前腕部 經穴 取穴에서 骨度分寸法과 一夫法의 比較 硏究

박히준,채윤병,차웅석,박종배,이혜정,이향숙,인창식,고형균,김수영,최일환,김강식,문정배,배기태,유경환,육근영,정병주,손인철,임사비나 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-

Background : The cun measurement System, an essential and convenient method in locating acupoints, has been widely used in the practice of acupuncture. However, traditional cun measurement has been criticized for its lack of reliability. Objectives : The purposes of this study are to determine if one cun measured by the directional methods have a consistency with that of proportional methods and to investigate which factors are related with these differences, especially in forearm. Methods : The distance between the elbow crease and the wrist crease of forearm was compared to a reference value of one cun obtained by the directional method. In this method, one cun is one third of the distance between index finger and Small finger of a subject, measured at proximal interphalangeal joint. In addition, to investigate the factors influencing the differences between these two methods, we measured the height and body weight and calculated body mass index (BMI). Finally we analyzed the factors correlated with these lengths by linear regression test. Results : The results showed that one cun obtained by the directional methods were significantly different from one cun by the proportional methods in forearm. It was demonstrated that the length acquired with the directional method was more correlated with body weight and body mass index, while the length obtained by the proportional method was more correlated with the height.

WHO 침구임상 지침서 개정을 위한 국제회의 보고

박히준,서정철,김세현,김상우,안경애,임사비나,김용석,최도영,강성길 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

The Working Group on the revision of Clinical Research Methodology for Acupuncture met in Seoul, Republic of Korea from 24 to 26 August 2005. The main objectives of the meeting were to review the regional publication guidelines for Clinical Research on Acupuncture, to make necessary revisions in the guidelines, to make recommendations on further collaboration and activities in the field of research on acupuncture, and to discuss scientific evidence-based approaches in the clinical research on acupuncture. Fourteen members from the eight Member States, one secretariat staff from the WHO Regional Office for the Western Pacific and ten observers from the Republic of Korea attended the meeting. The members presented their papers to review the current status of clinical research on acupuncture. The drafts of proposed revision to the previous guidelines for clinical research methodology on acupuncture were discussed extensively. The issues covered during the discussion included: the definition of the new terms; reorganization of clinical research design; revision and update of contents (e.g., control group); introduction of Institutional Review Board (IRB) on the section of ethical approval; additional outcomes including health-related quality of life (HRQOL), qualitative measures, etc. In the course of these discussions, the working group developed the revised guidelines for clinical research on acupuncture and made recommendations for promoting the dissemination of the revised guidelines.

實驗感染鼠癩에 있어서 數種藥劑의 發症抑制作用에 關하여

朴姬淑,金重明 慶北大學校 醫科大學 1972 慶北醫大誌 Vol.13 No.2

In order to study inhibitory effects of DDS, Ciba 1906, INHA and SM in experimentally infected murine leprosy, 102 mice were used: two mice were used for control 50 mice were inoculated subcutaneously at the right side of the lower abdomen and were designated as the group A, another 50 mice were inoculated mycobacteria subcutaneously at the right side of the back and designated as the group B. Each group A and B were divided into 5 subgroups for the control, DDS, Ciba 1906, INAH and SM and were adminstered with respective drug to each subgroup. Group A was observed by spreading method and group B observed by the leprom size. The results were as follows; A. Results of spreading method: 1) The mycobacteria inoculated were observed in the monocytes and polymorphonuclear cells as fine masses on the next day of inoculation. 2) In the control group, the mycobacteria in the monocyte on the 2nd week of inoculation were more elongated and increased in number. There were much increase in number of moncytes and decreas of polymorphonuclear cells. The above feature was more clearly observed on the 4th week of inoculation. The preparation of the spreading method was impossible because of formation of the leprom. 3) Only the INAH was to seem to be effective on the 2nd and 3rd week and the DDS, Ciba 1906 and SM show no inhibitory effect, B.Results of the leprom formation: 1) In the control group, on the 4th week 3 mice began to form leprom and on the 6th week it was formed in all of the mice and on the 8th grow to 18th week, it to maximum size. There was ulcer formation in 5 mice. 2) In the DDS group, on the 4th week the leprom was observed only in one mouse on the 6th week the leprom was found in all of them and reached the maximum size, on the 6th to 16th week. The ulcer was observed only in one mouse. 3) In the Ciba 1906, on the 2nd week the leprom was found only in one mouse, and on the 4th week in 7 mice, and on 6th week it was found in all mice, of the group and reached to maximum size on the 16th week. 4) In the INAH group, on the 4th week the leprom was observed in one mouse but it disappeared on the 6th week and appeared again on the 8th to 10th week and disappeared again on the 12th week and reappeared on the 18th week. In one other mouse, small leprom was found on the 14th week and durated to the 18th week, in other 2 mice the leprom was found on the 18th week. 5) In the SM group, on the 6th week leprom was observed in 2 mice, and on the 10th week it was found in all mice, and they were grown gradually to maximum size in the 18th week. 6) In inhibitory effect of INAH against the experimental murine leprosy was the strongest among the drugs tested.

장기투석을 받은 만성 신부전 환자에서 발생한 종양에 관한 고찰

황정화,이혜경,홍현숙,박재성,김대호,권귀향,최득린,황승덕,이희발 순천향의학연구소 1996 Journal of Soonchunhyang Medical Science Vol.2 No.2

The authors tried to evaluate tumor occurrence in long-term dialysis patients with chronic renal failure. Among 359 patients, 20 patients (about 5.6%) were diagnosed with malignancy during long-term dialysis from the period of 1983 to 1995 at our nephrology department. The ultrasonographic and computed tomographic findings including the clinical features of 20 patients that were retrospectively reviewed. The mean age of the patients was 53 (37-75)years old and the ratio of male to female was 9:1. Among the 20 cases, 7 cases of hepatoma (35%) were developed. Among them, urinary tract tumors such as renal and bladder cancer were developed in 4 (20%) and 2 (10%) of the cases. Other malignant tumors were lymphoma, stomach cancer, uterine cervical cancer, cholangiocarcinoma, lung cancer, meningioma, and acoustic neuroma one case of each (each of 5.3%). The most common tumor in patients with chronic renal failure, who were receiving long-term dialysis, was hepatoma and the second most common tumor was cancer of the urinary tract such as kidney and bladder.

귤응애 및 귤진딧물에 대한 Oligota yasumatsui K.와 몇가지 무당벌레 變種의 捕食能力

鄭熙浚,朴正德 제주대학교 1975 논문집 Vol.7 No.-

A study was conducted to evaluate the predatism of the staphilinid beetle(Oligota yasumatsui K.) and some lady beetles (five varieties of Harmonia axyrids, and Cocyinalla bruckii Mul.) on the citrus red mites (Panonychus citri McG.) and the citrus aphids(Toxoptera citricidus K.). The adults of the staphilinid beetle preyed on from 8.6 to 9.5 citrus red mites per day. The potentials of the lady beetle larvae (Harmonia axyridis var. 19-signata) to consume the aphids and the mites per day were 27.0 and 3.7 at the first stadium, 27.1 and 3.0 at the second stadium, 37.2 and 2.9 at the third stadium, and 46.0 and 2.9 at the fourth stadium, respectively. Regardless the varieties and/or species of the lady beetles, the adults much more consumed and prefered the aphids than mites. There was no specific relationships between predatism of the predators and temperature/humidity in this study.

Neuropeptide γ의 구조 및 생리활성

구희정,서정길,김은희,허민도,정준기,박장수,강신원,박남규 부산대학교 유전공학연구소 1997 분자생물학 연구보 Vol.13 No.-

생리활성을 지닌 신경펩타이드의 구조와 활성간의 관계를 규명하기 위하여 고상법으로 합성한 세종류의 neuropeptide γ(mammalian-,trout- 그리고 goldfish-neuropeptide γ)를 사용하여 연구하였다. Circular dichroism spectra에 의하면 mammalian-,trout- 와 goldfish-neuropeptide γ는 완충액 조건하에 모두 random한 구조를 나타내었다. 중성 및 산성 지질 존재 하에서, mammalian-과 trout- neuropeptide γ는 여전히 random한 구조를 취하였다. 그러나, goldfish-neuropeptide γ는 중성 및 산성지질하에서 부분적으로 α-helix구조를 나타내었다. 장관 수축활성에 있어서는 carp 장관, guinea-pig 회장 그리고 rat십이지장에 대하여 비교하였다. Carp에 대해서는 goldfish-neuropeptide γ= trout- neuropeptide γ>mammalian-neuropeptide γ순으로 활서이 나타났다. 그러나, guinea-pig 회장과 rat십이지장에 대해서 mammalian-neuropeptide γ는 어류 유래성 neuropeptide g들 보다 높은 수축활성을 나타내었다. 이러한 결과들은 neuropeptide γ들이 종-특이적인 활성을 나타낸다는 것을 제시한다. The relationship between structure and biological activity was studied on the three neuropeptides(mammalian-,trout- and goldfish-neuropeptide γ)that were syntheized by the solid-phase method. Circular dichroism spectra showed that mammalian-,trout- and goldfish-neuropeptide γadopted an undered structure in buffer solution. In the presence od neutral and acidic liposomes, mammalian-and trout- neuropeptide γ also took a random structure. However, goldfish-neuropeptide γ took an α-helical structure in acidic liposomes. The intestinal motility response was investigated with carp interstines, guinea-pig ileums and rat duodenums. In case of carp intestine, contractine activity was as follows:goldfish-neuropeptide γ= trout- neuropeptide γ> mammalian-neuropeptide γ. On the other hand, the contracile activity of mammalian-neuropeptide γ was more potent than trout- and goldfish-neuropeptide γ in the guinea-pig ileums and rat duodenums. these results suggest that neuropeptide γs showed the species-specific activity.

음식물쓰레기 관리의 최적화 방안 연구 : 창원, 마산, 진해시를 중심으로 Focused on Changwon, Masan, Jinhae City

이명희,박증석,김종오,백병천 國立 麗水大學校 環境問題硏究所 1998 環境硏究論文集 Vol.1 No.-

Limited landfill area and finance as well as a huge generation of waste, have called for systematic approaches towards potential cost savings. In this study, the management system of food wastes generated from the residential and commercial sources was considered in three citied; Changwon, Masan, and Jinhae city. Total thirteen alternatives were established and compared by applying the WRAP (Waste Resource Allocation Program). The following results were obtained: 1. While relatively small amounts were generated form the commercial sources such as cafeteria, restaurants, and market facilities, almost 80% of food wastes were generated from the residential sources. 2. Unit costs for food waste management in three cities were different according to their present situation, and the highest cost appeared in Jinhae city due to the most expensive construction of coastal landfill site. 3. Considering proper revenue, the whole conversion of food waste into animal feed was selected as the optimal alternative and represented 60% to 74% of management cost of the whole landfill alternative in all cities. Comparing the other alternatives, composting of food waste was more economical than the landfill alternative and the incineration was the most expensive alternative.

고카라트 Au-Zn-Pt 합금의 등온시효경화 거동

이희경,박영환,문희만,이정은,김형일 大韓齒科器材學會 2001 대한치과재료학회지 Vol.28 No.4

The isothermal age-hardening behavior of a high carat Au-Zn-Pt alloy was investigated by means of hardness test, X-ray diffraction study, microscopic observation and electron probe micro analysis. By the isothermal ageing of the solution-treated specimen at 300∼400℃, the hardness increased slowly at the initial stage of ageing and reached a maximum hardness values at 300∼400℃ was similar and suitable to use as the crown & bridge. By the isothermal ageing of the solution-treated specimen at 300∼400℃, three phases of the Au-rich α_1 phase with face-centered cubic structure,the Pt_3Zn a_2 phase with an ordered AuCu_(L1_2) type(f.c.c) and the Pt-rich a_3 phase with face-centered cubic structure were transformed into three phases of the α_1 phase, the α_3 phase and the PtZn β phase with an ordered AuCu I(L1_0) type. The hardening seemed to be attributed to the lattice strains of the matrix resulting from the transformation of the a_2 phase to the β phase. The overageing with softening was attributed to the coarsening of the nodule precipitates which seemed to be composed of the β phase and α_1 matrix.

Co/Mn/Br계 촉매상에서 p-자일렌 액상산화반응의 공정변수에 관한 연구

손용배,박경린,류태공,김정희,오인석,김영호,양현수 忠南大學校 産業技術硏究所 2001 산업기술연구논문집 Vol.16 No.2

Liquid phase oxidation of p-xylene using molecular oxygen has been carried out on the Co/Mn/Br-based catalyst system in acetic acid as a solvent. Process parameters(total pressure, partial pressure of oxygen and temperature) and kinetics of the reaction were studied as a basic study in the viewpoint for the development of new catalyst system and process. The total pressure above 20atm and the partial pressure of oxygen above 5atm were required to keep the reactant in the liquid phase and to overcome the mass transfer limitation of oxygen. The oxidation rate conversion were increased with increasing reaction temperature to the 100∼190℃ range. For a given initial concentration of p-xylene, the oxidation rate and the apparent activation energy were found to be of first-order and 4.24 ㎉/㏖, respectively. The effect of the third components added to the Co/Mn/Br catalyst was also studied. It was found that Ni is only a good additive that can promote the catalyst performance.

금연침에 대한 반응군과 비반응군의 유전자 다형성 차이 연구

윤동학,박히준,김승태,진수희,이수진,이혜정,임사비나 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-

Objectives : This study was designed to investigate the differences of effects in smoking cessation after acupuncture treatment and we hypothesized that the discrepancies might be caused by individual genetic differences. Methods : Acupuncture treatment was given to the subjects three times a week for the 231 healthy male Korean smokers without personal or familial history of psychiatric or neurological illness. We evaluated for differentiate responder and non-responder who showed more than 50% decrease in the cigarette consumption or the desire for smoking were regarded as responder, and less than 25% decrease in the cigarette consumption or the desire for smoking were regarded as non-responder, respectively. Allele and genotype frequencies of the Taq1 A polymorphism of dopamine D2 receptor (DRD2) gene were compared in 231male smokers. Chai-square analyses were performed to test for an interactive effect between the DRD2 Taq1 A allele. Results : The allele frequencies and genotype distributions of DRD2 gene among the smokers (n = 231) showed significant the differences in their genotype distributions. The responder and non-responder showed the difference in genotype distribution with a prevalence of A1 allele. A slightly positive association of DRD2 Taq1 A1 genotypes with smoking was observed. Conclusions : This experiment results indicate that the present of DRD2 allele genotype showing significant difference in the genotype distributions between responders and non-responders could be explained by the difference in the genetic effect of DRD2 A1 allele.