http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
지역사회 재가노인의 우울과 건강행위와의 관계에서 분노표현 방식의 매개효과에 대한 성별차이
장미희 ( Mi Heui Jang ),이지아 ( Jia Lee ),김애실 ( Ae Sil Kim ) 한국간호과학회 정신간호학회(구 대한간호학회정신간호학회) 2014 정신간호학회지 Vol.23 No.1
Purpose: The purpose of this study was to identify the total, direct, and indirect influence of depression on health behavior (HB); to determine relative magnitudes of specific mediating effects of anger expression in gender specific subgroup among elders. Methods: A cross-sectional correlational survey was conducted in S and G cities with 333 community-dwe1ling elders (male=170, female=163). Data were collected from September 7 to November 7, 2013. Kee`s GDSSF-K for depression, Spielberger`s STAXI for anger expression and Choi & Kim’s health behavior assessment tool were used. Multiple-mediation analyses using Indirect SPSS macros were performed. Results: Depression had a significant total, direct and indirect effect on HB in both male and female. In women, direct and indirect effect of depression on HB were higher than in men. Specific indirect effects of depression on HB were evidenced via anger-control and anger-out for men and via anger-control and anger-in for women. Among anger expression, anger-control was a more salient mediator for both male and female. Conclusion: Findings suggest that depression and anger-control should be addressed in tandem for promotion of HB for elders. Tailored interventions for the promotion of HB should be developed considering gender of target population.
Kim, Hyeongmin,Ro, Jieun,Barua, Sonia,Hwang, Deuk Sun,Na, Seon-Jeong,Lee, Ho Sung,Jeong, Ji Hoon,Woo, Seulki,Kim, Hyewon,Hong, Bomi,Yun, Gyiae,Kim, Joong-Hark,Yoon, Young-Ho,Park, Myung-Gyu,Kim, Jia,S The Korean Society of Pharmacology 2015 The Korean Journal of Physiology & Pharmacology Vol.19 No.6
We investigated the combined moisturizing effect of liposomal serine and a cosmeceutical base selected in this study. Serine is a major amino acid consisting of natural moisturizing factors and keratin, and the hydroxyl group of serine can actively interact with water molecules. Therefore, we hypothesized that serine efficiently delivered to the stratum corneum (SC) of the skin would enhance the moisturizing capability of the skin. We prepared four different cosmeceutical bases (hydrogel, oil-in-water (O/W) essence, O/W cream, and water-in-oil (W/O) cream); their moisturizing abilities were then assessed using a $Corneometer^{(R)}$. The hydrogel was selected as the optimum base for skin moisturization based on the area under the moisture content change-time curves (AUMCC) values used as a parameter for the water hold capacity of the skin. Liposomal serine prepared by a reverse-phase evaporation method was then incorporated in the hydrogel. The liposomal serine-incorporated hydrogel (serine level=1%) showed an approximately 1.62~1.77 times greater moisturizing effect on the skin than those of hydrogel, hydrogel with serine (1%), and hydrogel with blank liposome. However, the AUMCC values were not dependent on the level of serine in liposomal serine-loaded hydrogels. Together, the delivery of serine to the SC of the skin is a promising strategy for moisturizing the skin. This study is expected to be an important step in developing highly effective moisturizing cosmeceutical products.
Chu, Jia-Qi,Kim, Su-Mi,Lee, Kwang-Nyeong,Oem, Jae-Ku,Ko, Young-Joon,Lee, Hyang-Sim,Kim, Yong-Joo,Park, Jee-Yong,Kim, Kwang-Jae,Parida, Satya,Oh, Yooni,Paton, David J.,Joo, Yi-Seok,Kim, Byounghan,Park, The Korean Society for Microbiology 2012 Journal of Bacteriology and Virology Vol.42 No.3
Interferon is an important cytokine that plays a critical role in the initial host defense against viral infection. Recombinant human adenoviruses expressing human interferon-${\alpha}$ (Ad-$HIFN{\alpha}$) or pig interferon-${\beta}$ fused with interleukin-18 (Ad-$PIFN{\beta}$-IL18) were constructed and used to induce an early protective response against foot and mouth disease (FMD). To analyze the antiviral effect, bovine thyroid and porcine kidney IBRS-2 cells and ICR mice were treated with Ad-$HIFN{\alpha}$, Ad-$PIFN{\beta}$-IL18, and cocktail of Ad-$HIFN{\alpha}$ and Ad-$PIFN{\beta}$-IL18. The survival rate of suckling mice was monitored after foot and mouth disease virus (FMDV) challenge following intra-peritoneal (IP) administration of appropriate adenovirus. Indirect antigen ELISA was performed to evaluate inhibition of FMDV replication following challenge with the FMDV O, A, or Asia 1 serotypes in vitro. These recombinant adenoviruses reduced the replication of FMDV in susceptible cells, thereby decreasing the fatality in mice, suggesting that they can be a useful control method for the early protection against FMD infection in livestock after field trial.
곽가려(Jia Li Guo),김순경(Soon Kyung Kim),김정원(Jeong Weon Kim),김미현(Mi Hyun Kim),김세나(Se Na Kim),김숙배(Sook Bae Kim) 대한지역사회영양학회 2013 대한지역사회영양학회지 Vol.18 No.6
The purpose of this study was to investigate the effects of nutrition education on nutrition knowledge, dietary attitude and dietary intake of Chinese college students in Korea. The subjects were 64 Chinese college students in Korea (educated group, 32 students vs. non-educated group, 32 students). Educated group was lessoned as group and/or individual. Nutrition education program consisted of four lessons (40min / lesson), ``6 major nutrients & function (group lesson)``, ``6 food group and sources (group lesson)``, ``personalized daily needed energy and food exchange units using Food Exchange System (individual lesson)``, and ``smart choice of snacks and eating-out foods (group lesson)``. We examined the differences between educated group and non-educated group in nutrition knowledge, dietary attitudes and nutrients intake. After education, there were positive improvements on nutrition knowledge: ``function and foods of 6 nutrients``, on dietary attitudes: ``type of breakfast`` in educated group. In the evaluation of nutrient intakes according to Dietary Reference Intakes for Korean (KDRI), there were positive improvements on intake levels of riboflavin, fiber, vitamin B6, vitamin C, folate, Ca and K in the educated group. In the index of nutrition quality (INQ), nutrition adequacy ratio (NAR) and mean nutrition adequacy ratio (MAR) were significantly increased in the educated group. In conclusion, it is possible to improve nutrition knowledge, dietary attitude and dietary intake of Chinese college students in Korea through the nutrition education focused on personalized daily needed energy and food exchange units.
Jia, Y.,Wu, C.,Kim, J.,Kim, B.,Lee, S.J. Butterworths ; Elsevier Science Ltd 2016 The Journal of nutritional biochemistry Vol.28 No.-
<P>We have previously reported that astaxanthin (AX), a dietary carotenoid, directly interacts with peroxisome proliferator-activated receptors PPAR alpha and PPAR gamma, activating PPAR alpha while inhibiting PPAR gamma, and thus reduces lipid accumulation in hepatocytes in vitro. To investigate the effects of AX in vivo, high-fat diet (HFD)-fed C57BL/6J mice were orally administered AX (6 or 30 mg/kg body weight) or vehicle for 8 weeks. AX significantly reduced the levels of triglyceride both in plasma and in liver compared with the control HFD mice. AX significantly improved liver histology and thus reduced both steatosis and inflammation scores of livers with hematoxylin and eosin staining. The number of inflammatory macrophages and Kupffer cells were reduced in livers by AX administration assessed with F4/80 staining. Hepatic PPAR alpha-responsive genes involved in fatty acid uptake and beta-oxidation were upregulated, whereas inflammatory genes were downregulated by AX administration. In vitro radiolabeled assays revealed that hepatic fatty acid oxidation was induced by AX administration, whereas fatty acid synthesis was not changed in hepatocytes. In mechanism studies, AX inhibited Akt activity and thus decreased SREBP1 phosphorylation and induced Insig-2a expression, both of which delayed nuclear translocation of SREBP1 and subsequent hepatic lipogenesis. Additionally, inhibition of the Akt-mTORC1 signaling axis by AX stimulated hepatic autophagy that could promote degradation of lipid droplets. These suggest that AX lowers hepatic lipid accumulation in HFD-fed mice via multiple mechanisms. In addition to the previously reported differential regulation of PPAR alpha and PPAR gamma, inhibition of Akt activity and activation of hepatic autophagy reduced hepatic steatosis in mouse livers. (C) 2015 Elsevier Inc. All rights reserved.</P>