Levels of Biogenic Amines in Cheeses and Their Impact on Biochemical and Histological Parameters in Rats

Kahled M. El-Zahar,Ahmed M. Abd El-Zaher,Mohamed Fawzy Ramadan 한국응용생명화학회 2014 Applied Biological Chemistry (Appl Biol Chem) Vol.57 No.1

Composition of amino acids and biogenic amines(BA) in different cheeses (Ras, Blue and Mish) were estimated. The amino acids content of Ras cheese after 6 and 24 months ofripening were 33.1 and 26.6 mg/g, respectively. In Blue cheese,after 6 and 12 months ripening, the levels ranged from 29.2 to25.5 mg/g, whereas in Mish cheese the levels were 33.9 and 30.0mg/g, respectively. The concentrations of cadaverine andtryptamine were similar in the Mish and Ras cheeses. Level ofphenylethylamine accumulation was relatively similar in Ras andBlue cheeses, whereas levels of histamine and tryptamine werehigh in Ras cheese, reaching 260 and 200 mg/kg, respectively. The toxicological effects of specific BA on liver and kidneyfunctions, as well as biochemical parameters in rats were assayed. The type and the concentration of BA accumulation in cheesesaffected the functions of liver and kidney in rats treated with BA. Rats treated with 1 mg amines showed difference in total proteinsand albumin during the experimental period except after 6 days,wherein no difference in albumin was noted. In addition,treatment with 2 mg amines showed significant decreased in totalproteins and albumin during the testing period, except after 2, 4,and 6 days, wherein no changes in total proteins and albuminlevels were detected. The highest concentration of amines (3 mg/kg/daily) showed decrease in total proteins and albumin after 2, 8,and 10 days. Histological examination revealed that organs weremoderately affected by direct injection of BA as compared withorgans from control groups. Liver marked vascular congestionwith abnormal double central vein occurances leading to fibrosis,whereas in the kidney, thickened vascular spaces were observed.

Comprehensive Analysis of Alternative Splicing Across Tumors from 8, 705 Patients

Kahles, André,Lehmann, Kjong-Van,Toussaint, Nora C.,Hü,ser, Matthias,Stark, Stefan G.,Sachsenberg, Timo,Stegle, Oliver,Kohlbacher, Oliver,Sander, Chris,Rä,tsch, Gunnar Elsevier Science B.V., Amsterdam 2018 Cancer cell Vol.34 No.2

MODELS TO EVALUATE MARKET DISCONTINUITIES SUCH AS ONES GENERATED BY THE WEB

Kahle, Lynn R.,Duncan, Marc 계명대학교 산업경영연구소 2000 ASIAN JOURNAL OF BUSINESS AND ENTREPRENEURSHIP Vol.3 No.-

The concept of strategic planning and its presumed value to business in the form of performance and increased profits is a cornerstone of academic pedagogy. Numerous methods or "tools" to assist firms in their planning efforts have been developed, such as the SWOT analysis and Central Driving Forces. Perhaps the best-known tool for analyzing entrepreneurial opportunities by industry is Porter's Five Forces. Although the value of these tools is irrefutable in the broadest of contexts, the derived conclusions sometimes are misplaced, even suggesting an incorrect analysis of a seemingly valuable opportunity or incorrectly underestimating looming new risks, particularly in times of market discontinuities. This article considers this issue. It looks at the many market discontinuities created by the Internet, considers them in the context of traditional means to evaluate them, and offers how these traditional tools might be expanded to bring them into confluence with this new medium as well as other yet unforeseen market discontinuities.

Levels of Biogenic Amines in Cheeses and Their Impact on Biochemical and Histological Parameters in Rats

El-Zahar, Kahled M.,Abd El-Zaher, Ahmed M.,Ramadan, Mohamed Fawzy The Korean Society for Applied Biological Chemistr 2014 Applied Biological Chemistry (Appl Biol Chem) Vol.57 No.1

Composition of amino acids and biogenic amines (BA) in different cheeses (Ras, Blue and Mish) were estimated. The amino acids content of Ras cheese after 6 and 24 months of ripening were 33.1 and 26.6 mg/g, respectively. In Blue cheese, after 6 and 12 months ripening, the levels ranged from 29.2 to 25.5 mg/g, whereas in Mish cheese the levels were 33.9 and 30.0 mg/g, respectively. The concentrations of cadaverine and tryptamine were similar in the Mish and Ras cheeses. Level of phenylethylamine accumulation was relatively similar in Ras and Blue cheeses, whereas levels of histamine and tryptamine were high in Ras cheese, reaching 260 and 200 mg/kg, respectively. The toxicological effects of specific BA on liver and kidney functions, as well as biochemical parameters in rats were assayed. The type and the concentration of BA accumulation in cheeses affected the functions of liver and kidney in rats treated with BA. Rats treated with 1 mg amines showed difference in total proteins and albumin during the experimental period except after 6 days, wherein no difference in albumin was noted. In addition, treatment with 2 mg amines showed significant decreased in total proteins and albumin during the testing period, except after 2, 4, and 6 days, wherein no changes in total proteins and albumin levels were detected. The highest concentration of amines (3 mg/kg/daily) showed decrease in total proteins and albumin after 2, 8, and 10 days. Histological examination revealed that organs were moderately affected by direct injection of BA as compared with organs from control groups. Liver marked vascular congestion with abnormal double central vein occurances leading to fibrosis, whereas in the kidney, thickened vascular spaces were observed.

Firefighter daytime visibility: trim properties and conspicuity

Jonathan T. Kahl,Nathan J. Anderson,Glenn Casner,Vera Shuman,Tim J. Gardner 한국의류학회 2019 Fashion and Textiles Vol.6 No.1

Conspicuity enhancing trims on turnout gear promote firefighters’ abilities to (1) reduce the possibility of struck-by accidents, (2) be located and recognized by others, and (3) coordinate their work with colleagues. Firefighting personal protective equipment (PPE) ensemble standards specify technical requirements for new visibility materials. A better understanding of the relation between laboratory measures of material properties and behavioral measures of conspicuity can be used to evaluate existing and newly developed turnout gear trim designs. The current paper examined how photometric luminance measures (%Y) of fluorescent trims on firefighter turnout gear relate to daytime conspicuity in two naturalistic field experiments (distance detection and identification, peripheral detection). The test samples consisted of lime yellow and orange-red fluorescent trims, including traditional solid trims and more recently developed segmented trims. We found overall strong relations between measured luminance and (1) observers’ detection of a firefighter from afar, and (2) observers’ identification of the color of a firefighter’s clothing in their peripheral view. A relation did not exist between %Y and peripheral detection. Additionally, the experiments demonstrated that traditional solid and newer segmented trim designs showed little conspicuity performance difference, with the only observed difference being in peripheral color identification. This suggests that the impact of luminance on conspicuity may be overestimated when evaluating a trim’s daytime performance. Our results further support that luminance measures alone are not sufficient to evaluate the conspicuity of turnout gear in naturalistic settings.

Study on α-cluster levels in non-4n nuclei using low-energy RI beams

Yamaguchi, H,Kahl, D,Hayakawa, S,Sakaguchi, Y,Abe, K,Nakao, T,Suhara, T,Iwasa, N,Kim, A,Kim, D H,Cha, S M,Kwag, M S,Lee, J H,Lee, E J,Chae, K Y,Wakabayashi, Y,Imai, N,Kitamura, N,Lee, P,Moon, J Y,Lee, IOP Publishing 2017 Journal of physics. Conference series Vol.863 No.-

Born International:Exporting From Day One as an Alternative to Traditional Internationalization

Shoham, Aviv,Kahle, Lynn R.,Rose, Gregory M. Research Institute for Business and Entrepreneursh 1998 ASIAN JOURNAL OF BUSINESS AND ENTREPRENEURSHIP Vol.1 No.-

Cavusgil (1994) observed that a new breed of international firms has emerged. They differ from other firms in business orientation. They are born international and do not follow the traditional internationalization process. Rennie's study (1993) sampled such firms (in Australia) and provided descriptive characteristics of "Born International Firms" (BIF). This study provides information about such firms in Israel. Best viewed as an exploratory study, it replicates Rennie's findings and provides preliminary support to the generalizability of his findings. By providing descriptive information on additional constructs, this study also extends Rennie's study. We find a number of differences for firms that follow the two business orientations in marketing variables and in performance. In the introduction, we noted that Cavusgil (1994, 1995) observed that a new type of international firms has emerged. They differ from other firms by being BIF. Thus, they do not follow the traditional internationalization process model. Previously, Rennie (1993) studied such firms in Australia. He provided descriptive characteristics of BIF. While Rennie (1993) provided a necessary first step in the study of such firms, there is a need for additional studies about this new phenomenon. Our study provides additional information about BIF in an Asian country, Israel. As noted, our study served two main purposes. First, it explores some of Rennie's findings (1993) in Israel. We provide preliminary support to the generalizability of some of Rennie's findings. Similar to his findings, we find that the phenomenon is widespread and not typical to Australian exporters only. We also find that Israeli BFI, like their Australian counterparts, outperform frims that follow the traditional internationalization process. However, contrary to Rennie (1993), Israeli BFI tend to emphasize high quality (as in Australia), but couple this increased quality with higher prices. While being exploratory in nature, the differences observed on pricing strategy in this study have important preliminary managerial implications. Given that increased quality was coupled with high prices in Israel, aspiring entrepreneurs have two strategic options. They can either use low prices, especially during market penetration. Alternatively, they can pursue a premium strategy, charging higher prices for the enhanced quality of their products. Additionally, our study provided data on constructs that were not addressed by Rennie (1993). Thus, the study extended Rennie's findings (1993) beyond the differences observed in Australia. Obviously, as noted in the "Limitations" and "Discussion" sections, much work still remains. This phenomenon is extremely important as evidenced by the fact that 25 percent of the firms in our sample identified themselves as BIF. The route to internationalization differs for BIF and further research is called for to enhance our understanding of such firms.

Experimental investigation of a linear-chain structure in the nucleus ¹⁴C

Yamaguchi, H.,Kahl, D.,Hayakawa, S.,Sakaguchi, Y.,Abe, K.,Nakao, T.,Suhara, T.,Iwasa, N.,Kim, A.,Kim, D.H.,Cha, S.M.,Kwag, M.S.,Lee, J.H.,Lee, E.J.,Chae, K.Y.,Wakabayashi, Y.,Imai, N.,Kitamura, N.,Lee North-Holland Pub. Co 2017 Physics letters. Section B Vol.766 No.-

It is a well-known fact that a cluster of nucleons can be formed in the interior of an atomic nucleus, and such clusters may occupy molecular-like orbitals, showing characteristics similar to normal molecules consisting of atoms. Chemical molecules having a linear alignment are commonly seen in nature, such as carbon dioxide. A similar linear alignment of the nuclear clusters, referred to as linear-chain cluster state (LCCS), has been studied since the 1950s, however, up to now there is no clear experimental evidence demonstrating the existence of such a state. Recently, it was proposed that an excess of neutrons may offer just such a stabilizing mechanism, revitalizing interest in the nuclear LCCS, specifically with predictions for their emergence in neutron-rich carbon isotopes. Here we present the experimental observation of α-cluster states in the radioactive <SUP>14</SUP>C nucleus. Using the Be10+α resonant scattering method with a radioactive beam, we observed a series of levels which completely agree with theoretically predicted levels having an explicit linear-chain cluster configuration. We regard this as the first strong indication of the linear-chain clustered nucleus.

The phoropter method: a stochastic graphical procedure for prior elicitation in univariate data models

Casement Christopher J.,Kahle David J. 한국통계학회 2023 Journal of the Korean Statistical Society Vol.52 No.1

Common methods for Bayesian prior elicitation call for expert belief in the form of numerical summaries. However, certain challenges remain with such strategies. Drawing on recent advances made in graphical inference, we propose an interactive method and tool for prior elicitation in which experts express their belief through a sequence of selections between pairs of graphics, reminiscent of the common procedure used during eye examinations. The graphics are based on synthetic datasets generated from underlying prior models with carefully chosen parameters, instead of the parameters themselves. At each step of the process, the expert is presented with two familiar graphics based on these datasets, billed as hypothetical future datasets, and makes a selection regarding their relative likelihood. Underneath, the parameters that are used to generate the datasets are generated in a way that mimics the Metropolis algorithm, with the experts’ responses forming transition probabilities. Using the general method, we develop procedures for data models used regularly in practice: Bernoulli, Poisson, and Normal, though it extends to additional univariate data models as well. A free, open-source Shiny application designed for these procedures is also available online, helping promote best practice recommendations in myriad ways. The method is supported by simulation.

Bilateral comparison od medium vacuum standards between PTB and KRISS

Seung-Soo Hong+,Kahl Jousten,Kwang-Hwa Chung,Yong-Hyeon Shin 한국물리학회 2004 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.44 No.6

A bilateral comparison of medium-vacuum standards at Physikalisch-Technische Bundesanstalt (PTB) in Germany and the Korea Research Institute of Standards and Science (KRISS) in Korea was performed in the pressure range from 3 Pa to 100 Pa in 2002. In this comparison, we used two absolute-type capacitance diaphragm gauges as transfer standards. The dierence between the data obtained at KRISS and those obtained at PTB was less than the combined standard uncertainty (k = 2) for the two standards.