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Enhancement of Impurity, Machinability and Mechanical Properties in Te-Treated 0Cr18Ni9 Steel
Jian‑bo Xie,Tian Fan,Han Sun,Zhi‑qi Zeng,Jian‑xun Fu 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.6
To enhance the machinability and mechanical properties of 0Cr18Ni9 steel, free-machining element Te was introduced inthis work. By adding various quantities of Te to steel, several machining and tensile tests were carried out. Results show thatwith Te addition of 530 ppm, the number of inclusion sizes below 1 μm disappeared. With raising Te from 360 to 530 ppm,more MnTe–MnS inclusions of 10–40 μm were in spherical shape; above 50 μm2, the ratio of inclusion area at 530 ppmwas greatest among all, and the large-sized inclusions occupied a larger share. Te addition contributed to the surfaces ofmachining steels more smooth. The ultimate tensile strength of steel increased from 399 to 435 MPa. Te resulted in growthof sulfides and improved the machinability of steel.
Sun, Jian-Da,Chen, Chuang-Zhen,Chen, Jian-Zhou,Li, Dong-Sheng,Chen, Zhi-Jian,Zhou, Ming-Zhen,Li, De-Rui Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5
Treatment responses of $N_0$ stage nasopharyngeal carcinoma were firstly analyzed comprehensively to evaluate long term outcomes of patients and identify prognostic factors. A total of 610 patients with $N_0$ NPC, undergoing definitive radiotherapy to their primary lesion and prophylactic radiation to upper neck, were reviewed retrospectively. Concomitant chemotherapy was administrated to 65 out of the 610. Survival rates of the patients were calculated using the Kaplan-Meier method and compared by log-rank test. Prognostic factors were identified by the Cox regression model. The study revealed the 5-year and 10-year overall, disease-free, disease-specific, local failure-free, regional failure-free, locoregional failure-free and distant metastasis-free survival rates to be 78.7% and 66.8%, 68.8% and 55.8%, 79.9% and 70.4%, 81.2% and 72.5%, 95.8% and 91.8%, 78.3% and 68.5%, 88.5% and 85.5%, respectively. There were 192 patients experiencing failure (31.5%) after radiotherapy or chemoradiotherapy. Of these, local recurrence, regional relapse and distant metastases as the first event of failure occurred in 100 (100/610, 16.4%), 15(15/610, 2.5%) and 52 (52/610, 8.5%), respectively. Multivariate analysis showed that T stage was the only independent prognostic factor for patients with $N_0$ NPC (P=0.000). Late T stage (P=0.000), male (P=0.039) and anemia (P=0.007) were independently unfavorable factors predicting disease-free survival. After treatment, satisfactory outcome wasgenerally achieved in patients with $N_0$ NPC. Local recurrence represented the predominant mode of treatment failure, while T stage was the only independent prognostic factor for overall survival. Late T stage, male gender, and anemia independently predicted lower possibility of the disease-free survival.
POSITIVE SOLUTION FOR FOURTH-ORDER FOUR-POINT STURM-LIOUVILLE BOUNDARY VALUE PROBLEM
Jian-Ping Sun,Xiao-Yun Wang 한국전산응용수학회 2010 Journal of applied mathematics & informatics Vol.28 No.3
This paper is concerned with the following fourth-order four-point Sturm-Liouville boundary value problem [수식]Some sufficient conditions are obtained for the existence of at least one positive solution to the above boundary value problem by using the well-known Guo-Krasnoselskii fixed point theorem.
DESIGN AND IMPLEMENTATION OF LONG-DISTANCE SERIAL COMMUNICATION BASED ON WEB
SUN Jian-mei,ZHOU Da-yong 한국멀티미디어학회 2006 한국멀티미디어학회 국제학술대회 Vol.2006 No.-
With the development of the information industry such as internet and so on, Long-distance controlling on the intelligent equipment becomes the direction of the modem people's lives, Long-distance serial communication is good for researching. The paper discusses the long-distance serial communication Based on Web, it introduces the basic structure and the process of realization of the system, analyzes and realizes the software flow of the serial communication, presents the instance of the Long-distance controlling on the manipulator, the same time, it prospects the development of the long-distance based on the embedded system.
Jian Sun,Chen Guo,Lei Liu,Qihe Shan 제어·로봇·시스템학회 2023 International Journal of Control, Automation, and Vol.21 No.4
This paper deals with the coordinated output regulation problem of heterogeneous multi-agent systems under switching disconnected topologies. The main difficulty is that the outputs of some disconnected agents can inevitably deviate from the divergent trajectories of exosystems across some periods. To break through this challenge, we propose an interesting approach named piecewise time unit approach, in which each switching interval consists of several time units. By analyzing the trajectories of error states under the distributed observer-based control, the decreasing properties of switching behaviors can be obtained to overcome the divergence of error states. Based on this, the sufficient conditions guaranteeing the output regulation can be obtained. Finally, a simulation example is given to demonstrate our results.
Jian Shi,Huichai Yang,Xiaoyang Duan,Lihua Li,Lulu Sun,Qian Li,Junjun Zhang 연세대학교의과대학 2016 Yonsei medical journal Vol.57 No.3
Purpose: The present study aimed to investigate the value of apolipoproteins, including ApoA-1, ApoC-III, and ApoE, in patients with small cell lung cancer (SCLC) as potential biomarkers for diagnosis, prognosis, and cancer progression. Materials and Methods: Lung samples were collected from 89 patients with SCLC. Nineteen lung samples from non-small cell lung cancer (NSCLC) patients and 12 normal lung tissues were used as controls. Expression profiles of ApoA-1, ApoC-III, and ApoE in different samples were examined using immunohistochemical methods, and the expression levels were correlated with cancer types, treatment, and outcomes using chi-square and Mann-Whitney tests. Results: Expression of ApoA-1 and ApoC-III in SCLC was significantly different, compared with that in NSCLC and normal lung tissues, and was correlated with recurrence of SCLC. Patients undergoing neoadjuvant chemotherapy before surgery showed significantlyreduced expression of ApoA-1 and increased expression of ApoC-III and ApoE. Nevertheless, the expression levels of ApoA-1, ApoC-III, and ApoE were not correlated with SCLC staging. Conclusion: ApoA-1 and ApoC-III may be used as differentiating and predictive markers for SCLC. ApoA-1, ApoC-III, and ApoE may be used to monitor the efficacy of chemotherapy.
Melatonin Attenuates Mitochondrial Damage in Aristolochic Acid-Induced Acute Kidney Injury
Sun Jian,Pan Jinjin,Liu Qinlong,Cheng Jizhong,Tang Qing,Ji Yuke,Cheng Ke,wang Rui,Liu Liang,Wang Dingyou,Wu Na,Zheng Xu,Li Junxia,Zhang Xueyan,Zhu Zhilong,Ding Yanchun,Zheng Feng,Li Jia,Zhang Ying,Yua 한국응용약물학회 2023 Biomolecules & Therapeutics(구 응용약물학회지) Vol.31 No.1
Aristolochic acid (AA), extracted from Aristolochiaceae plants, plays an essential role in traditional herbal medicines and is used for different diseases. However, AA has been found to be nephrotoxic and is known to cause aristolochic acid nephropathy (AAN). AA-induced acute kidney injury (AKI) is a syndrome in AAN with a high morbidity that manifests mitochondrial damage as a key part of its pathological progression. Melatonin primarily serves as a mitochondria-targeted antioxidant. However, its mitochondrial protective role in AA-induced AKI is barely reported. In this study, mice were administrated 2.5 mg/kg AA to induce AKI. Melatonin reduced the increase in Upro and Scr and attenuated the necrosis and atrophy of renal proximal tubules in mice exposed to AA. Melatonin suppressed ROS generation, MDA levels and iNOS expression and increased SOD activities in vivo and in vitro. Intriguingly, the in vivo study revealed that melatonin decreased mitochondrial fragmentation in renal proximal tubular cells and increased ATP levels in kidney tissues in response to AA. In vitro, melatonin restored the mitochondrial membrane potential (MMP) in NRK-52E and HK-2 cells and led to an elevation in ATP levels. Confocal immunofluorescence data showed that puncta containing Mito-tracker and GFP-LC3A/B were reduced, thereby impeding the mitophagy of tubular epithelial cells. Furthermore, melatonin decreased LC3A/B-II expression and increased p62 expression. The apoptosis of tubular epithelial cells induced by AA was decreased. Therefore, our findings revealed that melatonin could prevent AA-induced AKI by attenuating mitochondrial damage, which may provide a potential therapeutic method for renal AA toxicity.
Influence of Various Heat Treatment Stages on Evolution of Microstructure and Grain in H407 Steel
Jian Sun,Kai Ji,Chen Wei Jiang,Yun Chang Zhang 대한금속·재료학회 2016 METALS AND MATERIALS International Vol.22 No.5
Regarding heat treatment as one of the main methods for improving property of die steel, dead annealing, quenching, once tempering, twice tempering, and thrice tempering treatment of H407 die steel were conducted in this thesis. Microstructure conversion and grain size development in various stages of heat treatment were analyzed, and then magnitude, shape, and distribution of secondary phase during heat treatment were investigated to explore the function mechanism of microalloyed elements on evolution of microstructure and grain during heat treatment. The steel achieves homogeneous microstructure and composition after this heat treatment. The final phase constituent is α and γ phase as well as the final microstructure consists of tempered martensite, trace retained austenite and granular carbides. A large number of fine and dispersive MC as well as M7C3 type granular carbides containing V, Mo and Cr precipitate in trice tempered microstructure. After this heat treatment grain is finer with grain size of 5.96 μm.
How to Become an Elite Wushu (Kung-fu) Routine Athlete? Research on Development Factors
Jian Sun,Shali Hu,Xin Liu,May-Helen P. Stroemsmo 아시아건강운동학회 2019 Journal of Asian Society for Health & Exercise Vol.1 No.2
In order to know the developing pattern of the Wushu routine elite athletes, the research methods such as questionnaire, interview, case study and statistical analysis were used in this study. Through the study of the development of Chinese Wushu routine athletes, we found that there are five factors that influenced the developments of those athletes: the innate motivation, the external motivation, material guarantee, interpersonal environment and the choosing of opportunity. These five major key elements do not exist in isolation, but each take different proportion in different periods, and closely related and interact with each other. They have formed a dynamic open system.