붕장어 부산물로 제조한 붕장어탕의 식품학적 특성

허민수(Min Soo Heu),이택상(Take Sang Lee),김혜숙(Hye-Suk Kim),지성준(Seung Joon Jee),이재형(Jae Hyoung Lee),김형준(Hyung Jun Kim),윤민석(Min Seok Yoon),박신호(Shin Ho Park),김진수(Jin-Soo Kim) 한국식품영양과학회 2008 한국식품영양과학회지 Vol.37 No.4

붕장어 가공부산물인 머리와 frame를 효율적으로 이용하기 위한 일련의 연구로 붕장어 부산물을 이용한 붕장어탕의 개발을 시도하였고, 아울러 이의 식품성분 특성에 대하여도 살펴보았다. 살균조건 및 가온일수에 따른 붕장어탕의 저장성 부여를 위한 최적 살균조건은 F? value=8분으로 판단되었다. 붕장어탕의 일반성분은 수분의 경우 90.7%, 조단백질의 경우 4.8%, 조지방의 경우 2.6%, 조회분의 경우 1.5%를 나타내었다. 붕장어탕의 엑스분 질소 함량은 243.1 ㎎/100 g으로 시판 추어탕의 208.0 ㎎/100 g보다 높았다. 붕장어탕의 총 아미노산 함량은 4,310 ㎎/100 g이었고, 주요 구성아미노산은 glutamic acid(637.3 ㎎/100 g, 14.8%), glycine(409.1 ㎎/100 g, 9.5%) 및 alanine(404.4 ㎎/100 g, 9.3%)등이었다. 붕장어탕은 관능적인 비린내는 거의 감지되지 않았고, 맛은 우수하였으며, 항산화능이 인정되었으나 ACE 저해능은 크게 기대할 수 없었다. For the effective use of the conger eel by-products, such as head and frame, Tang, which is the Korean-type soup, from conger eel by-products (TCEB) was developed and its food component characterization was compared with that of commercial Chueotang, loach Tang. According to the results of viable cells and coliform group of TCEB heated at 115oC for various times, the reasonable F0 value was 8 min. The proximate composition of TCEB was 90.7% for the moisture, 4.8% for the protein, 2.6% for the lipid, and 1.5% for the ash. The extractive-nitrogen content of TCEB was 243.1 ㎎/100 g, which was higher than that of commercial Chueotang, 208.0 ㎎/100 g. The total amino acid content of TCEB was 4,310 ㎎/100 g and its major amino acids were glutamic acid (637.3 ㎎/100 g, 14.8%), glycine (409.1 ㎎/100 g, 9.5%) and alanine (404.4 ㎎/100 g, 9.3%). TCEB was not felt in the sensual fish odor and its sensual taste was good. The health functional properties for health of TCEB were 1.29 as a PF (protection factor) for antioxidative activity and 39.4% for angiotensin Ⅰ converting enzyme (ACE) inhibiting activity.

Forced suction thrombectomy in patients with acute ischemic stroke using the SOFIA Plus device

Roh Hyun Ki,Ju Min-Wook,Byoun Hyoung Soo,Park Bumsoo,Park Kwang Hyon,Jeongwook Lim 대한뇌혈관외과학회 2022 Journal of Cerebrovascular and Endovascular Neuros Vol.24 No.3

Objective: Stent retrieval thrombectomy has recently been the standard treatment for acute ischemic stroke with large artery occlusion. However, the development of catheters for suction thrombectomy has recently led to results comparable to that of stent retrieval thrombectomy (SRT). This study aimed to analyze the safety and efficacy of forced suction thrombectomy (FST) using the SOFIA Plus (MicroVention Terumo, Tustin, CA, USA) device.Methods: We included patients with acute ischemic stroke who underwent FST using the SOFIA Plus device at our institution. Medical records and angiographic data were reviewed, and the results of this study were compared with those of other FST studies.Results: A total of 35 patients were included in this study. The occlusion sites were the internal carotid artery terminal (4), M1 segment (20), and posterior circulation (11). Of the 35 patients, FST was performed in only 21 (60%) patients, and the remaining 14 (40%) patients underwent SRT and FST. In all cases, the recanalization rate was 100%, and the average time from groin puncture to recanalization was 21±4.94 min. In particular, the average time required to reach the SOFIA Plus lesions from the groin puncture was 10.44±5.06 min and about 67% of the FST patients were recanalized at the first attempt. Three-months modified Rankin Scale (mRS) score of ≤2 was observed in 52% of the patients.Conclusions: Forced suction thrombectomy using the SOFIA Plus yielded a high recanalization rate within a shorter time. In particular, the recanalization rate was higher than that reported in previous studies using other types of suction devices.

A chemically regenerative redox fuel cell using (2,2,6,6-tetramethylpiperidin-1-yl)oxyl redox reaction in acid medium

Han, Sang-Beom,Kwak, Da-Hee,Park, Hyun Suk,Park, Jin-Young,Ma, Kyeng-Bae,Won, Ji-Eun,Kim, Do-Hyoung,Kim, Min-Cheol,Park, Kyung-Won Elsevier 2018 Journal of Power Sources Vol.393 No.-

<P><B>Abstract</B></P> <P>(2,2,6,6-tetramethylpiperidin-1-yl)oxyl (TEMPO) with no free radical and non-volatile characteristic can be utilized as a liquid catalyst instead of O<SUB>2</SUB> at the cathode in a chemical regenerative redox fuel cell with H<SUB>2</SUB> as a fuel at the anode. In this study, the electrochemical properties and performance of TEMPO dissolved in sulfuric acid solution are investigated using half and unit cells. In the half-cell, TEMPO shows an activation energy of 1.27 kcal mol<SUP>−1</SUP> K<SUP>−1</SUP> for the reduction. A chemical regenerative redox fuel cell (CRRFC) using TEMPO as the liquid catalyst exhibits an open circuit voltage of 0.7 V and a maximum power density of 90 mW cm<SUP>−2</SUP> at 30 °C with a low activation loss. The regeneration cycling test of the CRRFC is performed at a constant voltage of 0.4 V under a flow rate of the oxygen-bubbled TEMPO solution. The performance of the CRRFC deteriorates, i.e., a power density of zero measured at >200 min. Thus, a highly efficient regeneration system needs to be developed for a high-performance CRRFC using TEMPO used as a liquid-type oxidant. Furthermore, stable liquid oxidants with relatively high standard reduction potentials can be proposed through various organic compounds.</P> <P><B>Highlights</B></P> <P> <UL> <LI> CRRFC was proposed using TEMPO instead of O<SUB>2</SUB> at the cathode. </LI> <LI> TEMPO showed fairly fast transport and low activation energy for the reduction. </LI> <LI> CRRFC exhibited an open circuit voltage of ∼0.7 V at 30 °C. </LI> <LI> CRRFC exhibited a maximum power density of ∼90 mW cm<SUP>−2</SUP> at 30 °C. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

요추간판 탈출증 환자에서 수술후 운동요법이 기능적 회복에 미치는 영향에 관한 연구

민경수,박형천,김현주 충북대학교 의과대학 충북대학교 의학연구소 1996 忠北醫大學術誌 Vol.6 No.1

요추간판 탈출증은 기능적 척추단위의 퇴행성 변화에 의한 질환들의 일부분이며 성공적으로 수핵을 제거하고 신경근을 감압하였다 하더라고 그 기본적인 병태생리적 과정을 차단하는 것은 아니다. 또한 수술적 치료가 일반화되고 높은 성공율이 보고되고 있음에도 불구하고 상당수에서 요통, 신체적 수행능력의 장애, 정신심리적 장애가 있어 정상적인 생활로의 복귀에 문제가 있으며 추간판 탈출증 수술후 환자들에게서 수술후 척추의 가동성이나 유연성, 복근, 척추배근 등의 근력을 측정한 결과 정상인과 현격한 차이가 있는 것으로 보고되고 있다. 따라서 추간판 탈출증 수술후 환자들에게도 운동요법을 중심으로한 재활치료가 필요하며 그 효과를 평가하기 위하여 25명의 추간판 탈출증 수술후 환자들을 대상으로 운동요법을 교육시켜 실시한 12명의 실험군과 그렇지 않은 13명의 대조군으로 나누어 퇴원 1달후까지 추적관찰을 통하여 그 결과를 비교 분석하였다. 운동요법은 수술 2일 후부터 하지의 관절가동역 및 유연성의 증대, 근력강화를 위한 3가지 운동을 실시하였으며 수술 1주 후부터는 체간의 굴곡운동, 신장운동 4종류를 추가하였다. 결과의 평가 척도로는 수술후 입원일수, 요통 및 하지 방사통의 통증점수, 활동능력의 장애도 등을 이용하였다. 그 결과 실험군의 환자들은 운동요법에 대해 매우 긍정적인 반응을 보였으며 순응도가 높았다. 그러나 수술후 입원기간, 퇴원 1달후 요통의 정도, 수술 1주후에서 퇴원 1달후까지 요통의 호전정도, 퇴원 1달후 활동능력의 장애도는 양군에서 통계적으로 유의한 차이가 없었다. 반면 수술 1주후에서 퇴원 1달후까지 하지 방사통의 호전정도는 실험군에 유의하게 좋은 것으로 나타났다. 그러나 이러한 결과만 가지고 운동요법의 효과를 판단하기에는 부족한 점이 많으며 앞으로 표본의 수를 늘리고 더 장기간 추적 관찰을 하는 것이 필요하며 구체적 운동방법의 선택적용에 있어서도 그 효과를 최적화하기 위한 연구들이 필요하다. Herniation of the lumbar disc is a portion of the spectrum of degenerative diseases of the functional spinal unit and, successful decompression of the nerve root by discectomy can not prevent the progression of the degenerative process. Despite of high success rate of surgery there are many patients who can not return to mormal life and work due to postoperative pain, physical impairment, and psychologic distress. And there are resports on postdiscetomy patients having significantly decreased mobility of the spine, strength and endurance of abdominal muscles and trunk extensors. So a rehabilitation program focused on exercise therapy is necessary in postdiscectomy patients. To evaluate the effects of the exercise therapy 25 postdiscectomy patients consisted of 12 patients educated on postoperative exercise and 13 patients of control group were followed-up for 1 month after discharge. In case group exercise therapy was started on the second postoperative day with 3 kinds of lower extremity exercises for the improvement of mobility and strength. And 4 kinds of flexion and stretching exercises of the trunk were added 1 week postoperatively. As scales of evaluation the duration of the postoperative admission, pain scores and duration of low back pain and radiating leg pain, and disability of nine basic activities of daily living were used. As results the patients in the case group showed very affirmative reponse to the exercise therapy and were very compliant. But the duration of postoperative admission, pain scores in low back pain at follow-up 1 month, the degree of improvement in low back pain scores from postoperative 1 week to follow-up 1 month showed no statistically significant difference between two groups. The disability index at follow-up 1 month also showed no statistically significant difference. On the contrary, the degree of improvement in leg pain scores from postoperative 1 week to follow-up 1 month showed significant difference(p=0.0048) between two groups. But these results are insufficient for the evaluation of the effectiveness of exercise therapy and further studies with more cases with long-term follow-up to optimize the exercise therapy program are necessary.

'퇴원설명문'에 의한 72시간내 부적절한 응급센터 재방문의 감소

박하영,심민섭,송형곤,송근정 한국의료QA학회 2005 한국의료질향상학회지 Vol.12 No.1

Background : Patients who were discharged from the emergency department(ED) may revisit. These patients are divided into two groups; one is expected scheduled condition, the other is unexpected condition. These patients of inappropriate revisits to the ED would be unsatisfied, difficult to make rapport and take legal action as a result of additional medical charges. The purpose of this study was to reduce inappropriate revisits to the ED with a new method which was developed by analyzing inappropriate revisits in 2002. Methods : This study was conducted in a tertiary hospital consisting of 1,278 beds. The most common cause of inappropriate revisits was the medical team's lack of explanation about a disease. Thus we decided that the effective method was to offer full explanations to patients to understand the clinical pathway of a disease. We made four types of stickers to explain most common 4 diseases in 2003. An emergency physician completed 'discharge explanation report' and explained it to patients in 2004. Results : In 2002 inappropriate revisited patients were 164, patients with four diseases were 79. During the same period of 2003, inappropriate revisited patients were 56 (-65.9%), four disease patients were 6 (-92.4%) and in 2004 inappropriate revisited patients were 52, four disease patients were 19. Causes of revisits were lack of explanation about a disease in 35 patients (44.3%) in 2003, and 5 patients (83.3%) in 2003, and 16 patients (84.2%). Conclusions : Application of 'explanation stickers' at discharge reduced inappropriate revisits from 34.5% in 2002 to 15.9% in 2003. Application of 'Discharge explanation report' by emergency physician reduced inappropriate revisits from 15.9% in 2003 to 13.5% in 2004. Reduction of inappropriate revisits elevated the quality of medical treatment, and decreased patients' dissatisfaction in ED.

산업폐기물인 폐주물사를 혼입한 콘크리트의 최적배합설계

박재선,김태경,백민경,이주형,윤경구,김남윤 강원대학교 석재복합신소재제품연구센터 1997 석재연 논문집 Vol.2 No.-

산업폐기물인 폐주물사를 재활용하여 에너지 절감과 환경오염효과를 얻을 수 있다. 반요인실험법을 사용하여 폐주물사를 잔골재에 일정비율 치환한 콘크리트의 최적배합설계 제시를 위한 예비실험에서 물-시멘트비, 폐주물사의 잔골재 치환율, 잔골재율, 슬럼프와 같은 주요변수와 변수사이의 2차상호작용을 파악하였다. 예비실험결과 폐주물사의 잔골재치환율을 70%까지 실시하였을 때 폐주물사를 혼입한 콘크리트의 강도발현에 가장 중요한 변수는 물-시멘트비로 분석되었고 폐주물사의 잔골재치환율은 거의 영향이 없는 것으로 분석되어 폐주물사를 콘크리트의 잔골재로 대체할 수 있음을 알 수 있었다. 각 변수의 2차상호작용에서는 폐주물사의 잔골재 치환율과 잔골재율의 상관관계가 콘크리트의 강도발현에 가장 큰 영향을 미치는 것으로 나타났다. 목표압축강도에 대한 최적배합조건을 폐주물사의 잔골재 치환율에 따라 물-시멘트비, 잔골재율에 대해 제시하였다. The waste foundry sand might be recycled in concrete, saving energy and protect-ing environment. An half- factorial experiments were performed with the primarary variable such as water- cement raito, waste foundry sand substitution ratio, fine agg-regate ratio and slump as a preliminary study for optimum mix design of concrete. The preliminary study show that the water- cement ratio is the most important factor to the concrete strength, followed by slump. The substitute of waste foundry sand up to 70% has little infulence, indicating that it can substitute the fine aggregate without damaging the Concrete strength. The interaction between waste foundry sand substitution ratio and fine aggregate ratio was most significant to the concrete strength among the 2-way interaction variable. Only compressive strength affect to the formation of optimum mix design area as target compressive strengh becomes bigger. Optimum mix designs of concrete incorporating waste foundry sand, satisfying the target responses, were proposed in terms of waste foundry sand substitution ratio, water cement ratio and fine aggregate ratio.

배자기 중 인간 사지의 형태발생에 관한 연구

박형우,민양기,심용운 대한해부학회 1992 Anatomy & Cell Biology Vol.25 No.1

다제내성 그람양성균에 대한 Linezolid(Zyvox^(�))의 시험관내 항균력 비교

박대원,정희진,엄중식,황병연,김성범,이재갑,이연주,정혜원,정성주,박재형,이진수,손장욱,김우주,김민자,박승철 대한감염학회 2003 감염과 화학요법 Vol.35 No.5

배경 : MRSA, VRE, VRSA같은 다제 내성 그람 양성균의 등장에 따라 glycopeptide를 대체할 새로운 항생제의 개발이 필요하게 되었고 결과적으로 새로운 항생제인 linezolid라는 항생제가 개발되었다. Linezolid는 이전의 항생제와는 다른 새로운 계열의 oxazolidinone으로 경구 이용률이 우수하다. 원내 및 원외감염의 중요한 원인균이 되고 있는 MRSA, VRE에 대한 적절한 경구용 항균제가 없는 국내에서 폐렴 및 피부 연조직 감염에서 경구용으로 사용해 볼 수 있는 약제이다. 본 연구에서는 고대 구로 병원에서 분리된 MRSA, VRE 등을 대상으로 다른 여러 항균제와 비교한 linezolid의 시험관내 항균력을 조사하고자 하였다. 재료 및 방법 : 연구대상은 1998년 1월부터 2000년 12월까지 본원에서 입원 및 외래를 통하여 피부 연조직 감염증 및 호흡기 감염증, 요로감염증으로 진단된 환자들의 가검물로부터 분리된 MRSA 60균주, VRE 43균주, PRSP 25균주를 액체배지 또는 한천배지 희석법을 통하여 linezolid 및 기타 항균제에 대한 최소발육억제농도를 구하였다. 결과 : 실험에 사용한 S. aureus는 모두 MRSA였고 이들은 linezolid에 대해 MIC_(90) 2㎍/㎖(MIC 범위 1-2㎍/㎖), Enterococcus spp는 모두 VRE로 linezolid의 MIC_(90)은 2㎍/㎖로 MIC 범위는 1-4㎍/㎖였다. 한 개의 균주에서 MIC 4㎍/㎖로 중등도 감수성을 보였으나 MIC breakpoint가 (8㎍/㎖인 내성균주는 없고 모두 감수성을 보였다. S. pneumoniae의 경우 penicillin 내성이었고, linezolid MIC_(90) 1㎍/㎖ (MIC 범위 0.5-1㎍/㎖)로 전부 감수성을 보였다. 결론 : Linezolid는 MRSA를 위시한 VRE, PRSP 등의 다제 내성 그람 양성균에 대하여 우수한 시험관내 항균력을 보임을 알 수 있었다. Background : The emergence of multi-drug resistant Gram-positive cocci, such as MRSA, VRE, and VRSA, necessitated to develop new antibiotics, which could replace the glycopeptide. As a result, a new antibiotics named linezolid was developed. Linezolid is different line of oxazolidinones with a good oral bioavailability, compared to other antibiotics. Since appropriate oral antibiotics are not presently available for MRSA, which is a major cause of nosocomial and community acquired infections, the introduction of linezolid will have favorable effect on treatment of infections such as pneumonia or skin infections. In this study, we investigated the antibiotic effect of linezolid on MRSA and VRE isolated from patients who were treated in Korea University Guro Hospital. Material and Methods : By using broth microdilution and agar dilution method we measured minimum inhibitory concentration (MIC) with sixty S. aureus, forty three Enterococcus spp., and twenty five S. pneumoniae isolates from patients who were diagnosed as skin, soft tissue, respiratory, and urinary infections in Korea University Guro Hospital from January, 1998 to December, 2002. Results : All of S. aureus used in this study were MRSA, and MIG_(90) of linezolid was below 2 ㎍/㎖ (MIC ranged between 1-2 ㎍/㎖). All of Enterococcus spp. were VRE, and had MIG_(90) of 2 ㎍/㎖ (MIC ranged between 1 to 4 ㎍/㎖). One of the VRE showed intermediate susceptibility with MIC of 4 ㎍/㎖. However, none was resistant with MIC breakpoint above 8 ㎍/㎖. All of S. pneumoniae were resistant to penicillin, but they were susceptible to linezolid with MICao of 1 ㎍/㎖(MIC range 0.5-1㎍/㎖). Conclusion : In conclusions, linezolid has an excellent in vitro antibiotic effect on multi-drug resistant Gram-positive cocci, such as MRSA, PRSP, and VRE.

Kriging 해석에 의한 한강유역 호우의 공간분포 특성

이재형,박영기,김민환 全北大學校 1988 論文集 Vol.30 No.-

Rainfall is a phenomenon that shows a high variablity both in space and time. Hydrogists are usually intersted in the description of the spatial distribution of rainfall over watershed during a period of time. To determine the spatial distribution of rainfall event over a given area, rain-gage and telemeter datas are available. Introducing the kriging theory, spatial distribution of rainfall over the Han river basin estimated as follows; (1) Interpolation of ungaged point by multiquadric equation, (2) Application of the generalized covariance concept to account for nonstationarity as measured by a polynomial drift, (3) Detrend method by estimation of the spatial correlation of the residuals using the elevation data. The procedures proposed are compared with efficiency.

석·골재의 분류 및 패턴 분류

남부희,박민현,김형배 강원대학교 부설 석재복합신소재 제품연구센터 2000 석재연 논문집 Vol.5 No.-

우리는 DWT를 적용하요 석ㆍ골재의 패턴 분류와 인식을 위한 테이타베이스를 구축하였다. 우선, 우리는 이미지의 각 row 벡터를 DWT를 수행하여 각 row 벡터마다 특징값을 얻는다. 그리고나서 같은 방법으로 row 벡터의 특징값을 이미지전체의 특징 값을 얻을 때가지 DWT를 반복해서 수행한다. 그런 다음 우리는 이미지의 히스트그램을 얻는다. 특징 값과 히스토그램은 이미지의 특징을 나타낸다. CCD 카메라로 새로운 이미지를 얻었을 때 우리는 먼저 특징 값과 히스트그램을 얻는 과정을 수행한다. 그 특징 값을 가지고 패턴 원형을 찾기 위해 저장된 특징 값과 비교하여 비슷한 값들을 찾아낸다. 그리고 입력 데이터의 히스트그램을 가지고 이전 과정에서 찾아낸 이미지들의 히스트그램과 비교하여 가장 유사한 패턴 원형을 찾아낸다. 이 방법은 석ㆍ골재의 자동분류를 할 수 있도록 하여 생상선 향상과 비용절감을 가능하게 한다. We built some database of stone and aggregate resources for classification and pattern recognition using DWT(discrete wavelet transform). First, we perform one dimensional DWT for each row of the image and obtain one value for each row of image. Then we perform again the same DWT for them to get a feature value. Next, we evaluate the histogram of input image data. The feature value and histogram represent the feature of image data. when an image data achieved by CCD camera, we perform same process again to get a feature value and a histogram. the feature value is compared with stored feature values to choose candidates. And then the histogram of input data is compared with some histogram value of candidates to find target image. this method can be adapted to automation of manufacturing of stone and aggregate resources for high quality low cost products.