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남지우,김동욱,배미영,박강순,김정현,노상률,최영일,김희종,장동욱,최소명,권영준,Hikita, S.,Yu, C.,Yoshimura, Y.,Kichimi, H. 성균관대학교 기초과학연구소 1998 論文集 Vol.49 No.-
We investigated the properties of BELLE Time Of Flight(TOF) counter using the data taken in Jan 98 beam test at Pi2 beam line at KEK 12 GeV proton synchrotron. Charge distributions from readout PMT were analysed in comparison with dE/dx distributions predicted by GEANT full simulation. Experimental setup of the beam test is described, then procedures of data analysis, Monte Carlo simulation and analysis results are also described.
Characteristics of second harmonic ECCD on CHS
yasuo Yoshimura,H. Matsushita,H. Igami,K. Nagasaki,K. Matsuoka,K. Ohkubo,K. Nagaoka,M. Isobe,S. Kobayashi,S. Okamura,S. Kubo,S. Nishimura,T. Minami,T. Akiyama,T. Notake,T. Shimozuma,A. Shimizu,C. Suzu 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.III
Second harmonic electron cyclotron current drive (ECCD) has been investigated on CHS (Compact Helical System) by using a 2-D steerable EC-beam injection system. The direction of the plasma current, which is the sum of bootstrap current and EC-driven current, is clearly reversed by a reversal of the EC-beam injection direction. The direction of driven current is consistent with expectation in the case of low-field side injection of EC wave. So far, a driven current up to 6 kA has been obtained when bootstrap current is less than 2 kA. It is confirmed that right-hand polarization and low density are effective for ECCD.
H. Matubara,K. Miharu,K. Kinoshita,K. Koyama,Yang Ye,K. Takahashi,I. Yoshimura,Y. Yamamoto,Y. Miura,Y. Kinoshita 한국생약학회 1998 Natural Product Sciences Vol.4 No.3
The analogues of lichen components showing anti-tyrosinase activities were synthesized. 4-Alkylresorcinol derivatives showed both the inhibitory activity and cytotoxicity in B-16 melanona cells at the doses of 10 mM to 1.2 mM. Resorcinol and 4-methylresorcinol showed the inhibitory effect with a low cytotoxicity at the doses of 2.5 mM and 600 μM among 4-alkylresorcinols, respectively. Some diphenylmethane derivatives (Type A, B, and C) had strong activities with a low cytotoxicity. While xanthene derivatives had no effect. Glucosides of 4,5-alkylresorcinol and the diphenylmethaney derivative (Type B) were prepared to decrease the cytotoxicity. As result, no effect were observed. Liposome of the diphenylmethane derivative (Type B) was prepared for the same purpose, and the later showed a remarkable effect at the dose at 1.5 μM with a low cytotoxicity.
Megumu, Yoshimura,A. Ito, H, Furue 경희대학교 2001 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.2001 No.1
In vivo patch-clamp recordings were made from substantia gelatinosa neurons in the rat spinal dorsal horn to analyze plastic changes in sensory transmission which underlie hyperalgesia induced in ovariectomized rats. All substantia gelatinosa neurons examined exhibited spontaneous excitatory postsynaptic currents (EPSCs) at a holding potential of -70 mV and inhibitory postsynaptic currents (IPSCs) at 0mV. Noxious or non-noxious mechanical stimuli applied to the ipsilateral hind limb elicited a barrage of EPSCs. The spontaneous and evoked EPSCs were depressed by a non-NMDA receptor antagonist, CNQX (10μM), suggesting that the mechanical sensory information is mediated by glutamate. The amplitude and frequency of EPSCs evoked by noxious or non-noxious stimuli were not significantly different. However, the amplitude of EFSCs evoked by noxious stimuli in ovariectomized rats was significantly larger than that of sham rats, although the frequency of EPSCs both in sham auld ovariectomized rat did not differ significantly. This plastic change in the amplitude of EPSCs may be due to a decrease in number of 5-HT receptor at C afferent terminals, which results in an increase in transmitter release from C afferent terminals.