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      • NSIP와 BOOP의 고해상전산화단층촬영 소견과 비교

        백상현,박재성,차장규,홍현숙,김대호,박성진,조준희,이혜경,최진수 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.2

        Purpose: BOOP and NSIP also share similar clinical features such as subacute flu-like illness, the finding of bronchoalveolar lavage, the result of pulmonary function test and more favourable outcome than usual interstitial pneumonia(UIP). The author try to compare the HRCT findings of NSIP with BOOP by pattern and distribution of diseases. Materials and Methods: HRCT findings of histopathologically proven NSIP(Group Ⅰ; 6, Group Ⅱ; 7, Group Ⅲ; 2) in 15 patients(5 male, 10 female, age range, 39-69 years; mean age, 53 years), BOOP in 15 patients(6 male, 9 female, age range, 26-76 years; mean age, 52 years) were reviewed retrospectively. Results: The common pattern of the two diseases was admixed consolidation, ground glass attenuation & reticular densities with/without architectural distortion(NSIP; 53.3%, BOOP; 46.7%). The main component of the pattern wan predominantly consolidation(NSIP; 46.7%, BOOP; 73.3%) and ground glass attenuation(NSIP; 40.0%, BOOP;20.0%). Architectural distotion was more provinent finding with NSIP(mild ; 3, moderate ; 4, severe; 2) compared with BOOP(mild; 7, moderate; 2, severe; 0). The predominant overall distribution was lower lung, peribronchovascular & peripheral lung field in both of the two entities(NSIP;73.3%, BOOP; 73.3%). Peribronchovascular involvement was more common with NSIP(100%) than BOOP(80%), whereas peripheral involvement was more common with BOOP(93.3%) than NSIP(80%). Conclusion: The HRCT findings of NSIP and BOOP were similar in pattern and distribution. But NIP manifested more frequently ground-glass attenuation, whereas BOOP showed more frequently consolidation. Architectural distortion was more severe with NSIP than BOOP. NSIP invoved more frequently peribronchovascular space and BOOP were more common in peripheral lung field.

      • 클라이밍 로봇을 활용한 고교각의 자동화 균열 평가

        배현진 ( Bae Hyun Jin ),장근영 ( Jang Keun Young ),안윤규 ( An Yun-kyu ) 한국구조물진단유지관리공학회 2019 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.23 No.1

        This paper proposes an automated crack evaluation technique for a high-rise bridge pier using a climbing robot. The proposed technique enables to automatically detect and quantify the bridge pier cracks even where cannot easily access by human for visual inspection. To achieve it, high quality images are obtained by scanning the vision cameras embedded on the climbing robot along the bridge pier surface. Then, a feature extraction-based image stitching algorithm is newly developed and applied for establishing the entire region of interest (ROI) images. The ROI images are then processed with a semantic segmentation algorithm for automated crack detection. Finally, the detected cracks are precisely quantified by a crack quantification algorithm. The proposed technique is validated using in-situ test data obtained from Jang-Duck bridge located at Gangneung city, South Korea. The test results reveal that the proposed technique successfully evaluate the bridge pier cracks with precision of 90.92 % and recall of 97.47 %.

      • KCI등재

        광주광역시 전문계 고등학교 특성화 및 종합발전방안

        나승일,정철영,김진모,안강현,한홍진,김기용,민상기,장현진 한국농업교육학회 2008 농업교육과 인적자원개발 Vol.40 No.1

        이 연구의 목적은 광주광역시 전문계 고등학교의 특성화 및 종합발전방안을 수립하는데 있다. 이 연구는 ① 전문계 고등학교 관련 선행연구 분석,② 인력육성 및 특성화 방향을 설정하기 위하여 광주광역시,전라남도,우리나라의 산업여건 분석,③ 광주광역시 전문계 고등학교에 대해 Malcolm Baldrige 평가모형에 의한 진단평가와 SWOT 및 활용전략 분석, ④ 광주광역시 전문계 고등학교의 개편 요구 분석,⑤ 광주광역시 전문계 고등학교의 특성화 및 종합발전방안 설정 등의 과정을 통해 수행되었다. 이 연구의 결과는 다음과 같다. 첫째,비전은 광주광역시 전문계고 특성화와 발전 역량 구축을 통한 산업체 요구에 부합하는 우수 인력 양성이며,이를 위한 전략은 특성화 체제구축,학교교육 혁신,인적 자원 혁신,학교경영 혁신,인프라 구축으로 설정하는 것이 필요하다. 둘째, 특성화 체제 구축은 특성화 체제 개편,교육과정 중심 특성화,학과 재배치 통합형 고교 도입,특성화고 신설을 통해 추진할 수 있 는데 특히,교육과정 중심 특성화가 적극 도입되어야 한다. 셋째,학교교육 혁신은 교육과정 개편,교수 학습 개선,진로지도 개선,시설 및 기자재 개선을 통해 추진할 수 있다. 넷째,인적자원 혁신은 학교 관리자 역량 강화,교원 역량 강화,학생 역량 강화를 통해 추진할 수 있다. 다섯째,학교경영 혁신은 경영 리더십 제고,경영 성과관리 강화,학교 재정 혁신을 통해 추진할 수 있다. 여섯째,인프라 구축을 위해 지자체,대학,산업체,지역주민과 연계 강화를 통해 추진할 수 있다. 일곱째,13개 전문계 고둥학교의 여건 및 특성에 적합한 단위학교별 특성화 및 종합발전방안을 수립하였다. The purpose of this study was to suggest strategies to specialize and develop vocational high schools in Gwangju Metropolitan City. The study was orderly performed as follows: (1) reviewing literature about vocational high school, (2) analyzing the condition of industries, (3) diagnosing the vocational high school through Malcolm Baldrige model, (4) analyzing the SWOT and application strategies, (5) analyzing the needs of reform, and (6) establishing the strategies for the specialization and development of Vocational High Schools in Gwangju Metropolitan City. The major findings of this study were as the following: First, the vision was to bring up excellent human resources to corresponds industrial needs through specialization and development of vocational high schools in Gwangju Metropolitan City. Five strategies to achieve it were creating the specialization system, innovating the school education, human resources, and the school management, and building the infrastructure. Second, creating the specialization system can be performed through five tasks which were restructuring the specialization system, creating curriculum-based specialization, trading departments in inter-schools, introducing an integrated high school, and building a new specialized high school. Especially curriculum based specialization needs to be accepted. Third, innovating the school education can be performed through four tasks which were reorganizing the curriculum, improving the teaching and learning, improving the career guidance, and improving the facilities and equipments. Fourth, innovating human resources can be performed through three tasks which were enhancing each competencies of a school manager, a teacher, and a student. Fifth, innovating the school management can be performed through three tasks which were improving the management leadership, developing the performance management, and innovating the school finance. Sixth, building the infrastructure can be performed through four tasks which were enhancing the relationships with a local government, colleges, industries, and local residents. Seventh, individual strategies for the specialization and development of thirteen vocational high schools were also developed by corresponding to their conditions and characteristics.

      • 태양광 발전 시스템 적용을 위한 관공서 전력 에너지 소비량 분석

        장민호,김현진,홍원화 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1

        The purpose of this study was to gather and categorize the data of electrical energy sources for public office buildings in Taegu, South Korea. The fossil energy sources are not enough for all of us, as we know, to use. In a few days, it will be hard to utilize or find them neither under the earth nor the sea or around the world. New energy sources should be recommended and solar energy has been referred to substitute these limited sources. Prior to studying solar energy sources applied to public office buildings, necessary data should be systematically surveyed and lined up. This research ,therefore, will be a very important foundation for studying next thesis, solar energy project.

      • 혐기성 소화시 온도와 기질 부하에 따른 메타생성균 거동에 관한 연구

        장현섭,황선진 경희대학교 2003 環境硏究 論文集 Vol.12 No.-

        Anaerobic digestion is a biological treatment process that has many advantages over the more conventional aerobic processes including low levels of excess sludge production, low space requirements and the production of valuable bigots. this study was carried out to evaluate the effect of organic loading rate on thermophilic(55℃) and mesophilic(35℃) anaerobic digestion. Moreover, fluorescent in situ hybridization(FISH) method was used for studying the microbial community it the reactors. The results of this study was as follows ; The stabilizing time of mesophiwic anaerobic reactors were shorter as approximately 20 days than 40 days of the thennrophiwic anaerobic reactors. The methane production of anaerobic reactors were independent of the feed substrate concentration and methanogens. The microbial diversity of two types of methanogenic reactor, mesophiwic (35℃) and thermophiwic (55℃), which had beet treating acetate-based artificial wastewater were compared. Methanogensis is carried out by microbial consortia consisting of bacteria and archer such as methanogens. the bacterial and archaic populations of all anaerobic reactors were investigated during a period of the process reflected by at accumulation of acetate. Archaea wore predominant it all reactors, and methanothrix-wike methanogens appeared it the mesophiwic anaerobic reactors with high feed substrate concentrations but it was tot preset it thermophiwic anaerobic reactors.

      • SBNR process에서 암모니아 부하가 N₂O 발생에 미치는 영향

        장광언,장현섭,황선진 경희대학교 2004 環境硏究 論文集 Vol.13 No.-

        A laboratory scale BNR reactor was built to study the fate of N₂O production during BBNR(Bhortcut Biological' Nitrogen Removal. process and A/O process. Nitrous oxide(N₂O) is emitted from wastewater treatment processes. It is known as a greenhouse gas that contributes to global warming. Therefore it is importance to develop technology, that can suppress N₂O emission. Especially, N₂O emission' from the SBNR process was higher than that of A/O process. When a ono loading was increased(0.15 ∼ 0.6g/㎥day), dissolved N₂O concentration of nitrification was increased. And when nitrite concentration of aerobic basin was increased(0 ∼200 mg/L). N₂O emission rate was increased. As a results of this study, BURN process had an more effect on N₂O emission than A/O process.

      • KCI등재

        주조용 CD4MCU 이상 스테인리스강의 Mo 첨가에 따른 인장 및 부식 거동

        장영환,손진일,김상식,이재현 대한금속재료학회 2005 대한금속·재료학회지 Vol.43 No.3

        In the present study, the effect of Mo contents on the microstructure, tensile and corrosion behaviors of as-solutionized CD4MCU cast duplex stainless steel was examined. The polarization test was conducted in 3.5% NaCl +5% H₂SO_(4) aqueous solution for general corrosion resistance and the slow strain rate tests were also conducted in air and 3.5% NaC1+5% H₂SO_(4) aqueous solution to study the stress corrosion cracking (SCC) of the present alloy. A substantial microstructural evolution of CD4MCU cast duplex stainless steel was observed with different Mo contents, which in turn affected the tensile and corrosion behaviors significantly. The beneficial effect of Mo on improving the corrosion and the SCC resistances was largely overwhelmed by this variation of microstructural characteristics. The relationship between the microstructural evolution and the tensile and corrosion behavior of CD4MCU cast duplex stainless steels with different Mo contents was discussed based on the optical and SEM micrographic and fractographic observations. (Received September 2, 2004)

      • 녹동균 세포외막 단백질 백신 CFC-1-101의 안정성 및 면역원성 검토 : 임상 제 Ⅰ/Ⅱa상 시험

        장인진,김익상,유경상,임동석,김형기,신상구,장우현,박완제,이나경,정상보,안동호,조양제,안보영,이윤하,김영지,남성우,김현수 대한감염학회 1998 감염 Vol.30 No.3

        목적 : 제일제당에서는 녹농균의 세포외막 단밸질을 유효성분으로 하는 백신인 CFC-101을 개발하였으며, 동물시험에서 이 백신의 안전성과 유효성을 입증하였다. 본 연구에서는 이 녹농균 백신의 인체에 대한 안전성과 면역원성을 평가하는 동시에 인체 접종시의 최적 투여 용량을 결정하기 위하여 제 I/Ⅱa상 임상시험을 수행하였다. 방법 : 건강한 성인 남자를 피험자로 선별하여 각 용량군에 백신투여자 6명, 위약투여자 2명을 배정하였다. 백신 투여군은 0.25mg, 0.5mg 또는 1.0mg 용량의 녹농균 백신을 7일 간격으로 3회에 걸쳐 근육주사 하였으며, 위약 투여군에게는 세포외막 단백질을 제외한 동일한 성분을 투여하였다. 백신접종 후 국소적 또는 전신적인 반응의 발생여부를 관찰하고, 혈액시료를 체취하여 백신의 역가와 유효성을 검정하였다. 결과 : 녹농균 백신 CFC-101은 모든 접종자에서 양호한 내약성을 보였다. 또한 0.5mg 과 1.0mg 백신 투여군에서는 100%의 항체양전율을 나타내었다. 생성된 항체는 녹농균 세포외막단백질에 특이성을 보였고, 녹농균 감염에 대해 방어효능이 있었다. 결론 : 이와같은 결과로부터 이 녹농균 백신은 인체에 안전하게 투여할 수 있으며, 높은 항체 생성능으로 감염방어 효능을 보이고 0.5mg과 1.0mg이 최적용량인 것으로 판단되었다. Background : We developed a Pseudomonas aeruginosa outer membrane protein(OMP) vaccine CFC-101, and the prophylactic efficacy of which has been demonstrated in animal models. In order to evaluate the safety and immunogenicity of the P. aeruginosa vaccine, we carried out a phase I/Ⅱa clinical trial in healthy male volunteers. Methods : Groups of eight volunteers, including two placebo subjects, were vaccinated intramuscularly with three doses of 0.25, 0.5 or 1.0 mg of the vaccine at one week intervals. Sings of systemic and local reactions observed after vaccination were recorded for each vaccinee for 5 days. Physical examinations were performed on days 0, 1, 7, 8, 14, 15, 21, and 42, and clinical laboratory tests were done on days 0, 3, and 21. Blood samples for assay of serum antibody levels were obtained up to 42 days after the first vaccination. Results : The vaccine was generally well tolerated by all vaccinees, showing no significant side effects. In the three dosage groups, all vaccinees, except one receiving the 0.25 mg dose, showed significant elevation in serum IgG antibody titers against the vaccine proteins, indicating 100% seroconversion in 0.5 and 1.0 mg groups. The human antibodies induced by the vaccine were specific for P. aeruginosa OMPs, as confirmed by western blot analysis and immunoprecipitation assays. The capacity of the human antisera to enhance opsonophagocytic killing activity by polymorphonuclear leukocytes and to confer protection against P. aeruginosa infections indicates that the antibodies elicited by the vaccine have protective efficacy. Conclusion : We conclude that the P. aeruginosa OMP vaccine is safe and effective for human use and its optimal dose to be 0.5 or 1.0 mg.

      • 가공 및 측정이 가능한 복합나노가공시스템의 개발

        장동영,박만진,김진현,한동철 한국공작기계학회 2004 한국공작기계학회 춘계학술대회논문집 Vol.2004 No.-

        In focused-ion-beam (FIB) application of micromachining and device transplantation, four kinds of FIB processes, namely FIB sputtering, FIB-induced etching, redeposition, and FIB-induced deposition, are well utilized. As with FIB systems, scanning electron microscopes(SEMs) were extensively used in the semiconductor industry. They are the tools of choice for defect review and providing the image resolution needed for process monitoring. The enhanced capabilities of a dual-column on one chamber system are quickly becoming realized by the nano industry for performing a wide range of application.

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