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      • KCI등재

        저위교합된 제 2유구치에 대한 치험례

        곽소연,박기태,김지연 大韓小兒齒科學會 2009 大韓小兒齒科學會誌 Vol.36 No.3

        An infraoccluded tooth is a tooth that has failed to erupt to be in line with adjacent teeth in the vertical plane of occlusion. Multiple complications can occur as a result of an infraoccluded tooth. Tipping of neighboring teeth. loss of space opposing teeth elongation, increased susceptibility to dental caries and abnormal eruption path. impaction and rotation of permanent successor are the consequences of infraocclusion of primary molar. Therefore, early diagnosis and treatment is the key to prevent the complications. Treatment options can be periodic follow-up, temporary restoration or extraction of the infraoccluded tooth depending on the presence of the successor, the extent of infraocclusion and the extent of tilting of the neighboring teeth. The infraoccluded primary molars with permanent successors present tend to exfoliate normally. However, failure to do periodic check up of the infraoccluded teeth may lead to serious complications. In these cases, surgical extractions are often necessary after space regaining and space maintainers should be placed until the eruption of the permanent successors are completed. 저위교합이란 치아가 출온한 이후 유착 등의 원인으로 맹출이 정지되어 주위 인접치 보다 교합평면이 낮아지는 것을 말한다. 저위교합은 인접치들의 경사, 저위교합된 부위의 공간상실, 대합치의 정출, 해당부위 치아우식 감수성의 증가, 후속 영구치의 맹출경로 변위, 매복, 회전 등의 문제점을 유발할 수 있으므로 조기 진단 및 정기검진을 통한 적절한 치료가 필요하다. 저위교합된 유구치는 대부분 영구 계승치가 존재하며 일반적으로 정상 탈락한다. 그러나 저위교합된 유구치의 탈락이 지연되고 저위교합의 정도가 심화되어 해당부위의 공간상실이 발생하면, 공간부족으로 인하여 후속 영구치의 매복을 야기할 수 있다. 이러한 경우 교정적으로 공간확장술을 시행한 후 외과적 발치를 고려해야 한다. 본 증례는 하악 제 2유구치의 저위교합이 관찰된 3명의 환아를 대상으로 공간에 대한 평가 후 필요한 경우 공간확장술을 시행하고 발치를 시행함으로써 저위교합으로 인해 발생된 문제점을 개선하고, 추후에 발생될 합병증을 예방하였기에 이를 보고하는 바이다.

      • KCI등재

        성장기 쥐의 편측 교근에 주사한 보툴리눔 A형 독소가 하악골 성장에 미치는 영향

        곽소연,박기태,김지연 大韓小兒齒科學會 2009 大韓小兒齒科學會誌 Vol.36 No.3

        성장 시기가 다른 쥐의 편측 교근에 보툴리눔 A형 독소를 주사하여 하악골 성장에 미치는 영향을 알아보고자 하였다. 각기 다른 주령의 쥐(N=36, 1군: 4주령, 2군: 5주령, 3군: 6주령)를 대상으로 실험을 시행하였으며 각 군은 다시 대조군, 편측주사군, 양측주사군으로 나누어 하악골의 길이를 계측하고 다음과 같은 결과를 얻었다. 1. 1군에서 편측주사군의 주사측과 양측주사군 모두 하악체 길이, 과두 높이가 대조군 보다 낮은 값을 보였다(p<0.05). 2. 2군에서 편측주사군의 주사측과 양측주사군 모두 하악 전방부 높이와 과두높이에서 대조군 보다 낮은 값을 보였다(p<0.05). 3. 3군에서 편측주사군의 주사측과 양측주사군 모두 하악체 길이와 과두 높이, 과두돌기 높이가 대조군 보다 낮은 값을 보였다(p<0.05). 4. 세 군 모두 편측주사군의 양측 비교시 통계적으로 유의한 차이는 없었으나 주사측은 대조측 보다 낮은 계측값을 보이는 경향이 관찰되었다(p>0.05). The purpose of this study was to assess the effect on mandibular growth of botulinum toxin type A(BTXA) injection into the unilateral mass ester muscle of growing rats at three different growing stages. Thirty six male Sprague-Dawley rats were divided into three groups according to the age(group 1: 4 week-old, group 2: 5week-old, group 3: 6week-old). Then each group was randomly divided into 3 subgroups(control group, unilateral injection group, bilateral injection group). Experimental animals were sacrificed after 4 weeks. Then the jaw measurements were evaluated. The results were as follows: 1. In the group 1, mandibular body length, condylar height and coronoid process height of the unilateral group(BTXA side) and the bilateral group were shorter than those of the control group(p<0.05). 2. In the group 2, anterior region height, condylar height, coronoid process height of the unilateral group(BTXA side) and the bilateral group were shorter than those of the control group(p<0.05). 3. In the group 3, mandibular body length, condylar height, coronoid process height of the unilateral group(BTXA side) and the bilateral group were shorter than those of the control group(p<0.05). 4. There was no significant difference in mandibular measurements between the control side and the injection side in the unilateral group in all age groups(p>0.05).

      • KCI등재

        제1유구치의 조기 상실로 인한 공간 변화에 대한 3차원적 분석

        김지연,정다운,곽소연,유승은,박기태 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.2

        본 연구는 제1유구치의 조기 상실 시 공간 변화에 대한 분석을 위하여 3-Dimensional Laser Scanner를 이용하여 그 유용성을 평가하고자 하는 예비논문이다. 6세-8세 사이의 제1대구치가 맹출하여 확실한 교합 관계를 이루는 혼합치 열기 어린이 중 편측 제1유구치의 조기 발치가 필요한 6명의 발치 전 후의 모형을 이용하여 다음과 같은 결과를 얻었다. l. 유구치 공간변화는 상악은 실험군과 대조군 모두 현저한 감소를 보이지 않았고, 하악은 실험군에서 3명 중 2명에서 공간감소가 관찰되었다. 2. 치열궁 너비,치열궁 둘레는 초기모형과 최종모형에서 비슷한 값을 보였다. 3. 협설측 경사도 변화는 유견치에서는 상하악 모두 특별한 경향을 보이지 않았으며,제2유구치는 상악은 실험군과 대조군이 유사하였고,하악에서는 3명중 2명에서 실험군이 더 큰 설측경사도 변화를 보였다. 제1대구치는 하악에서 실험군이 더 큰 설측경사도 변화가 관찰되었다. 4. 근원심 경사도 변화 측정에서 유견치는 상하악 모두 특별한 경향이 관찰되지 않았고 제2유구치의 경우 하악에서 실험군이 더 큰 근심경사도 증가가 보였다. 제1대구치는 상악에서 실험군,대조군 모두 원심 경사도가 증가되었다. The purpose of this study was to evaluate a 3-Dimensional laser scanner for the space analysis after loss of a primary first molar. Six children with premature loss of a primary first molar were examined using study models taken before and after the extraction. The results were as follows: 1. There was no change in primary molar space after the extraction of a maxillary primary first molar However, 2 out of 3 children experienced primary molar space loss in extraction side of a mandibular primary first molar. 2. Arch width and arch perimeter showed no difference between initial and final model. 3. All primary canines did not show any changes in inclination. Maxillary primary second molars had similar changes in both extraction and control side. However, 2 out of 3 mandibular primary second molars in extraction side showed more lingual tipping compared to control side. Mandibular permanent first molars tipped more lingually in extraction side. 4. In angulation, primary canines showed nothing of significance. Mandibular primary second molars tipped more mesially in extraction side than in control side. Maxillary permanent first molars have increased distal angulation after extraction of primary first molars in both side.

      • KCI등재후보

        2009년 인플루엔자 대유행 중 인플루엔자 진료소 방문자의 연령 분포 변화

        김백남,곽이경,문치숙,김연숙,김의석,배인규,염준섭,이창섭,허지안 대한감염학회 2010 감염과 화학요법 Vol.42 No.2

        The pandemic influenza (H1N1 2009) virus, after being introduced in Korea in April, 2009, spread rapidly nationwide in mid-2009. This study was conducted to characterize trend in age distribution of visitors to Flu-clinics during the pandemic. Demographic, clinical and laboratory data of visitors to flu clinic from Week 36 to 52 (August 30 to December 26) of 2009 were retrieved and collected from electronic databases at 9 hospitals. Visitors 0-6, 7-12, 13-18, 19-29, 30-64, and 65 years or more of age were classified into group I to VI, respectively. A total of 107,467 visitors were seen at Flu-clinics for a 17-week study period. Of those, 32,485 were laboratory-confirmed. Antivirals were prescribed for 62,533 visitors. Numbers of visits, prescriptions of antivirals, and laboratory-confirmed cases of the pandemic influenza (H1N1 2009) peaked at Week 44. A large number of visits by group II and III were followed by those of group I and V, especially around the peak. Numbers of visits by group VI were lowest in all hospitals. In some hospitals, higher number of visits lasted longer in children than in adults while vice versa in other hospitals depending on the location. In summary, the pandemic influenza (H1N1 2009) was presumed to peak in late October and involved majorly children and students in Korea. Unique age distribution of visitors to flu clinic was observed in some hospitals.

      • Korean Association for Clinical Oncology : Slide Session ; OP4-1 : Others ; Target Sequencing of Papillary Renal Cell Carcinoma, Type 2, Using Custom-Made Kidney Cancer Panel

        ( Ji Yeon Kim ),( Se Hoon Lee ),( Jong Il Kim ),( Jong Yeon Shin ),( Kyung Chul Moon ),( Cheol Kwak ),( Hyeon Hoe Kim ),( Dae Seog Heo ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background:Papillary renal cell carcinoma type2 (PRCC2) has poor prognosis, treatment strategy is not established and the genetic alteration is poorly understood. We sequenced PRCC2 samples using custom-made kidney cancer panel to fi gure out genetic alterations of PRCC2. Methods: We have reviewed publications about the genetics of kidney cancer including all subtypes and selected 55 candidate genes. This cancer panel consisted of 1022 regions by Agilent SureSelect Target Enrichment. We sequenced 12 PRCC2 tumor samples along with 6 paired normal tissue samples. The patients` age were ranged from 26 to 82 year-old, and 3 patients were female (25%). Genomic DNA was isolated from dissected tumor tissue samples (6 fresh, frozen and 6 formalin-fi xed, paraffi n-embedded) and normal tissue samples. Sequencing was performed by Illumina platform and aligned to H. sapiens, hg19, GRCh37. Total probe number was 4103 and size was 283.494 kbp. Results: fifty-four of 55 target genes had 100% coverage, in spite of 92.7% coverage of one target gene. We found two novel FH mutations (one single nucleotide variant and one 5bp indel) and one novel NFE2L2 mutation. Two out of 12 samples (17%) were altered in NRF2 pathway (1 NFE2L2 and 1 KEAP) which was already well-known as driver in PRCC2. Novel PBRM1 mutation in two samples and SETD2 mutation in one sample were identifi ed. In addition, PTEN, TSC1, KDM5C and AKT1 mutation are observed in one case, respectively. No VHL mutation in PRCC2 was revealed. Conclusions: We analyzed somatic mutation of PRCC2 with custom-made kidney cancer panel. We found several candidate driver mutations of PRCC2. Our result reveals that the genetics of PRCC2 is heterogeneous, therefore, the approach using kidney cancer panel could be used to characterize individual PRCC2.

      • KCI등재

        A Study on Oral Health Awareness and Oral Health Behavior Factors for the Elderly over 65 in Some Areas

        Ji-Yeon Kwak,Cheon-Hee Lee 대한예방치과학회 2022 International Journal of Clinical Preventive Denti Vol.18 No.3

        Objective: Considering the need for oral health in the elderly, and analyzing factors and practices affecting the oral health of the elderly based on this, an in-depth theoretical review was conducted to analyze the factors affecting the oral health of the elderly on life in old age. Methods: The data collection for this study was conducted from October 7 to November 20, 2013 in Nowon-gu. People over 65 who visit local general hospitals, individual internal medicine clinics, and individual dental clinics. After explaining the purpose, content and purpose of this study to the elderly, consent. It is difficult to read the text as a questionnaire in a total of five structured chapters targeting only one person. The interview was conducted in the form of an interview in consideration of the characteristics. Results: As for the general characteristics of all respondents, in terms of gender, 29 male respondents (41.4%) and 41 female respondents (58.6%) were oral health perception factors, oral health behavior factors, and the meaning of life according to academic background. It was found that the higher the educational level, the more positive the perception of the meaning of life. Conclusion: Tooth brushing education and oral health education for preventive management of oral diseases. Policies and policies that enable the elderly related to health promotion to receive education easily and conveniently. It is necessary to find a method, and the accessibility of the medical period is also convenient to use. I should be able to get dental care easily.

      • KCI등재

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