석면함유 슬레이트 지붕 물받이 퇴적물 중 석면 섬유 함유율

임지현,한솔민,김현석,신유민,박시은,허정윤,김민영,장봉기 순천향대학교 기초과학연구소 2022 순천향자연과학연구 논문집 Vol.28 No.1,2

This study attempted to determine the degree of asbestos release from the aging slate roof by comparing the asbestos content in the slate roof rain gutter with a colored steel plate (tin plate) over the slate roof. Four slate roof houses located in Haengmok-ri, Asan-si, Chungcheongnam-do, and one house constructed with a colored steel plate on the slate roof were selected to collect the sediment of the roof rain gutter. The asbestos fiber content was calculated by a point counting method using a polarization microscope after pretreatment with conversion treatment and hydrochloric acid treatment. The average asbestos content of the four slate roof rain gutter were 1.89%. However, asbestos was not detected in the Slate covering roof rain gutter, which were constructed on the slate roof. Asbestos fiber content was the highest at 2.89% in the slate roof rain gutter installed in 1976, followed by 2.44% in 1953. From the above results, it is necessary to minimize secondary damage as asbestos fibers released from slate roof houses to the surrounding atmosphere or leaked from slate roofs as rainwater may cause soil pollution and seriously affect residents' health. Although covering with colored steel plates (tin plates) has been shown to prevent the leakage of asbestos fibers to some extent, it is believed that a policy alternative to remove the slate roof as soon as possible is needed to solve the fundamental problem.

사무직 근로자의 수면의 질 및 직무스트레스와 우울과의 관련성

강미나,강수영,권수정,김현주,배재원,이보연,이예진,임의롬,정다영,조한솔 이화여자대학교 간호과학대학 2013 이화간호학회지 Vol.- No.47

Purpose: The purpose of this study was to understand the degree of depression, sleep quality, job stress and their association among office workers. Method: A self-administered questionnaire was distributed to 147 workers employed in 5 big enterprises, and 5 small and medium enterprises from October 21 to November 21, 2012. The questionnaires included socio-demographic and health-related characteristics, job-related characteristics, sleep quality, job stress (KOSS) and depression (CES-D). Result: Among all subjects, 23.1% was in the depression group (21 points and over in the CES-D score). Depressive level was positively correlated with job stress and quality of sleep. The adjusted odd ratio for the effects of sleep quality and job stress on depression significantly increased in the depression group compared to that of the normal group. Multiple regression analysis revealed that the following factors of influence had combined explanatory powers on depression: BMI, life satisfaction, quality of sleep, and job stress. Conclusion: The study revealed that complicated influences were exerted on the level of depression by variable factors, as well as socio-demographic characteristics, health-related characteristics, quality of sleep, and job stress. Specifically, the level of depression was influenced by the quality of sleep and job stress.

Germination Characteristics of Triploid Watermelon According to Mixing Ratio of Peat moss, Perlite and Vermiculite

Sol Ji Noh,Taek-Goo Jeong,Young-Sang Kim,Jong-Woo Han,Ik-Jei Kim,Tae-Il Kim 한국원예학회 2017 한국원예학회 학술발표요지 Vol.2017 No.5

Development of an Intelligent Gripper that Determines the Gripping Force According to the Weight of the Object

Han-Sol Kim,Gab-Soon Kim 한국정밀공학회 2023 International Journal of Precision Engineering and Vol.24 No.12

In this paper, we describe the development of a two-finger intelligent gripper that can determine the gripping force according to the weight of an object. The two-finger intelligent gripper features two 3-axis force sensors attached to the gripper plate. When this gripper grips an object, it simultaneously measures the weights Fx, Fy, and Fz in the x, y, and z directions of the object, calculates the weight of the object using this, and determines the force to grip the object according to the calculated weight. When the gripper safely grips an unknown object, it securely grips the object based on the determined gripping force. Structural analysis was performed using software to design the gripper, and a two-finger intelligent gripper was manufactured based on the design, and the manufactured two-finger intelligent gripper was subjected to a characteristic test. As a result, the manufactured two-finger intelligent gripper determined the gripping force according to the weight of the object, and was able to safely grip various objects using it.

Development of TILLING System for Screening of Target Gene in Pepper Mutation Population

Han Sol Kang,Yeong Deuk Jo,Sang Hoon Kim,Se Won Kim,Sun-Young Kim,Sang-woo Lee,Si-Yong Kang 한국원예학회 2017 한국원예학회 학술발표요지 Vol.2017 No.5

Robust Stabilization Condition for a Polynomial Fuzzy System with Parametric Uncertainties

Han Sol Kim,Jin Bae Park,Young Hoon Joo 제어로봇시스템학회 2012 제어로봇시스템학회 국제학술대회 논문집 Vol.2012 No.10

This paper concerns with the robust stabilization condition for the polynomial fuzzy system with parametric uncertainties. In the existing methods, nonlinear system with parametric uncertainties was modeled to the T-S fuzzy system. However, these methods has problem such as large number of the fuzzy rule. Therefore, this paper uses the polynomial fuzzy modeling method to manipulate the robust stabilization problem for the parameter uncertain nonlinear system. Furthermore, since new robust stabilization condition is derived from the polynomial Lyapunov function, so the condition is less conservative than previous robust stabilization condition. Finally, numerical example is given to show the validity of proposed method.

Intussusception and Jejunal Atresia Caused by an Ectopic Pancreas in a Newborn

Kim, Han-Sol,Lee, Sun-Young,Han, Song-Hee,Nam, So-Hyun,Jo, Chae-Ku,Kim, Myo-Jing The Korean Society of Neonatology 2021 Neonatal medicine Vol.28 No.2

Ectopic pancreas is defined as an abnormally located pancreatic tissue not sufficiently connected with the normal pancreas, which rarely occurs in neonates. To our knowledge, only a few cases of ectopic pancreas have been reported in newborns in South Korea. We report a case of ectopic pancreas as the cause of intussusception and jejunal atresia in a newborn. This clinical association is extremely rare, and this is the first report in South Korea.

Blood concentrations of lipopolysaccharide-binding protein, high-sensitivity C-reactive protein, tumor necrosis factor-α, and Interleukin-6 in relation to insulin resistance in young adolescents

Kim, Ki Eun,Heo, Ju Sun,Han, Sol,Kwon, Seul-Ki,Kim, Soo-Yeon,Kim, Jung Hyun,Baek, Kwang-Hyun,Sheen, Youn Ho Elsevier 2018 Clinica chimica acta Vol.486 No.-

<P><B>Abstract</B></P> <P><B>Background</B></P> <P>We assessed the association of insulin resistance as indicated by the homeostatic model assessment of insulin resistance (HOMA-IR) with inflammatory molecules, lipopolysaccharide-binding protein (LBP), high sensitivity C-reactive protein (hs-CRP), Tumor necrosis factor-α (TNF-α), and Interleukin-6 (IL-6) in urban young adolescents.</P> <P><B>Methods</B></P> <P>Seventy-six adolescents (36 subjects with HOMA-IR ≥ 2.6 and 40 subjects with HOMA-IR < 2.6) were included in the study. We assessed anthropometric and laboratory measures, such as BMI, blood pressure, insulin sensitivity, liver enzymes, and lipid profiles along with the aforementioned inflammatory biomarkers. The diagnostic accuracy of LBP, hs-CRP, TNF-α, and IL-6 for insulin resistance was evaluated by using the receiver operating characteristic (ROC) curve analysis.</P> <P><B>Results</B></P> <P>The mean age of the study subjects was 12.0 [12.0–13.0] y. Circulating LBP plasma concentration and hs-CRP were significantly increased in subjects with HOMA-IR ≥ 2.6 when compared with those with HOMA-IR < 2.6 (<I>P</I> < .0001). There was no difference in TNF-α or IL-6 concentrations between groups. Comparisons based on the area under the ROC curve for LBP, hs-CRP, TNF-α, and IL-6 with regard to insulin resistance (HOMA-IR ≥ 2.6) were 0.8384 (95% CI: 0.7380 to 0.9388), 0.7907 (95% CI: 0.6701 to 0.9113), 0.6207 (95% CI: 0.4770 to 0.7643), and 0.5763 (95% CI: 0.4285 to 0.7241), respectively.</P> <P><B>Conclusions</B></P> <P>Among LBP, hs-CRP, TNF-α, and IL-6, plasma LBP has the greatest diagnostic accuracy for insulin resistance in young adolescents. Prospective studies are warranted to delineate the value of LBP in the prediction of insulin resistance.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Plasma LBP is increased in young adolescents with insulin resistance and has the greatest diagnostic accuracy for insulin resistance. </LI> </UL> </P>

Role of Helix 8 in Dopamine Receptor Signaling

( Han-sol Yang ),( Ningning Sun ),( Xiaodi Zhao ),( Hee Ryung Kim ),( Hyun-ju Park ),( Kyeong-man Kim ),( Ka Young Chung ) 한국응용약물학회 2019 Biomolecules & Therapeutics(구 응용약물학회지) Vol.27 No.6

G protein-coupled receptors (GPCRs) are membrane receptors whose agonist-induced dynamic conformational changes trigger heterotrimeric G protein activation, followed by GRK-mediated phosphorylation and arrestin-mediated desensitization. Cytosolic regions of GPCRs have been studied extensively because they are direct contact sites with G proteins, GRKs, and arrestins. Among various cytosolic regions, the role of helix 8 is least understood, although a few studies have suggested that it is involved in G protein activation, receptor localization, and/or internalization. In the present study, we investigated the role of helix 8 in dopamine receptor signaling focusing on dopamine D1 receptor (D1R) and dopamine D2 receptor (D2R). D1R couples exclusively to Gs, whereas D2R couples exclusively to Gi. Bioinformatic analysis implied that the sequences of helix 8 may affect GPCR-G protein coupling selectivity; therefore, we evaluated if swapping helix 8 between D1R and D2R changed G protein selectivity. Our results suggest that helix 8 is not involved in D1R-Gs or D2R-Gi coupling selectivity. Instead, we observed that D1R with D2R helix 8 or D1R with an increased number of hydrophobic residues in helix 8 relative to wild-type showed diminished β-arrestin-mediated desensitization, resulting in increased Gs signaling.

Revised Triage and Surveillance Protocols for Temporary Emergency Department Closures in Tertiary Hospitals as a Response to COVID-19 Crisis in Daegu Metropolitan City

Han Sol Chung,Dong-Eun Lee,김종근,여인환,Chang Ho Kim,박정배,서강석,Sin-Yul Park,김정호,김균무,이숙희,전재천,Yang Hun Kim 대한의학회 2020 Journal of Korean medical science Vol.35 No.19

Background: When an emergency-care patient is diagnosed with an emerging infectious disease, hospitals in Korea may temporarily close their emergency departments (EDs) to prevent nosocomial transmission. Since February 2020, multiple, consecutive ED closures have occurred due to the coronavirus disease 2019 (COVID-19) crisis in Daegu. However, sudden ED closures are in contravention of laws for the provision of emergency medical care that enable the public to avail prompt, appropriate, and 24-hour emergency medical care. Therefore, this study ascertained the vulnerability of the ED at tertiary hospitals in Daegu with regard to the current standards. A revised triage and surveillance protocol has been proposed to tackle the current crisis. Methods: This study was retrospectively conducted at 6 level 1 or 2 EDs in a metropolitan city where ED closure due to COVID-19 occurred from February 18 to March 26, 2020. The present status of ED closure and patient characteristics and findings from chest radiography and laboratory investigations were assessed. Based on the experience from repeated ED closures and the modified systems that are currently used in EDs, revised triage and surveillance protocols have been developed and proposed. Results: During the study period, 6 level 1 or 2 emergency rooms included in the study were shut down 27 times for 769 hours. Thirty-one confirmed COVID-19 cases, of whom 7 died, were associated with the incidence of ED closure. Typical patient presentation with respiratory symptoms of COVID-19 was seen in less than 50% of patients, whereas abnormal findings on chest imaging investigations were detected in 93.5% of the study population. The chest radiography facility, resuscitation rooms, and triage area were moved to locations outside the ED, and a new surveillance protocol was applied to determine the factors warranting quarantine, including symptoms, chest radiographic findings, and exposure to a source of infection. The incidence of ED closures decreased after the implementation of the revised triage and surveillance protocols. Conclusion: Triage screening by emergency physicians and surveillance protocols with an externally located chest imaging facility were effective in the early isolation of COVID-19 patients. In future outbreaks of emerging infectious diseases, efforts should be focused toward the provision of continued ED treatment with the implementation of revised triage and surveillance protocols.