열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

벼 밭재배에 따른 수량 및 미질

최원영,최민규,김상수,이규성,김태수,이재길 한국국제농업개발학회 2003 韓國國際農業開發學會誌 Vol.15 No.4

벼 밭재배시 논벼 품종들의 적응성을 검토하기 위하여 마늘 간작으로 벼를 건답점파하여 재배한 결과를 요약하면 다음과 같다. 1. 입모율은 밭벼에 비해 논벼 품종이 낮았는데 그 순서는 상남밭벼〉동진찰벼〉신선찰벼〉진부찰벼 순이었다. 2. 출수기는 상남밭벼에 비해 진부찰벼는 3일 빨랐고 신선찰벼는 9일, 동진찰벼는 12일이 늦었다. 3. ㎡당 수수와 등숙비율은 밭벼에 비해 논벼품종들이 높았다. 4. 쌀수량은 상남밭벼에 비해 신선찰벼는 12%가 많았고 동진찰벼는 같았으며, 진부찰벼는 18%가 적었다. 5. 완전립비율은 진부찰벼에서 높았고 그 외는 비슷하였으며, 식미지수는 상남밭벼에 비해 동진찰벼는 높았으나 진주찰벼와 신선찰벼는 낮았다. To identify the rice varieties adaptable for upland cultivation, a series of experiments was carried out at the field(Chonnam series) of the Muan. Cheonnam province during 1999 - 2001. Four varieties, Jinbuchalbyeo(early-maturing variety), Sinseonchalbyeo (medium-maturing variety), Dongjinchalbyeo(medium-late maturing variety), and Sangnambatbyeo as a standard variety for upland were used in this experiment. Seedling establishment of the varieties was the highest in Sangnambatbyeo and followed by Dongjinchalbyeo under upland condition. Heading date in general delayed ranges from 9 to 12 days, while early-maturing variety, Jinbuchalbyeo was faster for 3 days compared with Sangnambatbyeo. Number of panicle per square meter was similar in both lowland and upland rice but percentage of ripened grain was high in lowland rice. Milled rice yield was high as of 12% in Sinseonchalbyeo compared with Sangnambatbyeo. Head rice ratio showed also the highest in Sinseonchalbyeo. The results indicate that Sinseonchalbyeo as glutinous rice variety could adapt well in this upland condition, and have good milling recovery as head rice as well as yield advantage.

傾斜地 테라스하우스에서 유형과 경사각도에 따른 密度에 관한 硏究

최규학,이재훈 대한건축학회 2004 대한건축학회논문집 Vol.20 No.10

This study analyzes the dwelling-density through house units-type and the slope-angle from the terrace house complex on slope-site The results are summarized as follows 1) The increase of the floor area ratio concerns with the slope-angle of the site In low slope-angle, it has little difference between combination type, but the more the site incline the more the difference increase In same size of building area, slope-angle and combination-type, floor area ratio of the compact '-' units-type increase more maximum 25%, compared with the 'ㄱ' units-type 2) The building coverage subordinate to the combination-type, the selected units-type and combination-type turn up almost regularly in all inclination 3) The open space ratio per floor area influenced by the slope-angle of the site Inclining, the open space ratio per floor area decreases and so the open space of the house unit, too It is shown, that the difference between types in low inclined slope-sites are bigger than the ones in high inclined slope-sites

요고가와 吸蟲 및 肝吸蟲의 疫學的 調査 : 耽津江流域을 中心으로

최신철,문재규,정요한 조선의대 1984 The Medical Journal of Chosun University Vol.9 No.1

다발성 간종괴의 형태로 나타난 특발성 과호산구 증후군 치험1예

최승오,연규민,이승민,김순제,왕준호,박형석,이재동,진춘조,이창훈,신현준,김정은 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-

Hypereosinophilic syndrome is characterized by persistent blood eosinophilia of 1,500/ul or more in the absence of known causes and multiorgan dysfunction by eosinophil-related tissue damage. In Korea, some cases of hypereosinophilic syndrome with hepatic involvement have been described with prolonged benign clinical courses. Most of them were diffuse or multifocal lesions in imaging studies, and a few case presenting as a single mass has been described. Here we report a case of hypereosinophilic syndrome with hepatic involvement in a 65-year-old man who presented with multifocal mass lesions. By abdominal US and CT scan, multiple, ill-defined nodules were detected in throughout the liver. Liver biopsy revealed severe eosinophilic hepatitis, suggestive of hypereosinophilic syndrome. Hepatic mass lesions improved after steroid administration for several weeks.

Monochlorophenol의 목질분해균에 의한 분해 특성

최인규,이재원,최돈하 한국환경농학회 2002 한국환경농학회지 Vol.21 No.4

onochlorophenol인 2-, 3- 및 4-chlorophenol에 대해서 D. contentrica, T. versicolor, P. ostreatus 3균주를 이용하여 저항성, 분해능, 분해산물 등을 비교 분석하였다. T. versicolor는 monochlorophenol의 종류 및 농도의 증가에 따라 전혀 영향을 받지 않고 균사 생장이 이뤄지며, D. contentrica는 3-, 4-chlorophenol에서 100 ㎎/L 이상으로 농도가 증가하면 균사 생장이 느려져 제한을 받고 있는 것으로 나타났다. P. ostreatus는 두 균주와 달리 대조구 자체의 생장이 14일 정도로 상당히 느렸으나 2-, 3-chlorophenol을 첨가했을 때 오히려 1~2일 정도씩 생장이 촉진되는 결과를 나타냈다. 2-Chloro- phenol 이나 3-chlorophenol에서는 P. ostreatus가 제일 우수한 분해능을 보였으며 4-chlorophenol의 경우는 T. versicolor가 2균주에 비하여 월등하게 우수하게 나타나 균주가 따른 mono- chlorophenol의 분해능에 있어서 차이가 있고, 염소의 치환 위치에 따라 ortho나 meta 보다는 para위치에 염소가 치환된 4-chlorophenol이 D. contentrica나 P. ostreatus의 경우 분해가 느린 것으로 나타났다. 그러나 T. versicolor는 2-, 3- 및 4-chlorophenol의 저항성 시험에서 균사 생장이 제한을 받지 않고 우수한 생장력을 갖고 있는 것처럼 분해능 시험에 있어서도 우수하였다. 균주별로 pH와 균사량은 P. ostreatus > T. versicolor > D. concentrica 순으로 높았으며, 균주내에서 배양일수별로 pH의 변이는 유동적이었고 균사량은 조금씩 증가하였으나 뚜렷한 차이는 없었다. 즉, 2-, 3- 또는 4-chlorophenol의 목질분해균을 이용한 분해에 있어서 pH 및 균사량은 monochlorophenol 의 분해능과는 상관관계가 낮은 것으로 나타났다. T. versicolor 와 P. ostreatus의 경우는 높은 laccase의 유도 효과를 나타내면서 monochlorophenol의 분해에 영향을 주는 것으로 생각된다. monochlorophenol의 분해산물로는 1,3,5-trihydoxyl benzene, 1-ethyl-1-hydroxyl pentane, 2-pro-penoicacid, methylmalonic acid, 2-methyl-4-keto-pentan-2-ol 등과 지방산의 일종인 tetradecanoic acid, hexadecane, hept-adecanoic acid, octadecanoic acid 등이 확인되었다. Biodegradation of monochlorophenols by wood rot fungi such as Daldina concentrica, Trametes versicolor and Pleurotus ostreatus was evaluated by determining their resistance or toxic test and biodegradability. The metabolites of monochlorophenols were also analyzed. Among the three fungi, T. versicolor was the most resistant to 200 ppm of 2-, 3- and 4-chlorophenols, and did not show any inhibitory mycellium growth. But D. concentrica had a little inhibition effect at more than 100 ppm of 3- or 4-chlorophenol. Control cultures of P. ostreatus took even 14 days for the completion of mycellium growth, but the hyphal growth was improved when 2- or 3-chlorophenol were added to the culture. In biodegradation analysis, P. ostreatus showed the highest degradation of 2- or 3-chlorophenol, while T. versicolor was the most effective in 4-chlorophenol. D. contentrica and P. ostreatus slowly degraded 4-chiorophenol. However, T. versicolor had similar degradation capability in the three monochlorophenols, suggesting that the biode- gradation mode is dependent on the fungi as well as the type of monochlorophenol. Several metabolites such as 1,3,5-trihydroxyl benzene, 1-ethyl-1-hydroxyl pentane, 2-propenoicacid, methylmalonic acid and 2-methyl-4-keto-pentan-2-ol were found as products of primary oxidation of 2-, 3- and 4-chlorophenols by intact fungal cultures. Fatty acids including tetradecanoic, heptadecanoic and octadecanoic acids were also detected. The order of increase of mycellium weight during incubation were P. ostreatus > T. versicolor > D. concentrica. The pH in the culture was not constantly changed depending on incubation days, but the mycellium weight was slightly increased, indicating that the biodegradation of monochlorophenol night have low relationship with the mycellium growth. Laccase activities of T. versicolor and P. ostreatus were continuously increased depending on the incubation days, suggesting that the ligninolytic enzyme activity play an important role in the biodegradation of monochlorophenol.

절충연산자를 이용한 다목적 비선형 계획법의 대화형 퍼지 의사결정

최규탁,남현우,박재민 慶南專門大學 1997 論文集 Vol.25 No.1

Pseudomonas aeruginosa 의 고온 충격 반응

최영길,최재연,채영규 漢陽大學校 環境科學硏究所 1991 環境科學論文集 Vol.12 No.-

최적의 성장 온도가 37℃인 Pseudomonas aeruginosa를 고온 충격(heat shock)을 주기 위하여 45℃와 48℃에서 각각 배양하였고, 이때 생성된 단백질들의 조성을 sodium dodecyl sulfate polyacrylamide gel electrophoresis(SDS-PAGE)를 이용하여 37℃에서 합성된 단백질들의 조성과 비교하였다. 실험을 수행한 45℃와 48℃에서 자란 균주가 37℃에서 자란 균주보다 적어도 3종류의 단백질(60kD, 68kD, 그리고 70kD)들을 더 많이 생성하였고 이들 단백질들은 고온에 의하여 생성된 잘못된 기능을 가진 단백질들을 세포내에서 제거하는 역할을 하고 있다. 같은 조건에 전사단계를 억제한 rifampicin 을 처리한 결과, 이들 단백질의 생성은 증가하지 않았다. 이상의 결과로 부터 45℃와 48℃에서 합성이 증가된 60kD, 68kD, 그리고 70kD의 단백질은 P. aeruginosa에서 고온 충격에 의해 전사단계에서 합성이 조절되는 고온 충격 단백질들임을 확인하였다. P. aeruginosa grows optimally at 37℃. When this strain has transferred to 45℃ or 48℃, the growth of the cell has been affected by the high temperature. Especially, some proteins(60kD, 68kD, and 70kD) were observed that those proteins were overexpressed to eliminate the malfunctional proteins, which were produced by high temperature in the cell. When the cell were grown at 45℃ or 48℃ with rifampicin, which is the transcription inhibitor, those effects were not observed. From these results, proteins produced from the culture conditions of 45℃ or 48℃ are clarified to be heat shock proteins which are regulated by the transcriptional level.

초등학생의 학부모-자녀 간의 의사소통유형과 문제행동과의 관계

김흥규 참마음교육학회 2006 未來敎育硏究 Vol.13 No.1

본 연구는 초등학생의 부모-자녀 간 의사소통유형과 문제행동과의 관계를 규명하여 초등학생의 문제행동을 미연에 방지하고 그들의 학교생활 적응을 도우며 나아가 학부모와 일선 교사들의 올바른 학생지도에 시사점을 주고자 한다. 이를 위해서 인천의 2개 초등학교에 재학하고 있는 4학년 120명과 5학년 80명, 그리고 6학년 84명 등 총284명을 대상으로 부모-자녀 간 개방적 의사소통과 역기능적 의사소통, 위축, 우울/불안, 신체증상을 포함하는 내재화 문제, 비행, 공격성을 포함하는 외현화 문제, 그리고 주의집중문제와 게임중독 경향성을 포함하는 문제행동 설문지로 양적 연구를 실시하였다. 연구결과 초등학생의 성별과 어머니의 취업유무, 주관적 행복감에 따라 문제행동의 하위 영역별로 의미 있는 차이가 나타났으며 부모-자녀 간의 개방적 의사소통 정도가 낮은 집단과 부모-자녀 간 역기능적 의사소통이 높은 집단에서 문제행동의 각 하위 변인별로 의미 있는 차이가 나타났다. 부모-자녀 간의 개방적 의사소통유형과 문제행동의 각 하위 변인들 간에는 부적 상관이, 부모-자녀 간의 역기능적 의사소통유형과 문제행동의 각 하위 변인들 간에는 정적상관이 있는 것으로 나타났다. This study was aimed at identifying if there are any interrelations among delinquent behaviors and types of communication between parents and elementary school children and also at determining if any background variables like gender of children and mothers' employment and subjective sense of happiness play a role in such relationship. The outcomes of the study showed that there was a high extent of interrelations among delinquent behaviors of youngsters and types of communication between parents and their children. Besides, the gender and mothers' employment and subjective view of happiness among background variables of youngsters were found to have significant impact on each sub-factor of their delinquent behaviors.

마이크로 콘트롤러를 사용한 극배치 PID 자기동조기의 구성

하재해,추연규,임영도,최부귀 동아대학교 공과대학 부설 한국자원개발연구소 1993 硏究報告 Vol.17 No.2

In this paper, a speed controller using one-chip microcontroller is implemented and applied to a DC Servo Motor. Adaptive control is applied to a system for which a priori knowledge to its mathematical model is insufficient, on the basis of input and output data an apropriate controller is constructed through which the system input is synthesized. The pole-placement PID self tuning control algorithms as a control algorithm is used to research the performance of the controller through experiments.