가토 외고정 모델을 이용한 치밀체형 세라믹스의 골결합능 평가

이재협,이동호,이재학,공현식,안영준,류현승,서준혁,홍국선,김환,장봉순,이춘기 대한정형외과연구학회 2003 대한정형외과연구학회지 Vol.6 No.2

동일한 환자에서 조혈모세포이식 전후의 호중구감소 기간 중 감염양상에 대한 비교연구 : 중심정맥관 관련 패혈증을 중심으로 Based on Central Venous Catheter Related Septicemia

류재호,노규태,이영석,이영호,권혁찬,김재석,김효진,이영민,박혜원,박근희 대한조혈모세포이식학회 2002 대한조혈모세포이식학회지 Vol.7 No.1

연구배경: 동일한 환자를 대상으로 조혈모세포이식 전 일반 병실에서의 관해유도 항암제치료 및 강화요법으로 인한 호중구감소 기간의 감염양상과 고용량 항암제치료 후 무균실에서의 조혈모세포이식 시 호중구감소 기간의 감염양상을 중심정맥관 관련 패혈증을 중심으로 비교 연구함으로써 효율적인 감염관리지침을 마련하고자 하였다. 대상 및 방법: 1999년 1월부터 2001년 7월까지 2년 7개월간 동아대학교병원 일반병실에서 악성혈액질환으로 항암제 치료를 받다가 조혈모세포이식을 시행받았던 22명을 대상으로 중심정맥관 관련 패혈증의 형태를 비교분석하였다. 결과: 대상 환자들의 일반병실과 무균실에서의 입원기간은 각각 32±13일, 33±19일, 호중구 감소기간은 15±12일, 17±18일, 호중구 감소기간의 발열 횟수는 14회, 14회로서 입원병실의 종류에 따른 차이는 없었다. 환자들의 중심정맥관 사용일수는 일반병실에서 29일(7~545일), 무균실에서 100.5일(25~606일)이었으며, 총 사용일수는 각각 1,515일, 3,250일로서 무균실에서의 중심정맥관 사용일수가 의미 있게 길었다(P=0.001). 중심정맥관 사용 일수에 대한 감염률은 각각 5.28/1,000일, 3.08/1,000일로서 일반병실에서 그 빈도가 높았으나 통계적 유의성은 보이지 않았다(P=0.141). 결론: 중심정맥관 삽입 후 일반병실에서 항암제 치료를 받던 환자가 조혈모세포이식을 위하여 무균실에 입원하는 경우, 중심정맥관을 교체하는 것이 감염관리를 위하여 바람직할 것으로 생각된다. Background: We compared the incidence of central venous catheter (CVC) related septicemia during neutropenic period in the same patient, which developed following chemotherapy for remission induction and consolidation, or hematopoietic stem cell transplantation (HSCT). Methods: We retrospectively reviewed the medical records and laboratory data of 22 patients with hematologic malignancies who received anticancer chemotherapy followed by HSCT at Dong-A University Hospital between January, 1999 and July, 2001. We investigated the duration of hospitalization, duration of neutropenic period, duration of catheterization, microbiologically documented organisms and incidence of CVC related septicemia. Results: The data in general ward (before HSCT) and laminar air flow room (after HSCT) were as follows: duration of hospitalization was 32±13 days and 33±19 days, duration of neutropenic period was 15±12 days and 17±18 days, median duration of catheterization was 29 days (7~545 days) and 100.5 days (25~606 days) (P=0.001), and incidence of CVC related septicemia was 5.28/1000 days and 3.08/1000 days, respectively. In the CVC related septicemia, the most common etiologic organism was coagulase negative staphylococcus. Conclusion: We suggest that the exchange of CVC before admission to laminar air flow room could decrease the incidence of CVC related septicemia in HSCT recipients.

건강한 성인에서 발병한 칸디다와 연관된 위궤양 1례

박지훈,이상혁,김희,이재호,박성재,지삼룡,양성연,박은택,이연재,설상영,정정명,강미선 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Fungus such as Candida albicans is a normal flora that is frequently found in the oral cavity, gastrointestinal tract, genitourinary tract, vaginal mucosa in a normal person. However, candida can cause opportunistic infection in an immune compromised host. Candidiasis has broad spectrum of disease from mucocutaneous infection to invasive or disseminated infection. But, it is rarely reported that candida is associaed with gastrointestinal tract disease in a healthy adult. The case of gastric ulcer associated with candida particularly in a health adult is reported with relevant literature.

바터 팽대부에 생긴 유암종 1예

강명주,지삼룡,박석주,이재익,조영완,김준영,박성재,박은택,이연재,이상혁,설상영,배상균 인제대학교 2006 仁濟醫學 Vol.27 No.-

Carcinoid tumors have been reported in a wide range of organs but most commonly involve the lungs, bronchi and gastrointestinal tract. Within the gastrointestinal tract, appendix is the most common location for carcinoid, followed by the distal small intestine, the rectum, and the stomach. Among these, primary involvement of the ampulla of Vater is extremely rare. We report a case of carcinoid tumor of ampulla of Vater. A 62-year-old man presented with epigastric soreness. Gastroduodenal endoscopy showed hyperemic bulging mass on ampulla of Vater and diagnosed as carcinoid tumor by histologic finding, with immunohistochemical study. In ^(111)In-octreoscan, tumor had regional lymph node metastasis, but no evidence of distant metastasis. Pancreatoduodenectomy with lymph node dissection was performed.

간세포암의 고주파 열치료 후 천자침 경로를 통한 전이 1례

조영완,박석주,진한영,김준영,이재익,강명주,박정하,윤정희,박성재,지삼룡,이연재,이상혁,설상영 인제대학교 2006 仁濟醫學 Vol.27 No.-

Radiofrequency ablation(RFA), as a form of minimally invasive therapy for hepatocellular carcinoma, has become an important treatment modality. Because of limitation of surgery, RFA has become standard therapy for hepatocellular carcinoma in some situations. But there are some complications of RFA such as bleeding, infection, hematoma, adjacent organ thermal damage including intestinal perforation, needle track seeding, and so on. There are few reports in the literature that systematically evaluate the incidence of needle tract seeding and its associated risk factors. And only 2 cases of needle tract seeding of hepatocellular carcinoma after RFA were reported in Korea. We report a case of needle tract seeding of hepatocellular carcinoma after RFA.

Coevaporation에 의한 cd₁-xZn_(x)S 박막 제작 및 특성에 관한 연구

李載亨,李虎烈,朴鏞冠,申成浩,申載爀,朴光子 성균관대학교 1998 학술회의지원논문목록집 Vol.1998 No.-

In this paper, structural optical and electrical properties of Cd_(1-x)Zn_(x)S thin films prepared by coevaporation method were studied. Also, effects of ZnS mole ratio(x) to CdS on properties of thin film Cd_(1-x)Zn_(x)S/CdTe solar cells were investigated. When the ZnS mole ratio was less than 0.85, the crystal structure of Cd_(1-x)Zn_(x)S films was hexagonal with the c axis aligned perpendicular to the substrate. For x>0.85, however, the Cd_(1-x)Zn_(x)S films were grown with cubic zincblende structire. As the ZnS mole ratio increased the lattice constant of Cd_(1-x)Zn_(x)S films rapidly increased with ZnS mole ratio. The open circuit voltage of Cd₁xZnxS/CdTe solar cells increased with x due to reducing of the electron affinity difference between Cd₁xZnxS and CdTe films. However, the increase of series resistance due to the high resistivity of Cd_(1-x)Zn_(x)S films results on reducing conversion efficiency.

다가야스병에 의한 돌연사 부검 1예

이재혁,조승제,박종태 大韓法醫學會 1994 대한법의학회지 Vol.18 No.1

A 22-year old male patient was admitted to the Emergency room of local clinic because of the stuporous mental status. On physical examination, he appeared as a chronically ill, slender man. There was complete absence of the left arm pulse, and a prominent thrill and briuts were present over the right subclavicular area. The blood pressure which checked in the other regions except for the left arm was hypertensive(right arm 180/100, right leg 210/120, and left leg 200/130mmHg). An x-ray film of the chest and doppler ultrasounds showed characteristic dilatation of aortic arch, ascending aorta and innominate artery. The clinical impression was Takayasu's disease. This patients's condition deteriorated rapidly in spite of intensive care and died on the seventh hospital day. At autopsy, the cause of death was massive left brain infarction due to middle cerebral artery embolization. The opened luminal surface of the aorta and its major branches revealed irregulary thick-walled, tree-bark-like appearance. Also in the left common carotid artery, the lumen was nearly obliterated by thromi and intimal fibrous plaques. But the thoraco-abdominal aorta was spared. Microscopic examination disclosed granulomatous and sclerosing arteritis. In the former, the inflammatory process was confined to the media and adventitia and the cell infiltrate consisted predominantly of lymphocytes, plasma cells and histiocytes, with a varying number of giant cells. The latter was characterized bland intimal fibrous hyperplasia, medial degeneration with disrupted elastic lamella, and adventitial fibrosis. The pathologic diagnosis was Takayasu's disease of type I.

N-tert-Butyl-2-(1-acetoxy-2-fluoro-1-butyl) benzenesulfonamide 의 결정 및 분자구조

이재혁,김문집,김대황 순천향대학교 기초과학연구소 1997 순천향자연과학연구 논문집 Vol.3 No.1

The crystal structure of N-tert-Butyl-2-(1-acetoxy-2-fluoro-1-butyl) benzenesulfonamide has been determined from single crystal X-ray diffraction study ; C16H24FNO4S, Orthorhombic, Pbca, a=14.652(5)Å, b=18.477(2)Å, c=13.261(2)Å, α=β=γ=90°, V=3590.1(14)ų, T=296(2)K, Z=8, Mok α(λ=0.71069Å). The molecular structure was solved by direct method and refined by full-matrix least squares to a final R=5.55% for 1628 unique observed F0>4σ(F0) reflections and 208 parameters. The conformation of the molecule is stabilized by an intramolecular N(19)-H(19)...O(10) hydrogen bond.

Ammonium Hydrogen D-Tartrate의 결정 및 분자구조

이재혁,이한준,김문집 순천향대학교 기초과학연구소 1998 순천향자연과학연구 논문집 Vol.4 No.2

The structure of Ammonium Hydrogen ?? has been determined by X-ray diffraction methods. The crystals are Orthorhombic, space group P2₁2₁2₁, unit cell constants, a=7.848(1)Å, b=11.070(1)Å, c=7.651(2)Å, α=β=γ=90°, V=664.7(2)ų, T=293(2)K, Z=4, ??. The intensity data were collected on an Enarf-Noius CAD-4 Diffractometer with graphite monochromated Cu Ka radiation. The molecular structure was solved by direct method and refined by full-matrix least squares to a final R=6.46% for 759 unique observed ?? reflections and 138 parameters. The molecular have 7 intermolecular hydrogen bonds.

진균성 부비동염의 임상적 양상과 내시경수술의 치료 결과

이봉재,김혁,김재호,김용재 대한이비인후과학회 1998 대한이비인후과학회지 두경부외과학 Vol.41 No.3