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      • 시멘트 제조사 및 W/C 변화에 따른 콘크리트의 초기 강도발현 특성

        金光華,裵正烈,김규도,이승훈,한천구 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(구조계)

        This study is to investigate the influence of cement manufacturing company and W/C on the properties of fresh concrete, strength of hardened concrete and rebound value of P type Schmidt hammer. According to the result, setting time of concrete is shortened with and increase of W/C, and when cement made in A and B corporation is used in concrete, the final setting time is measured at about 10 hours and 13 hours. Compressive strength increases with elapse of time and decrease of W/C, and concrete using cement made in A corporation shows higher compressive strength and rebound value until 24 hours, but from 3rd day, the contrary tendency is shown. As for the properties of early strength, the strength develop fast with decrease of W/C, and the time when compressive strength of 5MPa is gained and the form can be removed, is about 15, 18, 21 hours and 20, 22, 27 hours at the W/C 40, 45, 50% in concrete using cement made in A and B Co. respectively. The correlativity between compressive strength and the rebound value, which a coefficient of correlation is over 0.97, is very favorable. Therefore this method is effective to estimate the strength of removing the form.

      • KCI등재

        Intranasally Administered Adjunctive Dexmedetomidine Reduces Perioperative Anesthetic Requirements in General Anesthesia

        Zheng Chen,Xiang Wu,Li-Hua Hang,Hong Wang,Dong-Hua Shao,Yi-Guo Xu,Wei Cui 연세대학교의과대학 2016 Yonsei medical journal Vol.57 No.4

        Purpose: Intranasal dexmedetomidine is an effective sedative for premedication and is regularly used to reduce preoperative tension and anxiety in children. This study aimed to assess the effect of intranasally adjunctive dexmedetomidine on perioperativesedative and analgesic requirements in adults. Materials and Methods: Patients were randomly divided into four groups to receive preoperative administration of saline, intranasaldexmedetomidine 1 μg/kg and 2 μg/kg, and intravenous dexmedetomidine 1 μg/kg, respectively. Propofol and remifentanil were target-controlled infused to maintain intraoperative bispectral index at 45–55 and blood pressure at baseline value±20%. Sufentanil was administered to maintain postoperative visual analogue scale ≤3. Perioperative anesthetics requirements were compared using nonparametric tests. Results: Intranasal dexmedetomidine significantly attenuated propofol requirements for anesthesia induction and maintenance in a dose-dependent manner. Patients given intranasal dexmedetomidine 2 μg/kg required less remifentanil for anesthesia maintenance. The first postoperative request for sufentanil analgesia was delayed in patients given intranasal dexmedetomidine 2 μg/kg. The anesthetics-sparing effect of intranasal dexmedetomidine was significantly weaker than intravenous dexmedetomidine at the same dose of 1 μg/kg. The incidences of adverse events, including hemodynamic instability and delayed recovery, were comparablewith and without intranasal dexmedetomidine. Conclusion: Intranasal administration of dexmedetomidine can reduce perioperative anesthetic requirements, and a dose of dexmedetomidine 2 μg/kg produces a better effect in adults. The anesthetics-sparing effect of intranasal dexmedetomidine 1 μg/kg is less than that with the same intravenous dose of dexmedetomidine.

      • Expression of Transcription Factor FOXC2 in Cervical Cancer and Effects of Silencing on Cervical Cancer Cell Proliferation

        Zheng, Chun-Hua,Quan, Yuan,Li, Yi-Yang,Deng, Wei-Guo,Shao, Wen-Jing,Fu, Yan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.4

        Objective: Forkhead box C2 (FOXC2) is a member of the winged helix/forkhead box (Fox) family of transcription factors. It has been suggested to regulate tumor vasculature, growth, invasion and metastasis, although it has not been studied in cervical cancer. Here, we analyzed FOXC2 expression in cervical tissues corresponding to different stages of cervical cancer development and examined its correlation with clinicopathological characteristics. In addition, we examined the effects of targeting FOXC2 on the biological behavior of human cervical cancer cells. Methods: The expression of FOXC2 in normal human cervix, CIN I-III and cervical cancer was examined by immunohistochemistry and compared among the three groups and between cervical cancers with different pathological subtypes. Endogenous expression of FOXC2 was transiently knocked down in human Hela and SiHa cervical cells by siRNA, and cell viability and migration were examined by scratch and CCK8 assays, respectively. Results: In normal cervical tissue the frequency of positive staining was 25% (10/40 cases), with a staining intensity (PI) of $0.297{\pm}0.520$, in CIN was 65% (26/40cases), with a PI of $3.00{\pm}3.29$, and in cancer was 91.8% (68/74 cases), with a PI of $5.568 {\pm}3.449$. The frequency was 100% in adenocarcinoma (5/5 cases) and 91.3% in SCCs (63/69 cases). The FOXC2 positive expression rate was 88.5% in patients with cervical SCC stage I and 100% in stage II, showing significant differences compared with normal cervix and CIN. With age, pathologic differentiation degree and tumor size, FOXC2 expression showed no significant variation. On transient transfection of Hela and SiHa cells, FOXC2-siRNA inhibition rates were 76.2% and 75.7%; CCK8 results showed reduced proliferation and relative migration (in Hela cells from $64.5{\pm}3.16$ to $49.5{\pm}9.24$ and in SiHa cells from $60.1{\pm}3.05$ to $44.3{\pm}3.98$) (P < 0.05). Conclusion: FOXC2 gene expression increases with malignancy, especially with blood vessel hyperplasia and invasion degree. Targeted silencing was associated with reduced cell proliferation as well as invasion potential.

      • KCI등재

        Separation of arenols from a low-temperature coal tar by liquid-liquid extraction

        Hua-Shuai Gao,Zhi-Min Zong,Zheng Yang,Dao-Guang Teng,Xiu-Hua Sun,Li Yan,Xian-Yong Wei,Qing-Jie Guo,Tian-Sheng Zhao,Hong-Cun Bai 한국화학공학회 2020 Korean Journal of Chemical Engineering Vol.37 No.5

        Low-temperature coal tar (LTCT) is a sticky liquid mixture produced mainly from coal pyrolysis, which contains various value-added chemicals (VACs). Liquid-liquid extraction is considered as one of the green and effective ways to explore the organic composition and separate the VACs from LTCT. Herein, petroleum ether, methanol, and carbon disulfide were used to extract arenols from a LTCT. As a result, the relative content and absolute content of arenols extracted from the LTCT are ca. 96.3% and 85.9%, respectively. Among them, p-cresol is predominant, accounting for 22.2%. The isolated contents of arenols are up to 84.6%. Moreover, a kilogram-scale operation was carried out under the same conditions, which offers a potential application in industrial production.

      • Gemcitabine in Treating Patients with Refractory or Relapsed Multiple Myeloma

        Zheng, Hua,Yang, Fan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.21

        Background: Patients with refractory or relapsed multiple myeloma are considered to have a very poor prognosis, and new regimens are needed to improve the outcome. Gemcitabine, a nucleoside antimetabolite, is an analog of deoxycytidine which mainly inhibits DNA synthesis through interfering with DNA chain elongation and depleting deoxynucleotide stores, resulting in gemcitabine-induced cell death. Here we performed a systemic analysis to evaluate gemcitabine based chemotherapy as salvage treatment for patients with refractory and relapsed multiple myeloma. Methods: Clinical studies evaluating the impact of gemcitabine based regimens on response and safety for patients with refractory and relapsed multiple myeloma were identified by using a predefined search strategy. Pooled response rate (RR) of treatment were calculated. Results: In gemcitabine based regimens, 3 clinical studies which including 57 patients with refractory and relapsed multiple myeloma were considered eligible for inclusion. Systemic analysis suggested that, in all patients, pooled RR was 15.7% (9/57) in gemcitabine based regimens. Major adverse effects were hematologic toxicity, including grade 3 or 4 anemia, leucopenia and thrombocytopenia i. No treatment related death occurred with gemcitabine based treatment. Conclusion: This systemic analysis suggests that gemcitabine based regimens are associated with mild activity with good tolerability in treating patients with refractory or relapsed multiple myeloma.

      • The Study about the Bluetooth Communication

        Zheng hua Song,Hyun sik Shin,Chun Suk Kim 한국전자통신학회 2007 한국전자통신학회 논문지 Vol.2 No.3

        Bluetooth is a standard for short range, low power, low cost wireless communication that uses radio technology. This paper presents an overview of Bluetooth communication the following article will focus on the formation of Bluetooth scatter nets and some proposed scatter net models.

      • KCI등재

        Study on the Legal Issues of the jurisdiction to arrest ships and the substantive jurisdiction of maritime case

        Zheng Hua,지상규 사단법인 한국법이론실무학회 2023 법률실무연구 Vol.11 No.1

        Arrest of ships is one of the most distinctive legal systems in the maritime field. In the process of arresting ships, there may be two kinds of jurisdictions involved, one is the jurisdiction to arrest ships, and the other is the substantive jurisdiction of maritime case. There are different view in common law and civil law countries as to "whether the court arresting a ship can acquire the substantive jurisdiction of maritime case because of the arrest of the ship involved".In order to coordinate the differences between the two legal systems on this issue,<International Convention Relating to the Arrest of Sea-Going Ships 1952>,<Hamburg Rules> and <International Convention on Arrest of Ships 1999> have stipulated the relationship between the jurisdiction to arrest ships and the substantive jurisdiction of maritime case, which has made a positive exploration to ease jurisdictional conflicts of international maritime action. However, due to the limitations of international conventions, legislative differences between different countries and forum shopping of maritime claimant, the jurisdictional conflicts of international maritime action is still serious. This paper analyzes the development history of the relationship between the jurisdiction to arrest ships and the substantive jurisdiction of maritime case by analyzing the international conventions related to the arrest of ships and the legislative status of the common law and civil law countries, and on the basis of the analysis of the legislative and judicial status of the jurisdiction to arrest ships and the substantive jurisdiction of maritime case in China, it makes several suggestions to improve the jurisdiction to arrest ships and the substantive jurisdiction of maritime case in China, namely, the Chinese courts should adhere to the principle of international comity in the judicial practice of maritime litigation, introduce the doctrine of forum non conveniens into <Special Maritime Procedure Law of the People's Republic of China>, and strengthen international judicial cooperation, in order to ease the jurisdictional conflicts between countries.

      • KCI등재

        다시마의 혐기성 소화에서 유기물 부하와 수리학적 체류시간의 영향 분석

        Zheng Hua Piao,Xin Zhao,이종근,김재영 한국폐기물자원순환학회 2014 한국폐기물자원순환학회지 Vol.31 No.5

        Seaweeds are received high attending as one of new and renewable energy sources. In this study, the effects of organic loading rate (OLR) and hydraulic retention time (HRT) on anaerobic digestion with Laminaria japonica were investigated using labrotory-scale semi-continuous stirred type reactors. The results demonstrated that anaerobic digestion of Laminaria japonica performed stably with OLRs in the range of 1.00 ~ 1.50 g-VS/L·d and HRTs in the range of 27 ~ 40 days. The maximum methane production obtained was 251.33 mL-CH4/L·d, which was achieved for an OLR of 1.50 g-VS/L·d and a HRT of 27 days. However, an OLR of 1.75 g-VS/L·d and a HRT of 23 days brought about a decrease in the pH and volatile fatty acids (VFAs) accumulation, causing the destabilization of the reactor and process failure. The reactors operated at a constant influent substrate concentration, i.e., 40 g-VS/L, thus OLR and HRT could not be treated separately and independently. According to the limited results of this study, it seems that the suitable OLR of anaerobic digestion of Laminaria japonica was lower than 1.50 g-VS/L·d and suitable HRT was higher than 27 days.

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