일체형 완속교반/침전 그물망 압착식 섬유여과장치를 이용한 하수처리장 반류수 내 고농도 인 및 부유물질 처리

김정숙 ( Jeongsook Kim ),김민호 ( Min-ho Kim ),김미란 ( Mi-ran Kim ),장정국 ( Jeong-gook Jang ) 한국화학공학회 2017 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.55 No.6

하수 및 폐수 내 고농도의 인 및 부유물질 제어를 위해 개발한 일체형 완속교반/침전 그물망 압착식 섬유여과시스템을 이용하여 하수처리장의 반류수 내 부유성 고형물 및 인 처리에 적용했을 경우에 따른 성능을 검토하고자 하였다. 6가지 Mode로 실험을 하였으며, 16.7, 33.3, 41.7 및 50.0 ton/day 유량과 Al/P 몰비 2~4의 조건에서 실험을 행하였다. 응집제를 주입하였을 경우에 모두 높은 총인(T-P) 제거 효율을 보였지만 연속운전시간이 7.8 min~11.4 min으로 짧아지는 단점이 생겼다. 이를 극복하기 위해 일체형 완속교반/침전 그물망 압착식 섬유여과시스템을 응집/급속교반/공기주입/완속교반/침전공정 및 여과공정으로 진행 시 연속운전시간이 88.2 min으로 다른 모드로 운전한 결과에 비해 8~11.3배 정도 증가하였다. 역세수량율도 5.4%로 매우 낮게 나타남에 따라 이 공정이 가장 효율적인 처리방안으로 평가되었다. An integrated slow mixing/sedimentation and net fit fiber filtration system has been developed to reduce the high concentrations of suspended solid (SS) and total phosphorus (T-P) in the reject water from sewage/wastewater. A filtration device used in this experiment consists of coagulation, in-line mixing, air injection, slow mixing/sedimen-tation, and filtration processes. The performance test using this device was carried out with six operational modes for reject water from sewage treatment plant. Experimental conditions used were 16.7, 33.3, 41.7 and 50.0 ton/day of flow rate and 2~4 of Al/P molar ratio. By injection of coagulant in each operational mode, the high removal efficiencies of SS and T-P were obtained, but continuous operation time was decreased to 7.8~11.4 min in most modes. However, when the Mode 5 of the developed filtration device was applied, the continuous operation time was maintained up to 88.2 min. Also, it was found that the continuous operation time in the Mode 5 using the developed system was increased from 8 to 11.3 times longer than those in other modes. Backwashing flow rate was also very low at 5.4% of total filtered water. Therefore, it can be concluded that the Mode 5 of the developed filtration system was the most efficient treatment method for the removal of high concentrations of SS and T-P.

Aerobic exercise training enhances cell proliferation and reduces IL-2 and IL-6 cytokine production in spleen of high fat diet-induced obese mice

( Hee Geun Park ),( Deog Jo Jung ),( Jun Hyun Jeong ),( Jong Kui Jun ),( A Ram Yoon ),( Young Ran Lee ),( Kyung Eun Min ),( Myung Hwa Kim ),( Kwang Moo Lee ),( Wang Lok Lee ) 한국운동영양학회 2013 Physical Activity and Nutrition (Phys Act Nutr) Vol.17 No.1

This study investigated the effect of aerobic exercise training on immune cell proliferation and inflammatory cytokine production in the spleen of high fat diet-induced obese mice. C57B1J6 male mice (4 weeks aged. n20) were fed a high fat diet (45% fat) for 5 weeks so that obesity was led intentionally. Then, these obese mice were divided into 2 groups: control group (CON. n10) or exercise group (EXE, n=l0). EXE performed treadmill running for 30-60 min/day at 10-22 m/min, 0% grade, five times per week for 8 weeks. After 13 weeks, all the splenocyte was collected and Con A (Concanvalin A 10 ㎍/ml) was used to stimulate the cell proliferation. MTS and BIOPLEX assay were used for cell proliferation and cytokine production. Independent t-test was used and a p-value under 0.05 was considered as statistically significant. In the results, body weight, IL-2 and IL-6 production were significantly reduced and Splenocyte proliferation was significantly increased after 8 weeks of exercise training. These findings suggest that aerobic exercise training has a positive effect for improving the obese-induced immune dysfunction.

[P239] A case of recurrent acute paronychia

( Min Seok Hur ),( Joo Ran Hong ),( Hye In Cheon ),( Song Hee Han ),( Byung Gon Choi ),( Hae Jeong Youn ),( Min Jung Kim ),( Yang Won Lee ),( Yong Beom Choe ),( Kyu Joong Ahn ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

While acute paronychia is usually caused by bacterial infection, chronic paronychia is a multifactorial inflammatory disease of the nail apparatus due to irritants and allergens. Recurrent acute paronychia may evolve into chronic paronychia. A 23-year-old female was referred to our dermatologic clinic with an erythematous and edematous proximal nail fold of right forth finger. She had been treated with nail extraction and antifungal agent in the diagnosis of acute paronychia due to bacterial and fungal infection. The lesion seemed to be improved but aggravated with abscess formation. We drained pus and carried out wound culture and KOH smear, but we could not get pathogenic findings. We tried cefadroxil and nonsteroidal anti-inflammatory drugs with nail extraction. Despite of repeated treatments, her problem didn’t seem to be improved. For management of recurrent acute paronychia, we decided to add anti-pseudomonal agent to previous treatment. The lesion has kept improved state without relapse. We report an interesting case of recurrent acute paronychia refractory to treatment with antibiotics, antifungal agents and surgical management.

Erratum: Isolation and characterization of canine umbilical cord blood-derived mesenchymal stem cells

Min-Soo Seo,Yun-Hyeok Jeong,Jeung-Ran Park,Sang-Bum Park,Kyoung-Hwan Rho,Hyung-Sik Kim,Kyung-Rok Yu,Seung-Hee Lee,Ji-Won Jung,Yong-Soon Lee,Kyung-Sun Kang 대한수의학회 2009 Journal of Veterinary Science Vol.10 No.4

[P220] A case of multiple basal cell carcinoma in xeroderma pigmentosum treated with CO₂ laser and ingenol mebutate gel

( Min Seok Hur ),( Joo Ran Hong ),( Hye In Cheon ),( Song Hee Han ),( Byung Gon Choi ),( Hae Jeong Youn ),( Min Jung Kim ),( Yang Won Lee ),( Yong Beom Choe ),( Kyu Joong Ahn ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Xeroderma pigmentosum (Xp) is a rare autosomal recessive disorder of DNA repair, with a prevalence of 1 in 1 million individuals. It is characterized by extreme sensitivity to sunlight, resulting in sunburn, pigment changes in the skin, a high incidence of skin cancer, and developmental disorders. A 12-year-old girl presented with multiple scaly patches of various sizes and nodules on her face. Histological diagnosis revealed basal cell carcinoma. In addition to the malignancy, she had a pigmentaryabnormality, hypersensitivity to sunlight, neurological hearing loss, intellectual deficiency, and developmental delay. In accordance with the symptoms and findings, she was clinically diagnosed as having Xp. We used carbon dioxide laser to treat the malignant lesions and treated the other small scaly papules with 0.015% ingenol mebutate gel to prevent cancer related to Xp. Herein we report a case of early onset skin cancer occurring in a patient with severe form of Xp.

Soft Magnetic Composites: Basics and Methods to Minimize Core Loss

Min-Sun Jang,Bonuk Koo,Jong-Min Park,Hea-Ran Kim,Young-Tae Kwon,Sangsun Yang,Jae Won Jeong 한국자기학회 2021 한국자기학회 학술연구발표회 논문개요집 Vol.31 No.2

Soft magnetic composite (SMC) which can produce an innovative 3-dimensional core has been much attraction as the potential in various electrical machinery fields because of their superior soft magnetic properties such as a high magnetic permeability and a low core loss at a high frequency range. In general, SMC is composed of Fe-based ferromagnetic particles, and the surface of the iron particles is covered with an inorganic or organic insulation layer. It is possible to improve the surface resistance and thus form an insulated space between them, which can remarkably reduce the eddy-current losses. SMC is generally used as a part of a machine, but in the case of some electric machines, the need for developing high-strength SMC parts is being raised against the material is damaged by fatigue due to exposure to continuous vibration or external shock. There is a method to develop high-strength SMC by the densification of the surface insulating materials through annealing at high temperature (600 °C~1000 °C). However, in general, there is a disadvantage in that insulation is weakened after annealed at high temperature, so an evaluation is necessary to secure both strength characteristics and insulation coating layer retention. Herein, SMC with different inorganic coating materials which is well-known to withstand at high temperature; SiO₂, MgO, and PO₄ and stacking layer; mono or double parameters have been considered for magnetic characterization. All of the coated iron particles were prepared by a chemical sol-gel method, and the thickness of the formed coating layer was confirmed to be 500-600 nm on average through a scanning electron microscope and an energy dispersive X-ray spectrometer. Based on the excellent insulating layer condition (i.e. mono-layers and double-layers, @SiO₂@MgO and @MgO@SiO₂), the core loss evaluation were conducted at high temperature (> 600 °C). Toroidal cores with an outer/inner diameter of 25/15 mm and a thickness of 3 mm were manufactured by cold pressing under a pressure of 500 MPa and then annealed for 1 h at 600 °C, 700 °C, 800 °C, and 900 °C, respectively, in Ar atmosphere to figure out the retention of insulation layer. As a result, as the annealing temperature increased, the core loss with phosphating layer rapidly increased at 1 kHz and 1T because it was carbonized and lost above 650 °C. As compared to the phosphating layer, on the other hand, the SMCs coated with SiO₂ or MgO or double layers annealed at 800 °C exhibited higher retained flux density as well as a significantly low increasing rate of core loss as the frequency and external magnetic field strength increased (at 0.05~1 kHz and 0.3~1 T). This work might be offered a noticeable ideal to design inorganic insulation layer for SMC applications under the high temperature atmospheres.

Comparison of Virucidal Efficacy of Disinfectant Ingredients Against Foot-and-Mouth Disease Virus

Jeong Ran Min,Sang Hee Jeong,Young Won Kim,Hye Sook Lee,Jong Ho Kim,Hyung keun Kwak 대한수의학회 2012 대한수의학회 학술대회발표집 Vol.2012 No.-

HCC : PE-056 ; Change of cytokine profile following transarterial chemotherapy in patients with hepatocellular carcinoma

( Min Ju Kim ),( Jeong Won Jang ),( Jung Hyun Kwon ),( Chan Ran You ),( Nam Ik Han ),( Chang Don Lee ),( Hyun Suk Jung ),( Dong Wook Jekarl ),( Seung Ok Lee ),( Kyu Won Chung ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1

Background: Although alterations in cytokine profile after therapy can affect the outcome and prognosis of cancer patients, there are no comprehensive data on multiple cytokine profiles during transarterial chemotherapy (TACE). Methods: Cytometric bead immunoassay was used to simultaneously measure 13 cytokines (interleukin [IL]-12p70, IFN-γ, IL-17A, IL-2, IL-10, IL-9, IL-22, IL-6, IL-13, IL-4, IL-5, IL-1β, and TNF-α) in the sera of 83 patients with hepatocellular carcinoma (HCC) and 18 healthy controls. Those cytokines were serially monitored at baseline, day 3, day 7, and 2 months after TACE in 63 evaluable patients. Results: Serum levels of IL-17A and IL-5 were higher in HCC patients than healthy controls, whereas IL-22 and IL-1β levels were lower in HCC patients. Although the overall patterns of cytokine changes were diverse at each set date, certain cytokines specifically increased after TACE, with the early-phase increase in IL-6 and IL-22 levels and late-phase increase in IL-4, IL-6, and IL-10 levels. With relatively minor changes of cytokines after TACE, Childs B/C group had higher IL-6 and lower IL-22 levels than Childs A group. Patients with larger tumors (>5 cm) had higher IL-6 levels at baseline and showed a transient but significant early-phase increase in IL-6 levels as well as late-phase increase in IL-4, IL-10, and IL-13 levels after TACE. With regard to hepatic events, IL-2 and IL-22 levels at baseline were predictive of grade 3 or more hepatic toxicity, while those levels of IL-6 and IL-13 significantly increased at day 3 in patients suffering from post- TACE hepatic morbidity. Conclusions: TACE induces various changes of multiple cytokines. Distinct panels of cytokine changes are not uniform, influenced by treatment-induced inflammation, underlying liver function, and HCC stage. The increased Th2 cytokine profiles after TACE suggests the immune suppression in patients with large tumor and post-treatment hepatitis.

Kidney Toxicity Induced by 13 Weeks Exposure to the Fruiting Body of Paecilomyces sinclairii in Rats

Jeong, Mi-Hye,Kim, Young-Won,Min, Jeong-Ran,Kwon, Min,Han, Beom-Suk,Kim, Jeong-Gyu,Jeong, Sang-Hee Korean Society of ToxicologyKorea Environmental Mu 2012 Toxicological Research Vol.28 No.3

Paecilomyces sinclairiis (PS) is known as a functional food or human health supplement. However concerns have been raised about its kidney toxicity. This study was performed to investigate the kidney toxicity of PS by 13 week-oral administration to rats. Blood urea nitrogen (BUN), serum creatinine, and kidney damage biomarkers including beta-2-microglobulin (${\beta}2m$), glutathione S-transferase alpha (GST-${\alpha}$), kidney injury molecule 1 (KIM-1), tissue inhibitor of matrix metalloproteinase 1 (TIMP-1), vascular endothelial growth factor (VEGF), calbindin, clusterin, cystatin C, neutrophil gelatinase-associated lipocalin (NGAL) and osteopontin were measured during or after the treatment of PS. BUN, creatinine and kidney damage biomarkers in serum were not changed by PS. However, kidney cell karyomegaly and tubular hypertrophy were observed dose-dependently with higher severity in males. KIM-1, TIMP-1 and osteopontin in kidney and urine were increased dose dependently in male or at the highest dose in female rats. Increased urinary osteopontin by PS was not recovered at 2 weeks of post-exposure in both genders. Cystatin C in kidney was decreased at all treatment groups but inversely increased in urine. The changes in kidney damage biomarkers were more remarkable in male than female rats. These data indicate that the PS may provoke renal cell damage and glomerular filtration dysfunction in rats with histopathological lesions and change of kidney damage biomarkers in kidney or urine. Kidney and urinary KIM-1 and cystatin C were the most marked indicators, while kidney weight, BUN and creatinine and kidney damage biomarkers in serum were not influenced.

Amphetamine-Like Weight Reduction Drug Induced Acute Cardiomyopathy with Left Ventricular Thrombosis

Jeong Min Kim,Sung Kee Ryu,Jae Woong Choi,Dong Geum Shin,Yung Hee Lee,Hye Ran Kang,Won Young Chae,Ji Sang Park 이화여자대학교 의과학연구소 2014 EMJ (Ewha medical journal) Vol.37 No.S

Obesity has become one of the main health issues, and various attempts to reduce weight have been tried. Many people take drugs that suppress appetite and the absorption of food and increase the metabolic rate. However, some of these drugs have unpredictable complications, including cardiovascular side effects. Some legally marketed amphetamine-like drugs such as fenproporex and diethylpropione are also prescribed for weight reduction for their appetite reduction effect, but these drugs share the side effects of amphetamines [1]. There are multiple reported cases of acute myocardial infarction and stroke after the use of amphetamines [2-10]. However, to our knowledge there are no published case reports of intracardiac thrombosis with an amphetamine-like drug without myocardial infarction. We report the case of a 37-year-old female presenting with a left ventricle (LV) thrombus after amphetamine intake.