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      • 차별화 서비스에서 공정한 대역폭 보장 방안

        정충교,유용수 강원대학교 정보통신연구소 2000 정보통신논문지 Vol.4 No.-

        It has been observed that assured service in the differentiated service network cannot guarantee the contracted profile rate fairly. Achieved throughput depends on the profile rates. TCP's congestion avoidance algrorithm causes this. In this paper we proposed 3-drop precedence scheme which is using token bucket and TSW(Time Sliding Window) marker to solve this problem. we showed proposed scheme improves the performance of assured service and this scheme is effective also when the non-responsive UDP traffic sources exist.

      • γ-Alumina에 담지된 산화구리에 의한 SO_2의 제거에 관한 연구

        鄭一鉉,尹龍水,全法柱 단국대학교 1992 論文集 Vol.26 No.-

        In the case of SO_2 removal from the flue gases by fixed beds of coper oxide in two types or γ-Aluminas with different pore size distribution, the reactive sorption capability were correlated with not only porosity and pore size distribution in the reacting solid but impregnated concentration of the reacting solid but impregnated concentration of the copper oxide. The effect of change of pore structures on the kineticc of gas-solid reaction was investigated through the random pore model. Mathematical model og gas-solid noncatalytic reaction for the concentration vs. time relationship in corporating chemical reaction, product layer diffusion, and the effect of structural change due to chemical reaction has been derived. Numerical solution were obtained to the model equations for various values of the parameters characterizing the pore structure, effective internal diffusion, and the chemical reaction constant. From the results, the conversion was decreased cause of pore closure at the surface of reactiong particles, reduction of porosity and surface area of reaction, and increase of effective diffusion coefficient in the solid with the progress of reaction, Conversion was increased with rised concentration of flue gas since that CuO-SO_2 reaction mechanism assumed to be first order. Total conversion was strongly dependent on the local conversion at surface. According to decreas of impregnated concentration of the copper oxide and increase of the flue gases concentration, total conversion was increased. The conversion was affected by gas flow rate and pore size distribution in the reacting solid.

      • KCI등재

        Genome-wide investigation of a Korean synthetic breed, Woori-Heukdon using the Illumina PorcineSNP60K BeadChip

        Yong‑Min Kim,Ha‑Seung Seong,Jung‑Jae Lee,Da‑Hye Son,Jin‑Su Kim,Soo‑Jin Sa,Young‑Sin Kim,Tae‑Jeong Choi,Kyu‑Ho Cho,Joon‑Ki Hong,Jung‑Woo Choi,Eun‑Seok Cho 한국유전학회 2020 Genes & Genomics Vol.42 No.12

        Background: Woori-Heukdon (KWH) is a Korean synthetic pig breed generated using Chookjin-Duroc (KCD), Chookjin-Chamdon (KCC), and their crossbreds. Currently, there is a severe lack of studies investigating the Korean breed populations including wild boars (KWB) throughout the genome. Objective: This study was performed to investigate the genetic characteristics of Korean pig populations at the genome-wide level. Methods: Using the SNP dataset derived from genotyped and downloaded datasets using the Illumina PorcineSNP60K BeadChip, we compared the genomes of 532 individuals derived from 23 pig breeds to assess the genetic diversity, inbreeding coefficient, genetic differentiation, and population structure. Results: KWB showed the lowest average expected heterozygosity (HE = 0.1904), while KWH showed the highest genetic diversity (HE = 0.02859) among Korean populations. We verified that the genetic composition of KWH, showing USD of 74.8% and KCC of 25.2% in ADMIXTURE analysis. In population structure analyses, KCC was consistently shown to be separated from other pig populations. In addition, we observed gene flow from Western pigs to a part of Chinese populations. Conclusion: This study showed that Korean native pigs, KCC have genetic differences in comparison with Chinese and Western pigs; despite some historical records and recent genetic studies, we could not find any clear evidence that KCC was significantly influenced by Chinese or Western breeds in this study. We also verified the theoretical genomic composition of KWH at the molecular level in structure analyses. To our knowledge, this is the first genomic study to investigate the genomic characteristics of KWH and KCC.

      • KCI등재후보

        『元生夢遊錄 』의 문학적 이해와 역사 담론

        정용수 한국한문교육학회 2003 한문교육논집 Vol.21 No.-

        「원생몽유록」은 최근까지 작자와 작품에 대한 논란이 계속되고 있는 작품 이다. 이러한 문제는 현전하는 이본이 무려 20편 이상이라는 데 있을 것이다. 간혹 선본을 정하고 작품 이해를 종합적으로 검토하려는 노력도 있었지만, 언제 누구에 의해 창작되었는지 정확한 정보를 갖고 있지 못하는 우리로서는 현재의 정보가 원천적으로 한계를 지닐 수밖에 없고,더 중요한 것은 창작 이후 생성된 여러 이본들의 역사적 의미를 놓치게 될 공산이 크다는 점이다. 이런 점에서 「원생몽유록」의 이해에 있어 중요한 점의 하나가 우선, 이 작품을 문학적으로 이해하려는 안목과 역사적 변모과정에서 산생된 담론의 의미를살피는 작업일 것이다. 필자는 이 작품이 여러 번에 걸쳐 변개가 있었던 점을 염두에 두고, 적어도 이 작품의 이해에 있어 작품 변개의 요인이 된 역사적추이를 걷어내고 이해하기란 어렵다는 입장을 갖고 있다. 따라서 본고에서는 이런 단계적 변모에도 바뀌지 않은 기본축을 중심으로 작품 속의 주요 쟁론과 각몽 이후의 에필로그에 첨가된 내용을 살펴보고자 하는 것이다. 그리하여 최초 창작 이후 역사적 사건이나 개인적 이해에 따라 다양하게 변모된 작품양상을 어떻게 이해할 것인가에 초점을 두었다. 그 결과,이 작품은 작자 원호가 계유년 사건을 몽유 양식을 차용하여 문학적으로 형상한 것으로 보았다. 그래서 작자는 등장인물을 당시 사건 관련자에서 찾아 소설적 기교로써 활용하였고,당대 담론을 폭건자를 통해서 형상했다는 것이다. 이 작품에서 우리는 작품 밑바닥에 깔려있는 두 가지 서사적 탠션(tension)을 읽을 수 있다. 육신처럼 역사현상을 회고할 수밖에 없는 역사 인물군이 하나 있다면,여지껏 역사현상보다 현재 자신들의 감정을 발설하는 실존인물군이 있음을 알 수 있다. 두 인물군 중에서 자신들의 감정을 발설하는 실존 인물군이 세조 왕위찬탈의 문제를 꿈으로 형상했다고 보아야만이 찬탈자들을 향해 <狐媚取禪>,<以臣伐君>의 효시라는 평가와 일치되지 않겠는가.이미 해금을 논하는 과정에서 <호미취선>,<이신벌군> 같은 지나간 용어를 사용했다는 말은 논리에 맞지 않을 뿐더러, 이후 조정공론은 사륙신에 대한공적 평가였지 세조에 대한 불의 평가가 아니었고 또한 용납되지도 않았다는 점을 참고할 필요가 있다. 이런 점에서 이 작품은 사륙신의 절의를 나타냈다기보다 세조의 불의를 폭로한 생육신 원호의 세계관을 형상한 것이 되야 하며,그런 작가에 의해 그려진 극도의 소설적 미학으로 보아야 한다는 것이다. 따라서 세조가 왕위를 찬탈한 직후,부각되기 시작된 사군의 논쟁을 소설 속의 인물 폭건자를 통해서 형상한 작품이 「원생몽유록」이라면,세 가지 형태의 부기된 四君論爭의 역사 담론과 이본 생성은 창작 이후 계유년 사건과 육신에 대한 역사적 평가를 추가한 것에 불과하다고 보는 것이다. There has been constant controversy concerning Wonsaeng-mong-yurok and its author up to recently. It is believed that the controversy results from a great number of its different versions. The number is said to be over 20. Occasionally efforts to understand synthetically after deciding the old version have been made, but they have met some difficulties due to the limit of information on when and by whom it was produced. Furthermore, it is more likely than not that they miss the historical significance of its different versions which had been produced after the creation of its original version. In this respect, one of the most important things for understanding Wonsaeng-mong-yurok is to investigate the meaning of its discourse that were made in the changing process of its history with an appreciative eyes for the understanding of Wonsaeng-mong-yurok in its literary perspective. A firm belief is that it is difficult to understand the work without a close study on its historical change after due consideration of its many changes. Therefore, this study aims to investigate the main argumentation and the contents that were added to its epilogue after being awakened from the hero's illusions with special reference to its underlying points that were never altered in the changing process. In addition, it focuses on how to understand the aspects of the work that underwent a variable alteration in accordance with the historical events and the personal interests in it after the first appearance. As a result of this research, some points can be concluded as follows: first, Wonsaeng-mong-yurok was written by Wonho as a literary work in the form of dream, which represents a historical incident in the year of Kyeyu. He chose persons who were related to the incident at that time and used them as characters and created a contemporary discourse skillfully through a despot. It can be seen that two kinds of narrative tension can be read on the bottom. One is the group of historical characters who couldn't help recalled the past to their mind like Yukshin(Six Subjects), and the other is a group of real characters who expresses their own feelings instead of historical phenomena. Among them, it is believed that real characters described the issue of usurping a throne of King Sejo into a dream story. Because this views can agree with the fact that the usurpers were evaluated as the pioneer of homichwiseon and ishinbeolgun. There is necessity of considering that it is incoherent to use the old fashioned terms such as homichwiseon and ishinbeolgun in the process of discussing the removal of a ban and that consensus in the court then was not for the injustice of King Sejo, but for Saryukshin(six loyal subjects who willingly submitted to death. Accordingly, this work shows not so much Saryukshin's fidelity to their own principles as Wonho's world views who tried to disclose the unforgivable injustice of King Sejo, and must be highly regarded as a prosaic aesthetics. In conclusion, Wonsaeng-mong-yurok describes the argumentation of Sagun (four kings) right after usurping a throne of King Sejo through a violent character in the novel and it is believed that three types of historical discourse concerning a controversy of Sagun that were added to its original version and its different versions include a historical evaluation of the incident in the year of Kyeyu and Yukshin after its appearance.

      • KCI등재후보

        奎章閣所藏 古本 『剪燈新話句解』의 板本 硏究

        정용수 한국고소설학회 2002 古小說 硏究 Vol.14 No.-

        이 글은 「전등신화구해」의 현존 최고본으로 알려진 일본 내각문고본을 통해서 초간 목판본인 규장각소장 고본 「전등신화구해」가 존재한다는 사실을 밝힌 글이다. 근거로 내각문고본에서 두 가지 형태의 판심제가 존재하고, 같은 판심제 중의 하나가 규장각본에 나타난다는 사실을 확인한 것이다. 결국 내각문고본이 임란 이전 간본이 분명하다면 두 자료 중 하나는 초간본에 해당되고 나머지 하나는 중간본에 해당되는 것이므로, 규장각본이 내각문고본의 선행본으로 확인된다는 것은 규장각본이 초간본임을 말한 것일 뿐 아니라 내각 문고본이 중간본임을 의미하게 되는 것이다. 이 점은 임기의 발문이나 이미 발견된 윤춘년 발문을 통해서도 확인된다. 즉, 우리나라에서 주석한 「전등신화구해」는 최초 주석본으로 목활자로 간행된 송분 간본이 있었고, 이어 목판본으로 간행된 초간본으로서 윤계연이 1559년 간행하고 임기가 주석한 간본이 있었으며, 다음으로 복각본으로서 윤춘년이 간행했거나 주도하여 1564년 간행하고 임기가 주석한 간본이 존재했음을 확인하게 된 것이다. 이번에 조선초기 간행된 이 목판본 들을 확인하게 된 것이다. 양본의 판심제 '新話句解' 및 '新話'는 임란 이전 간본을 바탕으로 한 것이므로, 임란 이후 간본에서는 나타나지 않는 현상이다. 「전등신화」는 현재 알려진 임란 이전 간본이 다소 있는 듯이 보이지만, 「전등신화구해」는 윤계연과 윤춘년 간본 밖에 없었던 것이 분명하다. 또한, 내각문고본을 보판복각본으로 추정함녀서 이것이 윤춘년에 의해 복각된 간본으로 추정하였다. 그래서 두 본 사이의 이동이 거의 같을 수 밖에 없었던 것으로 본 것이다. This is to prove that the first edition of Jeondungshinhwa-goohae printed from wood blocks exists in Kyoojang-gag by investigating the Japanese Naegakmungo edition well known as the oldest edition of Jeondungshinhwa-goohae. This results from the comparison of its two editions and publication before Hideyoshi's invasion of Korea in 1592. This study owes the existence of the Japanese edition which was published before 1952. The two editions of one book mean the existence of its precedent edition, which makes it certain that the old book in Kyoojang-gag is the first edition printed from wood blocks. The bibliographical notes on the old book in Kyoojang-gag, as told earlier, enable both editions to be considered the first edition and the second edition. Besides, Songboon edition printed from wood blocks as the first notes on Jeondungshinhwa-goohae, its publication as printed from wood blocks before 1952, makes sure that there existed the 1559 Yimki commentary edition by Kye-hyun Yoon and the 1564 Yimki commentary edition by Choon-nyeon Yoon. Panshinje in the Kyoojang-gag edition and the Naegakmungo edition are depended upon the edition before 1592, and after that time on it disappeared. It might be guessed that some editions of Jeondungshinhwa before 1592 were, but that no editions of Jeondungshinhwa-goohae existed except the Kye-hyun Yoon's and Choon-nyeon Yoon's. They are the existing Kyoojang-gag edition and Naegakmungo edition, The Naegakmungo edition might be translated by Choon-nyeon Yoon on the basis of Kye-hyun Yoon's first edition with Yimki's commentary. Therefore, it can be said that there has been a similarity between the two editions.

      • KCI등재
      • 기존 골조공사공법과 복합화구조공법의 작업생산성 및 공사비 비교분석에 관한 사례연구

        김정재,박옥근,김용수 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1

        The purpose of this study is to provide productivity(man-hour) and cost comparison among conventional structural methods(Reinforced concrete structure and Steel structure) and new structure methods(HI-Beam and LC-Frame) in office buildings. Productivity and cost analysis were performed based on data collection in construction sites and interview survey. The results of this study are as follows: comprehensive productive and cost efficiency is investigated as high from (1)LC-frame, (2)HI-Beam, (3)steel structure, and reinforced concrete in order.

      • KCI등재

        혼합치열기의 miniscrew를 이용한 교정치료

        임수민,양연미,김재곤,백병주,이용훈,신정근 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.2

        Anchorage plays an important role in orthodontic treatment, Skeletal anchorage like the miniscrew is considered a more effective method in anchorage control than conventional anchorage which needs much patient s cooperation. The miniscrew offers many advantages. 1) It is easy to insert and to remove. 2) It can endure the force needed for moving teeth. 3) It can be immediately loaded and 4) Patient cooperation is not needed. 5) It is economic compared to other skeletal anchorage systems, In comparison to adult's bones, children s bones have comparatively poor bone quality and quantity. Therefore, it is hard to obtain primary stability in younger patients. However, if the miniscrew can be retained successfully, it will be effective in many orthodontic treatments. In these cases we used the miniscrew in correcting of diastema, in aligning dental midline, and in rendering a forced eruption of impacted tooth in mixed dentition patient. We obtained satisfactory results. 교정치료 시 고정원은 항상 염두에 두면서 치료를 진행해야 하는 중요한 요소이다. 전통적인 고정원을 이용한 치료는 환자의 적극적인 협조를 필요로 하고 원하는 치아이동에 대한 반작용이 나타날 수 있는 등의 부작용을 가지고 있다. 그러므로 보다 견고한 구강 내 고정원이 요구되어져 왔으며 이를 위해 miniscrew가 임상에서 흔히 이용되고 있다. Miniscrew를 통한 고정원의 확보는 구외력 의존도 감소,치료기간의 단축,식립 후 즉시 교정력 적용,환자의 협조도 불필요,식립의 간편성,저렴한 비용 등의 장점을 가지고 있다. 그러나 성장기 환자는 성인에 비해 골질이 좋지 않아 miniscrew의 성공률이 성인에 비해 낮다. 그러나 일단 고정에 성공하면 많은 교정치료 시 매우 유용하게 이용할 수 있다. 본 증례는 흔합치열기 환자를 miniscrew를 이용하여 정중이개 및 정중선 불일치,매복치에 대한 양호한 교정치료를 하였기에 보고하는 바이다.

      • KCI등재

        양극성 장애에서 표피성장인자의 유전적 다형성에 대한 연합연구

        김수경,이규영,주은정,강웅구,안용민,김용식 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.6

        Objectives : Epidermal growth factor (EGF) is a neurotrophic factor which regulates the intracellular signaling molecules. These molecules are also affected by mood stabilizers such as lithium and valproate. In addition, epidermal growth factor enhances neuronal survival, maturation and differentiation especially in midbrain dopaminergic neurons of which dysfimction may play a role in pathophysiology of bipolar disorders. Bipolar disorder has some genetic commonalities with schizophrenia, and several association studies of EGF have been done with schizophrenia. In this study, we tried to investigate the geneticassociation between EGF A61G polymorphism and bipolar disorder. Methods : Total of 189 patients and 347 nonnal control were included. All patients satisfied the diagnostic criteria of DSM-IV for bipolar disorder type I (BPDI, N= 146) and bipolar disorder type II (BPDII, N=43). Genomic DNA was extracted from the peripheral blood, and genotyping was performed by TaqMan™ method. Genotype and allele frequency of EGF A61G polymorphism between the patients and the control were compared by contingency chi-square test or the Fisher's exact test. Results : No association was found between EGF A61G polymorphism and susceptibility of BPDI, BPDII and bipolar disorder (all patients). Female patients with BPDII showed overexpression of AG genotype compared to that ofcontrol group (p=0.03). However, this association was not significant after correction of multiple testing. Conclusion : In conclusion, EGF A61G polymorphism has no association with susceptibility of bipolar disorder. However, the disease modifying role of EGF gene polymorphism for bipolar disorder remains to be elucidated in respect to factors such as gender difference or diagnostic subtype.

      • 다제 내성 폐렴구균에 대한 항균제 병합시의 시험관내 항균효과

        김수정,이남용,양지원,백경란,김성민,배직현,송재훈 대한감염학회 1997 감염 Vol.29 No.2

        목적: 페니실린 및 다제 내성 폐렴구균은 선택할 수 있는 치료제가 제한되어 임상적으로 문제가 되고 있다. 특히 다제 내성 균주에 의한 수막염의 치료에 cephalosporin제 단독요법의 치료 실패가 계속 보고 되면서, 기존 항균제의 병용요법이나 새로 개발되는 항균제에 관심이 모아지고 있다. 특히 국내에서 분리되는 폐렴구균의 페니실린 및 다제 내성율은 이미 세계 최고 수준으로 이러한 치료법의 개발이 더욱 필요한 상황이다. 저자들은 다제 내성 폐렴구균 감염증의 새로운 치료법을 찾고자 국내에서 흔히 사용되는 항균제를 대상으로 time-kill 방법을 이용한 시험관내 synergy 여부를 알아보고자 하였다. 방법 :대상균주는 국내에서 분리된 페니실린 감수성인 2균주와 모든 β-lactam 제제에 동시 내성을 보인 다제 내성 5균주이었다. 대상 병용요법은 penicillin+gentamicin, cefotaxime+gentamicin, vancomycin+gentamicin, vancomycin+cefotaxime, vancomycin+imipenem, ampicillin+cefotaxime 등이었다. 각 항균제의 시험 농도는 1/2 MIC로 하였으며, 균 집락수의 측정은 0,4,8,24시간에 시행하였다. 결과:Penicillin+gentamicin, cefotaxime+gentamicin, vancomycin+cefotaxime 등의 병합요법이 시험관내 synergy를 보였으며, vancomycin+gentamicin, vancomycin+imipenem, ampicillin+cefotaxime 등의 병용은 indifference의 결과를 보였다. 결론 본 연구를 통하여 penicillin+gentamicin, cefotaxime+gentamicin, vancomycin+cefotaxime 등의 병용요법이 다제 내성 균주에 대하여 시험관내 synergy를 보임으로써 새로운 치료요법의 대상이 될 수 있음을 확인하였다. 또한 이는 향후 생체 내에서의 약물 상호작용에 대한 동물실험시 응용될 수 있는 기본 자료로 의미가 있을 것으로 생각된다. Background: Penicillin-and multidrug-resistant Streptococcus pneumoniae became a global problem during recent decades. Multidrug resistance poses a serious threat to clinical medicine due to restriction of selecting appropriate antimicrobial agents to treat with. Current data suggest that any single antimicrobial agent cannot be a satisfactory option to treat pniemococcal infections caused by multidrug-resistant strains, particularly in meningitis. The aim of the study was to assess in vitro efficacy of several antimicrobial combinations which are commonly used in clinical practice, and to obtain reasonable regimens which can be applied to in vivo model. Methods: We performed time-kill studies of antimicrobial combinations including penicillin, cefotaxime, vancomycin, gentamicin, imipenem and ampicillin against five multidrug-resistant strains and two penicillin-susceptible strains. Penicillin, cefotaxime and vancomycin were combined with gentamicin, respectively. Cefotaxime plus vancomycin, imipenem plus vancomycin, and cefotaxime plus ampicillin combinations were also tested. Synergy was defined as a ≥100-fold or 2-log decrease in colony count at 24 h by the combination compared with that by the most active single agent. Result: Penicillin puls gentamicin, cefotaxime plus gentamicin, and vancomycin plus cefotaxime combinations were deminstrated to have in vitro synergistic activities against multidrug-resistant strains. Conclusion: Three combinations showed in vitro synergism against penicillin-resistant pneumococci. Experimental animal study is warranted to determine the clinical relevance of the in vitro results.

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