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      • 비만증 환자에서 한약제에 의한 체중 감소효과

        Oh, Seung-Joon,Jeong, In-Kyung,Kim, Young-Seol,Choi, Young-Kil,Paeng, Jeong-Ryung,Bae, Jung-Hwan,Shin, Hyun-Dae 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

        Seung-Joon Oh, In-Kyung Jeong, Young-Seol Kim, Young-Kil Choi, Jeong-Ryung Paeng¹, Jung-Hwan Bae and Hyun-Dae Shin²Department of internal Medicine, College Medicine, Endocrine Research Institute¹. Department of Rehabilitation, College of Oriental Medicine², Seoul, korea. Bady Fat Reduction Effects of Red Ginseng Compound Preparation on the Patients with Obesity. Proceedings of International Symposium on East-West Medicine, Seoul. 244-254, 1999.-Obesity can be defined as a metabolic disease due to an increased state of fat tissues caused by an imbalance of calorie intake and use. Recently, in Korea by improvement and westernization of food intake, along with decrease in exercise activities, the prevalence of obesity has increased greatly. Our objectives were to study stability and effects of decrease in body fat by administering red ginseng compound preparation (known to have body fat decreasing effects in laboratory animals) to obesity patients on low calorie diets. Changes in weight and body fat were measured while carrying out calorie-restricted diets on patients for 4 weeks, then administering red ginseng compound preparation for another 4 weeks. The patients were 20 people whose BMI were 25kg/㎡ or over and whose percent body fat was also 30% or over when tested by bioelectrical conductivity. 1. Changes in weight were from 70.04kg(base line) to 67.43kg(after taking red ginseng compound preparation). 2. In similar sense, BMI decreased from 27.12kg/㎡(base line) to 26.56kg/㎡(after dieting), and further to 26.01kg/㎡ (after taking red ginseng compound preparation). The BMI seemed to decrease significantly compared to the baseline after the use of red ginseng compound. 3. Waist hip ratio was changed from 0.8858(base line) to 0.8728, but it was statistically insignificant. 4. The percent body fat was 35,16%(base line), 33.87%(after dieting), and 31.68%(after taking red ginseng compound preparation). 5. Complete blood cell count and blood chemisrty remained unaffected by the administration. 6. In concern to endocrinologic studies, T3 decreased from 118.7 to 98.2ng/dL, and T4 increased from 8.8 to 9.2㎕/ dL. Epinephrine showed a tendency to decreased from 0.27 to 0.25 ng/mL, and norepinephrine increased from 0.39 to 0.44ng/mL. 7. Leptin was not changed. 8. Some patients complained adverse effects; constipation(5 patients, may be due to diet therapy), fatigue (2 patients), pruritus(2 patients), flushing(s patients), dizziness(3 patients) and epigastric discomfort(2 patients). However their symptoms were mild, so medication did not stopped. In conclusion, loss of weight without significant side effects was observed during low calorie diet and red ginseng compound preparation administration. This is thought to be in relation to sympathetic nerve system rather than adrenal gland. Also, further long0term studies should be required, since the observed results were based on short-term changes in weight.

      • 흡연에 의한 급성 호산구성 폐렴 2예

        박종빈,김학렬,주현준,유태양,신성남,신정현,송정섭,황기은,김소영,양세훈,정은택 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.2

        최근 흡연을 시작한 젊은 성언에서 급성 호산구성 폐렴의 발생에 대한 증례가 보고되고 있다. 급성 호산구성 폐렴은 대개 발열을 동반하기 때문에 초기에는 감염성 폐렴으로 잘못 진단, 치료되는 경우가 많다. 아직 정확한 병태 생리 및 조직학적 소견은 밝혀져 있지 않지만 병력 청취 및 임상 양상, 방사선 소견의 관찰을 통해 급성 호산구성 폐렴을 의심하고, 진단을 위해 기관지 폐포 세척액 검사를 시행한다면 좀 더 쉽게 진단 내릴 수 있을 것이다. 본 저자들은 최근 처음 시작한 흡연에 의해 발생한 급성 호산구성 폐렴을 진단하고, 스테로이드를 투여하여 성공적으로 치료한 환자 2예를 경험하였기에 이를 문헌 고찰과 함께 보고하는 바이다. Acute eosinophilic pneumonia(AEP) is characterized by acute febrile respiratory illness associated with diffuse pulmonary infiltration and pulmonary eosinophilia. The specific etiology for acute eosinophilic pneumonia is elusive. By some investigators, cigarette smoking is suggested as a causative substance which can cause AEP. In recent, the authors experienced two cases of AEP following cigarette smoking. Both cases had characteristic features including age around 20 years, new onset smoking before occurance of AEP, diffuse infiltration on chest radiography, pulmonary eosinophilia based on bronchoalveolar lavage and acute improvement after steroid therapy. These clinical features are resemble with previous smoking induced AEP case reports. Base on these clinical features, cigarette smoking associated AEP could be diagnosed more easily.

      • 한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

        양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

        The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

      • 국소 폐병변에서의 역동적 조용증강 CT의 유용성

        신현준,최영철,전혜정,박정희,김요한 건국대학교 의과학연구소 1998 건국의과학학술지 Vol.8 No.-

        The blood supply and metabolism of malignant nodules are qualitatively and quantitatively different from those of most benign nodules. We evaluated the efficacy of dynamic CT for differentiation of benign malignant lesions. Thirty-six patients with malignant nodule(n=20), tuberculoma(n=7), and pneumonic consolidation(n=9) were evaluated by thin section dynamic CT. CT numbers of lesion and aorta were measured before enhancement, and 1 minute, and 3 minutes after enhancement. Malignant lesions(maximum, 31.1±10.7 HU) enhanced significantly more than tuberculoma(maximum, 13.5±12.9 HU), but mass/aorta ratios were not so significantly different between malignant lesions(maximum, 0.61±0.27), tuberculoma(maximum, 0.36±0.15), and pneumonic consolidation(maximum,0.49±0.14). Dynamic CT is very useful for differentiation of malignant lesions from tuberculoma.

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        헤밍웨이 인물들의 "위험한 선택"

        신정현 서울大學校 人文學硏究所 2003 人文論叢 Vol.49 No.-

        Hemingway's life and work has often been interpreted as a typical expression of American tradition of escapism. This interpretation would not be wrong; on the contrary, it enlightens his reader on the complex cultural background of his death-oriented plot. His protagonists, without exception, try to escape from everyday reality of culture by indulging in outdoor activities such as fishing, participating in war, watching bullfighting, safari hunting, etc. Indeed, they have no effective relationships with "cultured" sorts, struggling to discover themselves in the more primitive dimension. Hemingway's best works including The Sun Also Rises, Farewell to Arms, For Whom the Bell Tolls, and The Old Man and the Sea are all among the finest and most outspoken pieces of that variety in American Literature. Another trend of interpretation focuses on the pshychic state of Hemingway heroes. The psychic trauma inflicted by the World War I, which was not a play but an unknowable violence itself, was conjured and relived in Hemingway's novels over and over again. It is possible that Hemingway can be envisaged as a psychiatrist who diagnoses his own mental and emotional disorders incurred by the war and project them into his works. His characters are, in one aspect, all "war patients" in Freudian sense, who have sufferred a severe wound, obeying the so-called "repetition compulsion," and dreaming a masochistic dream. It can be told that as a means of adjusting to the neurosis, Hemingway's heroes repeat the experience of death and violence endlessly. However, the thematic circle of these two interpretations can be enlarged when they are projected to the more universal current of 20th-century Western thought - existentialism - whose appeal lay mainly in its ability to reflect the experience of violence, atrocity, and alienation brewed in the 20th-century European civilization. In the post-World War I years, it began to grip the imagination of many thinkers, writers, and artists; and Hemingway belonged to the crew of the lost generation. Like other existentialist writers, Hemingway speculates in his works about the nature of reality, subordinating traditional metaphysical questions to an anthropocentric perspective, in which there takes place a tragic confrontation between man and the world. Especially like Camus, he regards human existence as unexplainable and the world man inhabits as hostile and indifferent, and stresses freedom of choice and responsibility for the consequences of one's acts. When read chronologically, Hemingway's novels constitute an existential myth in which characters present their own tragic vision of life in the mechanized modern inhuman world. From the very beginning, his use of the existential absurd becomes a metaphysical device to explore the incomprehensible modern existence. In the earlier works, Hemingway's alter ego named Nick learns about the nihility of the life in the existential void from his "code hero" who admits freedom, patience, courage, choice, and responsibility as their own "codes." In due course of growth, Nick grows out of learning into maturity. In For Whom the Bell Tolls, Robert Jordan can appreciate the tragic world into which he was "thrown" so that he declares, "The world is a fine place and worth the fighting for. ..." The Old Man and the Sea is a perfect coda of Hemingway's existential myth. Here the sphere of the myth is expanded into social dimension where sympathy can play an existential role for "a man not to be defeated even though destroyed." The essential "doctrine" of Hemingways works is that life consists of futility, agony, and dread that can be overcome only by "courage" and "persistence." As in other existentialists' world, in Hemingway's world, freedom, even if it exists, is dreadful, deprived of confidence and entailing agony and dread. Thus, Hemingway's own sense of "elegance" is a cosmic irony about the existence in the world thoroughly divested.

      • 에스테르류에 의한 2-프로판올의 액-액 추출에 관한 연구

        鄭詳勳,申鉉心,朴東源 동아대학교 공과대학 부설 한국자원개발연구소 1995 硏究報告 Vol.19 No.2

        The experimental binodal curves and tie-line data were determined for ternary systems of 2 propanol-water with ethylacetate, butylacetate and isoa-mylacetate as solvents at 25℃, and those tie-line data were used to examine thermodynamic consistency. The experimental tie line data were correlated with UNIQUAC and modified UNIQUAC model and the parameters in each model and the calculated values of tie line were predicted. The distribution and selectivity curves in the equilibrium of ternary systems were determined to find the extraction effect.

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        업무 관련성 견갑상 포착 신경증이 의심되는 3례

        정두신,성기범,신현길,안무영,김형수,홍영의 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.4

        Objectives : Entrapment of the suprascapular nerve is frequently overlooked in the differential diagnosis of shoulder pain. Methods : Suprascapular entrapment neuropathy is a well-defined clinical entity and EMG and NCV is used to confirm a diagnosis. But the diagnosis typically not considered until patients develop severe weakness secondary to atrophy of the spinous musculature that the nerve supplies. Results : A narrow suprascapular notch has rarely been reported as a work-related factor of this entrapment neuropathy. Diagnosis of suprascapular entrapment neuropathy is based on the patients' clinical course, neurologic, radiologic, and electrophysiologic findings. One of the most helpful evaluations was anteriorposterior projection with the X-ray tube angled 15-30 degree caudally. The suprascapular entrapment neuropathy is relatively uncommon entity of shoulder discomfort(pain, weakness, and atrophy). Conclusions : If the worker who used his shoulder joint repetitiously having the shoulder pain and muscle weakness, we must rule out the suprascapular entrapment neuropathy. And it is needed to evaluate the motions which cause suprascapular entrapment neuropathy as the ergonomic factor.

      • 최근 5년간 피부외과술로 치료받은 환자의 분석 : 1994. 1∼1998. 12

        신정현,강민정,조소연,황규광,함정희 梨花女子大學校 醫科大學 醫科學硏究所 2000 EMJ (Ewha medical journal) Vol.23 No.2

        연구 목적 : 1990년대 이후 국외 및 국내에서 피부외과의 영역이 넓어지고 있으나 현재 국내에서 시행되고 있는 피부외과적 수술에 대한 통계는 아직 보고되지 않아 그 현황이 잘 파악되지 않고 있다. 이에 저자들은 본교실 미용피부외과 클리닉에 내원하여 수술을 받은 환자 1,075명을 대상으로 통계적 분석을 시행하여 피부외과 환자의 분포, 경향을 파악하여 향후 발전의 토대로 삼고자 한다. 방법: 1994년 1월부터 1998년 12월까지 5년간 이화여자대학교 의과대학 부속 동대문병원 피부과 미용피부외과 클리닉에 내원하여 수술을 받은 환자 1,075명을 대상으로 성별, 연령별, 주거지역별 분포와 진단명 및 수술의 종류에 대하여 통계적 분석하였다. 결과: 1) 남녀비는 1 : 2.4였고, 연령은 10개월부터 87세까지로 다양하였으나 20, 30대가 66.0%로 가장 많고 평균연령은 남자 30.6세, 여자 30.2세였다. 환자의 주거지역별 분포는 서울시가 75%로 가장 많았고 서울시내 지역구별의 차이는 크지 않았다. 2) 환자 1명이 두 가지 이상의 질환을 가질 때 각 질환을 개개로 간주하여 총 1.354예의 질환을 수술하였으며 반흔(39.8%), 색소성 질환(30.8%), 악성/양성종양(21.2%), 기타질환(8.2%) 순이었다. 3) 수술은 총 2,334회 시행되었고 그 종류별 빈도는 화학박피수술 가장 많아 846예(36.2%)이었고 다음으로 냉동외과술 650예(27.8%), CO_2 레이저 255예(10.9%), 기계박피술 209예(8.9%), 외과적 절제술 113예(4.8%), Mohs 미세도식수술 61예(2.6%), 혈관응고술 50예(2.1%), 피판재건술 48예(2.0%)이었으며 그 외 모발이식 15예, 표피이식 13예, 자가지방이식 2예 등이 있었다. 4) 각 반흔의 종류에 따라 분류하면, 여드름반흔은 화학박피술(72.7%), CO_2 레이저(11.9%) 및 기계박피술(9.7%)로, 위축성반흔은 기계박피술(37.3%). CO_2 레이저(27.8%) 및 펀치상향술(11.9%)로, 비후성반흔은 냉동외과술(28.2%), 기계박피술(24.2%) 및 CO_2 레이저(22.7%)로 치료하였다. 5) 악성종양 및 일부 양성종양에 Mohs 미세도식수술을 시행하였으며 재건술로 총 61예 중 피판재건술을 시행한 예가 가장 많아 45.9%이었고, 단순봉합이 36.1%, 복합봉합은 18.0% 이었다. 결론: 피부외과적 수술환자는 여자가 남자보다 2.4배 많았으나 남자의 비율이 증가추세에 있고 남녀 모두 평균 연령은 30대였다. 수술질환은 반흔과 색소성 질환이 가장 많아 미용적인 관심이 매우 높음을 알 수 있었고 연도별 유의한 차이는 없었다 총 2,334회 수술 중 화학박피술, 냉동외과술이 50% 이상을 차지하였고 반흔의 종류에 따라 선호되는 수술이 달랐다. 악성종양은 모두 Mohs 미세도식 수술하였으며 주로 국소 피판술로 재건하였다. 이상의 분석으로 피부외과적 수술환자의 분포, 대상질환, 수술방법 등을 빈도별로 파악할 수 있었으며, 향후 각 질환별 혹은 수술별로 세분하여 수술성과 및 만족도 조사를 시행함으로써 피부외과 분야 및 본 크리닉의 발전 방향을 설정하는 가늠자 역할을 할 것으로 기대한다. Background : The field of dermatologic surgery has seen trementdous developments in the past few years. Objective : Our purpose was to discuss current statistical data on the dermatologic patients treated by surgical methods at our institute. Methods : We analyzed 2,334 cases of surgeries performed on 1,075 patients at the Department of Dermatology of Ewha Womans University Tongdaemun Hospital during a period of 5 years (1994. 1 - 1998. 12). Results & Conclusion : The results are summarized as folows: 1) Of the 2,334 cases of surgeries, 846 cases(36.2%) were chemical peelings, 650 cases(27.8%) cryosurgeries, 255 cases(10.9%) CO_2, lasers, 209 cases(8.9%) dermabrasions, 113 cases(4.8%) scalpel surgeries, 61 cases(2.6%) Mohs micrographic surgeries, 50 cases(21.1%) sclerotherapy, 48 cases(2.0%) flap repair surgeries, 35 cases(1.5%) punch elevations, 15 cases(0.6%) hair transplantations, 13 cases(0.5%) epidermal grafts, and 2 cases(0.1%) autologous fat/collagen transplantations. 2) The ratio of male to female was 1 : 2.4 and the mean age of patients was 30.3 years. 3) A total of 1,354 cases of diseases were managed surgically : among them, the most frequent disease was scar(39.8%), followed by pigmentary disorders(30.8%), and benign or malignant tumors(21.2%). 4) With respect to the types of scars, acne scar was treated most frequently by chemical peeling (72.7% of 580 cases), atrophic scar by dermabrasion(37.3% of 126 cases), and hypertrophic scar (including burn scars) by cryosurgery(35.3% of 85 cases).

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