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( Osamu Tanifuji ),( Tomoharu Mochizuki ),( Hiroshi Yamagiwa ),( Takashi Sato ),( Satoshi Watanabe ),( Hiroki Hijikata ),( Hiroyuki Kawashima ) 대한슬관절학회 2021 대한슬관절학회지 Vol.33 No.-
Purpose: The purpose of this study was to evaluate the post-operative three-dimensional (3D) femoral and tibial component positions in total knee arthroplasty (TKA) by the same co-ordinates’ system as for pre-operative planning and to compare it with a two-dimensional (2D) evaluation. Materials and methods: Sixty-five primary TKAs due to osteoarthritis were included. A computed tomography (CT) scan of the femur and tibia was obtained and pre-operative 3D planning was performed. Then, 3D and 2D postoperative evaluations of the component positions were performed. KneeCAS (LEXI, Inc., Tokyo, Japan), a lowerextremity alignment assessment system, was used for the 3D post-operative evaluation. Standard short-knee radiographs were used for the 2D post-operative evaluation. Differences between the pre-operative planning and post-operative coronal and sagittal alignment of components were investigated and compared with the results of the 3D and 2D evaluations. Results: According to the 3D evaluation, the difference between the pre-operative planning and actual postoperative sagittal alignment of the femoral component and the coronal and sagittal alignments of the tibial component were 2.6° ± 1.8°, 2.2° ± 1.8° and 3.2° ± 2.4°, respectively. Using the 2D evaluation, they were 1.9° ± 1.5°, 1.3° ± 1.2° and 1.8° ± 1.4°, making the difference in 3D evaluation significantly higher (p = 0.013, = 0.003 and < 0.001). For the sagittal alignment of the femoral component and the coronal and sagittal alignment of the tibial component, the outlier ( > ± 3°) ratio for the 3D evaluation was also significantly higher than that of the 2D evaluation (p < 0.001, = 0.009 and < 0.001). Conclusions: The difference between the pre-operative planning and post-operative component alignment in the 3D evaluation is significantly higher than that of the 2D, even if the same cases have been evaluated. Twodimensional evaluation may mask or underestimate the post-operative implant malposition. Three-dimensional evaluation using the same co-ordinates’ system as for pre-operative planning is necessary to accurately evaluate the post-operative component position.
Numata, Tomohiro,Murakami, Tatsuya,Kawashima, Fumiaki,Morone, Nobuhiro,Heuser, John E.,Takano, Yuta,Ohkubo, Kei,Fukuzumi, Shunichi,Mori, Yasuo,Imahori, Hiroshi American Chemical Society 2012 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY - Vol.134 No.14
<P>The control of ion transport across cell membranes by light is an attractive strategy that allows targeted, fast control of precisely defined events in the biological membrane, Here we report a novel general strategy for the control of membrane potential and ion transport by using charge-separation molecules and light. Delivery of charge-separation molecules to the plasma membrane of PC12 cells by a membranous nanocarrier and subsequent light irradiation led to depolarization of the membrane potential as well as inhibition of the potassium ion flow across the membrane. Photoregulation of the cell membrane potential and ion transport by using charge-separation molecules is highly promising for control of cell functions.</P>
Masaki Onoyama,Takeshi Tsuka,Tomohiro Imagawa,Tomohiro Osaki,Saburo Minami,Kazuo Azuma,Kazuhiko Kawashima,Hiroshi Ishi,Takahiro Takayama,Nobuhiko Ogawa,Yoshiharu Okamoto 대한수의학회 2014 JOURNAL OF VETERINARY SCIENCE Vol.15 No.1
Sixteen cases of malignant soft tissue sarcoma (STS; 10canines and six felines) were treated with a novel tripletherapy that combined photodynamic therapy, hyperthermiausing indocyanine green with a broadband light source, andlocal chemotherapy after surgical tumor resection. This tripletherapy was called photodynamic hyperthermal chemotherapy(PHCT). In all cases, the surgical margin was insufficient. Inone feline case, PHCT was performed without surgicalresection. PHCT was performed over an interval of 1 to 2 weeksand was repeated three to 21 times. No severe side effects,including severe skin burns, necrosis, or skin suture rupture,were observed in any of the animals. No disease recurrence wasobserved in seven out of 10 (70.0%) dogs and three out of six(50.0%) cats over the follow-up periods ranging from 238 to1901 days. These results suggest that PHCT decreases the riskof STS recurrence. PHCT should therefore be considered anadjuvant therapy for treating companion animals with STS inveterinary medicine.