local anesthetic delayed onset of hypotension and required less amount of ephedrine. Slow injection of local anesthetic was one of the effective methods for the cardiovascular stability during cesarean section under spinal anesthesia.

천측두 동맥류 1예

강성호,임대준,김동욱,김보형 건국대학교 의과학연구소 1998 건국의과학학술지 Vol.8 No.-

Superficial temporal artery aneurysm is a rare entity, which is related to blunt trauma. It was diagnosed with history, physical examination and CT or angiography. Aneurysm is simply treated with excision and ligation. We report a case with review of literature.

갑상선 유두상 암종과 유두상 증식에 대한 S-100 단백 및 EMA 발현에 대한 연구

강대영,김경희,최정목,송규상,강동욱 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.2

The diagnosis of papillary carcinoma of the thyroid is readily achieved based on a defined aggregate of histopathologic features. A papillary architecture is an imporant but not pivotal component of the diagnosis. The classic nuclear features are the essential diagnostic element. However, both papillary architecture and nuclear features may be encountered in other conditions and produce problems in histopahologic interpretation. A papillary architecture may be found within a follicular or an oncocytic neoplasm of within the nodules of hyperplastic nodular goiter. Moreover, there may be scattered cells within several thyroid lesions that display some of the nuclear characteristics of papillary carcinoma. The distinction of these lesions from papillary carcinoma is important for differential diagnosis. Thus, the availability of supportive diagnosic evidence would be helpful. Immunoreactivity for S-100 and epithelial membrace antigen was investigated in 16 papillary thyroid carcinomas(PTC), including three examples of the follicular variant, 16 cases of papillary hyperplasis, 8 follicular adenomas, and 6 follicular carcinomas. The degree of reaction was rated on a four point scale: +++, most cells(>51%) have positive staining; ++, 11-50% of cells have positive staining; +, less than 10% of cells have positive staining; -, no positive staining is present. The results are summarized as follows: 1) All the papillary carcinomas showed intense nuclear and cytoplasmic expression of S-100 (+++; 7 cases, ++; 9 cases), and EMA was expressed(++; 7 cases, ++; 6 cases, +; 3 cases). 2) In the cases of papillary hperplasia, papillary foci were generally negative for S-100 and EMA(12/16 ; -). In some areas, they were focal, of weak intensity, and showed preferential apical cytoplasmic location of oncocytic change. 3) Four of eight follicular adenomas expressed S-100(++;2 cases, +; 2 cases), whereas four were completely negative. EMA was also expressed(++; 2 cases, +; 3 cases). 4) Follicular carcinoma showed variable expression of S100 and EMA Five of six follicular carcinomas expressed S-100(++; 2 cases, +; 3 cases), whereas one was negative. EMA was also expressed(++; 2 cases, +; 1 case). In conclusion, in the distinction of papilary carcinoma from papillary hyperplasia, we would recommend an initial histological appraisal, with immunohistochemical staining of S100 and EMA in difficult cases.