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체외충격파 쇄석술 시행 후 5년 뒤 발생한 요관 협착 및 농신장 1예
이현승,권균홍,조용건,김봉진,임창섭,김자영,허동,임학 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.4
A 40-years-old woman was admitted to this hospital with flank pain and high grade fever for 2 weeks. As a matter of her past history, extracorporeal shock wave lithotripsy (ESWL) was performed for treatment of renal stones 5 years ago. Her abdominal CT findings were hydronephrosis with pyonephrosis and renal stones. Antibiotics administered for 5 days had no effects on her symptom improvement. A right ureteral stricture was noticed by ultrasonography follow up. We inserted double J stent and continued antibiotics therapy for 10 days, and then her fever was disappeared and flank pain was improved. ESWL is one of the most important treatment of renal and ureteral stone. However, its complications should not be negligible including bleeding, pain, ureteral obstruction, infection and so on. Complications of ESWL can be divided into acute and chronic courses. When we treat pyelonephritis patient with past history of ESWL, possibility of ureteral stricture must also be considered. In this study we report a case of pyelonephritis caused by ureteral stricture, possibly as a chronic complication of ESWL performed 5 years earlier
김현우,허경회,이원진,허민석,이삼선,최순철 대한구강악안면방사선학회 2004 Imaging Science in Dentistry Vol.34 No.2
A case of sialadenitis is presented in a patient with painful swelling of the right mouth floor. The condition was caused by trauma on the right mouth floor during dental treatment, which had happened 15 days before admission. On aspiration, mucous secretion was found and ultrasonography showed obstruction of duct. Histopathological studies and surgical investigation established a definite diagnosis of obstructive sialadenitis caused by ductal laceration. As surgical treatment sialodochoplasty was selected. The case and relevant considerations are discussed.
정재현,이은지,이은주,황진원,송영진,최병진,김일환,김종윤,허민영,김동욱 인제대학교 2009 仁濟醫學 Vol.30 No.-
Neonatal lupus is a rare syndrome occurring In neonates with tranplacentally acquired maternal autoantibodies, In particular anti-SSA/Ro-SSB/Ra antibodies. Manifestations include congenital heart block, cutaneous lesions, thrombocytopenia, neutropenia, pulmonary or neurological disease and hepatitis. The non-cardiac manifestations resolve by 6 months of age, congenital heart block is irreversible. We experienced a case of neonatal lupus with congenital complete heart block in a newborn of asyptomatic mother with anti-SSA/Ro-SSB/Ra antibodies.
방사선사진에서의 골질과 임상적으로 평가한 골질 분류의 상관관계
김현우,허경회,박관수,김정화,이원진,허민석,이삼선,최순철 대한구강악안면방사선학회 2006 Imaging Science in Dentistry Vol.37 No.1
Purpose : To investigate the validity of digital image processing on panoramic radiographs in estimating bone quality before endosseous dental implant installation by correlating bone quality in radiographic images with clinical bone quality classification. Materials and Methods : An experienced surgeon assessed and classified bone quality for implant sites with tactile sensation at the time of implant placement. Including fractal dimension eighteen morphologic features of trabecular pattern were examined in each anatomical sites on panoramic radiographs. Finally bone quality of 67 implant sites were evaluated in 42 patients. Results : Pearson correlation analysis showed that three morphologic parameters had weak linear negative correlation with clinical bone quality classification showing correlation coefficients of -0.276, -0.280, and -0.289, respectively (p<0.05). And other three morphologic parameters had obvious linear negative correlation with clinical bone quality classification showing correlation coefficients of -0.346, -0.488, and -0.343 respectively (p<0.05). Fractal dimension also had a linear correlation with clinical bone quality classification with correlation coefficients -0.506 significantly (p<0.05). Conclusion : This study suggests that fractal and morphometric analysis using digital panoramic radiographs can be used to evaluate bone quality for implant recipient sites. (Korean J Oral Maxillofac Radiol 2006; 36 : 25-32)
파노라마방사선사진 지수와 임플란트 실패와의 관계에 관한 연구
조현정,이원진,허민석,안창현,이진구,이삼선,최순철 大韓口腔顎顔面 放射線學會 2004 Imaging Science in Dentistry Vol.34 No.1
Purpose : Several panoramic indices have been suggested to assess bone quality from the morphology and width of mandibular cortex on panoramic radiography. The purpose of this study was to compare dental implant failure group with control group in panoramic mandibular index (PMI), mandibular cortical index (MCI), and gonion index (GI) and to determine the effect of these panoramic indices on dental implant failure. Materials and Methods : A case-control study was designed. Test group (n = 42) consisted of the patients who had their implants extracted because of peri-implantitis. Control group (n = 139) consisted of the patients who retained their implants over one year without any pathologic changes and had been followed up periodically. They had dental implants installed in their mandibles without bone augmentation surgery from 1991 to 2001. The following measures were collected for each patients: 1) PMI, MCI, and GI were measured twice at one-week interval on preoperative panoramic views; and 2) age, sex, implant length, implant type, installed location, occluding dentition state, and complication were investigated from the chart record. Results : The PMI showed moderate level of repeatability. The intra-observer agreement of MCI and GI were good. There was statistically significant difference in PMI between two groups. There were significant different patterns of distribution of MCI and GI between two groups. Among the panoramic indices, PMI and MCI showed significant correlation with dental implant failure. Conclusion : Panoramic indices can be used as reference data in estimating bone quality of edentulous patients who are to have implants installed in their mandibles.
김현,허창욱,최진형 한국정신과학학회 2001 韓國精神科學學會誌 Vol.5 No.1
We evaluate the reliability of the emotional function BIOPIA Co., Ltd) through comparing the general utilized system MP100 (Biopac Systems Inc.). The 40 Hz re-sampled Photo-Plethysmo Graph (PPG) signals that acquired with the emotional function mouse are processed to determine heartbeat rate with peak detection algorithms (FIR band-pass filter, 6-point difference filter and threshold assign) and tested to how that rate are reliable compare to the MP100's one In addition, the correlation of the I Hz re -sampled Galvanic Skin Response(GSR) signals and the MP100s GSR signals are tested The evaluation tests are not carried out only In the stable humans condition but In stimulated conditions that caused Continuous Performance Test(CPT) and skipping. In this work, we evaluate the signals that acquired with emotional function mouse and the MP100 systems are strongly correlated over 0.97 in the case of PPG and over 0.98 in case of GSR Moreover, It should be available that Using the emotional function mouse as a utilized bio-Signal acquisition device.
Development of orthotopic patient-derived tumor xenograft models in endometrial cancer
( Hyun-jin Choi ),( Eun Jin Heo ),( Young Jae Cho ),( Ji Eun Hong ),( Hye-kyung Jeon ),( Doo-yi Oh ),( Yoon-la Choi ),( Sangyong Song ),( Jung-joo Choi ),( Yoo-young Lee ),( Chel Hun Choi ),( Tae-joon 대한산부인과학회 2016 대한산부인과학회 학술대회 Vol.102 No.-
목적: To evaluate orthotopic xenografting of endometrial cancer(EM Ca) in mice for development of novel translational research platform in endometrial cancer. 방법: Fresh surgical specimens were taken from patients with EM Ca after surgery at Department of Obstetrics and Gynecology, Samsung Medical Center, Seoul, Korea between December, 2011 to February, 2016. We successfully established PDXs by orthotopic and subrenal capsule implantation of patient’s EM Ca tissues into female BALB/C-nude mice. The subrenal capsule implatation method were that pieces of EM Ca specimens from patients were meticulosely grafted in the subrenal capsule. Mean while, estrogen preconditioning was done for orthotopic implatation by given a daily s.c injection of 0.1μg estradial for three days. After then, pieces of EM Ca specimens from patients were meticulosly grafted in the enlarged mice’s uterus. The H&E staining, short tandem repeat, array comparative genomic hybridization, human and mouse albumin test and cancer panel were conducted to verifythe histopathologic and genetic similarity between the PDXs and primary patient’s tissues. 결과: Orthotopic PDX engraftment rate were sucessful in 100% (3/3 cases). While, Successful rate of subrenal capsule implantation method was 55.6% (10/18 cases). In orthotopic PDXs, median duration of first generation of PDX develoment from implantation of patient’s tissues was 5.43month (range: 0.83-6.63 month). And, in subrenal capsule implantation PDXs, median duration of first generation was 5.05month (range : 4.17-9.33 month). Both methods were proved to preserve histopathologic and genetic silimarity between PDXs and the primary patient’s tissues. 결론: The PDXs for endometiral cancer with histopathologic and genetic stability can be efficiently developed by an orthotopic implantation method rather than a subrenal capsule implantation method. This method can a promising platform for conducting translational research and future precision medicine in endomerial cancer.