초음파현미경에서 V(z)곡선의 시뮬레이션과 열화평가에의 응용

조동수,박익근,임재생,안형근,심우식,김홍준 한국비파괴검사학회 2004 학술대회 논문집 Vol.- No.-

중소도시 가로경관의 선호특성 분석에 관한 연구 : 가로공간과 가로변건축물의 계획요소를 중심으로 Focused on the planning elements of roadside space and building

조홍정,박춘근 대한건축학회 2004 대한건축학회논문집 Vol.20 No.9

This study is about find ing out the preferred urban road landscape and suggest a way to plan it the result summarized as follows First, local characters must be regarded during urban development and expansion Especially, undeveloped areas with high potential or open space need systematic management Second, the unvarying shape of roof like the flat-type roof and simple repetition of horizontal and vertical openings are the most serious problems concerning the building shapes Third, design elements concerning the planing of street area are space structure, street type and building shape, what pedestrians considered most important was street type, next was building shape and last was space structure Finally, the trends of road landscape preference is that once the space had been obtained roadside trees and a green environment was properly planted and also continuous building lines were preferred the most by pedestrians

안면비대칭 정도에 따른 정모 두부방사선사진관 3차원영상의 비교 연구

조홍규,김경근,황현식 전남대학교 치과대학 2001 구강과학 Vol.13 No.2

The purpose of this study was to find out the problems of P ­ A cephalometric measurements used in the facial asymmetry analysis and to show the necessity of using three ­ dimensional morphometry. Steel ball (1.2㎜ in diameter) were attached in twenty seven landmarks of symmetrical artificial human skull, and eighty seven different asymmetrical artificial human skulls were formed by enlarging gradually remus height, mandibular body length, and gonial angle of the hemiface. From the P ­ A cephalometry and three ­ dimensional morphometry of each skull types, three linear measurements (representing ramus height, mandibular body length, mandibular length) and two angle measurements (representing gonial angle, menton deviation) and two area measurements (representing mandibular area, lower facial area) were acquired and made into asymmetry index. Menton deviation itself was used as asymmetry index while left ­ right differences were used in the other measurements. These asymmetry index were compared with each other to show the different aspect of the seven asymmetry index according to the degree of actual facial asymmetry. Through the statistical analysis, following results were obtained. 1. When actual ramus height difference becomes large, menton deviation and lower facial area asymmetry index of P ­ A cephalometry were reduced significantly more than those of three ­ dimensional morphometry (p<0.001). 2. When actual mandibular body length difference becomes large, ramus height, lower facial area asymmetry index of P ­ A cephalometry were reduced significantly (p<0.001) while mandibular body length, mandibular length, gonial angle, and mandibular area asymmetry index of P ­ A cephalomentry were magnified significantly more than those of three ­ dimensional morphometry (p<0.01). 3. When actual gonial angle difference becomes large, gonial angle asymmetry index of P ­ A cephalometry was reduced significantly (p<0.001) while lower facial area, mandibular body length, and mandibular area asymmetry index were magnified significantly more than those of three ­ dimensional morphometry (p<0.01). 4. When the correlation between actual ramus height difference and seven asymmetry index of P ­ A cephalometry and three ­ dimensional morphometry was analysed, no difference between P ­ A cephalometry and three ­ dimensional morphometry was found (p<0.01). 5. When the correlation between actual mandibular body length difference and seven asymmetry index of P ­ A cephalometry and three ­ dimensional morphometry was analysed, significance was found in mandibular body length, mandibular length, menton deviation, mandibular area, and lower facial area (p<0.001) while significance was found only in gonial angle of three ­ dimensional morphometry (p<0.01). 6. When the correlation between actual gonial angle difference and seven asymmetry index of P ­ A cephalometry and three ­ dimensional morphometry was analysed, significance was found in gonial angle (p<0.001) while significance was found only in lower facial area of three ­ dimensional morphometry (p<0.01). The above results suggest that three ­ dimensional morphometry show to be necessary for the accurate facial asymmetry analysis.

뇌졸중 환자의 경상운동이 상지기능에 미치는 영향

조영남,김홍근,권혁철 대구대학교 특수교육재활과학연구소 2008 再活科學硏究 Vol.26 No.2

경상운동은 다른 쪽의 신체에서 일어나는 의도된 움직임의 경상 반전으로 발생하는 한 쪽 신체의 무의식적인 운동이다. 본 연구는 뇌졸중으로 인한 편마비 환자에게서 나타나는 경상운동이 상지기능에 미치는 영향에 대해 알아보고자 하였다. 65명의 뇌졸중 환자를 대상으로 연구한 결과, 경상운동이 나타나지 않은 환자군의 상지기능은 경상운동이 나타난 환자군의 상지기능과 통계학적으로 유의한 차이를 보였으며, 경상운동이 나타난 환자군에 비해 상지기능이 좋은 것으로 나타났다. 또한, 경상운동이 나타나지 않은 환자군과 경상운동이 경한 환자군, 경상운동이 중한 환자군의 상지기능을 비교한 결과 경사운동이 적게 나타날수록 상지기능이 좋은 것으로 나타났다. 연구의 결과를 종합하여 볼 때, 뇌졸중으로 인한 편마비 환자에게서 나타나는 경상운동은 상지기능을 감소시키는 요인 될 수 있는 것으로 나타났다. The purpose of this study was to compare upper extremity's motor function according to the mirror movements in hemiparetic patients with stroke. Mirror movements are involuntary movements in one side of the body that occur as mirror reversals of the intended movement on the other side of the body. The subjects of the study were 65 stroke patients who were admitted from May, 2004 to April, 2005 in the Y University medical center. This study used the Manual Function Test(MFT) and the Purdue pegboard test to evaluate upper extremity‘s motor function. The severity of mirror movements were assessed according to the criteria of Woods and Teuber. The results of the study was as follow; First, The upper extremity‘s motor function in hemiparetic patients without mirror movements was significantly different in hemiparetic patients with mirror movements(p< .05). Second, The upper extremity's motor function in hemiparetic patients with mild mirror movements was significantly different in hemiparetic patients with severe mirror movements(p< .05). The result showed that the mirror movements in hemiparetic stroke patients are correlated with upper extremity's motor function and the severity of mirror movements affected upper extremity's motor function. 경상운동은 다른 쪽의 신체에서 일어나는 의도된 움직임의 경상 반전으로 발생하는 한 쪽 신체의 무의식적인 운동이다. 본 연구는 뇌졸중으로 인한 편마비 환자에게서 나타나는 경상운동이 상지기능에 미치는 영향에 대해 알아보고자 하였다. 65명의 뇌졸중 환자를 대상으로 연구한 결과, 경상운동이 나타나지 않은 환자군의 상지기능은 경상운동이 나타난 환자군의 상지기능과 통계학적으로 유의한 차이를 보였으며, 경상운동이 나타난 환자군에 비해 상지기능이 좋은 것으로 나타났다. 또한, 경상운동이 나타나지 않은 환자군과 경상운동이 경한 환자군, 경상운동이 중한 환자군의 상지기능을 비교한 결과 경사운동이 적게 나타날수록 상지기능이 좋은 것으로 나타났다. 연구의 결과를 종합하여 볼 때, 뇌졸중으로 인한 편마비 환자에게서 나타나는 경상운동은 상지기능을 감소시키는 요인 될 수 있는 것으로 나타났다. The purpose of this study was to compare upper extremity's motor function according to the mirror movements in hemiparetic patients with stroke. Mirror movements are involuntary movements in one side of the body that occur as mirror reversals of the intended movement on the other side of the body. The subjects of the study were 65 stroke patients who were admitted from May, 2004 to April, 2005 in the Y University medical center. This study used the Manual Function Test(MFT) and the Purdue pegboard test to evaluate upper extremity‘s motor function. The severity of mirror movements were assessed according to the criteria of Woods and Teuber. The results of the study was as follow; First, The upper extremity‘s motor function in hemiparetic patients without mirror movements was significantly different in hemiparetic patients with mirror movements(p< .05). Second, The upper extremity's motor function in hemiparetic patients with mild mirror movements was significantly different in hemiparetic patients with severe mirror movements(p< .05). The result showed that the mirror movements in hemiparetic stroke patients are correlated with upper extremity's motor function and the severity of mirror movements affected upper extremity's motor function.

전북 평야 수도작 농가의 담수직파 기술개발 방향 및 경제성 분석

조홍기,신용규,박정근 全北大學校 1995 論文集 Vol.39 No.-

New technology plays a role of stimulator in releasing the constraints on growth imposed by resource endowment in any society. In an economy with high population pressures and limited land, increases in output depend on the development of land-saving technology, that can release the constraints imposed by the inelastic supply of land. The development of fertilizer-responsive crop varieties, which is identified as biological technology, can essentially be a new technology designed to facilitate the substitution of fertilizer (or pesticides) for scare land and to raise yield per Ha. In an economy characterized by a relative scarcity of labour, the improvement of agricultural machinery that can save labour and raise labour productivity may reduce the problem of labour shortage. The constraints imposed by an inelastic supply of labour may be offset by advances in so called mechanical technology. The Technology of Direct-Seeding in paddy rice cultivation (TDS), which has rapidly diffused among individual farmers in recent years, may be the same scale-neutral technology as Tong-il HYVs. It may be said that the TDS has been designed to solve the problem that results from the bottlenecks of labour shortage and high labour cost. It is also assumed that the TDS may be the technical innovation that is induced by changes in factor endowments in market economy while Tong-il HYVs may be the technological development that is leaded by the government's incentives to attain self-sufficiency of staple food. In the area of agricultural policy, the study has a crucial role in establishing a desirable direction for agricultural reconstruction-policy for improving agricultural infrastructure and in providing information for the scientific technology-policy for attaining more efficient resource allocation in agricultural research.

한국인 주의력결핍 과잉행동장애 아동에서 도파민 D4 수용체 유전자의 Variable Number of Tandem Repeats (VNTR) 다형성과 Methyphenidate 치료 반응간의 연관성

천근아,김붕년,조수철,김재원,황준원,신민섭,홍강의 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : In the present study, we investigate the association between homozygosity of the 4-repeat allele (4/4) at the DRD4 and the response to the treatment with MPH in Korean children with ADHD. Methods : The present study included 71 children with ADHD (8.231.78 years) from two children's psychiatric clinics in South Korea. All drug-naive children with ADHD were treated with MPH for about 8 weeks. The subjects who showed improvement of over 50% compared with the baseline ARS score after 8 weeks of treatment were termed as the 'good response' group. The subjects who showed an improvement of less than 50% were considered as the 'poor response' group. After genotyping for DRD4 were performed, we investigated correlation between homozygosity for 4-repeat allele at DRD4 and the response to MPH treatment. Results : We found that while 79.5% (31/39) of the subjects with homozygosity of 4-repeat allele at DRD4 showed good response to MPH treatment, 68.8% (22/32) of the subjects without homozygosity of 4-repeat allele at DRD4 showed poor response to MPH treatment according to ARS scores assessed by their parents (χ²= 16.762, df= 1, p<0.01). We also found that while 61.5% (24/39) of the subjects with homozygosity of 4-repeat allele at DRD4 showed good response to MPH treatment, 87.5% (28/32) of the subjects without homozygosity of the 4-repeat allele at DRD4 showed poor response to MPH treatment according to ARS scores assessed by their teachers (χ²= 17.698, df= 1, P<0.01). Conclusion : Our findings support an association between the homozygosity of 4-repeat allele and a good response to MPH in ADHD of Koreans.

末梢神經腫瘍에서 GFAP의 免疫組織化學的 表現에 關한 硏究

기근홍,조국형,범진선 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.2

Glial fibrillary acidic protein (GFAP) is one of the intermediate filament proteins, It is avaUable for identification of tumors glial cell origin in central nervous system. The specialized cells of the peripheral nervous system could express GFAP. The materials for our study consisted of 25 neurofibroma and 15 neurilemmoma, that resected for diagnosis or definite treatment at Chosun University Hospital from January, 1989 to December, 1991. All cases were performed of immunohistochemical stain for GFAP, vimentin and S-100 protein by ABC method. Immunoreactivity was evaluated and compared with the reactivity of GFAP, vimentin and S-100 protein. All cases of neurofibroma and neurilemmoma was positively stained in the neoplastic cells to the vimentin and S-100 protein. GFAP were positively stained in 10 of 25 neurofibroma (40%) and 11 of 15 neurilemmoma (73%). In the neurilemmoma, the positive cells were found primarily in cellular area, rarely in verocay bodies. Dermal neurofibromas were negative for GFAP, except of deeply located plexiform neurofibromas. Positive tumor cells were usually bipolar and spindle-shaped. The GFAP positive tumor cells were appeared around in hyalinized vessels in many cases.

급성 복통을 주소로 진단된 자발성 양측 부신 출혈에 의한 부신피질부전

조아름,홍주영,김동호,박민지,권미혜,박근용,원희관,임동미 이화여자대학교 의과학연구소 2014 EMJ (Ewha medical journal) Vol.37 No.S

Thomas Addison은 1855년 발표된 그의 논문에 일차성 부신피질부전에 의하여 발생한 근력 약화, 피로, 식욕부진, 복통, 체중감소, 색소침착 등에 대하여 처음으로 기술하였다[1,2]. 부신피질부전은 부신피질의 파괴에 의해 발생하는 당질 코르티코이드 결핍과 관련된 일차성과 뇌하수체에서 혈청 부신피질자극 호르몬(adrenocorticotropic hormone, ACTH)의 분비장애에 의해 발생하는 이차성으로 구분할 수 있다. 일차성과 이차성의 중요한 차이는 무기질 코르티코이드의 결핍이 일차성에는 있고 이차성에 는 없다는 점이다. 일차성 부신피질부전의 원인으로 이전에는 결핵에 의한 양측 부신 파괴가 가장 흔한 원인이었으나, 결핵 진단율 및 치료약제 보급률이 좋아진 20세기 후반부터는 감소 추세를 보이고 있으며, 선진국에서는 자가면역성 부신염에 의한 일차성 부신피질 부전이 80~90%로 가장 흔한 것으로 보고되었다[3]. 이외에 다른 감염성 질환, 전이성 암, 림프종, 부신출혈 또는 경색, 약물 등의 원인을 들 수 있다. 일차성 부신피질부전의 임상 증상과 징후로는 전신무력감, 식욕부진, 피로감, 체중감소, 과다한 색소침착, 오심, 복통, 기립성 저혈압, 저혈당, 전해질 장애 등이 올 수 있고, 심하면 탈수, 저혈압, 의식장애 및 쇼크가 동반될 수 있다. 일차성 부신피질부전은 본 증례와 같이 드물게 양측 부신 출혈성 경색으로 인해 발생되는 경우가 보고되었는데, 위험인자로는 항응고제 또는 헤파린 투여, 혈전성 질환, 항인지질 증후군과 같은 과응고 상태, 물리적 외상, 감염, 심한 스트레스와 관련되어 발생할 수 있으며 드물게 임신, 부신 종양, 쇼크 등이 원인이 되고 있다[4,5]. 그러나 본 증례와 같이 원인 없이 발생한 자발성 출혈에 의한 부신피질부전의 보고는 매우 드물다. 양측 부신 출혈의 임상 증상과 징후로는 저혈압, 쇼크, 복부, 등, 옆구리, 흉부의 통증, 발열, 의식저하, 복부 강직, 반발 압통 등이 있다[6]. 적절한 치료를 시행하지 않으면 쇼크가 진행하여 혼수와 사망에 이를 수 있어 정확하고 빠른 진단과 치료가 필요하다. 환자가 생존한다면 부신 기능은 드물게 수개월 후 정상으로 회복될 수 있다[7]. 저자들은 상복부 통증을 주소로 내원한 환자에서 매우 드물게 원인 없이 발생한 자발성 양측 부신 출혈에 의한 급성 부신피질부전 1예를 경험하였기에 보고하는 바이다.

시각장애자용 문자인지 장치에 관한 연구

허웅,조병서,김진곤,함광근,민홍기 明知大學校 産業技術硏究所 1994 産業技術硏究所論文集 Vol.13 No.-

In this paper, we implemented the hangeul tactile recognition system for the Blind. The system is consist of hardware part and software part.The hardware part is consist of a scanner interface image processing system, a electro tactile output device inter and auser interface. The software system consist of pattern learning routine,image processing and character pattern output routine, file management and operation window routine. The 16 by 16 of return electrode is driven by a electro-tacttile device. The recognition experimention distinguished learning beforefrom learning after,after learning the recognition rate is higher than learning before. As a results of experimentation before and after learning,the later is superior to the former. Therefore,if learning is increased, we can take higher recognition rate.

류마티스성 승모판 협착증의 치료를 위한 경피적 승모판 성형술의 치료성적

김성은,조흥근,박성훈,박시훈 梨花女子大學校 醫科大學 醫科學硏究所 1999 EMJ (Ewha medical journal) Vol.22 No.4

연구목적 : 류마티스성 승모판 협착증에 대한 유용한 치료법인 경피적 승모판 성형술의 본원의 단기 치료 성적을 알아보고자 하였다. 방법: 1993년 10월에서 1999년 4월까지의 이대목동병원에 내원한 류마티스성 승모판 협착증 환자 21명에서 투시조명 하에 경피적 승모판 성형술을 시행하였다. 시술전에 경흥부심초음파와 경식도초음파가 시행되었고, 시술후에는 경흉부초음파를 사용하여 혈역학적, 임상학적 변화를 비교하였다. 연구대상의 거의 모두가 NYHA class Ⅱ에 속했고, 5명이 심방세동을 가지고 있었으며, 모두 심초음파점수가 8이하였다. 좌심방에 혈전이 있는 경우로 혈전을 용해시킨 후 시술한 경우가 2예였다. 결과 : 경피적 승모판 성형술 이후의 평균 승모판구면적은 시술전의 1.16±0.36㎠에서 2.06±0.33㎠로 증가되었다. 경승모판 이완기 평균 압력차는 시술전 11.60±5.54mmHg에서 시술 후 4.93±2.53mmHg(p<0.001). 좌심방 크기는 46.41±14.66mm에서 42.03±15.01mm로(p=0.042), 그리고 심박출량은 4.21±1.25L/min에서 6.88±9.57L/min로(p<0.0001) 의미있는 호전을 보였다. 3도 이상의 심한 승모관폐쇄부전이나 심각한 시술후 합병증은 없었다. 결론 : 본원에서 약 6년간 시행된 경피적 승모판 성형술는 그 사례가 적고 시술전 예상되는 난이도 면에서 특이한 것은 없었지만, 시술후 합병증이 거의 발견되지 않았으며 혈역학적 측정상에서도 성공적인 시술을 보여주었다. 승모판구면적에 따른 시술후 단기내 호전의 정도는 거의 예측할 수 없었으나, 심초음파점수는 모두가 8점이하로 높은 성공율의 조건을 제공하였다. Objective : Percutaneous mitral valvuloplasty(PMV) became a treatment modality or mitral stenosis because of its low morbidity, short hospital stay, and low cost. We reviewed clinical and hemodynamic results after PMV for the patients with mitral stenosis in Ewha Womans University Mokdong hospital. Methods : We compared the results of echocardiographic, hemodynamic, and clinical parameters before and after PMV. PMV was performed under fluoroscopic guidance in 21 patients(M:4, F:17, mean age 43±12 years) with mitral stenosis from October 1993 to April 1999. Transesophageal echocardiography(TEE) and Transthoracic echocardiography(TTE) were performed for the evaluation of mitral valve, chamber size, and the presence of left atrial thrombus before procedures. TIE was also used for follow-up evaluation. On presentation, all patients showed at least NYHA class Ⅱ. Five patients had atrial fibrillation. Two patients with thrombus in the left atrium were included to study group after thrombolytic treatment with coumadin. Echo-score of our patients was not greater than 8. Results : Mean mitral valve area(MVA) by 2 dimensional or Doppler echocardiography was increased from 1.16±0.36㎠ before PMV to 2.06±0.33㎠ after PMV. There were marked improvements in transmitral gradients(11.60±5.54mmHg before PMV vs 4.93±2.53mmHg after PMV, p<0.001), left atrial dimension(46.41±14.66mm vs 42.03±15.01mm, p=0.042), and cardiac output(4.21±1.25L/min vs 6.88±9.57L/min, p<0.0001) following PMV, Severe(≥GⅢ) mitral insufficiency or severe postprocedural complications were not noted. This suggested that all procedure was successful. Conclusion : The Procedural success rate of PMV in Ewha Womans University Mokdong hospital was 100%. Low echo score of our patients might explain this high procedural success rate. Long-term-follow-up is warranted in the near future.