한국 불교미술에 대한 심미적 태도 향상을 위한 총체적아동미술 프로그램 개발 연구

이수경,이주연 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

Ancient Korea art has been indebted to Buddhism for what the traditional Korean art is. Thus under the influence of Buddism , Buddhist artwork formed 70% of Korea's registered culturdl assets. Recently, there has been an increased interest and pride In ancient Korean art and culture due to UNESCO's designation of Bulguksa and Sukgulam to international Cultural Assets. The purpose of the study was to present the art program models on Buddhist art based on discipline-based art education (DBAE) in order to understand Korean Buddhist artwork an improve children's aesthetic attitude toward Korean Buddhist art. The study included 1) theoretical background on Buddhist art in Korea and its impacts on Korean art and 2) disciplne-based approach in order to examine its applicability to present Korean art education setting. Ten art programs Buddhist based on DBAE presented in this study covered Korean Buddhist Art from Buddhist paintings (2-dimensional) to Buddhist sculptures and architectures (3-dimensional), from fine art to applied art (design), and also, from individual work to cooperative work.. Art educators and school teachers need to have their students understand our ancient buddhist art better to improve their aesthetic attitude in Korean traditional art. In addition, appropriate curriculum and program models for teaching Korean Buddhist art based on DBAE should be developed.

대구·경북지역의 김치 실태에 관한 조사

정용진,김주현,이주백 東國專門大學 1996 金龜論叢 Vol.3 No.1

대구·경북지역에 거주하는 주부 240명을 대상으로 김장을 준비하는 과정 형태, 방법, 종류, 보관방법, 입맛을 맞추는 기준 등에 관하여 연령별, 소득별, 결혼생활기간별, 특성을 비교한 결과, 김장을 준비하는 방법은 대부분의 연령층에서 혼자서 직접 한다는 응답이 가장 높게 나타났으며, 특히 70만원 이하의 저소득층에서 76.5%로 가장 높은 응답률을 보여 소득이 낮을수록 주부 혼자 직접 하는 경우가 많은 것으로 나타났다. 김장하는 방법을 배운 대상은 대부분의 주부들은 결혼전 친정어머니로부터 김치 담그는 법을 배우는 것으로 나타났다. 일반 가정에서 즐겨 먹는 김치로는 배추포기김치, 무김치, 동치미, 파김치, 고추김치순으로 분석되었다. 김장김치의 보관장소는 장독에 넣어 베란다에 둔다가 전체의 32.9%로 가장 높았고, 다음으로 플라스틱통에 담아 냉장고에 보관한다가 31.2%로 나타났다. 김치맛을 맞추는 대상에서는 연령별로 연령이 낮을수록 남편의 입맛에 맞추어 김장을 담는다는 응답이 높았고, 연령이 높을수록 본인의 입맛에 맞춘다는 응답이 상대적으로 높게 나타나는 특성을 보였으며, 중간 소득층에서는 남편의 입맛을 가장 고려하는 것으로 김장을 담글 때 가장 큰 걱정거리로 일손 부족, 김장에 대한 부담감, 김장 담그는 요령, 가족의 입맛, 보관 장소 경비문제의 응답순으로 나타났다.

전기자동차 운전을 위한 직류타여자 전동기의 쵸퍼제어

한경희,강승욱,김용주,정연택,이승환 明知大學校 産業技術硏究所 1994 産業技術硏究所論文集 Vol.13 No.-

Recently, the speed control of electric motorcar usually adapts the chopper control method by the development of power electronics and semiconductor manufacturing techniques. When the chooper control is adapted to the speed control of electric motorcar. D.C.series motor is mostly used because of the large starting torques and good control characteristics. But with respect to the economy, D.C. separately excited motor with shunt characteristics is profitable because of high adhesivesness and consumption. So, we compare the characteristics of the bilateral variable-ratio chopper controlled D.C. separately exited motor with that of the D.C. series motor theoretically and experimentally, and present the method which is able to simplify the main chopper circuit by selecting among the forward powering, forward regenerative braking, backward powering, and backward regenerative braking only by using the main chopper control signal. Also, control method is studied which has similar driving characteristics to that of the gasoline motorcar.

CD4+/CD8+ Ratio and Growth Differentiation Factor 8 Levels in Peripheral Blood of Large Canine Males Are Useful Parameters to Build an Age Prediction Model

Lee Han-Jun,Hong Seok-Jin,Kim Seung-Soo,Kwon Young-Yon,Choi Bong-Hwan,Choi Kyung-Mi,Choi Kyung-Mi,Lee Myung-Jin,Hwang Sun-Young,Park Kyoungwan,Joo Younghun,Song Hwayoung,Lee Cheol-Koo 대한남성과학회 2022 The World Journal of Men's Health Vol.40 No.2

Purpose:Purpose: To build an age prediction model, we measured CD4+ and CD8+ cells, and humoral components in canine periph-eral blood. Materials and Methods:Materials and Methods: Large Belgian Malinois (BGM) and German Shepherd Dog (GSD) breeds (n=27), aged from 1 to 12 years, were used for this study. Peripheral bloods were obtained by venepuncture, then plasma and peripheral blood mono-nuclear cells (PBMCs) were separated immediately. Six myokines, including interleukin (IL)-6, IL-8, IL-15, leukemia inhibitory factor (LIF), growth differentiation factor 8 (GDF8), and GDF11 were measured from plasma and CD4+/CD8+ T-lymphocytes ratio were measured from PBMC. These parameters were then tested with age prediction models to find the best fit model. Results:Results: we found that the T-lymphocyte ratio (CD4+/CD8+) was significantly correlated with age (r=0.46, p=0.016). Among the six myokines, only GDF8 showed a significant correlation with age (r=0.52, p=0.005). Interestingly, these two markers showed better correlations in male dogs than females, and BGM breed than GSD. Using these two age biomarkers, we could obtain the best fit in a quadratic linear mixed model (r=0.77, p=3×10-6). Conclusions:Conclusions: Age prediction is a challenging task because of complication with biological age. Our quadratic linear mixed model using CD4+/CD8+ ratio and GDF8 level showed a meaningful age prediction.

Cln 3-requiring 9 is a negative regulator of Th17 pathway-driven inflammation in anti-glomerular basement membrane glomerulonephritis

Lee, Hajeong,Lee, Jae Wook,Yoo, Kyung Don,Yoo, Joo-Yeon,Lee, Jung Pyo,Kim, Dong Ki,Chin, Ho Jun,Kim, Yon Su,Yang, Seung Hee American Physiological Society 2016 American Journal of Physiology Vol.311 No.3

<P>T helper 17 (Th17) lymphocytes promote renal inflammation in antiglomerular basement membrane glomerulonephritis (anti-GBM GN), and signal transducer and activator of transcription 3 (STAT3) mediates activation of Th17 lymphocytes by IL-6 and transforming growth factor-beta (TGF-beta). Cln 3-requiring 9 (Ctr9), a subunit of RNA polymerase-associated factor complex (PAFc), regulates the transcription of IL-6/STAT3-dependent genes. Here, we investigated the role of Ctr9 in regulating Th17-driven inflammation in anti-GBM GN. In mice, STAT3 beta or IL-17 knockout ameliorated anti-GBM autoantibody-induced renal injury. This phenomenon was associated with decreases in retinoic acid receptor-related orphan receptor gamma t (ROR gamma t), IL-17, phosphorylated STAT3, and proinflammatory cytokines. Compared with wild-type mice, Ctr9 increased in both STAT3 beta(-/-) and IL-17(-/-) mice injected with anti-GBM IgG, showing a negative correlation with Th17-related transcripts. Small interfering RNA (siRNA)-mediated knockdown of Ctr9 in intrarenal lymphocytes further upregulated Th17-related transcripts, consistent with repression of Th17 differentiation by Ctr9. Interestingly, Ctr9 was also expressed in human and mouse mesangial cells and downregulated in response to anti-GBM IgG or to TGF-beta plus IL-17. Ctr9 in mesangial cells was even more repressed in the presence of both anti-GBM IgG and Th17-activating cytokines. Consistent with these findings, renal biopsies obtained from patients with anti-GBM GN showed consistent downregulation of Ctr9 and upregulation of phosphorylated STAT3 and IL-17 in the glomerulus. We conclude that Ctr9 is a negative regulator of Th17 differentiation in anti-GBM GN and repressed by anti-GBM IgG and IL-17 in mesangial cells.</P>

Co-amplification of EBNA-1 and PyLT through dhfr-mediated gene amplification for improving foreign protein production in transient gene expression in CHO cells

Lee, Joo-Hyoung,Park, Jong-Ho,Park, Sun-Hye,Kim, Sun-Hong,Kim, Jee Yon,Min, Jeong-Ki,Lee, Gyun Min,Kim, Yeon-Gu Springer-Verlag 2018 Applied microbiology and biotechnology Vol.102 No.11

2009 개정 교육과정에 따른 초·중학교 미술과 교육과정 적용 방안

이주연(Lee Joo yon) 학습자중심교과교육학회 2012 학습자중심교과교육연구 Vol.12 No.4

본 연구는 ‘2009 개정 교육과정에 따른 초·중학교 교과 교육과정의 적용과 질 관 리 방안’이라는 총괄 연구 가운데 하나로, 2013년 초등학교 및 중학교에 연차적으로 적용되는 2009 개정 교육과정에 따른 미술과 교육과정의 성공적인 현장 정착을 위한 실천적 대안을 제시하고자 마련된 것이다. 2009 개정 교육과정부터 교육과정 해설서 가 제공되지 않기 때문에 오는 불편함을 해소하고 교과서가 현장에 적용되지 않은 상태에서 보다 구체적인 대안 마련을 목적으로 실시한 초등학교 교사 및 중학교 미 술교사 대상 설문조사를 토대로 다음과 같은 세 가지 교육과정 적용 방안에 중점을 두어 논의하였다. 첫째, 공통 교육과정의 축소에 따라 초등학교 5, 6학년 수준으로 내려온 기존의 중학교 ‘활용 중심의 학습 경험’을 위한 적용 방안, 둘째, 중학교 수준 으로 내려온 기존의 고등학교 ‘비판적 사고 중심의 학습 경험’을 위한 적용 방안, 마 지막으로 셋째, 2009 개정 교육과정에 따른 미술과 교육과정 ‘감상’ 영역에 새롭게 도입된 ‘미술비평’ 및 ‘미술사’을 위한 적용 방안 등이 그것이다. 앞으로 2009 개정 교 육과정에 따른 미술과 교육과정의 적용을 위한 교육과정의 재구성을 독려하기 위하 여 다양한 예시 제공이 뒤따라야 할 것이다. This study is part of the main research of ‘A study on the application and quality management of 2009 rev. Korean National Curriculum in primary and middle school’ by KICE(Korean Institute for Curriculum and Evaluation). The purpose of the study were 1) to help the new Korean National Curriculum be established firmly in school setting, and 2) to suggest practical alternatives. 2009 rev. Korean National Curriculum covers G1 through G9 instead of G10, thus critical thinking abilities which was developed in the stage of G10 should be reinforced at the last stage of the curriculum of G9. Although critical thinking abilities are important in each of curriculum contents of ‘Experience’, ‘Expression’, and ‘Art Appreciation’, class activities in ‘Art Appreciation’ were presented. ‘Sensory property-based’ → ‘basic concepts-based’ → ‘application-based’ → ‘value-based’ curriculum contents organization vs. ‘sensory property-focused’ → ‘basic concepts and skill-focused’ → ‘application skill and methods-focused’ → ‘critical thinking-focused’ learning experiences were compared. Especially application skill and methods-focused learning experiences in G5 & G6 stage were discussed. Finally application methods on the new sub concepts of ‘art history’ and ‘art criticism’ in ‘Art Appreciation’ area of 2009 rev. Korean National Art Curriculum were suggested. To strengthen learner-centered National curriculum, on-going quality management and control should be reinforced and maintained. For its successful settlement and activation, more detailed and various instructional materials and mentoring system should be followed.

농가 가족원의 생활시간 분석

이기영(Lee Ki-Young),조희금(Cho Hee-Keum),김외숙(Kim Oi-Sook),이연숙(Lee Yon-Suk),이승미(Lee Seung-Mi),홍두승(Hong Doo-Seung),조흥식(Cho Heung-Seek),김유경(Kim Yu-Kyung),김주희(Kim Joo-Hee) 가정과삶의질학회 2006 가정과삶의질연구 Vol.24 No.5

실험적 항기저막 사구체신염에 재조합 Uteroglobin 투여가 미치는 영향

김연수(Yon Su Kim),김현리(Hyun Lee Kim),이상구(Sang Goo Lee),양승희(Seung Hee Yang),김유영(You Young Kim),이세한(Sei Han Lee),정남현(Nam Hyun Chung),정현주(Hyun Joo Chung),김성균(Sung Kyun Kim) 대한신장학회 2002 Kidney Research and Clinical Practice Vol.21 No.4

목 적 : 면역복합체 침착으로 인한 사구체신염은 우리나라 말기신부전의 중요한 원인이다. 최근 면역조절기능을 가진 uteroglobin(UG)을 유전적으로 결핍시킨 동물모델에서 인체의 IgA 신염과 같은 사구체신염의 발생이 보고된 바 있다. 저자들은 생쥐에서 항기저막 사구체신염(aGBMGN)을 발생시키고 인체 재조합 UG를 이용하여 신염의 발생에 UG가 미치는 영향을 확인하고 신염 억제기전을 파악하고자 하였다. 방 법 : 토끼에서 생산한 Anti-GBM Ab 4.5 ㎎을 8주령의 생쥐(C57BL/6)에 정맥주사하여 aGBM-GN을 유발시킨 후, UG를 투여한 치료군, 질환대조군, 정상대조군에서 신염의 정도를 비교하였다. 또한 생쥐의 메산지움세포를 LPS로 자극한 후 UG에 의한 세포증식의 저해정도를 비교하였다. 결 과: 신염 유도 후 7일째 치료군은 정상대조군에 비해 요단백량/creatinine 값은 차이를 나타내지 않았지만, 질환대조군에 비해서는 유의한 감소를 나타내었다. 이러한 UG의 효과는 사구 체신염이 유도된 14일째까지 유지되었으며, 21일째에는 치료군과 질환대조군에서의 요단백/creatinine 값이 정상대조군에 비해 감소하였다. 조직학적으로 신염이 유도된 7일째, 질환대조군에서는 메산지움세포의 증식과 사구체의 50% 이상에서 세포성 반월상이 관찰되었으나, 치료군은 정상대조군과 유사한 조직학적 소견을 보였다. 생쥐 메산지움세포를 LPS로 자극한 후 UG를 투여 하였을 경우 LPS에 의한 세포 증식효과는 유의한 감소를 보였다. 결 론: 실험적으로 유도된 항기저막 사구체신염에 인체 재조합 UG를 투여함으로써 항기저막 사구체신염의 발생을 억제하였으며, 그 기전으로 메산지움세포 활성화 억제 가능성을 제시하였다. 이러한 결과는 신질환 진행 고위험군 집단의 유전자치료에도 이용될 수 있는 근거를 제시하였다고 할 수 있다. Glomerulonephritis(GN) is characterized by cognate immune responses against self or non-self antigen. It is suggested that the crescentic GN is a manifestation of cell-mediated immune response akin to delayed type hypersensitivity. Uteroglobin(UG) is a steroid-dependent, immunomodulatory, and cytokine-like protein. It was reported that UG prevented fibronectin(Fn) deposition in the glomeruli of normal mice to form Fn-UG heterodimers that competed with Fn self-aggregation. We hypothesized that UG would prevent the development of experimental GN induced by anti-glomerular basement membrane globulin(anti-GBM Ab) in mice through immunomodulatory properties. GN was induced by intravenous injection of 4.5㎎ rabbit anti-GBM Ab to mice(C57BL/6). Renal injury was evaluated at 7, 14, and 21 days thereafter. UG-treated mice(n=10) were received for 3 days(0.5 ㎎/mouse/day) beginning 1 hour after anti-GBM Ab injection. Also, disease-control mice(n=10) were received PBS for 3 days after anti-GBM Ab. Proteinuria was significantly reduced in the mice treated with UG when compared with the disease-control mice after 7 and 14 days of anti-GBM Ab injection. The amount of proteinuria was similar between UG treated and normal control mice. The mesangial matrix expansion and cellular crescent were markedly attenuated by the injection of UG. The proliferative responses of mesangial cells(C57BL/6) to LPS were blunted with the addition of UG in dose-dependent manner. In this study, we revealed the preventive effects of UG in the experimental model of glomerulonephritis. This result in turn could provide the basis for the treatment of human disease such as chronic glomerulonephritis.

50대 중년남성의 은퇴불안 적응과정 연구

이은주(Lee, Eun-Joo),이지연(Lee, Jee-Yon) 숭실대학교 영재교육연구소 2020 Global Creative Leader Vol.10 No.4

본 연구는 50대 중년남성들의 은퇴불안 적응과정을 일의 심리학 이론(Psychology of WorkingTheory: PWT) 관점에서 진로·심리상담 및 평생 교육학적 실체이론의 기초자료를 제시하는 것이다. 이러한 연구의 목적을 위해 Strauss & Corbin(1998)의 근거이론 연구방법을 사용하였다. 본 연구의 참여자들은 서울·수도권에서 현재 취업상태인 50대 중년남성 11명을 이론적 표본추출에 따라 모집하였다. 본 연구의 문제는 ‘개인·사회·문화적 맥락에서 현재 취업 상태인 50대 중년남성들의 은퇴불안 적응과정의 경험은 어떠한가?’이다. 근거이론으로 분석한 결과는 총 105개의 개념과 40개의 하위범주, 그리고 17개의 범주가 도출되었다. 또한, ‘자각기, 모색기, 수용기, 적응기’의 4단계로 변화하는 은퇴불안 적응과정 모형과 ‘단절로 인한 고통을 통해 노년기의 성숙성을 향해 나아감’이라는 핵심 범주가 발견되었다. 본 연구의 결과는 현재 취업상태인 50대 중년남성들의은퇴불안 적응과정에 대한 본질적인 인식과 적응과정에 대한 이해를 돕고, 1960∼1970년대에 성장기를 보낸 50대 중년남성들의 현실적인 경험을 파악했다는 점에 의의가 있다. 이러한 결과는 50대중년남성이라는 특수성을 고려하여 이들을 위한 정부·민간의 정책 지원체계를 마련해야 함을 시사한다. This study presents the basic data of career psychological counseling and lifelong pedagogicalreality theory from the perspective of the Psychology of Working Theory (PWT) of the retirementanxiety adjustment process of middle-aged men in their 50s. For the purpose of this study,Strauss and Corbin s (1998) grounded theory research method was used. Participants in this studyrecruited 11 middle-aged men in their 50s who are currently employed in Seoul and themetropolitan area according to theoretical sampling. The question of this study is What is theexperience of the retirement anxiety adjustment process of middle-aged men in their 50s who arecurrently employed in a personal, social and cultural context? As a result of analysis withgrounded theory, a total of 105 concepts, 40 subcategories, and 17 categories were derived. Inaddition, a model of the retirement anxiety adaptation process, which changes into four stages of‘a self-awareness period, a search period, a receptive period, and an adaptation period’, and acore category of ‘advancing toward maturity in old age through pain caused bydisconnection’was found. The results of this study were to help middle-aged men in their 50swho are currently employed in their retirement anxiety adjustment process and to understand theprocess of adaptation, and to grasp the realistic experiences of middle-aged men in their 50s whogrew up in the 1960s and 1970s, which has great significance. Theses results imply that agovernment-private policy support system should be prepared for them, taking into account thespecificity of being a middle-aged man in his 50s.