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      • KCI등재

        Research on 3D Human Motion Capture Algorithm for Online Physical Education Teaching

        Weiguo Li,Yongli Yang,Jing Zhou,Zhipeng Li 대한전자공학회 2023 IEIE Transactions on Smart Processing & Computing Vol.12 No.2

        This study proposes to use the gradient descent method in data fusion to solve the problem of low learning efficiency of online sports courses by optimizing the attitude calculation and combining gait detection and zero speed correction to form a three-dimensional human motion capture system. The system was applied to online physical education teaching to improve teaching quality. The performance of the optimized attitude calculation algorithm and the Kalman filter algorithm was compared. The results show that the error angle of the data-fusion-attitude calculation algorithm was 1.67°, which is better than the Kalman filter algorithm. In the empirical analysis of the 3D human motion capture system designed by the research, the system could correctly capture the real human motion trajectory. Moreover, comparative analysis of the online physical education courses showed that the satisfaction of the online physical education courses embedded in the system was 90.62, which was much higher than other online physical education courses. These results show that the optimized attitude calculation algorithm can better capture real human movements, and the human motion capture system composed of this can improve the learning effect of online physical education courses. This method opens up new ideas for online physical education teaching.

      • KCI등재

        Dynamic stiffness analysis of steel-concrete composite beams

        Jun Li,Qiji Huo,Xiaobin Li,Xiangshao Kong,Weiguo Wu 국제구조공학회 2014 Steel and Composite Structures, An International J Vol.16 No.6

        An exact dynamic stiffness method is introduced for investigating the free vibration characteristics of the steel-concrete composite beams consisting of a reinforced concrete slab and a steel beam which are connected by using the stud connectors. The elementary beam theory is used to define the dynamic behaviors of the two beams and the relative transverse deformation of the connectors is included in the formulation. The dynamic stiffness matrix is formulated from the exact analytical solutions of the governing differential equations of the composite beams in undamped free vibration. The application of the derived dynamic stiffness matrix is illustrated to predict the natural frequencies and mode shapes of the steel-concrete composite beams with seven boundary conditions. The present results are compared to the available solutions in the literature whenever possible.

      • An Epidemic Model of Information Dissemination in Mobile Social Networks

        Wang Weiguo,Chu Chen,Liu Jinzhuo,Li Tairan 보안공학연구지원센터(IJUNESST) 2015 International Journal of u- and e- Service, Scienc Vol.8 No.1

        In this paper, we propose a new model for information dissemination in mobile social networks. The dynamic equation of information dissemination is modified. Moreover, we investigate numerically the behavior of the model on a real scale-free social site with the exponent γ =1.08. We find that initial spreaders with big out-degree of can accelerate information dissemination, and the nodes with large in-degree would be easier to be a spreader or to become to stiflers.

      • KCI등재

        CircRNA circ_0067772 aggravates the malignant progression of cutaneous squamous cell carcinoma by regulating miR‑1238‑3p/ FOXG1 axis

        Xiaoqing Li,Yinghui Kong,He Li,Manyuan Xu,Ming Jiang,Weiguo Sun,Suping Xu 한국유전학회 2021 Genes & Genomics Vol.43 No.5

        Background Cutaneous squamous cell carcinoma (CSCC) is a severe malignancy derived from skin. Dysregulated circular RNAs (circRNAs) might play vital roles in tumor development. Objective Here, we aimed to explore the function of a novel circRNA circ_0067772 in CSCC. Methods Quantitative real-time PCR (qRT-PCR) or Western blot assay was performed to determine the expression of circ_0067772, microRNA (miR)-1238-3p and forkhead box protein G1 (FOXG1). Cell proliferation was assessed by Cell Counting Kit-8 (CCK-8) assay and colony formation assay. Transwell assay and wound healing assay were employed to examine cell metastasis. Flow cytometry was employed to monitor cell cycle and apoptosis. The target association between miR-1238-3p and circ_0067772 or FOXG1 was validated by dual-luciferase reporter assay. Moreover, role of circ_0067772 in vivo was investigated via xenograft model in nude mice. Results Circ_0067772 and FOXG1 were upregulated, while miR-1238-3p was downregulated in CSCC tissues and cells. Circ_0067772 knockdown conferred inhibitory efects on cell proliferation, migration and invasion of CSCC cells. MiR1238-3p served as a target of circ_0067772, whose silencing could reverse circ_0067772 knockdown-induced inhibitory impact on the malignant cellular behaviors. Circ_0067772 positively regulated FOXG1 expression by antagonizing miR1238-3p. Additionally, miR-1238-3p could repress CSCC cell proliferation, migration and invasion by targeting FOXG1. Also, circ_0067772 knockdown hindered CSCC tumor growth in vivo. Conclusion Our study identifed a novel oncogenic circRNA and the involvement of circ_0067772/miR-1238-3p/FOXG1 axis in CSCC development, providing a target for CSCC therapy.

      • KCI등재

        Emergy analysis-based study of the sustainable development of Kunming’s urban eco-economic system

        Li Hui,Cao Lei,Chen Youbin,Qiu Huiyi,Huang Xue,Guo Wanqi,Wang Shuntao,Sheng Weiguo,Zhou Yilu,Xu Qing 서울시립대학교 도시과학연구원 2023 도시과학국제저널 Vol.27 No.2

        We studied Kunming’s urban eco-economic system’s evolution from 2009 to 2018, using the emergy theory and method; with the entropy evaluation method, we analyzed the system’s natural, social and economic subsystems to know its sustainable development capacity. The results show that the system’s emergy structure has clearly improved, and its renewable resources’ emergy has been rationally employed. The environment load ratio, after reaching its peak in 2011, has been decreasing, and the environment stress has becoming lower year by year, as is conducive to sustainable development. Its eco-economic system, however, is highly dependent on the internal resources; its emergy self-sufficiency ratio indicates that it does not see sufficient utilization of imported emergy and feels excessive stress on its internal resources. It witnesses relatively high emergy intensity. The current population is about twice of its renewable resources’ population carrying capacity, and its dramatically growing population is presenting even high pressure on its social subsystems. This indicates that the living standard per capita in Kunming is lower than the national average. All of these factors will hinder the sustainable development of Kunming’s urban eco-economic system. Our analysis of attribute classification shows that it is more appropriate to calculate the tourist revenue by taking into account export emergy. At the same time, the analysis results of sustainable development emergy indexes obtained by ESI, EISD, euehi, euehi’ and entropy method are compared, which shows that the entropy method is able to better reflect the dynamic changes of the sustainable development capacity of its urban eco-economic system because it introduces all indicators of social, economic and natural subsystems for evaluation. In a word, sustainable development capacity represents the outcome of tradeoff and coordination of the three subsystems of society, economy and nature, and we can formulate corresponding strategies based on the above research findings.

      • KCI등재

        Low Carbon Concrete Prepared with Scattering-Filling Coarse Aggregate Process

        Weiguo Shen,Chuan Zhang,Xinling Li,Hua Shi,Guiming Wang,Xiaowu Tian 한국콘크리트학회 2014 International Journal of Concrete Structures and M Vol.8 No.4

        The volume fraction of the coarse aggregate in the conventional plastic concrete is controlled relatively low to ensure a required workability. In this paper, a new type of coarse aggregate interlocking concrete with strength ranging from C30 to C80 was prepared with scattering-filling aggregate process. The strength of concrete prepared with this method increases obviously whereas the shrinkage decreases significantly, the cement dosage in the concrete decreased 20 % at the same time. The microhardness of the ITZ between the cement paste and scattering-filling aggregate is higher than that of the original aggregate, the ITZ become narrower and tighter also. The interlocking and more even distribution of the coarse aggregate and the water absorption of the addition of extra amount of coarse aggregates contribute to the strength and performance improvement of the concrete prepared with scattering-filling aggregate process.

      • Role of Tie Strength in Information Dissemination in Mobile Social Networks

        Wang Weiguo,Chu Chen,Liu Jinzhuo,Li Tairan 보안공학연구지원센터 2015 International Journal of u- and e- Service, Scienc Vol.8 No.3

        In this paper, we propose a new model for information dissemination in mobile social networks, in which the infectious probability is defined as a function of the homogeneity and heterogeneity between nodes. Moreover, we investigate numerically the behavior of the model on a real scale-free social site with the exponent γ =1.08. We find that weak ties between nodes play an important role in information dissemination process. Specially, selecting weak ties preferentially can make information spread faster and wider, and the efficiency of diffusion will be greatly affected after removing them.

      • KCI등재

        The management of hydatidiform mole with lung nodule: a retrospective analysis in 53 patients

        Xiao Li,Yaping Xu,Yuanyuan Liu,Xiaodong Cheng,Xinyu Wang,Weiguo Lu,Xing Xie 대한부인종양학회 2019 Journal of Gynecologic Oncology Vol.30 No.2

        Objective: To investigate the significance of lung nodule in hydatidiform mole, we retrospectively compared the clinical outcomes of those patients treated with different strategies. Methods: The patients were divided into three groups: chemotherapy immediately once lung nodule was detected (group 1, n=17), delayed chemotherapy until human chorionic gonadotrophin (hCG) level met the diagnostic criteria for gestational trophoblastic neoplasia (GTN) (group 2, n=18), and hCG surveillance alone until hCG level was normalized spontaneously (group 3, n=18). The clinical parameters of these patients were collected and analyzed. Results: Totally 53 (4.0%) patients were included from 1,323 cases with molar pregnancy during past 16 years. Among them, the diameters of lung nodules were 0.3–2.5 cm. Chemotherapy cycles for achieving hCG normalization and the failure rate of first-line chemotherapy in group 1 were significantly increased than that in group 2 (5 vs. 3 cycles, p=0.000, 58.8% vs. 11.1%, p=0.005). The hCG level of all 18 cases in group 3 was normalized spontaneously within 6 months. Of those, lung nodules of 9 patients disappeared spontaneously, accounting for 25% (9/36) of patients who initially selected observation. The proportion of single nodule in group 3 was significantly higher than that in group 2 (10/18 vs. 2/18, p=0.012). Conclusion: Our results suggest that lung nodule alone is not an adequate indication of chemotherapy in molar pregnancy. hCG surveillance is safe for patients with lung nodule, especially with single nodule, as long as their hCG levels do not meet International Federation of Gynecology and Obstetrics diagnostic criteria for GTN.

      • SCOPUSKCI등재

        Identification of miR-23a as a novel microRNA normalizer for relative quantification in human uterine cervical tissues

        Shen, Yuanming,Li, Yang,Ye, Feng,Wang, Fenfen,Wan, Xiaoyun,Lu, Weiguo,Xie, Xing Korean Society for Biochemistry and Molecular Bion 2011 Experimental and molecular medicine Vol.43 No.6

        Quantitative real-time RT-PCR (RT-qPCR) is being widely used in microRNA expression research. However, few reports detailed a robust identification and validation strategy for suitable reference genes for normalisation in microRNA RT-qPCR studies. The aim of this study was to identify the most stable reference gene(s) for quantification of microRNA expression analysis in uterine cervical tissues. A microarray was performed on 6 pairs of uterine cervical tissues to identify the candidate reference genes. The stability of candidate reference genes was assessed by RT-qPCR in 23 pairs of uterine cervical tissues. The identified most stable reference genes were further validated in other cohort of 108 clinical uterine cervical samples: (HR-HPV- normal, n = 21; HR-HPV+ normal, n = 19; cervical intraepithelial neoplasia [CIN], n = 47; cancer, n = 21), and the effects of normalizers on the relative quantity of target miR-424 were assessed. In the array experiment, miR-26a, miR-23a, miR-200c, let-7a, and miR-1979 were identified as candidate reference genes for subsequent validation. MiR-23a was identified as the most reliable reference gene followed by miR-191. The use of miR-23a and miR-191 to normalize expression data enabled detection of a significant deregulation of miR-424 between normal, CIN and cancer tissue. Our results suggested that miR-23a and miR-191 are the optimal reference microRNAs that can be used for normalization in profiling studies of cervical tissues; miR-23a is a novel microRNA normalizer.

      • KCI등재

        NEW BOUNDS FOR PERRON ROOT OF A NONNEGATIVE MATRIX

        Chen, Jinhai,Li, Weiguo 한국전산응용수학회 2007 Journal of applied mathematics & informatics Vol.23 No.1

        In this paper, we obtain some new bounds for Perron root of a nonnegative matrix, which are expressed by easily calculated function in element of matrix. These new results generalize and improve the bounds of G. Frobenius [1] and H. Minc [2], and also extend the known results by Liu [6].

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