충수염의 임상적 고찰과 초음파의 유용성

박정배,양혁준,김형수,황성연,박철완,이근 대한응급의학회 1995 대한응급의학회지 Vol.6 No.2

Appendicitis is the most common acute abdomen in Emergency Medical Center & outpatient department. But sometimes, it is difficult for us to diagnose because of clinically variable symptoms. We reviewed the ultrasonographic findings and analyse 521 cases of appendectomy patients about its distribution of sex and age, seasonal prevalence, clinical symptom and signs, laboratory findings, duration from onset of symptom to arrival at hospital, duration from arrival at hospital to operation, vital signs, operative results, and associated diseases, which were treated at the department of General Surgery & Emergency Medical Center in Chung Ang Gil Hospital from July, 1994 to June, 1995. The results were as follows : 1. The most common age group was second decade. And male to female ratio was 1.43:1. Seasonal variation was not significant. 2. Of 521 cases, 141 cases(27.1%) visited the hospital within 24 hours from the onset of symptom, and 259 cases(49.7%) visited between 24 to 48 hours. 3. In duration from arrival to operation, the cases within 6 hours were 263 (50.5%), the cases between 6 and 12 hours were 131(25..1%). 4. In systolic blood pressure, cases below 90mmHg were 19(3.6%), cases above 160mmHg were 23(4.4%). Below 60mmHg diastolic pressure were 55 cases(10.6%), cases above 110mmHg were 9(1.7%). In pulse rate, above 90 rate/min were 171(32.8%). 5. On admission leukocytosis was found in 413 cases(79.3%) and 342 cases of them were pathologic appendicitis. 6. Ultrasoundgraphy was performed in the 87 cases, but 23 cases were suggested appendicitis. Among 23 cases, 22(95.7%) revealed pathologic appendicitis at ooperation and labortatory examination. Of the 64 cases which were normal on ultrasonography, only 2 cases(3.1%) were proved to be appendicitis. 7. The results of 496 operations without ultrasonography were appendicitis in 390 cases(78.6%), mesenteric lymphadenopathy 36(7.3%), pelvic inflammatory disease 28(5.6%), fecalith 15(3.0%), terminal ileitis 8(1.6%), diverticulitis 7(1.4%), urinary tract stones 5(1.0%), cecal cancer 2 cases, right ovarian tumor 2 cases, tubo-ovarian abscess 2 cases, grater omentum internal hernia 1 case. Our results showed that the sensitivity of ultrasonohraphy was 95.8% and the specificity 98.4% in the diagnosis of appendicitis, It suggests that the ultrasonography is very helpful in the diagnosis & differential diagnosis of acute appeendiditis.

마우스에서 자외선조사에 의한 피부주름형성에 대한 생약추출물의 억제효과

구성근, 배부희, 허진주, 미가, 강봉수, 김준형, 남상윤, 윤영원, 김종수, 이범준 충북대학교 동물의학연구소 2008 Journal of Biomedical and Translational Research Vol.9 No.3

본문참고

의약정보담당자(MR)의 기능 및 역할에 관한 연구

이동일,제해관,윤석준,안형식,문영배 한국의료QA학회 2003 한국의료질향상학회지 Vol.10 No.1

Background : Aim of this study is focused on the analysis of the needed abilities of medical representatives resulting in building up the market and increasing sales. It is to propose methods to increase this ability ensuring continuous growth in market share and profit. Methods : A survey was conducted between January 6 and May 31, 2003. Using SPSS(Version 10.0), the collected data was analyzed by Hotelling T2, factor analysis. Some hypotheses were selected to include the conclusion. Some questionnaires for physicians working in hospitals or clinics and the medical representatives working in a pharmaceutical company were created and asked to them to either prove or reject those hypotheses. The results were analyzed to find the primary factors that effect the interactions between physician and the medical representatives. These factors were also studied along with the theoretical research based on published references. Results : The results were as follows. The main reasons for the physician to meet with a medical representatives were collection of product informations needed for patient treatment and collection of informations on current medical issue and as well as personal interests. The main parameters by which physicians evaluate the medical representatives are human relationship including sincerity and manners and supply of accurate and unbiased information on products. Overall, the medical representatives’ perception on the importance of medical knowledge and ability to deliver it are lower than that expected by physicians. Conclusion : Medical and pharmaceutical companies’ environment are changed rapidly. And those changes forced medical representatives to set new roles and competency. In order to drive away from the past ‘rule of thumb’ and ‘adaptation to circumstance’, optimal method and systemic development to train and support the medical representatives should be quipped. They will help ,medical representatives to be specialists in medical knowledge and to understand the exact need of health care professions. Product competitiveness will be increased and eventually successful business can be achieved through it.

횡적 부조화 및 전치부 개방교합을 동반한 골격성 II급 부정교합 환자의 치험례

Jun-Hyeong Bae(Jun-Hyeong Bae),Sung-Hwan Choi(Sung-Hwan Choi),Hyung-Seog Yu(Hyung-Seog Yu) 연세대학교 치과대학 두개안면기형연구소 2023 연세임상교정 Vol.30 No.1

목적: 골격성 II급 경향과 함께 횡적 부조화 및 전치부 개방교합을 가진 장안모 환자에 대해 비수술적인 방법, 즉, 상악궁의 급속 확장과 상악 구치부의 압하, 상·하악 전치열의 후방이동을 시행한 증례를 보고하고자 한다. 증례: 본 27세 여환은 전치부 개방교합을 주소로 본원에 내원하였으며, 그 이외에도 골격성 II급 및 상·하악골 횡적 부조화 경향을 보였다. 먼저 횡적 부조화 해소를 위해 Miniscrew-assisted Rapid Palatal Expansion (MARPE)를 이용한 급속확장을 시행하였으며, 골격성 고정원으로 상악 구치부를 압하하여 하악골의 전상방 회전(autorotation)과 함께 전치부 개방교합을 해소하고자 했고, 마지막으로 상·하악 전치열의 후방이동을 통해 추가적인 수직피개를 확보하고자 했다. 그 결과, 하악골의 성공적인 전상방 회전으로 인해 전후방적, 수직적 골격관계의 개선과 함께 입술폐쇄부전과 근육의 긴장이 해소되었다. 결론: 장안모, 골격성 II급, 전치부 개방교합을 동반한 환자에서 골격성 고정원을 이용하여 상악 구치부의 합입과 함께 하악 구치부의 정출을 방지하면 성공적으로 하악골의 autoration을 유도할 수 있다. 상·하악 치열 전체의 저항중심을 고려하여 후방이동을 시행하면 교합평면의 회전으로 수직피개를 증가시킬 수 있다. Purpose: We report the case of a skeletal Class II hyperdivergent patient with an anterior open bite and maxillomandibular transverse discrepancy who underwent orthodontic treatment with maxillary expansion, maxillary molar intrusion, and total distalization of the maxillary and mandibular teeth. Case report: A 27-year-old patient came to our clinic for the treatment of an anterior open bite. She also had a Class II malocclusion with a transverse discrepancy. For the transverse discrepancy, rapid maxillary expansion was performed using Miniscrew-assisted Rapid Palatal Expansion (MARPE). Then, we used temporary anchorage devices (TADs) to intrude the maxillary molars, which can cause upward and forward autorotation of the mandible and closure of the anterior open bite. Finally, total distalization of both the maxillary and mandibular teeth was performed to further increase the overbite. Successful autorotation of the mandible resulted in the improvement of the sagittal and vertical skeletal relationships and the alleviation of muscle tension and lip incompetency. Conclusion: In patients with a hyperdivergent profile, Class II malocclusion, and anterior open bite, successful autorotation of the mandible can be induced using TADs to intrude the maxillary molars and prevent extrusion of the mandibular molars. Total distalization of the maxillary and mandibular teeth, with consideration of the center of resistance, can increase overbite by rotating the occlusal plane.

Antioxidative Activity of the Hydrolytic Enzyme Treated Sorbus commixta Hedl. and its Inhibitory Effect on Matrix Metalloproteinase-1 in UV Irradiated Human Dermal Fibroblasts

Bae, Jun-Tae,Sim, Gwan-Sub,Kim, Jin-Hwa,Pyo, Hyeong-Bae,Yun, Jong-Won,Lee, Bum-Chun 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.9

Superoxide radical scavenging activity and DPPH radical scavenging activity were assessed in order to evaluate the antioxidant effect of the Sorbus commixta Hedl. extract (SCoE). SCoE was also treated with several carbohydrate-hydrolytic enzymes that significantly increased the total phenol and flavonoid composition of SCoE. The enzymatically treated SCoE was then assessed for antioxidative activity. The most efficient radical scavenging activity was observed when SCoE was treated with -glucanase. The radical scavenging activity of ${\beta}-glucanase-treated$ SCoE (${\beta}-GSCoE$) enhanced the viability of human dermal fibroblasts (HDFs) exposed to ultraviolet (UV) light. The intracellular reactive oxygen species (ROS) scavenging activity of ${\beta}-GSCoE$ was assessed using UVB (20 $mJ/cm^2$)-irradiated HDFs. UVB irradiation increased dichlorofluorescein (DCF) fluorescence, which was measured by a 5-(6-)chloromethyl-2',7'-dichlorodihydrofluorescein diacetate ($CM-H_2DCFDA$). DCF-fluorescence was significantly decreased in the ${\beta}-GSCoE-containing$ culture medium, suggesting that ${\beta}-GSCoE$ scavenges free radicals. The protective effect was further verified by assessing the expression of matrix metalloproteinase-1 (MMP-1) in UVA-irradiated HDFs. The treatment of UVA-irradiated HDFs with ${\beta}-GSCoE$ resulted in a dose-dependent decrease in the expression level of MMP-1 protein and mRNA. These results suggest that ${\beta}-GSCoE$ may mitigate the effects of photoaging in skin by reducing UV-induced adverse skin reactions.

Pharmacokinetics of SH003 which is a candidate for new anticancer agent in rat

Hyeong Jun Kim,In Sook Kim,Min Sun Choi,Hyun Kim,Young Seok Ji,So Young Yoon,Ki Beum Kim,In Yong Bae,Ko Sung Kyu,Hye Hyun Yoo 한국분석과학회 2016 학술대회논문집 Vol.2016 No.11

PRESSURE REPRESENTATION WITH SLIP BOUNDARY CONDITION

Hyeong-Ohk BAE,Hi Jun CHOE,Bum Ja JIN 한국산업응용수학회 2005 한국산업응용수학회 학술대회 논문집 Vol.- No.-

We first represent the pressure in terms of the velocity in ?³?. Using this representation we prove that a solution to the Navier-Stokes equations is in L<SUP>∞</SUP>(?³?×(0, ∞)) under the critical assumption that u ∈ L<SUP>r,r′</SUP>loc, 3/r+2/r′ ≤ 1 with r ≥ 3. In [4], a boundary L<SUP>∞</SUP> estimate for the solution is derived if the pressure on the boundary is bounded. In our work, we remove the bounded ness assumption of the pressure. Here, our estimate is local. Indeed, employing Moser type iteration and the reverse Holder inequality, we find an integral estimate for L<SUP>∞</SUP>-norm of u.

Effect of Bi-/Unilateral Masticatory Training on Memory and Concentration - Assessor-blind, Cross-over, Randomized Controlled Clinical Trial

Jun-hyeong Bae,Hyungsuk Kim,Do Young Kang,Hyeji Kim,Jongyeon Kim,Koh-Woon Kim,Jae-Heung Cho,Mi-yeon Song,Won-Seok Chung 대한한의학회 2022 대한한의학회지 Vol.43 No.2

ON THE GENERALIZED HYERS-ULAM-RASSIAS STABILITY OF A QUADRATIC FUNCTIONAL EQUATION

Bae, Jae-Hyeong,Jun, Kil-Woung Korean Mathematical Society 2001 대한수학회보 Vol.38 No.2

In this paper, we investigate the generalized Hyers-Ulam-Rassias stability of a quadratic function equation f(x+y+z)+f(x-y)+f(y-z)+f(z-x)=3f(x)+3f(y)+3f(z) and prove the Hyers-Ulam-Rassias stability of the equation on bounded domain.

A Regularity Criterion for the Navier-Stokes Equations

Bae, Hyeong-Ohk,Choe, Hi Jun Marcel Dekker, Inc 2007 Communications in partial differential equations Vol.32 No.7

<P> We prove that a weak solution u = (u1, u2, u3) to the Navier-Stokes equations is strong, if any two components of u satisfy Prodi-Ohyama-Serrin's criterion. As a local regularity criterion, we prove u is bounded locally if any two components of the velocity lie in L6, ∞.</P>