POSITIVE SOLUTIONS FOR MULTI-POINT BOUNDARY VALUE PROBLEM OF FRACTIONAL FUNCTIONAL DIFFERENTIAL EQUATIONS

Haihua Wang 한국전산응용수학회 2012 Journal of applied mathematics & informatics Vol.30 No.1

In this paper, we establish some sufficient conditions for the existence of positive solutions for a class of multi-point boundary value problem for fractional functional differential equations involving the Caputo fractional derivative. Our results are based on two fixed point theorems. Two examples are also provided to illustrate our main results.

POSITIVE SOLUTIONS FOR MULTI-POINT BOUNDARY VALUE PROBLEM OF FRACTIONAL FUNCTIONAL DIFFERENTIAL EQUATIONS

Wang, Haihua The Korean Society for Computational and Applied M 2012 Journal of applied mathematics & informatics Vol.30 No.1

In this paper, we establish some sufficient conditions for the existence of positive solutions for a class of multi-point boundary value problem for fractional functional differential equations involving the Caputo fractional derivative. Our results are based on two fixed point theorems. Two examples are also provided to illustrate our main results.

Study on mechanical behaviors of large diameter shield tunnel during assembling

Feng, Kun,Peng, Zuzhao,Wang, Chuang,He, Chuan,Wang, Qianshen,Wang, Wei,Cao, Songyu,Wang, Shimin,Zhang, Haihua Techno-Press 2018 Smart Structures and Systems, An International Jou Vol.21 No.5

In order to study the mechanical behavior of shield tunnel segments during assembly stage, the in-situ tests and FDM numerical simulation were conducted based on the Foguan Shiziyang Tunnel with large cross-section. Analysis for the load state of the assembling segments in different assembly steps as well as the investigation for the changing of inner forces and longitudinal stress of segments with assembling steps were carried out in this paper. By comparing the tested results with the simulated results, the conclusions and suggestions could be drawn as follows: (1) It is the most significant for the effects on axial force and bending moment caused by the assembly of adjacent segment, followed by the insertion of key segment while the effects in the other assembly steps are relative smaller. With the increasing value of axial force, the negative bending moment turns into positive and remains increasing in most monitored sections, while the bending moment of segment B1and B6 are negative and keeping increasing; (2) The closer the monitored section to the adjacent segments or the key segment, the more significant the internal forces response, and the monitored effects of key segment insertion are more obvious than that of calculation; (3) The axial forces are all in compression during assembling and the monitored values are about 1.5~1.75 times larger than the calculated values, and the monitored values of bending moment are about 2 times the numerical calculation. The bending moment is more sensitive to the segments assembly process compared with axial force, and it will result in the large bending moment of segments during assembling when the construction parameters are not suitable or the assembly error is too large. However, the internal forces in assembly stage are less than those in normal service stage; (4) The distribution of longitudinal stress has strong influence on the changing of the internal forces. The segment side surface and intrados in the middle of two adjacent jacks are the crack-sensitive positions in the early assembly stage, and subsequently segment corners far away from the jacks become the crack-sensitive parts either.

Molecular Cloning and Expression of Grass Carp MyoD in Yeast Pichia pastoris

Wang, Lixin,Bai, Junjie,Luo, Jianren,Chen, Hong,Ye, Xing,Jian, Qing,Lao, Haihua Korean Society for Biochemistry and Molecular Biol 2007 Journal of biochemistry and molecular biology Vol.40 No.1

MyoD, expressed in skeletal muscle lineages of vertebrate embryo, is one of muscle-specific basic helix-loop-helix (bHLH) transcription factors, which plays a key role in the determination and differentiation of all skeletal muscle lineages. In this study, a cDNA of grass carp MyoD was cloned and characterized from total RNA of grass carp embryos by RT-PCR. The full-length cDNA of grass carp MyoD is 1597 bp. The cDNA sequence analysis reveals an open reading frame of 825 bp coding for a protein of 275 amino acids, which includes a bHLH domain composed of basic domain (1-84th amino acids) and HLH domain (98-142th amino acids), without signal peptide. Then the MyoD cDNA of grass carp was cloned to yeast expression vector pPICZ$\alpha$A and transformed into P. pastoris GS115 strain, the recombinant MyoD protein with a molecular weight of about 31KD was obtained after inducing for 2d with 0.5% methanol in pH 8.0 BMGY medium, and the maximum yield was about 250 mg/L in shaking-flask fermentation. The results were expected to benefit for further studies on the crystal structure and physiological function of fish MyoD.

Polymorphism of Insulin-like Growth Factor I Gene in Six Chicken Breeds and Its Relationship with Growth Traits

Wang, Wenjun,Ouyang, Kehui,Ouyang, Jianhua,Li, Haihua,Lin, Shumao,Sun, Han Asian Australasian Association of Animal Productio 2004 Animal Bioscience Vol.17 No.3

The polymorphism of insulin-like growth factor I (IGF I) in 6 chicken breeds (total n=515) was detected by PCR-Pst IRFLP, and allele A (621 bp) or allele B (364 and 257 bp) were observed. In these chicken breeds, it was found that exotic chicken carried high frequencies of allele B, while Chinese native chicken breeds carried high frequencies of allele A. Meanwhile the role of IGF I was investigated in 133 Ningdu Yellow chicken and 162 Wanzhai Yellow chicken. Five growth traits were recorded for analyzing the association between IGFI gene polymorphism and performance. In both the Ningdu and Wanzhai Yellow breeds, body weight at 4 months was significantly higher with BB genotype than with AA genotype (p<0.05). Furthermore, body weight at 2 months in the Wanzhai Yellow breeds was also higher with BB genotype than with AA genotype (p<0.05). There were no differences among the genotypes for the other traits studied. Based on these results, it is necessary to do more studies on IGFI before making the IGFI locus into the application of maker-assisted selection programms.

Depositional and diagenetic controls on the reservoir quality of Upper Triassic Chang-7 tight oil sandstones, southwestern Ordos basin, China

Ai Wang,Dakang Zhong,Haihua Zhu,Lele Guo,Zhuopei Li,Yangjinfeng Jiang,Xueqi Yang,Rui Xie,Xiaowei Zheng 한국지질과학협의회 2019 Geosciences Journal Vol.23 No.3

The seventh oil layer of the Upper Triassic Yanchang Formation (Chang-7) tight oil sandstone reservoirs is a major exploration target. A significant amount of hydrocarbons has been discovered in these reservoirs in the southwestern Ordos basin in China. The Chang-7 tight sandstones are characterised as tight with low porosity, low permeability, and strong heterogeneity. This study investigates the sedimentary facies, diagenesis, and their impact on the reservoir quality of the Chang-7 tight oil sandstones. The sandstones were deposited in a deltaic-lacustrine depositional system. Three major depositional facies are identified consisting of delta front fed by braided rivers and meandering rivers, and slump turbidite fans. The depositional environment exerts a key control on reservoir quality. The distinct low-energy sedimentary environment produced fine to very fine-grained sandstones with high matrix and mica contents, characterised by low initial porosity and permeability. Diagenesis mainly comprised mechanical compaction and cementation by quartz, carbonate minerals and various clay minerals. The reservoir properties of the Chang-7 sandstones are generally poor, with porosity of 1.4–20.7% (average porosity 8.6%) and permeability of 0.001–116.7 mD (average 0.2 mD), which are attributed to significant compaction and cementation. Mechanical compaction was more important than cementation for reducing porosity, whereas secondary dissolution porosity was significant for the Chang-7 tight oil sandstones due to closer proximity to the underlying Chang-73 source rocks.

Diagentic features of illite in Upper Triassic Chang-7 tight oil sandstones, Ordos Basin

Ai Wang,Dakang Zhong,Haihua Zhu,Lele Guo,Yangjinfeng Jiang,Xueqi Yang,Rui Xie 한국지질과학협의회 2019 Geosciences Journal Vol.23 No.2

The Upper Triassic Chang-7 tight oil sandstones are the main tight clastic reservoirs in the Ordos Basin, central China. Illite is one of the most important cements affecting porosity and permeability of the tight oil sandstones, and this study focuses on different types of illitization and its relative formation time. The Chang-7 tight sandstones are mainly fine-grained lithic arkose and feldspar lithic sandstones, rich in mica and illite (hydrous mica). They are formed in distal delta front to semi-deep and deep lake facies, mainly deposited in a low energy environment. Porosity and permeability are very low (average porosity 8.58% and permeability 0.20 mD). The illite has many morphological characteristics and is multiphase, incorporating six types of illitization: hydrous mica, mica, and smectite illitization at the eodiagenetic stage, and kaolinite and K-feldspar illitization, and neoformation illite particles, at the mesodiagenetic stage. These different types of illitization are mainly controlled by sedimentary environment and provenance. Quartz overgrowth and diagenetic illites appear to be locally mutually exclusive, competing for detrital grain surfaces, but neoformation illite particles appear to form on the quartz overgrowth. The systematic study of Upper Triassic Chang-7 tight oil sandstones carried out here, enhances our understanding of illitization and the diagenetic model of the Ordos Basin, and contributes to reducing the exploration risk of continental tight sandstone reservoirs.

Enteric dysbiosis-linked gut barrier disruption triggers early renal injury induced by chronic high salt feeding in mice

Jingjuan Hu,Haihua Luo,Jieyan Wang,Wenli Tang,Junqi Lu,Shan Wu,Zhi Xiong,Guizhi Yang,Zhenguo Chen,Tian Lan,Hongwei Zhou,Jing Nie,Yong Jiang,Peng Chen 생화학분자생물학회 2017 Experimental and molecular medicine Vol.49 No.-

Chronic high-salt diet-associated renal injury is a key risk factor for the development of hypertension. However, the mechanism by which salt triggers kidney damage is poorly understood. Our study investigated how high salt (HS) intake triggers early renal injury by considering the ‘gut-kidney axis’. We fed mice 2% NaCl in drinking water continuously for 8 weeks to induce early renal injury. We found that the ‘quantitative’ and ‘qualitative’ levels of the intestinal microflora were significantly altered after chronic HS feeding, which indicated the occurrence of enteric dysbiosis. In addition, intestinal immunological gene expression was impaired in mice with HS intake. Gut permeability elevation and enteric bacterial translocation into the kidney were detected after chronic HS feeding. Gut bacteria depletion by non-absorbable antibiotic administration restored HS loadinginduced gut leakiness, renal injury and systolic blood pressure elevation. The fecal microbiota from mice fed chronic HS could independently cause gut leakiness and renal injury. Our current work provides a novel insight into the mechanism of HS-induced renal injury by investigating the role of the intestine with enteric bacteria and gut permeability and clearly illustrates that chronic HS loading elicited renal injury and dysfunction that was dependent on the intestine.

Bioinspired Fabric with Superhydrophilicity and Superoleophobicity for Efficient Oil/Water Separation

Liping Liang,Chenlu Wang,Hongfang Wang,Haihua Zhan,Xu Meng 한국섬유공학회 2018 Fibers and polymers Vol.19 No.9

The cotton fabric was modified with dopamine methacrylamide (DMA) based on mussel-inspired reaction and polymerized with zwitterionic sulfobetaine methacrylate (SBMA) through free radical polymerization reaction. The poly(DMA-SBMA) contained not only key chemical constituents of dopamine hydrochloride, which strongly adsorbed to fabric substrates, but also hydrophilic groups, providing a hydrophilic surface for fabric due to its strong interaction with water via electrostatic interactions. The chemical structure, surface topography, and surface wettability of the fabric were characterized by Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and contact angle experiments, respectively. The results showed that the water contact angle (WCA) of the treated fabric was ~0 o, whereas the underwater oil contact angle (OCA) was ~161 o, as compared to ~25 o for the control one. It is expected that as-prepared fabrics could be applied in oil/water separation due to such special superhydrophilicity and superoleophobicity.

Eucommia ulmoides Bark Protects Against Renal Injury in Cadmium-Challenged Rats

Erwei Liu,Lifeng Han,Jialong Wang,Wei He,Haihua Shang,Xiumei Gao,Tao Wang 한국식품영양과학회 2012 Journal of medicinal food Vol.15 No.3

Eucommia ulmoides Oliver is a perennial woody plant distributed widely in China. To characterize some major compounds in E. ulmoides bark extract, six compounds were identified via high-performance liquid chromatography qualitative analysis. E. ulmoides bark extract protects against cadmium-induced oxidative damage in rat kidneys. Two compounds of E. ulmoides bark extract, geniposide and genipin, which were identified both in serum and in kidney tissue, showed inhibitory effects on nitric oxide production. This study provides biological evidence supporting the usefulness of E. ulmoides bark against cadmium-induced toxic oxidative stress in rat kidney tissue.