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      • SCOPUSKCI등재

        Submanifolds of Constant Scalar Curvature in a Space Form

        Zhong Hua Hou KYUNGPOOK UNIVERSITY 1998 Kyungpook mathematical journal Vol.38 No.1

        Let M^(n) be a closed submanifold immersed into a space formM~^(n+p)_ (c) of constant curvature c≥ 0. Denote by R the normalized scalar curvature and by H the mean curvature of M^(n) : Suppose that R is constant and R≥ c. We firstly extend Cheng-Yau's technique to higher codimension cases. Then we study the rigidity problem for M^(n) with parallel normalized mean curvature vector field. We show that, if H satisfies a certain inequality, then M^(n) is totally umbilical or the equaluity holds. We describe all M^(n) that satisfy this equality. We also prove some rigidity theorems of Yano-Ishihara's type and extend the rigidity theorems of H. Li to higher codimension. 0. Introduction

      • KCI등재
      • SCIESCOPUSKCI등재

        The effect of biogas slurry application on biomass production and the silage quality of corn

        Hua Sun,Kai Shi,Hairong Ding,Chenglong Ding,Zhiqing Yang,Chen An,Chongfu Jin,Beiyi Liu,Zhaoxin Zhong,Xia Xiao,Fuyin Hou Asian Australasian Association of Animal Productio 2023 Animal Bioscience Vol.36 No.12

        Objective: The objective of this study was to evaluate the effect of biogas slurry application on biomass production and the silage quality of corn. Methods: A field experiment was conducted in which corn was grown using different biogas slurry application rates. The effect of 25% to 500% biogas slurry nitrogen replacement (T1 to T14) on the yield and quality indices of corn were studied by field plot experiments. Results: The results revealed that biogas slurry application improved the stem diameter and relative feed value of corn silage in treatments T13 and T11. Moreover, the fermentation quality of corn silage was improved due to an increase in lactic acid content; in comparison with the chemical synthetic fertilizer (CF) group. The crude protein contents of corn silage had no obvious change with increasing biogas slurry application. However, the forage quality index of acid detergent fiber was decreased (p<0.05) in the T11 group compared with the CF group. In addition, higher (p<0.05) 30 h in vitro dry matter digestibility and 30 h in vitro neutral detergent fiber digestibility were observed in the T11 and T13 groups than in the CF group. Conclusion: Based on these results, it was concluded that the optimum biogas slurry application rate for corn was approximately 350% to 450% biogas slurry nitrogen replacement under the present experimental conditions.

      • KCI등재

        Comprehensive profiles and diagnostic value of menopausal-specific gut microbiota in premenopausal breast cancer

        Hou Ming-Feng,Ou-Yang Fu,Li Chung-Liang,Chen Fang-Ming,Chuang Chieh-Han,Kan Jung-Yu,Wu Cheng-Che,Shih Shen-Liang,Shiau Jun-Ping,Kao Li-Chun,Kao Chieh-Ni,Lee Yi-Chen,Moi Sin-Hua,Yeh Yao-Tsung,Cheng Chi 생화학분자생물학회 2021 Experimental and molecular medicine Vol.53 No.-

        In Western countries, breast cancer tends to occur in older postmenopausal women. However, in Asian countries, the proportion of younger premenopausal breast cancer patients is increasing. Increasing evidence suggests that the gut microbiota plays a critical role in breast cancer. However, studies on the gut microbiota in the context of breast cancer have mainly focused on postmenopausal breast cancer. Little is known about the gut microbiota in the context of premenopausal breast cancer. This study aimed to comprehensively explore the gut microbial profiles, diagnostic value, and functional pathways in premenopausal breast cancer patients. Here, we analyzed 267 breast cancer patients with different menopausal statuses and age-matched female controls. The α-diversity was significantly reduced in premenopausal breast cancer patients, and the β-diversity differed significantly between breast cancer patients and controls. By performing multiple analyses and classification, 14 microbial markers were identified in the different menopausal statuses of breast cancer. Bacteroides fragilis was specifically found in young women of premenopausal statuses and Klebsiella pneumoniae in older women of postmenopausal statuses. In addition, menopausal-specific microbial markers could exhibit excellent discriminatory ability in distinguishing breast cancer patients from controls. Finally, the functional pathways differed between breast cancer patients and controls. Our findings provide the first evidence that the gut microbiota in premenopausal breast cancer patients differs from that in postmenopausal breast cancer patients and shed light on menopausal-specific microbial markers for diagnosis and investigation, ultimately providing a noninvasive approach for breast cancer detection and a novel strategy for preventing premenopausal breast cancer.

      • KCI등재

        Compressive Deformation Behavior of AZ31Mg Alloy Containing {10–12} Extension Twins at Different Temperature

        Hua Zhang,Xiaoqing Bai,Minjian Hou,Lifei Wang,Qiang Zhang,Jianfeng Fan,Weiguo Li,Hongbiao Dong,Bingshe Xu 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.5

        Influence of pre-introducing {10–12} extension twins on compressive deformation behavior of AZ31Mg alloy at differenttemperature was investigated. The compression tests were conducted along the normal direction of AZ31Mg alloy at roomtemperature, 100 °C, 200 °C and 300 °C with a strain rate of 1 × 10−3 s−1. The results indicated that the pre-introducing{10–12} extension twins strongly affected the yield strength, the peak strength and the strain hardening rate at middle-lowtemperature (≤ 200 °C). The twinned samples containing pre-introducing {10–12} extension twins exhibited smaller yieldstrength and larger peak strength than the as-received samples without {10–12} extension twins at temperature ≤ 200 °C. Forthe as-received samples, the strain hardening rate decreased gradually at different temperature. While for the twinned samples,the strain hardening behavior exhibited three distinct stages at temperature ≤ 200 °C. When compressing at 300 °C, the asreceivedand twinned samples exhibited similar compression flow curves and strain hardening rate curves. The continuousdynamic recrystallization (CDRX) was the main dynamic recrystallization (DRX) mechanism in the as-received sample whencompressing at 200 °C. The twin assisted DRX besides CDRX was also initiated in the twinned sample when compressingat 200 °C. While the DRX mechanism was transformed into the discontinuous dynamic recrystallization (DDRX) in boththe as-received and twinned samples when compressing at 300 °C.

      • Antitumor Effects of Hyperthermic CO<sub>2</sub> Pneumoperitoneum on Human Gastric Cancer Cells

        Zhou, Hou-Min,Feng, Bo,Zhao, Hong-Chao,Zheng, Min-Hua Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.1

        Aim: To elucidate the effects of hyperthermic $CO_2$ pneumoperitoneum on human gastric AGS cells. Methods: Based on a newly devised in vitro study model, we evaluated the anti-cancer effects of HT-$CO_2$ ($42-44^{\circ}C$ for 2-4h) on human gastric cancer cells, and also the corresponding mechanisms. Results: HT-$CO_2$ ($42-44^{\circ}C$ for 2-4h) severely inhibited cell proliferation as assessed by Cell Counting Kit-8 assay, while inducing apoptosis in a temperature- and time-dependent manner demonstrated by annexin-V/PI flow cytometry and morphological analysis (Hoechst/PI fluorescence). In addition, it was found that HT-$CO_2$ ($42-44^{\circ}C$ for 2-4h) promoted the up-regulation of Bax by western blotting. Significantly, it could also suppress gastric cancer cell invasion and metastasis by in vitro invasion and motility assay. Conclusion: In conclusion, HT-$CO_2$ had an efficacious cytotoxic effect on gastric cancer cells through Bax-induced mitochondrial apoptotic signaling. Our studies indicate that it may serve as a potential therapy for peritoneal carcinomatosis of gastric cancer. Further investigations in vivo using animal models are now urgently needed.

      • KCI등재

        Case of Pulmonary Cryptococcosis Mimicking Hematogeneous Metastases in an Immuocompetent Patient: Value of Absent 18F-Fluorodeoxylucose Uptake on Positron Emission Tomography/CT Scan

        Chiao-Hua Lee,Ching Tzao,Tsun-Hou Chang,Wei-Chou Chang,Guo-Shu Huang,Chih-Kung Lin,Hsin-Chung Lin,Hsian-He Hsu 대한영상의학회 2013 Korean Journal of Radiology Vol.14 No.3

        The radiologic appearance of multiple discrete pulmonary nodules in immunocompetent patients, with cryptococcal infection, has been rarely described. We describe a case of pulmonary cryptococcosis, presenting with bilaterally and randomly distributed nodules on a computed tomography, mimicking hematogeneous metastases. Positron emission tomography does not demonstrate 18F-fluorodeoxyglucose (FDG) uptake, suggesting a low probability for malignancy, which is a crucial piece of information for clinicians when making a management decision. We find the absence of FDG uptake correlates with the pathologic finding of an infectious nodule, composed of fibrosis and necrosis.

      • KCI등재

        In Vivo Detection of Lipid-Core Plaques by Coronary CT Angiography: A Head-to-Head Comparison with Histologic Findings

        Wei-hua Yin,Yan Zhang,Xiang-nan Li,Hong-yue Wang,Yun-qiang An,Yang Sun,Zhi-hui Hou,Yang Gao,Bin Lu,Zhe Zheng 대한영상의학회 2020 Korean Journal of Radiology Vol.21 No.2

        Objective: We sought to distinguish lipid plaques using a CT quantitative pixel density histogram, based on the pathological diagnosis of lipid cores as the gold standard. Materials and Methods: Eight patients awaiting heart transplantation due to end-stage coronary heart disease underwent coronary CT angiography (CCTA) spectroscopy prior to heart transplantation; coronary artery pathological analysis was performed for all patients. Lipid-core plaques were defined pathologically as manifesting a lipid core diameter > 200 μm, a circumference > 60 degrees, and a cap thickness < 450 μm. The percentage distributions of CT pixel attenuation ≤ 20, 30, 40, and 50 HU were calculated using quantitative histogram analysis. Results: A total of 271 transverse sections were co-registered between CCTA and pathological analysis. Overall, 26 lipid cores and 16 fibrous plaques were identified by pathological analysis. There was no significant difference in median CT attenuation between the lipid and fibrous plaques (51 HU [interquartile range, 46–63] vs. 57 HU [interquartile range, 50–64], p = 0.659). The median percentage of CT pixel attenuation ≤ 30 HU accounted for 11% (5–17) of lipid-core plaques and 0% (0–2) of fibrous plaques (p < 0.001). The sensitivity and specificity of the method for diagnosing lipid plaques by the average CT pixel attenuation ≤ 30 HU were 80.8% and 87.5%, respectively. The area under the receiver operator characteristics curve was 0.898 (95% confidence interval: 0.765–0.970; 3.0% was the best cut-off value). The diagnostic performance was significantly higher than those of the average pixel CT attenuation percentages ≤ 20, 40, and 50 HU and the mean CT attenuation (p < 0.05). Conclusion: In in vivo conditions, with the pathological lipid core as the gold standard, quantification of the percentage of average CT pixel attenuation ≤ 30 HU in the histogram can be useful for accurate identification of lipid plaques.

      • KCI등재

        書評 : 口述史的佳作 -評習賢德敎授撰寫的<<警察與二二八事件>>

        ( Jie Hou ),( Shao Hui Hua ) 중국사학회 2014 中國史硏究 Vol.88 No.-

        2012年7月, 習賢德敎授撰寫的『警察與二二八事件』一書在臺灣由時英出版社出版, 引起筆者的關注. 早在2006年筆者訪學於臺灣大學時, 曾和習敎授有過短暫交往. 2008年筆者訪學世新大學舍我紀念館期間, 與習敎授學術交流增多, 逐漸瞭解他是一位曾在新聞界打□多年, 後又轉向學界, 透過勤苦治學, 取得諸多成績的成大事者. 俗話說"十年磨一劍". 『警察與二二八事件』一書可以說是現爲臺灣輔仁大學大□傳播學硏究所副敎授兼新聞傳播學系主任和傳播學院行政副院長的習賢德敎授花費大量心血完成的精心之作. 在10多年前, 他卽開始拜訪1945年10月赴臺灣接收警務幷親歷"二二八事件"的國民黨中央警校臺灣幹部訓練班(以下簡稱"台幹班")的菁英, 幷完成了珍貴的口述史著作. 2007年, 習賢德敎授憑藉這部口述史的學術硏究成果--『二二八口述歷史補遺: 中央警校台幹班的集體記憶』一書獲得了美國紐約第15屆"萬人傑新聞文化奬", 頒奬委員會認定該書的價値在於"澄淸歷史疑點, 揭開事實眞相". 『警察與二二八事件』正是在上述一書的基礎上經過著者的逐段考據幷進行增補後出版發行的, 是近年來硏究和再認識"二二八事件"的一部口述史佳作.

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