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The IceProd framework: Distributed data processing for the IceCube neutrino observatory
Aartsen, M.G.,Abbasi, R.,Ackermann, M.,Adams, J.,Aguilar, J.A.,Ahlers, M.,Altmann, D.,Arguelles, C.,Auffenberg, J.,Bai, X.,Baker, M.,Barwick, S.W.,Baum, V.,Bay, R.,Beatty, J.J.,Becker Tjus, J.,Becker, Elsevier 2015 Journal of parallel and distributed computing Vol.75 No.-
<P><B>Abstract</B></P> <P>IceCube is a one-gigaton instrument located at the geographic South Pole, designed to detect cosmic neutrinos, identify the particle nature of dark matter, and study high-energy neutrinos themselves. Simulation of the IceCube detector and processing of data require a significant amount of computational resources. This paper presents the first detailed description of IceProd, a lightweight distributed management system designed to meet these requirements. It is driven by a central database in order to manage mass production of simulations and analysis of data produced by the IceCube detector. IceProd runs as a separate layer on top of other middleware and can take advantage of a variety of computing resources, including grids and batch systems such as CREAM, HTCondor, and PBS. This is accomplished by a set of dedicated daemons that process job submission in a coordinated fashion through the use of middleware plugins that serve to abstract the details of job submission and job management from the framework.</P> <P><B>Highlights</B></P> <P> <UL> <LI> IceProd is a lightweight distributed workflow management framework. </LI> <LI> Uses existing middleware and protocols. </LI> <LI> Runs at user-level and is easily adaptable to other applications. </LI> <LI> It has been successful in managing 450k cores across 25 computing centers. </LI> <LI> Identified areas of improvement including scalability and load balancing. </LI> </UL> </P>
J. L. Ullmann,A. J. Couture,A. L. Keksis,D. J. Vieira,,J. M. ODonnell,J. M. Wouters,M. Jandel,R. C. Haight,R. S. Rundberg,T. A. Bredeweg,T. Kawano,C. Y. Wu,J. A. Becker,A. Chyzh,B. Baramsai,G. E. Mitc 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.23
A careful new measurement of the ^(238)U(n,γ) cross section from 10 eV to 100 keV has been made using the DANCE detector at LANSCE. DANCE is a 4π calorimetric scintillator array consisting of 160 BaF^2 crystals. Measurements were made on a 48 mg/cm^2 depleted uranium target. The cross sections are in general in good agreement with previous measurements. The gamma-ray emission spectra, as a function of gamma multiplicity, were also measured and compared to model calculations.
Garbes, L.,Kim, K.,Riesz, A.,Hoyer-Kuhn, H.,Beleggia, F.,Bevot, A.,Kim, M.,Huh, Y.,Kweon, H.S.,Savarirayan, R.,Amor, D.,Kakadia, Purvi M.,Lindig, T.,Kagan, K.,Becker, J.,Boyadjiev, Simeon A.,Wollnik, University of Chicago Press [etc.] 2015 American journal of human genetics Vol.96 No.3
As a result of a whole-exome sequencing study, we report three mutant alleles in SEC24D, a gene encoding a component of the COPII complex involved in protein export from the ER: the truncating mutation c.613C>T (p.Gln205<SUP>*</SUP>) and the missense mutations c.3044C>T (p.Ser1015Phe, located in a cargo-binding pocket) and c.2933A>C (p.Gln978Pro, located in the gelsolin-like domain). Three individuals from two families affected by a similar skeletal phenotype were each compound heterozygous for two of these mutant alleles, with c.3044C>T being embedded in a 14 Mb founder haplotype shared by all three. The affected individuals were a 7-year-old boy with a phenotype most closely resembling Cole-Carpenter syndrome and two fetuses initially suspected to have a severe type of osteogenesis imperfecta. All three displayed a severely disturbed ossification of the skull and multiple fractures with prenatal onset. The 7-year-old boy had short stature and craniofacial malformations including macrocephaly, midface hypoplasia, micrognathia, frontal bossing, and down-slanting palpebral fissures. Electron and immunofluorescence microscopy of skin fibroblasts of this individual revealed that ER export of procollagen was inefficient and that ER tubules were dilated, faithfully reproducing the cellular phenotype of individuals with cranio-lentico-sutural dysplasia (CLSD). CLSD is caused by SEC23A mutations and displays a largely overlapping craniofacial phenotype, but it is not characterized by generalized bone fragility and presented with cataracts in the original family described. The cellular and morphological phenotypes we report are in concordance with the phenotypes described for the Sec24d-deficient fish mutants vbi (medaka) and bulldog (zebrafish).
Searches for small-scale anisotropies from neutrino point sources with three years of IceCube data
Aartsen, M.G.,Ackermann, M.,Adams, J.,Aguilar, J.A.,Ahlers, M.,Ahrens, M.,Altmann, D.,Anderson, T.,Arguelles, C.,Arlen, T.C.,Auffenberg, J.,Bai, X.,Barwick, S.W.,Baum, V.,Beatty, J.J.,Becker Tjus, J. North-Holland 2015 Astroparticle physics Vol.66 No.-
<P><B>Abstract</B></P> <P>Recently, IceCube found evidence for a diffuse signal of astrophysical neutrinos in an energy range of ∼ 60 TeV to the PeV-scale [1]. The origin of those events, being a key to understanding the origin of cosmic rays, is still an unsolved question. So far, analyses have not succeeded to resolve the diffuse signal into point-like sources. Searches including a maximum-likelihood-ratio test, based on the reconstructed directions and energies of the detected down- and up-going neutrino candidates, were also performed on IceCube data leading to the exclusion of bright point sources. In this paper, we present two methods to search for faint neutrino point sources in three years of IceCube data, taken between 2008 and 2011. The first method is an autocorrelation test, applied separately to the northern and southern sky. The second method is a multipole analysis, which expands the measured data in the northern hemisphere into spherical harmonics and uses the resulting expansion coefficients to separate signal from background. With both methods, the results are consistent with the background expectation with a slightly more sparse spatial distribution, corresponding to an underfluctuation. Depending on the assumed number of sources, the resulting upper limit on the flux per source in the northern hemisphere for an <SUP> E - 2 </SUP> energy spectrum ranges from ∼ 1.5 · <SUP> 10 - 8 </SUP> GeV/cm<SUP>2</SUP> s<SUP>−1</SUP>, in the case of one assumed source, to ∼ 4 · <SUP> 10 - 10 </SUP> GeV/cm<SUP>2</SUP> s<SUP>−1</SUP>, in the case of 3500 assumed sources.</P> <P><B>Highlights</B></P> <P> <UL> <LI> We applied two methods to search for clusters of astrophysical neutrinos on background. </LI> <LI> Investigated both hemispheres separately and three different energy spectra. </LI> <LI> Saw underfluctuation consistent with background and set limits on astrophysical flux. </LI> <LI> Compared limits to recently found astrophysical flux to constrain number of sources. </LI> <LI> Excluded few sources of very hard energy spectra for seen astrophysical flux. </LI> </UL> </P>
DISCOVERY AND MASS MEASUREMENTS OF A COLD, 10 EARTH MASS PLANET AND ITS HOST STAR
Muraki, Y.,Han, C.,Bennett, D. P.,Suzuki, D.,Monard, L. A. G.,Street, R.,Jorgensen, U. G.,Kundurthy, P.,Skowron, J.,Becker, A. C.,Albrow, M. D.,Fouqué,, P.,Heyrovský,, D.,Barry, R. K.,Beau IOP Publishing 2011 The Astrophysical journal Vol.741 No.1
<P>We present the discovery and mass measurement of the cold, low-mass planet MOA-2009-BLG-266Lb, performed with the gravitational microlensing method. This planet has a mass of m(p) = 10.4 +/- 1.7 M-circle plus and orbits a star of mass M-star = 0.56 +/- 0.09 M-circle dot at a semimajor axis of a = 3.2(-0.5)(+1.9) AU and an orbital period of P = 7.6(-1.5)(+7.7) yrs. The planet and host star mass measurements are enabled by the measurement of the microlensing parallax effect, which is seen primarily in the light curve distortion due to the orbital motion of the Earth. But the analysis also demonstrates the capability to measure the microlensing parallax with the Deep Impact (or EPOXI) spacecraft in a heliocentric orbit. The planet mass and orbital distance are similar to predictions for the critical core mass needed to accrete a substantial gaseous envelope, and thus may indicate that this planet is a 'failed' gas giant. This and future microlensing detections will test planet formation theory predictions regarding the prevalence and masses of such planets.</P>
Westhovens, R,Robles, M,Ximenes, A C,Nayiager, S,Wollenhaupt, J,Durez, P,Gomez-Reino, J,Grassi, W,Haraoui, B,Shergy, W,Park, S-H,Genant, H,Peterfy, C,Becker, J-C,Covucci, A,Helfrick, R,Bathon, J BMJ Group 2009 Annals of the Rheumatic Diseases Vol.68 No.12
<P><B>Objectives:</B></P><P>To assess the efficacy and safety of abatacept in methotrexate-naive patients with early rheumatoid arthritis (RA) and poor prognostic factors.</P><P><B>Methods:</B></P><P>In this double-blind, phase IIIb study, patients with RA for 2 years or less were randomly assigned 1 : 1 to receive abatacept (∼10 mg/kg) plus methotrexate, or placebo plus methotrexate. Patients were methotrexate-naive and seropositive for rheumatoid factor (RF), anti-cyclic citrullinated protein (CCP) type 2 or both and had radiographic evidence of joint erosions. The co-primary endpoints were the proportion of patients achieving disease activity score in 28 joints (DAS28)-defined remission (C-reactive protein) and joint damage progression (Genant-modified Sharp total score; TS) at year 1. Safety was monitored throughout.</P><P><B>Results:</B></P><P>At baseline, patients had a mean DAS28 of 6.3, a mean TS of 7.1 and mean disease duration of 6.5 months; 96.5% and 89.0% of patients were RF or anti-CCP2 seropositive, respectively. At year 1, a significantly greater proportion of abatacept plus methotrexate-treated patients achieved remission (41.4% vs 23.3%; p<0.001) and there was significantly less radiographic progression (mean change in TS 0.63 vs 1.06; p = 0.040) versus methotrexate alone. Over 1 year, the frequency of adverse events (84.8% vs 83.4%), serious adverse events (7.8% vs 7.9%), serious infections (2.0% vs 2.0%), autoimmune disorders (2.3% vs 2.0%) and malignancies (0.4% vs 0%) was comparable for abatacept plus methotrexate versus methotrexate alone.</P><P><B>Conclusions:</B></P><P>In a methotrexate-naive population with early RA and poor prognostic factors, the combination of abatacept and methotrexate provided significantly better clinical and radiographic efficacy compared with methotrexate alone and had a comparable, favourable safety profile.</P>
Catalyst Studies for Ammonia Dissociation
( O. Becker ),( J. S. Lee ),( K. Lovegrove ),( A. Luzzi ) 한국화학공학회 2007 화학공학의이론과응용 Vol.10 No.1
Ammonia can be applied with solar thermal power plants as elegant closed-loop thermochemical energy storage system, facilitating continuous 24-hour solar power generation. The endothermic ammonia dissociation reaction of such a system has been successfully demonstrated using paraboloidal dish solar concentrators. The possibility of operating the system at lower temperatures substituting the conventional iron catalyst by ruthenium catalysts has recently been investigated. Lower operating temperatures would allow the use of more cost-effective parabolic trough collectors. To investigate the activity of a variety of potential iron as well as ruthenium catalysts in a systematic manner a microreactor arrangement has been established. The activity and properties of the different iron and ruthenium catalysts for the ammonia dissociation under high pressure will be compared and discussed.
Influence of wavelength-shifting films on multianode PMTs with UV-extended windows
Adamczewski-Musch, J.,Becker, K.-H.,Belogurov, S.,Boldyreva, N.,Chernogorov, A.,Deveaux, C.,Dobyrn, V.,Dü,rr, M.,Eom, J.,Eschke, J.,Hö,hne, C.,Kampert, K.-H.,Kleipa, V.,Kochenda, L.,Kolb, B.,K Elsevier 2015 Nuclear Instruments & Methods in Physics Research. Vol.783 No.-
<P><B>Abstract</B></P> <P>Wavelength-shifting (WLS) films were applied on UV-extended front windows of multianode photomultiplier tubes (MAPMTs) in order to increase the sensitivity of the MAPMTs at shorter wavelengths. The WLS material contained p-Terphenyl as photoactive component, which absorbs shorter wavelength photons ( < 300 nm ) and re-emits fluorescence photons around 350nm, i.e., at the maximum of the PMTs׳ sensitivity. The films were applied by means of dip-coating and the film performance was studied with respect to quantum efficiency, film homogeneity, and crosstalk on the MAPMTs. Using WLS-film-covered MAPMTs in a gaseous Ring Imaging Cherenkov detector, the number of detected photoelectrons per ring increased by up to 21% in an in-beam test.</P>
Observation of coherent elastic neutrino-nucleus scattering
Akimov, D.,Albert, J. B.,An, P.,Awe, C.,Barbeau, P. S.,Becker, B.,Belov, V.,Brown, A.,Bolozdynya, A.,Cabrera-Palmer, B.,Cervantes, M.,Collar, J. I.,Cooper, R. J.,Cooper, R. L.,Cuesta, C.,Dean, D. J.,D American Association for the Advancement of Scienc 2017 Science Vol.357 No.6356
<P>The coherent elastic scattering of neutrinos off nuclei has eluded detection for four decades, even though its predicted cross section is by far the largest of all low-energy neutrino couplings. This mode of interaction offers new opportunities to study neutrino properties and leads to a miniaturization of detector size, with potential technological applications. We observed this process at a 6.7s confidence level, using a low-background, 14.6-kilogram CsI[Na] scintillator exposed to the neutrino emissions from the Spallation Neutron Source at Oak Ridge National Laboratory. Characteristic signatures in energy and time, predicted by the standard model for this process, were observed in high signal-to-background conditions. Improved constraints on nonstandard neutrino interactions with quarks are derived from this initial data set.</P>
First constraint on coherent elastic neutrino-nucleus scattering in argon
Akimov, D.,Albert, J. B.,An, P.,Awe, C.,Barbeau, P. S.,Becker, B.,Belov, V.,Blackston, M. A.,Bolozdynya, A.,Cabrera-Palmer, B.,Cervantes, M.,Collar, J. I.,Cooper, R. L.,Daughhetee, J.,del Valle Coello American Physical Society 2019 Physical review. D Vol.100 No.11