혈액 및 비장조직에서 일산화탄소 헤모글로빈 농도에 관한 연구 : A Comparison of CO-Hb in Blood and Spleen Specimens

이진훈,오세진,김유나,이진숙,유재훈,장성길 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-

韓國人의 各 臟器組織中 靑酸鹽의 微量分布에 關한 硏究(Ⅱ)

張成吉,金恩浩,金英雲,李鎭勳,柳在薰,權五星,金明德,吳世珍,金由那 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-

Flavobacterium meningosepticum에 의한 균혈증 1예

장성원,유진홍,진승원,김선우,김연식,박순민,이대훈,최민호,최주연,신완식,강문원,강지민 대한화학요법학회 1997 대한화학요법학회지 Vol.15 No.1

1996년 6월 카톨릭대학교 부천성가병원에 뇌경색으로 입원했던 61세 남자 환자의 혈액에서 Flavobacterium meningosepticum을 분리하였다. 환자는 폐렴을 동반한 패혈증의 예로 ceftriaxone과 metronidazole을 투여하였으나 입원 48시간만에 사망하였다. Flabovacterium meningosepticum is a rae cause of nosocomial infection which shows multi-drug resistance. It mainly invades patients with impaired immunity. Recently, we experienced a case of F. meningosepticum bacteremia in a patient with chronic debilitated state owing to stroke. The clinical progress was so rapid that he died within 48 hours. Blood culture revealed F. meningosepticum which showed characteristic yellow colony in blood agar plate.

GMDP 신경망 알고리즘과 PID 제어기를 이용한 효율적인 PLANT 제어에 관한 연구

장진청,설재훈,장종승,추연규,임영도 동아대학교 공과대학 부설 한국자원개발연구소 1995 硏究報告 Vol.19 No.2

Adapative control theory or parameter tuning of PID controller is mainly limited in linear systems. But in this paper, using a nonlinear mapping capability of NNS, we derive a realtime tuning method of PID controller based on a Back-Propagation method of single GMDP NN. A variety of neural models, especially higher-order networks, are known to computationlly powerful for complex application. While they have advantages over traditional multilayered perceptrons, the uniformity in their network structures, learning algorithms and loop time creates practical problems. Thus this paper evaluates the capability between MLP and GMDP for performing velocity control. Backpropagation is applied to the GMDP as learning rule.

안구적출에 따른 위둔덕의 Calbindin D-28k과 c-fos의 변화에 관한 연구

김명,김기훈,김주영,하현철,안명수,김장민,조향훈,정명섭,장인엽 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.2

Changes of Calbindin D-28k- and c-fos-immunoreactivities in the superior collicuclus after Eye Enucleation. Objective and methods: Calcium-binding proteins (CBPs) play an important role in the protection, differentiation and reorganization of the central nervous system. The effects of neonatal retinal deafferentation on a CBPs, calbindin D-28k were examined immunohistochemically in the superficial layer of the rat superior colliculus. Also early gene familly c-fos was examined to evaluate the neuronal characteristics in the superior colliculus after monocular enucleation. Results: On the experimental side of superior colliculus, the number of calbindin D-28k-immunoreactive (IR) cells was reduced (77.4% compared to control), but not fibers. Appearance of c-fos-like immunoreactivity was represented much more in the ipsilateral superior colliculus than contralateral side within 24h after eye enucleation. Conclusion: These results suggest that the changes of retinotectal projection may alter the expressional pattern of calbindin D-28k and c-fos expression.

스프레드시트와 Green 정리를 이용한 철근 콘크리트 단주의 해석 및 설계

진치섭,한상중,엄장섭,이승훈 釜山大學校生産技術硏究所 1998 生産技術硏究所論文集 Vol.55 No.-

구조물 설게에서, 압축과 2축 휨을 동시에 받는 기둥 설계를 자주 접하게 된다. 이러한 부재의 해석과 설계는, 모멘트 평형에 따른 여러 변수들의 값을 동시에 구하기 위하여 반복적인 작업이 필요하기 때문에 많은 시간을 요구한다. 본 연구에서는 압축과 2축 휨을 받는 철근 콘크리트 단주를 해석 및 설계할 수 있는 컴퓨터 프로그램 COL2를 개발하였다. 프로그램 COL2는 스프레드시트 프로그램 중의 하나인 엑셀을 이용한 사용자 위주 환경의 프로그램으로 개발되었다. Green정리를 사용하여 임의 형상의 역학적 특성을 계산하였다. In structural design, columns subjected to combined compression and biaxial bending are frequently encountered. The analysis and design of such members, are both time consuming and demanding because an iterative procedure is reuqired in order to simultaneously evaluate a number of variables to achieve moment equilibrium. A computer program COL2 is developed to analyze and design reinforced concrete short columns subjected to combined compression and bizxial bending in this study. The program COL2 has been developed for user-friendly environment using MS-Excel one of the spreadsheets program. The mechanical properties of generic shapes was calculated by Green's theorem.

韓國人의 血液 및 各 臟器組織中 靑酸鹽의 微量分布에 關한 硏究 : Concerning Micro Distribution of Cyanide in Human Organs

張成吉,金恩浩,金英雲,李鎭勳,趙承衍 內務部 國立科學搜査硏究所 2002 國立 科學 搜査 硏究所 年報 Vol.34 No.-

植物凝集素 Dolichos lablab L.로 分類된 사람 血淸型에 관한 硏究

張訓梓,文國鎭 고려대학교 의과대학 1988 고려대 의대 잡지 Vol.25 No.1

Since the introduction of phytohemagglutinin (PHA) by Stillmark in 1898, PHA contributed to modicolegal field with new classification of blood types by their agglutination activities to human red blood cells and some of them have been used as lectins instead of antisera. Recently there were reported human serum types classified by their inhibition properties to agglutination reaction of panphytagglutinins with various red blood cells. To classify the serological relationships of human serum types classified by their agglutination activities to cat and rabbit red blood cells, and by their agglutination inhibition properties to D. lablab extract with cat and rabbit red blood cells, agglutination test and agglutination inhibition test with 1409 human sera were carried out. The results could be summarized as follows: 1. Human sera were classfied by their agglutination activities to cat red blood cells, and all rabbit red blood cells were agglutinated by human sera. 2. Human sera were also classified by their agglutination inhibition properties to D. lablab extract with cat and rabbit red blood cells and no serological relationship were demonstrated between them. 3. There were serological relationships between the human serum types classified by their agglutination activities and by their agglutination inhibition properties mentioned. 4. Human sera could be classified into 8 types by combination of their agglutination activities and by their agglutination inhibition properties to D. lablab extract with cat and rabbit red blood cells.

2003년 국내 중증급성호흡기증후군 진료 현황 및 문제점 분석

이진수,김은실,정문현,백제중,정선화,안주희,최영화,이선희,고철우,김성범,김민자,박승철,기현균,송재훈,최상호,김양수,이상오,조용균,박영훈,정숙인,김연숙,이흥범,손창희,장성희,정희진,김우주 대한감염학회 2004 감염과 화학요법 Vol.36 No.3

목적 : 2002년 말 중국에서 SARS가 발생한 이후 국내에서도 2003년 10월까지 총 3명의 추정환자, 17명의 의심환자가 보고되었다. 향후 추가적인 SARS의 유행이 우려되는 상황에서, 그간의 SARS 환자 진료에 있어서의 실질적인 준비사항, 진료 현황 등에 대한 조사를 통해 문제점을 파악하여, 향후 더 나은 대비가 될 수 있도록 개선점을 제시하고자 하였다. 재료 및 방법 : SARS로 의심되는 환자를 진료 경험이 있는 병원의료진을 대상으로 2003년 10월에 설문조사를 실시하였다. 설문에는 SARS 환자 진료 시의 실질적인 조치, 진료 현황, 병실, 응급실 및 외래에서의 격리 시설과 준비사항, 보건당국의 관리와 지원에 관한 사항을 포함하였다. 결과 : 대상이 되는 22개 병원 중 17개(17/22, 77.2%) 병원이 설문에 응하였다. SARS 환자를 위한 격리실은 응급실, 외래, 일반병실 및 중환자실에서 각각 9개(9/17, 52.9%), 5개(5/17, 29.4%), 15개(15/16, 93.7%), 4개(4/16, 25%) 병원에서 음압처리가 되어있지 않은 일인실 혹은 다인실이 사용되었고, 1개(1/16, 6.3%) 병원에서만 일반병실에서 음압격리실이 운영되었다. 입원환자의 진찰 시 개인보호구의 착용은 거의 모든 의료기관에서 이루어졌다. 보건당국에서 SARS지정병원의 시설 등을 사전에 확인한 곳은 1곳(1/12, 8.3%)이였고, 14개 병원(14/15, 93.3%)에서는 보건당국에 의뢰한 검사결과를 통하 받지 못하였다. 결론 : 의료기관에서 SARS 환자용 격리실뿐만 아니라 기존의 격리실 설비 등이 미흡하였으며, 특히 중환자실 및 외래의 준비가 더욱 부족하였다. 보건당국의 의료기관에 대한 종합적인 지원이 부족하였고, 병원과의 원활한 연계가 잘 이루어지지 않았다. SARS 만이 아닌 격리를 필요로 하는 질환의 적절한 진료를 위해 향후 병원 시설의 정비와 정부차원에서의 보다 구체적이고 실질적인 대책마련이 필요하다. Background : There was an worldwide outbreak of the Severe Acute Respiratory Syndrome (SARS) originated from China in late 2002. During that period three cases of suspected SARS and 17 cases of probable SARS were reported in Korea. With the concerns about the reemergence of SARS-coV transmission, it is important to be prepared for any possibility. So, this study is aimed to analysis the past measures in managing SARS and propose the amendatory plans to improve the preparedness. Materials & Methods : Questionnaires were collected among clinicians with any experience in managing the probable or suspected SARS cases in Oct. 2003. 17 out of 22 hospitals responded to the questionnaire. The contents in the questionnaire were practical activities, personal equipments, response plans, isolation facilities in emergency centers, outpatient clinics, general wards and intensive care units, and relationship with the public health department. Results : The dedicated isolation rooms in emergency centers, outpatient clinics, general wards, and intensive care units were prepared in 9 (9/17, 52.9%), 5 (5/17, 29.4%), 15 (15/16, 93.7%), and 4 (4/16, 25.0%) hospitals, respectively. Except for one hospital that newly made negative pressure room for SARS, single or multi-bed rooms without airborne infection control were used in all the other hospitals. The personal precaution principles were kept quite well in general wards. Before the designation of SARS hospital by the public health department prior evalution to see if the hospital was suitable for managing SARS was conducted in only 1 (1/12, 8.3%) hospital. The results of laboratory diagnosis were reported back in 1 (1/15, 6.6%) hospital. Conclusions : The isolation facilities which can control airborne infection were almost deficient not only for SARS but also for other respiratory transmissible diseases. For the infection control of transmissible diseases including SARS, more investment is needed on medical facilities and comprehensive support from the public health department required.

접촉성 피부염 환자와 정상인의 첩포검사에 관한 연구

박장규,성열훈,성범진 충남대학교 의과대학 지역사회의학연구소 1989 충남의대잡지 Vol.16 No.2

Numerous studies on epidemiological aspects of contact dermatitis due to various causative antigens have been reported n recent year in Korea. However, degree of sensitization in healthy persons was not reported till now in Korea. We have performed the patch test on patients with contact dermatitis and healthy persons. The study results were as follows; 1. Percent of positive reaction in patients with contact dermatitis was 45.9%. The common allergens of positive reactions were nickel sulfate(21.6%), potassium dichromate (10.8%), neomycin sulfate (8.1%), Balsam of Peru (8.1%), mercuric chloride, ammoniated (5.4%), p-phenylenediamine(5.4%), cinnamic alcohol(5.4%), ethylenediamine dihydrochloride (2.7%), formaldehyde(2.7%), wool wax alcohol(2.7%), thimerosal (2.7%), mercaptobenzothiazole(2.7%), imidazolidinyl urea(2.7%) in order of frequency. 2. Percent of positive reaction in healthy persons was 10.3% and the common allergens were mercuric chloride, ammoniated(5.2%), nickel sulfate(3.1%), cinnamic alcohol(2.1%), ethylenediamine dihydrochloride(1.0%), formaldehyde(1.0%), epoxy resin(1.0%), in order of frequency. We conclude that allergens associated with metals and drugs seem to be the dominant causes of contact dermatitis and healthy persons.