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Mechanical Properties of Recycled Concrete Reinforced by Basalt Fiber and Nano-silica
Yonggui Wang,Xuetong Zhang,Jinjin Fang,Xingguo Wang 대한토목학회 2022 KSCE JOURNAL OF CIVIL ENGINEERING Vol.26 No.8
In this study, basalt fiber (BF) and nanosilica (NS) were used to improve the mechanical properties of recycled concrete (RC), thereby promoting its utilization. The effect of BF and NS on the impact performance of RC was studied using the split Hopkinson pressure bar (SHPB) test. The internal microstructure of RC was analyzed by scanning electron microscopy, mercury intrusion porosimetry and nuclear magnetic resonance test. The results showed that, as the strain rate increased, the destruction mode transitioned from fracturing to crushing. Moreover, the impact compressive strength, dynamic increase factor, and total impact toughness increased. The replacement rate has little to no influence on the failure state, impact compressive strength and specific energy absorption. BF is conducive to enhancing the integrity and improving the impact compressive strength, peak strain and impact toughness. NS can reduce the pore content of mortar and the corrosion effect of the fiber surface, enhancing the compactness of the mortar and the bridging effect of the fiber. With an increase in NS content, the impact compressive strength, peak strain, and impact toughness increase, leading to greater destruction integrity. The results show that BF and NS can more effectively enhance the mechanical properties of RC.
Over-expression of PTEN on proliferation and apoptosis in canine mammary tumors cells
Jinjin Tong,Hua Zhang,Dongdong Sun,Yingxue Wang,Chao Yang,Yun Liu 한국통합생물학회 2016 Animal cells and systems Vol.20 No.6
Phosphatase and tensin homolog (PTEN) is an important tumor-suppressor gene which constitutes an important PI3K/Akt pathway by regulating the signaling of multiple biological processes, including apoptosis, metabolism, cell proliferation, and cell growth has been gaining increasing attention. However, the role of PTEN in regulating apoptosis of canine mammary tumors cells still needs further investigation. In this experiment, the effect of PTEN on proliferation and apoptosis in canine mammary tumors (CMT) cells was analyzed. As a result, gene and protein expression levels of apoptosis-related genes were detected. Eukaryotic expression vector pcDNA3.1+-PTEN were successfully constructed and stably transferred into canine CMT cells after geneticin (G418) selection. After pcDNA3.1+-PTEN transfection, compared with control group, the cells proliferation was inhibited and the cell apoptosis was increased in CMT cells. The expression of p-Akt was decreased and the apoptosis-related genes, such as caspase-3, caspase- 9, and Bax, were increased. These data serve to demonstrate the function of PTEN on apoptosis and gene regulatory in PI3K/Akt pathway in CMT cells. Collectively, our data link the tumorsuppressor activities of PTEN to the machinery controlling cell cycle through the modulation of signaling molecules whose signal target is the functional inactivation of the apoptosis gene product.
The Design of WLAN Wireless Access Protocol based on Certified NFC
Jinjin Pan,YunLi,ZhigangJIN,Xunjun Wang 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.1
Aiming at the problem of the security of the authentication mode of WLAN wireless access certification, this paper proposes a WLAN wireless access protocol based on NFC certification. The protocol adopts the Diffie-Hellman algorithm established in the unreliable air channel as anonymous AES encryption NFC security tunnel of decryption algorithm, and then using the public key password authentication mode to carries The non anonymous authentication out for the user applying for certification, while determines the conformance certification sides AES key. By shading Petric network modeling, experimental simulation proves that the protocol can effectively resist illegal access to attack and eavesdropping attacks.
Hybrid Model for Renewable Energy and Load Forecasting Based on Data Mining and EWT
Zhang Jinjin,Zhang Qian,Li Guoli,Wu Junjie,Wang Can,Li Zhi 대한전기학회 2022 Journal of Electrical Engineering & Technology Vol.17 No.3
Accurate renewable resource (RES) and load prediction play key roles in the power grid planning schemes, eff ective dispatch, and stable operation of power systems. The proportions of wind and solar energy continue to increase, leading to wind and light abandonment. Thus, the absorption of wind and photovoltaic power is particularly important. On the basis of accurately predicting load, wind power and photovoltaic output, the accommodation capacity of wind and photovoltaic power is analyzed. The work contains fi ve parts, as follows: (1) empirical wavelet transform (EWT) is used to decompose wind power and load. At the same time, isolated forest (iForest) and fuzzy C-means clustering (FCM) are used to process photovoltaic data. (2) Low frequency and intermediate frequency components of load are predicted by improved random forest (IRF). High frequency component of load is clustered by improved density-based spatial clustering of applications with noise (IDBSCAN). The processing model is selected on the basis of the characteristics of each class sample. Each component of wind power are predicted by IRF. (3) Photovoltaic power of each category is predicted by IRF. (4) Diff erent components of load and wind power data are added. The photovoltaic power forecast data are synthesized according to the time point. (5) The forecast value of load, wind power, and photovoltaic output of a city are comprehensively evaluated by the summarized prediction level indicators. Three accommodation indicators are used for analyzing the accommodation capacity of wind power and photovoltaic. Results show that the forecasting methods of load, wind power, and photovoltaic power can generate better forecasting results than conventional methods. The analysis results of supplementary prediction level and accommodation indices provide reference for eff ective grid dispatching, sustainable, and healthy energy development.
Wen Fule,Wang Lin,Fang Zhiyin,Zhu Jinjin,Zhang Yaqing 한국간호과학회 2020 Asian Nursing Research Vol.14 No.2
Purpose: The aim of the study was to modify and test the psychometric properties of the Chinese version of the work control scale (C-WCS). Methods: The translated scale was administered to 840 nurses in Shanghai. Validity was assessed in terms of content validity and construct validity using exploratory factor analysis and confirmatory factor analysis. Internal consistency and testeretest reliability were estimated using Cronbach a and the intraclass correlation coefficient. Results: Psychometric analyses of the C-WCS indicate high reliability and good content and construct validity. Conclusion: The C-WCS has good psychometric properties and can be used as a valid tool for measuring work control among nurses in China. The C-WCS will help to further explore the correlations between perceived work control and organizational quality indicators such as nurses' satisfaction, job stress, wellbeing, or intention to stay. It can also be used in nursing outcome studies of work control strategies.
Melatonin Attenuates Mitochondrial Damage in Aristolochic Acid-Induced Acute Kidney Injury
Sun Jian,Pan Jinjin,Liu Qinlong,Cheng Jizhong,Tang Qing,Ji Yuke,Cheng Ke,wang Rui,Liu Liang,Wang Dingyou,Wu Na,Zheng Xu,Li Junxia,Zhang Xueyan,Zhu Zhilong,Ding Yanchun,Zheng Feng,Li Jia,Zhang Ying,Yua 한국응용약물학회 2023 Biomolecules & Therapeutics(구 응용약물학회지) Vol.31 No.1
Aristolochic acid (AA), extracted from Aristolochiaceae plants, plays an essential role in traditional herbal medicines and is used for different diseases. However, AA has been found to be nephrotoxic and is known to cause aristolochic acid nephropathy (AAN). AA-induced acute kidney injury (AKI) is a syndrome in AAN with a high morbidity that manifests mitochondrial damage as a key part of its pathological progression. Melatonin primarily serves as a mitochondria-targeted antioxidant. However, its mitochondrial protective role in AA-induced AKI is barely reported. In this study, mice were administrated 2.5 mg/kg AA to induce AKI. Melatonin reduced the increase in Upro and Scr and attenuated the necrosis and atrophy of renal proximal tubules in mice exposed to AA. Melatonin suppressed ROS generation, MDA levels and iNOS expression and increased SOD activities in vivo and in vitro. Intriguingly, the in vivo study revealed that melatonin decreased mitochondrial fragmentation in renal proximal tubular cells and increased ATP levels in kidney tissues in response to AA. In vitro, melatonin restored the mitochondrial membrane potential (MMP) in NRK-52E and HK-2 cells and led to an elevation in ATP levels. Confocal immunofluorescence data showed that puncta containing Mito-tracker and GFP-LC3A/B were reduced, thereby impeding the mitophagy of tubular epithelial cells. Furthermore, melatonin decreased LC3A/B-II expression and increased p62 expression. The apoptosis of tubular epithelial cells induced by AA was decreased. Therefore, our findings revealed that melatonin could prevent AA-induced AKI by attenuating mitochondrial damage, which may provide a potential therapeutic method for renal AA toxicity.