표고버섯(Lentinus edodes)섭취가 streptozotocin 유발 당뇨 흰쥐의 혈당수준과 에너지원 조성에 미치는 영향

한혜경,임숙자 德成女子大學校 1996 德成女大論文集 Vol.26 No.-

The hypoglycemic effects of Lentinus edodes on streptozotocin(STZ)-induced diabetic rats were investigated. Diabetes mellitus was induced in male Sprague-Dawley rats by injections of STZ into the tail vein at a dose of 45mg/kg. The animals weighing 200-250g were fed either a control diet(AIN-76) or mushroom diets for four weeks. The body weight gain was monitored and the blood levels of glucose and cholesterol were analyzed. The levels of protein, triglyceride and free fatty acid in plasma were determined. The extent of blood glucose decrements in rats fed on Lentinus edodes was greater than that found in the STZ-control group. The plasma protein levels were not influenced, although the plasma cholesterol levels were significantly lowered in rats fed on Lentinus edodes. The levels of plasma triglyceride and free fatty acid were also significantly decreased in Lentinus edodes. The results suggest that Lentinus edodes causes a hypoglycemic effect in diabetic rats and that mushroom intake may be beneficial for the managemant of diabetes mellitus.

노인의 성 지식과 태도 및 교육요구

한혜자,김남초,지성애 성인간호학회 2003 성인간호학회지 Vol.15 No.1

knowledge, attitudes, and educational needs for sexuality of the elderly. Method: This was a descriptive study, in which data were collected from February to April 2002 from 354 elderly who were residing in Chung-Chung province. Result: 1. The level of knowledge regarding sexuality was below average. 2. The level of the attitudes toward sexuality of the elderly was neither positive nor negative. 3. The educational needs of the elderly were above average. 4. Higher level of knowledge on sexuality was significantly correlated with more positive attitudes and education needs for sexuality, and more positive attitudes toward sexuality was significantly correlated with more educational needs for sexuality. Conclusion: Particularly men, with good health, and those who were in intimate relationships with their spouses and still engaged with active sexual life showed somewhat higher level of knowledge and positive attitudes as well as higher educational needs. Therefore, further development and applying of sexuality promotion programs for healthy elder couples should be considered in the future to enhance the quality of life of elder population. In addition, it is also suggested to develop an alternative intervention program on sexuality for elderly who are women, those with meager health, and the bereaved.

일부 농촌지역 노인의 간이 영양상태 조사

한혜자,김남초 노인간호학회 2007 노인간호학회지 Vol.9 No.1

Purpose: The purpose of this study was to provide basic information for developing programs to maintain and improve the physical health of the elders living in rural areas. Methods: For this study, 200 male and female elders were selected through convenient sampling. The researchers visited the home of each elder and collected data by using the mini-nutritional assessment tool developed by Guigoz, Vellas & Garry (1996). Real numbers and percentages, means and standard deviations, t-test, ANOVA and Scheffe' test were used to analyze the data. SAS was the computer program used in this study. Results: For nutritional status, 57% of the subjects were well-nourished, 41%, at risk for malnutrition and 2%, under nutrition. However, the average score for nutritional status was satisfactory at 24.03 points. The nutritional status of the elders was different according to their gender and age. Nutritional status was better in men than in women and better for those their 60s compared to those their 70s or 80s. Conclusion: The nutritional status of elders in rural areas was assessed to be satisfactory; however, the nutritional status deteriorated as they got older. This result suggests the necessity of more thorough nutrition management for older elders by health care providers in rural areas.

비타민 E와 C의 복합섭취가 최대운동시 호흡순환기능 및 혈중 지질치에 미치는 영향

현송자,한혜정,석혜경,김귀백 東亞大學校附設스포츠科學硏究所 2001 스포츠科學硏究論文集 Vol.19 No.-

The purpose of this study is to find out the effects of compound supplement vitamins E and C on the blood lipid levels during maximal exercise. Seven subjects are high school students and have to be taken 400IU of vitamin E and 200mg of vitamin C after breakfast during 8weeks, and maximal exercise before vitamin compound supplements and after 8weeks The results of this study are as follows: 1. In maximal exercise before and after taking vitamin E-C compound supplements, oxygen uptake (V02) and METs significantly (P<.01, P<.05) increased. Ventilation (CAE) also increased significantly (P<.05), while heart rate (HR) significantly (P<.05) decreased after vitamin E-C compound supplements. 2. TG was significantly (P<.05, P<.Ol) lowered before as well as after the maximal exercise. Total cholesterol (T-C) showed significant (P<.05) decrease after the maximal exercise. HDL-C indicated significant (P<.05) increase, but LDL-C presented reduction of significance (P<.05) before and after the maximal exercise. The LDL-C/HDL-C ratio significantly (P<.Ol, P<.05) decreased before and following the training. The T-C/HDL-C ratio also retained significant (P<.05, P<.Ol) reduction both before and after the running exercise. In conclusion, the compound supplements of vitamins E and C are considered to improve the respiro-circulatory function in exhaustive exercise, decrease an LDL-C concentration, increase an HDL-C concentration and prevent arteriosclerosis.

두경부 암환자의 항암화학요법에 따른 삶의 질 변화

신혜숙,박혜자,박명희,연기순,김훈교,문한림,송혜향 가톨릭대학교 가톨릭대학교 간호대학 호스피스 교육연구소 1999 호스피스논집 Vol.4 No.-

The purpose of this study was to assess the changes in quality of life wish elapse of chemotherapy in head and neck cancer patients. This study was a longitudinal descriptive design. The subjects were 9 patients who had stage III and stage IV head and neck cancer and received neoadjuvant cisplatin and 5-fluorouracil chemotherapy. Linear Analogue Self Assessment Scale (LASA) of the QOL which it includes eleven items(seven physical items appetite, nausea/vomiting, physical well-being, vigor activity, energy, sleepiness, fatigue and four mental items anger, anxiety, depression & vital power) were used to assess the quality of life eleven times(once in the prechemotherapy period and from the 1st day to 10th day postchemotherapy). The means of scores at each time were analyzed by repealed measures of ANOVA and Bonferroni multiple comparison method. The results are as follows : 1. The degree of appetites decreased significantly on the period between third and sixth day compared with that of appetites on the prechemotherapy day (p<0.001). 2. The degree of physical well-being decreased significantly on the period between first and fifth day compared with that of physical well-being on the prechemotherapy day (p<0.001). 3. The degree of nausea/vomiting decreased significantly on the period between first and fourth day compared with that of appetites on the prechemotherapy day (p<0.001). 4. The degree of anger decreased significantly on the second, fourth, eighth and ninth day after chemotherapy compared with that of anger on the prechemotherapy day(p<0.001). 5. The degree of fatigue decreased significantly on the fourth day compared with that of fatigue on the prechemotherapy day(p<0.001). 6. The increment of nausea/vomiting and poor appetite started on the 2.89th day and 3.67th day after chemotherapy, respectively. 7. The increment of sleepiness started on the 2.56th day after chemotherapy. 8. The increment of depression and anxiety started on the 2.33th day and 3.33th day after chemotherapy, respectively. 9. The lowest degrees of nausea/vomiting and poor appetite were 37.00±17.9 % and 28.64±14.94 % after chemotherapy compared with those of nausea/vomiting and poor appetite on the prechemotherapy day, respectively. 10. The lowest degrees of anger and vigor activity were 48.12±28.3 % and 39.83±24.9 % after chemotherapy compared with those of anger and vigor activity on the prechemotherapy day, respectively. 11. The recovery rates of eight items of quality of life (appetite, vigor activity, energy, fatigue, anger, anxiety, depression & vital power) were shown to reach a peak on the tenth day after chemotherapy and be reached to almost 84 % compared with those of quality of life on the prechemotherapy day. 12. The recovery rates of physical well-being and sleepiness were shown to reach to 67.75 % and 95.68 % on the 10th day after chemotherapy compared with those of physical well-belong and sleepiness on the prechemotherapy day. 13. The recovery rates of seven physical items were faster than those of four mental items on the 10th day after chemotherapy. In conclusion, it is suggested that nursing care strategies to improve the quality of life in patients with chemotherapy would be established both physically and mentally, and be extended at least ten days when patients stayed their home after chemotherapy.

고본 Ethanol 추출물의 투여가 streptozotocin 유발 당뇨 흰쥐의 혈당 및 글리코겐 함량에 미치는 영향

임숙자,한혜경,최성숙 덕성여자대학교 자연과학연구소 2007 자연과학 논문집 Vol.13 No.-

This study was designed to examine the effects of ethanol (EtOH) extract of Angelicae tenuissimae on glucose and glycogen levels in streptozotocin (STZ) induced diabetic rats. Sprague-Dawley rats were induced diabetes mellitus by STZ injection (45 mg/kg) into the tail vein and were divided into 4 groups: normal, STZ-control, two experimental diabetic groups. EtOH extract of Angelicae tenuissimae were administered orally into the diabetic rats for 14 days. The diet intake and body weight were monitored and plasma levels of glucose, aminotransferase activity and glycogen level in liver and muscle were analyzed. Oral administration of 2.0g/kg b.w. on the EtOH extracts for 14 days resulted in a significant reduction in plasma levels of glucose, activities of ALT and AST. The glycogen levels in liver and muscle of EtOH-2 group were significantly higher than that of STZ-control group. The results show that EtOH extract of Angelicae tenuissimae could be effective to control the STZ-induced diabetic rats.

간호학생의 임상실습 교육을 위한 임상지도자 활용모델(Preceptorship Model) 적용 효과에 관한 연구

김조자,이원희,김소선,유해라,한신희,김기연,노영숙 대한간호협회 1997 대한간호 Vol.36 No.4

음경에 발생한 기저세포암 1예

이용주,최혜자,윤석권,김한욱,임철완 대한피부과학회 2004 大韓皮膚科學會誌 Vol.42 No.3

Basal cell carcinoma is the most common malignant skin cancer in Korea. The lesions are most frequently found in the head and neck region. But penile basal cell carcinoma is very rare and there are only 29 other reported cases. We report a rare case of basal cell carcinoma of the penis in a 76-year-old man. He had a well circumscribed 1.3㎝×1.3㎝ thick scaly plaque with central ulcer in right penile root area for 4 years. The lesion was completely excised and no recurrence for four months. (Korean J Dermatol 2004;42(3):350~352)

항전시기 한국청년전지공작대의 항일예술활동

한혜자(Han, Hye-Ja) 역사학연구소 2016 역사연구 Vol.- No.30

In the period of resistance to Japan, The Korean youths battlefield mission corps (韓國靑年戰地工作隊) which acted mainly in Xian(西安), China was a representative Korean armed group belonging to anarchism. They were associated with Hu Jong-nan(胡宗南), the commander in chief of the 34th Corps of Chinese army. And then they concentrated on expansion of armed capability in the Korean youths training class(韓國靑年訓練班) established in Gansadan in the 34th Corps. They actively developed cultural propaganda activity through performance of anti-Japan artistic play while strengthening tie between Gansadan and women’s society in Xian. In the process, joining of Han Yu-han who was an instructor and a figure in the artistic realm became an opportunity to encourage cultural propaganda activity of The Korean youths battlefield mission corps. In May 1940, The Korean youths battlefield mission corps performed opera <Arirang>, paper-picture show <night in the national border>, <a Korean soldier> and delivered some 4,100 Won from profits to women’s society. Since then, opera <Arirang> had been performed several times in some places including Xian and became a representative work showing anti-Japan consciousness of Korean people. In addition, this contributed to change of consciousness for tie between Korea and China by Chinese army and civilians. Han Yu-han taking charge of essential role of cultural propaganda activity in The Korean youths battlefield mission corps was invited as a chief of children art class of Shanxi wartime the second nursery school(陝西省戰時第二保育院) which is a Chinese organization in the late 1942. Then times, children artistic class activity of Han Yu-han was used in cultural propaganda activity of Korea and China, working as medium to connect two countries. Even with limitation of activity in China, The Korean youths battlefield mission corps pursued mutual cooperation in the equal relationship with China. Han Yu-han made such idea possible. Anti-Japan artistic activity of The Korean youths battlefield mission corps contributed to inspiration of resistance consciousness and practice of such resistance by Korea and China.

Clinical characterization of a Korean case with 3p25 deletion

Hye Jin Lee,Ja Hye Kim,Ja Hyang Cho,Beom Hee Lee,Jin Ho Choi,Han Wook Yoo 대한의학유전학회 2014 대한의학유전학회지 Vol.11 No.1

Chromosome 3 (3p) deletion syndrome is a rare genomic disorder caused by a deletion at the terminal end of the short arm of chromosome 3. The primary characteristics of the syndrome are delayed development, dysmorphic features, and several other congenital anomalies. Here, we describe the case of a 2-year-old Korean girl with typical features of 3p deletion syndrome, including dysmorphic facial features, low birth weight, developmental delay, growth and cognitive retardation, and congenital heart disease. This case represents the first report of 3p deletion syndrome in Korea. Although phenotypes can be variable among patients, a clinically recognizable pattern has been described for this genetic defect, and our report helps to identify other cases with 3p deletion syndrome from a clinical and genetic perspective.