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Ju, Jiwon,Kim, Kangmin,Lee, Kui-Jae,Lee, Wang Hu,Ju, Ho-Jong The Korean Society of Plant Pathology 2017 Plant Pathology Journal Vol.33 No.1
Barley yellow dwarf virus (BYDV) belongs to Luteovirus and is limited only at phloem related tissues. An open reading frame (ORF) 4 of BYDV codes for the movement protein (MP) of BYDV gating plasmodesmata (PD) to facilitate virus movement. Like other Luteoviruses, ORF 4 of BYDV is embedded in the ORF3 but expressed from the different reading frame in leaky scanning manner. Although MP is a very important protein for systemic infection of BYDV, there was a little information. In this study, MP was characterized in terms of subcellular localization and programmed cell death (PCD). Gene of MP or its mutant (ΔMP) was expressed by Agroinfiltration method. MP was clearly localized at the nucleus and the PD, but ΔMP which was deleted distal N-terminus of MP showed no localization to PD exhibited the different target with original MP. In addition to PD localization, MP appeared associated with small granules in cytoplasm whereas ΔMP did not. MP associated with PD and small granules induced PCD, but ΔMP showed no association with PD and small granules did not exhibit PCD. Based on this study, the distal N-terminal region within MP is seemingly responsible for the localization of PD and the induction small granules and PCD induction. These results suggest that subcellular localization of BYDV MP may modulate the PCD in Nicotiana benthamiana.
Perfect Manipulation of Open Stochastic Quantum Systems with Imperfect Detection
Ju-Ju Hu,Qiang Ke,Ying-Hua Ji 제어·로봇·시스템학회 2022 International Journal of Control, Automation, and Vol.20 No.3
Utilizing the homodyne-based feedback control, this paper studies the influence of quantum detection efficiency on the state transfer control of open quantum systems. Under steady state, we give the relations between the feedback control coefficient, detection efficiency and measurement strength. On this basis, we investigate the state transfer under three typical categories of noise: depolarizing channel, amplitude damping channel and phase damping channel in detail. Moreover, we proposed the control strategy which can completely manipulate the stochastic quantum system from an arbitrary initial state to the target eigenstate with fast convergence for the lower or larger detection efficiency in the absence of additional control. We also find that the state transfer of the system can be realized by no-knowledge quantum feedback. Numerical simulation experiments further verify the control scheme can be extended to multi-quantum bit systems.
Clinical analysis and review of literature on pilomatrixoma in pediatric patients
Hu, Ju Long,Yoo, Hyokyung,Kwon, Sung Tack,Kim, Sukwha,Chung, Jee Hyeok,Kim, Hyeonwoo,Kim, Jinhyun,Yu, Na Hee,Kim, Byung Jun Korean Cleft Palate-Craniofacial Association 2020 Archives of Craniofacial Surgery Vol.21 No.5
Background: Pilomatrixoma is a benign tumor that originates from the hair follicle matrix. It usually presents as a hard, slow growing, solitary mass that can be easily misdiagnosed as other skin masses. The aim of this study was to clinically analyze a case series of pilomatrixoma in pediatric patients from Korea. Methods: A total of 165 pediatric patients from 2011 to 2018 with a histological diagnosis of pilomatrixoma were included. A retrospective review was performed using the electronic medical records, including patient demographics, number and location of the mass, clinical and imaging presentation, and postoperative outcomes. Results: There were 61 male and 104 female patients with 152 solitary and 13 multiple pilomatrixomas. Among solitary pilomatrixomas, the lesion commonly occurred in the head and neck (84.2%), followed by upper limbs (11.2%), lower limbs (3.3%), and trunk (1.3%). The pilomatrixoma lesion presented as the following types based on our clinical classification: mass (56.02%), pigmentation (25.31%), mixed (12.65%), ulceration (4.82%), and keloid-like (1.2%). Ultrasonography showed a high positive predictive value (95.56%). There were no specific complications observed except for two cases of recurrence. Conclusion: Pilomatrixoma has various clinical feature presentations and commonly occurs in the head and neck. Ultrasonography is a helpful diagnostic tool. Surgical removal of the lesion is the main treatment method with a low recurrence rate.
Inhibitory Effects of Chicken Egg Yolk Antibody on Infection of Escherichia coli in Macrophage
Jin-Ju Lee,Dong-Hyeok Kim,Jeong-Ju Lim,Dae-Geun Kim,Gon-Sup Kim,Won-Gi Min,Hu-Jang Lee,Man-Hee Rhee,Hong-Hee Chang,Suk Kim 경상대학교 농업생명과학연구원 2012 농업생명과학연구 Vol.46 No.2
The present study evaluated the potential use of immunoglobulin prepared from egg yolk of chickens immunized with Escherichia coli K88 (IgY-Ec) in the control of E. coli K88 infection in RAW 264.7 murine macrophage. The binding activity of IgY-Ec against E. coli K88 surface protein was more specific and increased than control IgY. In infection assay of E. coli in macrophage, the specific IgY-Ec to E. coli K88 remarkably inhibited the phagocytic activity comparing to nonspecific IgY (p<0.001). In adherence assay, bacterial adhesion on macrophage cells was definitely reduced by preincubation of IgY-Ec compared with nonspecific IgY (p<0.05). These findings suggested that IgY-Ec have the protective effects against pathogens and IgY-based diets may have potential benefits for preventing or treating various infections in domestic animals.