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      • KCI등재

        유년기 안구적출술 및 방사선치료로 인하여 발생된 안와 열성장에 대한 재건 치험례

        홍관석,김성문,김훈,임재석,최미숙,최성원,권종진 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.1

        There are many reports of the surgical management for the craniofacial abnormalities arising from the irradiation of the head and face for treatment of childhood cancers. Since the mordern combined-modality theraphy for childhood cancers began in the late 1960s and the early 1970s, recent reports have described the occular, dental and maxillo-facial abnormalities after irradiation in long-term survivors of cancers of the head and face. The resultant deformities may be known to be difficult to reconstruct with surgical techniques. This paper describes the late reconstructive surgery for the unilateral orbital and malar hypoplasia after eyeball enucleation and irradiation during childhood to correct the facial asymmetry and expand the contracted orbital socket into the functional dimension for the retaining eyeball prosthesis with spherical implant. We reports the satisfactory preliminary results from the midfacial osteotomy through the supero-lateral orbital rim and malar bone and the antero-lateral repositioning with the autogenous bone grafting in 26 year-old female patient who will be planned to make the new eyeball prosthesis by the department of ophthalmology.

      • 男·女中學生의 步行狀態分析

        洪盛杓,田寬錫 忠南大學校體育科學硏究所 1985 體育科學硏究誌 Vol.3 No.1

        The walking styles of 402 middle school students (male:218, female 184)were analyzed to provide basic, reference data for a right walking guidance. The author reached the following conclusions. 1. The left foot stepped more inside than the right one in the walking angle. 2. The girls stepped more inside than the boys. 3. The walking angle of the middle school students varied less, but were greater than those of the elementary ones. 4. Among the middle school students, boys had the longer vertical distance between both steps than girls, but this was not the case among elementary students. 5. The vertical distance between both steps of the middle school students was 1.00cm, 0.33cm longer in boys and in girls, respectively than those of the elementary students. 6. Through the aging the walking styles of the students varied from normal or step-inside group to step-outside. 7. Among the 27 walking styles, the style of walking with more than 0.5cm distance between both steps, with parallel steps, with stepping foot-inside, with stepping foot-outside, and with stepping right foot-parallel and left foot-inside was general, specifically among boys.

      • 成長期 어린이의 步行狀態分析

        田寬錫,洪盛杓 忠南大學校體育科學硏究所 1984 體育科學硏究誌 Vol.2 No.1

        In order to comprehend the walking situations of the children in a growing period and to offer basic materials for a right walking guidance, I measured and analysed the step angles and vertical difference between both steps of a primary school's students (mas.: 380 persons, fem.: 340 persons). The following results were obtained ; 1. According to the measurement of step angles and vertical difference between both steps and its analysis, there were no changes by ages. 2. In the walking angles, a right foot is more foot -outside lined than a left one, and boys are more foot - outside lined than girls. 3. Boy students walk more widely than girl students in vertical difference between both steps. 4. While walking, children whose both feet are foot- inside lined and overlap each other, and whose both feet are foot-inside and are open, are much more. 5. A walking habit of child remains unchanged up to adult.

      • Cortisone이 복막탐식세포의 탐식기능에 미치는 影響에 關한 電子顯微鏡的 硏究

        朴永寬,洪錫宰 慶北大學校 醫科大學 1972 慶北醫大誌 Vol.13 No.2

        It is well known that the phagocytic action of the cells of the reticuloendothelial system plays and important role in the immunological reaction and as a barrier against foreign bodies. It is also known that when the reticuloendothelial system is blockaded by cortisone, adherence of the foreign bodies to the cell membrane of phagocytes, and initial step of phagocytic mechanism, and absorption of foreign body into the cytoplasm of phagocytes are considerably disturbed. An investigation was undertaken to study the phagocytic activity of the omental milk spots by light and electron microscopy. Sixteen albino rats, maintained on a stock diet, weighing 200.0gm. average, were divided into 3 experimental groups. Group 1. Control group. No intraperitooneal injection of india ink given. a. Two rats, untreated. b. 2 rats: A dose of 25 ㎎ of cortisone acetate was given intramuscularly for 6 consecutive days. Group 2. 6 rats: A single dose of 6.0㎖ of 2% india ink in normal saline was given once a day, intraperitioneally, for 3 consecutive days. Group 3. 6 rats: A dose of 25 ㎎of cortisone acetate was given intramuscularly, once a day, for 6 consecutive days. Starting on the 4th day, a 6.0㎖ of 2% india ink in normal saline, once a day, wa administered intraperitoneally, for 3 days. Each of the experimental rats were sacrificed 24 hours after the last treatment of india ink preparation from the groups 2 and 3. The control group was sacrificed simillarly. Then the greater omentum was extirpated and inspected for india ink pigmentation of the milk spots, followed by both light and electron microscopic examinations. The results were as follows: 1. Light microscopic observations: In the experimental group of rats treated with 25 ㎎ doses of cortisone acetate with a resulant reticuloendothelial system blockade followed by an intraperitioneal india ink injection (group 3), the degree of carbon particle phagocytic activity of omental milk spots was greatly diminished over the group of rats treated with india ink only (group 2). 2. Electron microscopic observations: The number of phagosomes in the cytoplasms of the phagocytes of the milk spots of the greater omentum was increased substantially in the group of rate treated with india ink only (group 2). In this group, a large quantity of carbon particles were found to be contained in the phagosomes. Although there was an increased number of phagosomes bearing carbon particles in the group of rats treated with 25㎎ doses cortisone acetate followed by india ink injection (group 3), the number of phagosomes in this group was less than in the group of rats treated with india ink alone (group 2). A considerable quantity of carbon particles were also found outside the cytoplasms of phagocytes for group 3. It can be concluded, therefor: The phagocytic activity of omental milk spots was greatly decimated but not completely inbibited when the reticuloendothelial system was blockaded by large quantity of cortisone administration.

      • 계측용 포터블 ESPI장치에 의한 강구조물의 결함 및 진동해석에 관한 연구

        김경석,정현철,최지은,정운관,김홍건 조선대학교 생산기술연구소 1999 生産技術硏究 Vol.21 No.2

        평판의 진동모드와 진동수의 실험적 해석을 비접촉 광학적 방법인 ESPI법을 이용하여 상세히 기술하였다. ESPI를 이용하여 진동모드와 진동수를 측정하기 위해 두 개의 다른 재료 로 된 시험편을 준비하고 세장비의 변화에 따라 두 개의 다른 가진점을 택해 가진 하였다. 측정된 결과는 유한요소해석(FEA) 및 Warburton이 제안한 이론해석과 정성적으로 비교하였다. 실험적 결과는 이론해석 결과는 물론 FEA 결과와도 잘 일치함을 알수 있었다. 결과적으로 ESPI 법이 진동모드와 진동수의 고정도 해석에 이용할 수 있음을 확인하였다.

      • KCI등재

        야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

        조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

        Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

      • KCI등재
      • SCOPUSKCI등재

        대학생들의 생활습관과 혈청 항산화비타민 및 지질상태의 관련성에 관한 연구

        권정숙(Chong-Suk Kwan),한은화(Eun-Hwa Han),윤수홍(Soo-Hong Yoon),장현숙(Hyun-Suk Jang) 한국식품영양과학회 1999 한국식품영양과학회지 Vol.28 No.1

        우리나라 일부지역 대학생들의 생활습관 즉 흡연량, 음주습관, 운동정도, 식습관 등과 영양소 섭취량을 알아보고 이들과 혈청 지질 및 항산화비타민 사이의 관련성을 조사한 결과는 다음과 같다. 조사대상자의 일반적인 특징은 남학생의 경우 나이가 20.75±2.14세, 신장과 체중이 173.04±5.30㎝, 66.96±9.4㎏이고, 여학생의 경우 19.16±0.01세, 161.04±4.77㎝, 53.57±5.20㎏이었다. 남녀대학생의 혈청 TC는 각각 158.60±32.66㎎/dl, 177.31±33.82㎎/dl이고, LDL-C은 86.38±25.97㎎/dl, 109.02±31.02㎎/dl, HDL-C은 45.97±10.66㎎/dl, 49.34±12.42㎎/dl이며, TG는 131.20±22.54㎎/dl, 91.70±38.56㎎/dl이었다. 동맥경화증의 위험지수인 AI는 남녀 각각 2.63±1.20, 2.75±1.12로 조사되었다. 혈청 중 항산화비타민의 수준은 남학생의 경우, 비타민 A, E 및 C가 각각 42.55±12.26㎍/dl, 1.11±0.38㎎/dl, 164.66±65.01㎍/dl, 여학생은 31.40±9.77㎍/dl, 1.15±0.29㎎/dl, 220.06±80.11㎍/dl였으며, Vt. E/TC(%)는 남녀 각각 0.70±0.18, 0.66±0.18이고, Vt. E/TG(%)는 남학생 1.17±0.56, 여학생 1.52±0.88로 나타났다. 흡연에 대한 혈청 지질 및 항산화비타민의 수준은 남학생의 경우 유의적인 차이가 나타나지 않았고, 여학생은 모두 비흡연자로 조사되었다. 음주에 대한조사에서 남학생의 경우 음주량이 많아질수록 혈청 비타민 C 수준이 유의적으로 감소하였으며 (p=0.038), 유의적이지는 않으나 TC, LDL-C 및 TG의 수준은 증가하는 경향이었고, 여학생의 경우 HDL-C이 유의적(p=0.007)으로 증가하다가 감소하는 경향이 나타났다. 남녀 모두 stress가 심할수록 HDL-C은 낮아지고 AI는 높아지는 경향을 보였다. 식습관은 남녀 모두 전반적으로 나쁜 것으로 나타났고, 식습관이 나쁠수록 혈청 TC와 LDL-C이 높으며, 항산화비타민 상태도 나쁜 경향을 보였으나 유의성은 없었다. This study was undertaken to investigate the relationship between the life style and the nutritional status of serum antioxidant vitamins and lipids in university male and female students. 48 male and 49 female students attending Andong university, aged between 18 and 25 years, were selected. Questions about the life styles including dietary intakes, food habits, smoking, drinking alcohol, exercise, stress were answered. And serum levels of antioxidant vitamins and lipids were determined. Average serum levels of total cholesterol, LDL-C, HDL-C, and triglyceride in male and female subjects were 158.6±32.7, 177.3±33.8; 86.4±26.0, 109.0±31.2; 46.0±10.7, 49.9±12.4; 131.2±22.5, 91.7±38.6㎎/dl respectively. Average serum levels of antioxidant vitamin A, E and C in male and female subjects were 42.6±12.3, 31.4±9.8㎍/dl, 1.11±0.38, 1.15±0.29㎎/dl and 164.66±65.01, 220.06±80.11㎍/dl respectively. There was no significant difference between smoking habits and either serum lipids or antioxidant vitamins level. The serum vitamin C level of drinkers was significantly lower(p=0.038), but serum lipids(total cholesterol, LDL-C, and triglyceride) were higher than non-alcoholic subjects. The subjects with severe stress had lower in HDL-C and higher in atherogenic index than others. This result indicates that oxidative stress may be increased in stressful environment from undesirable life styles and influence the status of serum lipid and antioxidant vitamins.

      • SCISCIESCOPUSKCI등재

        Prognostic Factors for Recurrence and Progression in Korean Non-Muscle-Invasive Bladder Cancer Patients: A Retrospective, Multi-Institutional Study

        Kim, Hyung Suk,Ku, Ja Hyeon,Kim, Se Joong,Hong, Sung Joon,Hong, Sung Hoo,Kim, Hong Sup,Kwon, Tae Gyun,Cho, Jin Seon,Jeon, Seong Soo,Joo, Kwan Joong,Ahn, Han Jong,Park, Hong Seok,Seong, Do Hwan,Kwon, D Yonsei University College of Medicine 2016 Yonsei medical journal Vol.57 No.4

        <P><B>Purpose</B></P><P>To identify the prognostic factors related to tumor recurrence and progression in Korean patients with non-muscle-invasive bladder cancer (NMIBC).</P><P><B>Materials and Methods</B></P><P>Data were collected and analyzed for 2412 NMIBC patients from 15 centers who were initially diagnosed after transurethral resection of bladder tumor (TURBT) from January 2006 to December 2010. Using univariable and multivariable Cox proportional hazards models, the prognostic value of each variable was evaluated for the time to first recurrence and progression.</P><P><B>Results</B></P><P>With a median follow-up duration of 37 months, 866 patients (35.9%) experienced recurrence, and 137 (5.7%) experienced progression. Patients with recurrence had a median time to the first recurrence of 10 months. Multivariable analysis conducted in all patients revealed that preoperative positive urine cytology (PUC) was independently associated with worse recurrence-free survival [RFS; hazard ratio (HR) 1.56; <I>p</I><0.001], and progression-free survival (PFS; HR 1.56; <I>p</I>=0.037). In particular, on multivariable analysis conducted for the high-risk group (T1 tumor/high-grade Ta tumor/carcinoma <I>in situ</I>), preoperative PUC was an independent predictor of worse RFS (HR 1.73; <I>p</I><0.001) and PFS (HR 1.96; <I>p</I>=0.006). On multivariable analysis in patients with T1 high-grade (T1HG) cancer (n=684), better RFS (HR 0.75; <I>p</I>=0.033) and PFS (HR 0.33; <I>p</I><0.001) were observed in association with the administration of intravesical Bacillus Calmette-Guérin (BCG) induction therapy.</P><P><B>Conclusion</B></P><P>A preoperative PUC result may adversely affect RFS and PFS, particularly in high-risk NMIBC patients. Of particular note, intravesical BCG induction therapy should be administered as an adjunct to TURBT in order to improve RFS and PFS in patients with T1HG cancer.</P>

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