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      • KCI등재

        Comparison Study of the Band-gap Structure of a 1D-Photonic Crystal by Using TMM and FDTD Analyses

        Jian-Bo Chen,Yan Shen,Wei-Xi Zhou,Yu-Xiang Zheng,Hai-Bin Zhao,Liang-Yao Chen 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.58 No.42

        A variety of numerical methods has been developed to demonstrate the nature of photons propagating in an artificially-composed periodic structure. Differences will be generated by different kinds of numerical approaches. In this work, we carry out two types of numerical calculations, TMM (transfer matrix method) and FDTD (finite different time domain) calculations. In terms of the 1D-photonic crystal structures with two different structures, we illustrate the energy band spectra, and the results show dispersive characteristics for the optical transmission and reflection of the crystal material. Through a discussion of the mechanism, detailed comparison studies are preformed based on the different physical conditions. The results given in the work will help in better understanding the ways in which photons propagate in an artificially-composed periodic structure.

      • KCI등재

        EXPERIMENTAL RESEARCH ON EXHAUST THERMAL MANAGEMENT CONTROL STRATEGY FOR DIESEL PARTICULAR FILTER ACTIVE REGENERATION

        Jian Wang,Bin Wang,Zheng Cao 한국자동차공학회 2020 International journal of automotive technology Vol.21 No.5

        The regeneration was the main barrier restricting the development of diesel particulate filter (DPF), and the exhaust thermal management control strategy are the premise of efficient DPF active regeneration. This paper took a light vehicle equipped with high-pressure common rail diesel engine as the object, studied the influences of exhaust thermal management including intake throttling, fuel injection strategies and late post injection (LPI) coupling diesel oxidation catalyst (DOC) on exhaust temperature by experiment. The results indicated that the reduction of intake throttle valve opening at low speed and light load working conditions, where the exhaust temperatures were low, could dramatically increase the exhaust temperature. With a reasonable match of fuel injection parameters, the exhaust temperature could be increased. LPI coupling DOC could have a further increment on exhaust temperature, but it would have obvious negative effects on fuel economy and hydrocarbon emissions at the same time. In this paper, a comprehensive exhaust thermal management control strategy was proposed. The test bench indicated clearly that the demand of DPF regeneration temperature can be met in most working conditions through the reasonable integrated control strategies of exhaust thermal management.

      • Characteristics of Mammary Paget's Disease in China: a National-wide Multicenter Retrospective Study During 1999-2008

        Zheng, Shan,Song, Qing-Kun,Zhao, Lin,Huang, Rong,Sun, Li,Li, Jing,Fan, Jin-Hu,Zhang, Bao-Ning,Yang, Hong-Jian,Xu, Feng,Zhang, Bin,Qiao, You-Lin Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5

        The aim of this study was to detail characteristics of mammary Paget's disease (PD) representing the whole population in China. A total of 4211 female breast cancer inpatients at seven tertiary hospitals from seven representative geographical regions of China were collected randomly during 1999 to 2008. Data for demography, risk factors, diagnostic imaging test, physical examination and pathologic characters were surveyed and biomarker status was tested by immunohistochemistry. The differences of demography and risk factors between PD with breast cancer and other lesions were compared using Chi-square test or t-test, with attention to physical examination and pathological characters. The percentage of PD was 1.6% (68/4211) in all breast cancers. The mean age at diagnosis was 48.1, and 63.2% (43/68) patients were premenopausal. There is no difference in demography and risk factors between PD with breast cancer and other breast cancer (P > 0.05). The main pattern of PD in physical exam and pathologic pattern were patients presenting with a palpable mass in breast (65/68, 95.6%) and PD with underlying invasive cancer (82.4%, 56/68) respectively. The rate of multifocal disease was 7.4% (5/68). PD with invasive breast cancer showed larger tumor size, more multifocal disease, lower ER and PR expression and higher HER2 overexpression than those in other invasive breast cancer (P < 0.05). These results suggested that PD in China is a concomitant disease of breast cancer, and that PD with underlying invasive cancer has more multiple foci and more aggressive behavior compared with other breast invasive cancer. We address the urgent needs for establishing diagnostic and therapeutic guidelines for mammary PD in China.

      • KCI등재

        Seismic Behavior of Low-rise Concrete Shear Wall with Single Layer of Web Reinforcement and Inclined Rebars: Restoring Force Model

        Jian-Wei Zhang,Wen-Bin Zheng,Wan-Lin Cao,Hong-Ying Dong,Wan-Di Li 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.3

        In order to study the restoring force model of low-rise concrete shear wall with single layer of web reinforcement and inclined rebars, a series of specimens were investigated by quasi-static tests. Based on the fitting of experimental data and theoretical analysis, the restoring force model considering four characteristic points (crack point, yield point, peak point and failure point) and degradation of unloading stiffness was established. The hysteretic rule of restoring force model was determined by analyzing characteristic of hysteresis curve for cyclic loading tests. The results show that skeleton curves and hysteresis curves calculated by the restoring force model are in good agreement with the test curves, which can provide reference for the elastic-plastic dynamic analysis of low-rise concrete shear walls with single layer of web reinforcements and inclined rebars. Shaking table tests of two low-rise concrete shear walls were also conducted to investigate dynamic performance and the seismic damage mechanism of low-rise concrete shear wall with single layer of web reinforcement and inclined rebars. Research on dynamic nonlinear simplified model of SAP2000 shows thatthe proposed restoring force model can be used to analyze the elastic and elastic-plastic dynamic response for the low-rise concrete shear wall with single layer of web reinforcement and inclined rebars.

      • KCI등재

        Induction of Apoptosis by Chelerythrine Chloride through Mitochondrial Pathway and Bcl-2 Family Proteins in Human Hepatoma SMMC-7721 Cell

        Zheng-fu Zhang,Ying Guo,Jian-bin Zhang,Xiong-hui Wei 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.5

        The objective of this study was to evaluate the antitumor activity of chelerythrine chloride (CHE) and investigate its potential apoptotic induction mechanism in SMMC-7721 cells. Our results suggested that the proliferation of SMMC-7721 cells was inhibited by CHE in a time and dose dependent manner, with a significant accumulation in S phase, and the cells exhibited typical apoptotic features. Moreover, CHE remarkably induced apoptosis by disruption of the mitochondrial membrane potential, release of Cyt-c, activation of caspase-3, and cleavage of poly-ADP-ribose polymerase in a dose dependent manner. Furthermore, the expression of Bcl-xl was downregulated while Bax and Bid expression was upregulated, and no variation was found for Bcl-2. These results indicated that CHE may play an important role in suppression of tumor growth by inducing apoptosis in human hepatoma cells via the activation of a mitochondrial pathway and regulating the expression of Bcl-2 family proteins.

      • Analysis on Clinical Characteristics and Influencing Factors of Patients with Locoregionally Advanced Nasopharyngeal Carcinoma

        Zheng, Wei,Xu, Yuan-Ji,Qiu, Su-Fang,Zong, Jing-Feng,Huang, Ling-Ling,Huang, Chao-Bin,Lin, Shao-Jun,Pan, Jian-Ji Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.10

        Background: To explore the independent prognostic factors for the recurrence/metastasis of patients with locoregionally advanced nasopharyngeal carcinoma (LANPC). Materials and Methods: A total of 604 patients initially diagnosed as LANPC by pathohistology in Fujian Provincial Cancer Hospital were selected to analyze the relationship between the clinical pathological patterns, therapeutic protocols and clinical stages with the recurrence/metastasis of LANPC. Results: The 1-, 3- and 5-year locoregionally recurrent rates of LANPC patients were 2.0%, 9.5% and 12.9% respectively, with average recurrent period being 78 months. Univariate analysis results indicated that clinical stages had certain influence on the recurrent period of LANPC patients. However, COX regression models showed that ages, genders and clinical stages were not the independent prognostic factors influencing the recurrence. The 1-, 3- and 5-year metastatic rates of LANPC patients were 6.6%, 17.5% and 18.8% respectively, with average metastatic period of 73 months. Univariate analysis results demonstrated that ages, N stages, clinical stages, locations of lymph node, retropharyngeal lymph node and extracapsular invasion of lymph node had certain influence on the metastatic period of LANPC patients. Additionally, further COX regression analysis results suggested that T stages, reduction protocols and extracapsular invasion of lymph node were the independent prognostic factors influencing the metastasis of patients with LANPC, in which T stages and extracapsular invasion of lymph node were the pestilent factors while reduction protocols the protective factor. Conclusions: Induction chemotherapy is beneficial to LANPC patients with initial treatment, and the metastatic rate decreases greatly after the application of reduction chemotherapy.

      • KCI등재

        A Study on Autonomous Intersection Management: Planning-Based Strategy Improved by Convolutional Neural Network

        Jian Zhang,Xia Jiang,Ziyi Liu,Liang Zheng,Bin Ran 대한토목학회 2021 KSCE Journal of Civil Engineering Vol.25 No.10

        The development and application of autonomous vehicles bring great changes to urban traffic management and control. As one of the bottlenecks to improve transportation efficiency, intersection management plays an important role in the urban city. When the dynamic control method in different cases is determined, the key of autonomous intersection management problem is to search the passing orders for approaching connected and automated vehicles (CAVs). The paper proposed a framework based on convolutional neural network to predict different passing orders’ total time consumption. Thus, the best passing order with the lowest time consume can be chosen as the optimal solution. Then continuous-time optimal control can be carried out on CAVs. Meanwhile, sequential model-based algorithm configuration technique is used for neural network training. Simulation results exported from Simulation of Urban Mobility (SUMO) indicate that the proposed method outperforms actuated signal control and first come first serve strategy. The average delay of the proposed method can decrease by 42.40% − 73.05% compared with actuated signal control and 2.95% − 55.29% compared to first come first serve strategy. Moreover, it can increase average speed by more than 20% compared with the other two methods. The proposed method can significantly reduce the computation time comparing with the original planning-based strategy. At last, the framework can be applied to other regression tasks like vehicle emissions, then different optimization targets can be estimated to get better solutions faster.

      • KCI등재
      • KCI등재

        Triterpenoid Saponins from Elsholtzia bodinieri

        Hao-bin Hu*,Xu-dong Zheng,Huai-sheng Hu,Yu-feng Jian 대한화학회 2007 Bulletin of the Korean Chemical Society Vol.28 No.9

        A new oleanane-type triterpenoid estersaponin, bodinierin C (1), along with two known saponins, mazusaponin I (2) and ciwujianoside C (3), were isolated from the water-soluble part of the root barks of Elsholtzia bodinieri. The structure of bodinierin C was characterized by spectroscopic means and chemical hydrolysis as 3b -O-caffeoyl-23-hydroxylechinocystic acid 28-O-a -L-rhamnopyranosyl-(1 4)-b -D-glucopyranosyl-(1?6)-b -D-glucopyranosyl ester. The known compounds were identified by comparing their spectral data with those of authentic samples or data reported in the literature. All compounds were firstly isolated from Elsholtzia bodinieri family.

      • KCI등재

        Constituents of the Root of Anemone tomentosa

        Hao-Bin Hu,Xu-Dong Zheng,Yu-Feng Jian,Jian-Xin Liu,Ji-Hua Zhu 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.7

        A new diterpene glycoside, tomentoside I (1), along with eleven known compounds, including the four coumarins, 4,5-dimethoxyl-7-methylcoumarin (2), 4,7-dimethoxyl-5-methylcoumarin (3), isofraxidin (4) and fraxidin (5) as well as the seven triterpenoids, oleanolic acid (6), oleanolic acid 3-O-α-L-arabinopyranoside (7), oleanolic acid 3-O-β-D-galactopyranosyl-(1→3)-β-Dglucopyranoside (8), hederagenin 3-O-α-L-arabinopyranoside (9), betulinic acid (10), 18-hydroxyursolic acid (11) and 2α,3β,23-trihydroxyurs-12-en-28-oic acid (12) were isolated from the ethanolic extract of the root of Anemone tomentosa and their chemical structures were elucidated by spectroscopic methods. The antimicrobial activities of compounds 1-12 were measured using the agar disc-diffusion method. Also, their antioxidant activities against 1,1-diphenyl-2-picrylhydrazyl (DPPH) were evaluated.

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