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      • SCOPUS

        Hybrid Patterns Recognition of Control Chart Based on WA-PCA-PSO-SVM

        Liu Yan-zhong,Zhang Hong-lie,Liu Yan-ju,Jiang Jin-gang 보안공학연구지원센터 2014 International Journal of Control and Automation Vol.7 No.10

        Based on the analysis of the defect of traditional model, this paper proposes a new control chart pattern recognition model, which includes Wavelet Analysis (WA), Principal Component Analysis (PCA), Particle Swarm Optimization (PSO) and Support Vector Machine (SVM). WA is good to eliminate noise control chart anomaly pattern recognition of the adverse effect. PCA eliminates the redundant information of data between SVM and reduces the input dimension and computational complexity. PSO algorithm optimizes the parameters of SVM and the establishment of the optimal control chart anomaly pattern classifier can solve the problem optimal parameters of SVM. The simulation results show that the model is feasible, the results are reliable. This algorithm improves the control chart abnormal state average recognition accuracy and be used in the machining process real-time monitoring.

      • SCISCIESCOPUS

        Metabolic engineering of Corynebacterium glutamicum for increasing the production of L-ornithine by increasing NADPH availability.

        Jiang, Ling-Yan,Zhang, Yuan-Yuan,Li, Zhen,Liu, Jian-Zhong Published by Stockton Press on behalf of the Socie 2013 Journal of industrial microbiology & biotechnology Vol.40 No.10

        <P>The experiments presented here were based on the conclusions of our previous proteomic analysis. Increasing the availability of glutamate by overexpression of the genes encoding enzymes in the L-ornithine biosynthesis pathway upstream of glutamate and disruption of speE, which encodes spermidine synthase, improved L-ornithine production by Corynebacterium glutamicum. Production of L-ornithine requires 2 moles of NADPH per mole of L-ornithine. Thus, the effect of NADPH availability on L-ornithine production was also investigated. Expression of Clostridium acetobutylicum gapC, which encodes NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, and Bacillus subtilis rocG, which encodes NAD-dependent glutamate dehydrogenase, led to an increase of L-ornithine concentration caused by greater availability of NADPH. Quantitative real-time PCR analysis demonstrates that the increased levels of NADPH resulted from the expression of the gapC or rocG gene rather than that of genes (gnd, icd, and ppnK) involved in NADPH biosynthesis. The resulting strain, C. glutamicum δAPRE::rocG, produced 14.84 g l?1 of L-ornithine. This strategy of overexpression of gapC and rocG will be useful for improving production of target compounds using NADPH as reducing equivalent within their synthetic pathways.</P>

      • KCI등재

        A note on the value distribution of $f^2(f')^n$ for $n\geq 2$

        Yan Jiang 대한수학회 2016 대한수학회보 Vol.53 No.2

        Let $f$ be a transcendental meromorphic function in the complex plane $\mathbb{C}$, and $a$ be a nonzero constant. We give a quantitative estimate of the characteristic function $T(r,f)$ in terms of $N(r,1/(f^2(f')^n-a))$, which states as following inequality, for positive integers $n\geq 2$, $$T(r,f)\leq \left(3+\frac{6}{n-1}\right)N\left(r,\frac{1}{af^2(f')^n-1}\right)+S(r,f).$$

      • 《佩觽》的构成和编排体例研究

        Jiang Yan 단국대학교 한문교육연구소 2021 International Han-character Education Research Vol.4 No.1

        《佩觽》는 오대 송초 郭忠恕가 저술한 자서로, 위진시대 이후 자형을 판별한 자서들의 종합 판이다. 이 책의 구성과 배열은 매우 독특한 형식적 특성을 지니고 있다. 구성은 “三科”와 “十 段”으로 나뉜다. “三科”는 이론 영역으로 “造字之旨”, “四声之作”, “传写之差”으로 설명되고 있다. “十段”은 구체적인 내용으로 표제자를 음가에 따라 열 가지로 배열하는 형식으로 구성되 어 있다. 결론적으로 이 책의 구성과 배열의 특성은 다른 자서에서 보기 어려운 특성을 지니고 있기 때문에 이 구성과 배열의 특성과 작용을 분석하는 것은 의미있는 연구 영역이다. 특히 지금의 문자학이 자전학 연구에서 중요한 가치와 의의를 지닌다. Pei Xi is a book of Chinese characters written by Guo Zhongshu in WuDai. It epitomized the dictionaries of Chinese characters which are produced since WeiJin. The stylistic rules and layout of Pei Xi are unusual. This thesis will analyse them and draw a conclusion by summing up the values of Pei Xi, as well as its influences. In short, it is worth standardizing Chinese characters and word dictionary and researching their developing rules.

      • Life Science : Chemical Constituents of Cynanchum wilfordii and the Chemotaxo-nomy of Two Species of the Family Asclepiadacease, C wilfordii and C auriculatum

        ( Yan Fu Jiang ),( Hyun Gyu Choi ),( Ying Li ),( Yu Mi Park ),( Jong Hwa Lee ),( Do Hoon Kim ),( Je Hyun Lee ),( Jong Keun Son ),( Min Kyun Na ),( Seung Ho Lee ) 영남대학교 약품개발연구소 2012 영남대학교 약품개발연구소 연구업적집 Vol.22 No.0

        Definitive identification of original plant species is important for standardizing herbal medicine. Although only the dried roots of Cynanchum wilfordii (Asclepiadaceae) are prescribed as Cynanchi WilfordiiRadix in Korean Pharmacopoeia, the roots of C. wilfordii and C. auriculatum are often misused in the Korean herbal market due to their morphological similarity and similar name. Therefore, it would be very useful to discover an effective chemical marker for the identification of the two species. To this end, we carried out a phytochemical study on the roots of C. wilfordii. As a result, twenty compounds were isolated from the roots of C. wilfordii and their chemical structures were identified as β-sitosterol (1), wilfoside C1N (2), wilfoside C3N (3), wilfoside K1N (4), methyleugenol (5), wilfoside C1G (6), cynauriculoside A (7), daucosterol (8), 2,4-dihydroxyacetophenone (9), cynandione A (10), 2,5-dihydroxyacetophenone (11), acetovanillone (12), p-hydroxyacetophenone (13), sucrose (14), conduritol F (15), geniposide (16), succinic acid (17), 3-(β-D-ribofuranosyl)-2,3-dihydro-6H-1,3-oxazine-2,6-dione (18), bungeiside A (19), cynanoneside B (20). Among them, compounds 15, 16, 18, 19, and 20 were isolated for the first time from this species. Furthermore, conduritol F (15) was demonstrated to be contained only in C. wilfordii. Therefore, it may be useful as a chemical marker to identify the two species C. wilfordii and C. auriculatum.

      • KCI등재

        Evaluation of the Efficacy of a Lactobacilli-Based Teat Detergents for the Microbiota of Cows Teats Using an Untargeted Metabolomics Approach

        Yan Rui,Ji Zhongqing,Fan Jiaqi,Li Jiang,Ren Yan 한국미생물·생명공학회 2024 Journal of microbiology and biotechnology Vol.34 No.1

        Teat cleaning pre- and post-milking is important for the overall health and hygiene of dairy cows. The purpose of this research was to evaluate the effectiveness of a teat detergents based on lactic acid bacteria according to changes in somatic cell count and cow-milk metabolites. Sixty-nine raw milk samples were collected from 11 Holstein-Friesian cows in China during 12 days of teat cleaning. An ultra-performance liquid chromatography-quadrupole-time of flight mass spectrometry-based untargeted metabolomic approach was applied to detect metabolomic differences after treatment with lactic acid bacteria and chemical teat detergents in cows with subclinical mastitis. The results suggest that the lactobacilli-based teat detergents could reduce somatic cell count and improve microhabitat of cow teat apex by adjusting the composition of metabolites. Furthermore, the somatic cell count could be decreased significantly within 10 days following the cleaning protocol. Lactic acid bacteria have the potential to be applied as a substitution to teat chemical detergents before and after milking for maintenance of healthy teats and breasts. Further, larger scale validation work is required to support the findings of the current study.

      • KCI등재

        A Study on the Influence of Personality Traits of College Students on the Way of Coping with Employment Stress and Entrepreneurial Intention in the Post-Epidemic Era

        Jiang-Bo Yan,Ya-Li Fang,Chi Gong 사회혁신기업연구원 2023 혁신기업연구 Vol.8 No.2

        With the arrival of the "post-epidemic era", the impact of multiple factors such as the epidemic and domestic and foreign economic weakness on the employment and entrepreneurship of graduates is still continuing and deepening, and youth employment has become a worldwide problem. Self-employment has gradually become a new employment channel, and self-employment of college students not only provides a large number of new jobs for the society, but also helps to alleviate the social employment pressure and the severe employment situation of college students. At present, exploring the factors influencing college students' entrepreneurial intention has become a hot topic in the field of entrepreneurship research. In this study, it is important to study the mechanism of each factor by constructing a model of the influencing factors of college students' entrepreneurial intention. The main conclusions from the study are as follows. First, all four personality traits have a significant positive influence on entrepreneurial intention, and college students with the above personality traits are more likely to have entrepreneurial intention, and the way of coping with employment pressure plays a mediating role in the relationship between personality traits and entrepreneurial intention. Based on this, the study provides valuable theoretical implications for research in this area and practical implications for how schools can improve students' entrepreneurial awareness.

      • KCI등재

        The Pilot Study for Waste Oil Removal from Oilfields by Acinetobacter johnsonii Using a Specialized Batch Bioreactor

        Yan Jiang,Xianming Zhang,Guoxu Chen,Yu Shen,Liang Zhou 한국생물공학회 2012 Biotechnology and Bioprocess Engineering Vol.17 No.6

        The batch bioreactor with a maximum capacity of 0.28 m3 was designed and manufactured according to oilfield conditions Acinetobacter johnsonii ioslated from waste oil in an aerobic environment was employed to cleanse waste oil and wash-down water using the bioreactor in a pilot scale. The aerating process was optimized from 2 to 4 m3/h corresponding to the different cell growth phases, ensuring sufficient dissolved oxygen and avoiding cell damage from the shearing forces due to strong aeration. The bio-treatment of waste oil underwent two stages:one was the wettability reversal of inorganic admixtures from oil phase into waster phase through enlarged wetting angles, and the other was the bio-flocculation in waster phase by intermediate metabolites excreted by cells. Finally,inorganic admixtures were effectively removed from waste oil and wash-down water at the optimal conditions, with the content less than 0.5% in oil phase and turbidity and sulfide less than 100 NTU and 1 mg/L in the water phase,respectively. Such bio-treatment made the oil-water interface clear against oil and water emulsification and in favor of smooth reclamations for waste oil and wash-down water.

      • KCI등재

        Fusion Expression and Immunogenicity of EHEC EspA-Stx2A1 Protein: Implications for the Vaccine Development

        Yan Cheng,Youjun Feng,Ping Luo,Jiang Gu,Shu Yu,Wei-jun Zhang,Yan-qing Liu,Qing-xu Wang,Quan-ming Zou,Xu-hu Mao 한국미생물학회 2009 The journal of microbiology Vol.47 No.4

        Shiga toxin 2 (Stx2) is a major virulence factor for enterohemorrhagic Escherichia coli (EHEC), which is encoded by λ lysogenic phage integrated into EHEC chromosome. Stx2A1, A1 subunit of Stx2 toxin has gathered extensive concerns due to its potential of being developed into a vaccine candidate. However, the substantial progress is hampered in part for the lack of a suitable in vitro expression system. Here we report use of the prokaryotic system pET-28a::espA-Stx2A1/BL21 to carry out the fusion expression of Stx2A1 which is linked to E. coli secreted protein A (EspA) at its N-terminus. Under the IPTG induction, EspA- Stx2A1 fusion protein in the form of inclusion body was obtained successfully, whose expression level can reach about 40% of total bacterial protein at 25°C, much higher than that at 37°C. Western blot test suggested the refolded fusion protein is of excellent immuno-reactivity with both monoclonal antibodies, which are specific to EspA and Stx2A1, respectively. Anti-sera from Balb/c mice immunized with the EspA-Stx2A1 fusion protein were found to exhibit strong neutralization activity and protection capability in vitro and in vivo. These data have provided a novel feasible method to produce Stx2A1 in large scale in vitro, which is implicated for the development of multivalent subunit vaccines candidate against EHEC O157:H7 infections.

      • KCI등재

        Additive Role of the Vestibular End Organ and Baroreceptors on the Regulation of Blood Pressure in Rats

        Yan Lan,Yan-Zhao Yang,Xian Jiang,Guang-Shi Jin,김민선,박병림,Yuan-Zhe Jin,Li-Wei Li 대한약리학회 2013 The Korean Journal of Physiology & Pharmacology Vol.17 No.4

        Contribution of the vestibular end organ to regulation of arterial pressure was quantitatively compared with the role of baroreceptors in terms of baroreflex sensitivity and c-Fos protein expression in the rostral ventrolateral medulla (RVLM). Baroreflex sensitivity and c-Fos protein expression in the RVLM were measured in conscious rats that had undergone bilateral labyrinthectomy (BL) and/or baroreceptor unloading. BL attenuated baroreflex sensitivity during intravenous infusion of sodium nitroprusside (SNP), but did not significantly affect the sensitivity following infusion of phenylephrine (PE). Baroreflex sensitivity became positive following sinoaortic denervation (SAD) during infusion of PE and attenuated sensitivity during infusion of SNP. Baroreflex sensitivity also became positive following double ablation (BL+SAD) during infusion of PE, and attenuated sensitivity during infusion of SNP. c-Fos protein expression increased significantly in the RVLM in the sham group after SNP administration. However, the BL, SAD, and SAD+BL groups showed significant decreases in c-Fos protein expression compared with that in the sham group. The SAD group showed more reduced c-Fos protein expression than that in the BL group, and the SAD+BL group showed less expression than that in the SAD group. These results suggest that the vestibular system cooperates with baroreceptors to maintain arterial pressure during hypotension but that baroreceptors regulate arterial pressure during both hypotension and hypertension. Additionally, afferent signals for maintaining blood pressure from the vestibular end organs and the baroreceptors may be integrated in the RVLM.

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