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이승빈 ( Seung-bin Lee ),이주헌 ( Ju-heon Lee ),이계환 ( Gye-hwan Lee ),전경구 ( Gyeon-gu Jeon ) 한국정보처리학회 2017 한국정보처리학회 학술대회논문집 Vol.24 No.2
우리나라의 차량 범죄률은 국민들의 소득 증가와 더불어 계속해서 증가 중인 추세이다. 현재 상용화된 차량 번호판 인식은 시스템은 특정 위치에 고정되어 있고, 화면의 특정 영역에 물체가 들어와야만 번호판을 인식할 수 있다. 단순히 그 영역에 들어오지 못하면 번호판을 인식하지 못하고 지나치게 된다. 본 연구는 특정 영역에 구애받지 않고 장소, 화면 어디에서든 차량 번호판을 인식할 수 있게 딥러닝 기술을 응용하여 범죄차량을 찾아내는 기법을 제안한다. 또한 서버와 연동시켜 실시간으로 범죄차량의 위치를 파악, 주변 경찰들에게 연락을 주어 빠르게 범죄차량을 검거하는 서비스를 제공한다.
Study of Anisothermal Ageing of CANTiM Shape Memory Alloys by Positron Annihilation
Chung, C Y,LAM, C W H 대한금속재료학회(대한금속학회) 1996 METALS AND MATERIALS International Vol.2 No.2
The thermal-elastic property of high temperature CuAlNiMnTi shape memory alloys was found strongly affected by anisothermal ageing. With slow cycling (cycled at low heating and cooling rates), the transformation temperatures increase with the number of thermal cycle while the transformation enthalpy decreases and finally drop to zero, which indicated a total deterioration of the shape memory effect. Martensite stabilisation was found to be the cause of such deterioration. Positron Annihilation technique was employed to study the properties of the vacancies during the anisothermal ageing process. This was compared with the isothermal aged results. We propose that the changes in the quantity and characteristics of vacancies during anisothermal ageing are only responsible for the kinetics of the martensitic transformation. The result is the shift of transformation temperatures. However, the presence of vacancy agglomerations may have assisted the diffusion of atoms during ageing. Other factors like microstructural changes and atomic reordering will lead to the irreversible martensite stabilisation and make the transformation thermodynamically unfavourable.
Lam, V D,Tung, N T,Cho, M H,Park, J W,Jang, W H,Lee, Y P Institute of Physics [etc.] 2009 Journal of physics. D, applied physics Vol.42 No.11
<P>This report investigates the effect of the dielectric layer thickness on both magnetic and electric resonances of cut-wire-pair (CWP) structures in the microwave frequency regime. It was found that the resonances are sensitive to the thickness of the dielectric layer. As the thickness increases, the bandwidth of the magnetic resonance is slightly extended to a higher frequency, while the low-frequency edge of the electric-resonance band is remarkably shifted to a lower frequency. It was also found that the dependence of the magnetic resonance frequency on the dielectric layer thickness follows the trend of the closed formula based on the cavity model for the coupled metallic elements (Cai <I>et al</I> 2007 <I>Opt. Express</I> <B>15</B> 3333). In addition, we also studied the effect of the dielectric layer thickness on the left-handed behaviour of a combined structure consisting of CWP and continuous wire. The actual measurements are compared with the numerical simulation values to show a good coincidence.</P>
Fang, W.J.,Lam, K.O.,Ng, S.C.Y.,Choi, C.W.,Kwong, D.L.W.,Zheng, S.S.,Lee, V.H.F. Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.7
Background: To compare response evaluation criteria in solid tumours (RECIST) and volumetric evaluation (VE) for colorectal cancer with liver-limited metastasis. Patients and Methods: VE of liver metastases was performed by manual contouring before and after chemotherapy on 45 pairs of computed tomography (CT) images in 36 patients who suffered from metastatic colorectal cancer (mCRC) with liver metastasis only. Cohen kappa was used to compare the agreement between VE and RECIST. Pearson correlation was performed for their comparison after cubic root transformation of the aggregate tumor volumes. Logistic regression was done to identify clinical and radiographic factors to account for the difference which may be predictive in overall response (OR). Results: There were 16 partial response (PR), 23 stable disease (SD) and 6 progressive disease (PD) cases with VE, and 14 PR, 23 SD and 8 PD with RECIST. VE demonstrated good agreement with RECIST (${\chi}$=0.779). Discordant objective responses were noted in 6 pairs of comparisons (13.3%). Pearson correlation also showed excellent correlation between VE and RECIST ($r^2$=0.966, p<0.001). Subgroup analysis showed that VE was in slightly better agreement with RECIST for enlarging lesions than for shrinking lesions ($r^2$=0.935 and $r^2$=0.780 respectively). No factor was found predictive of the difference in OR between VE and RECIST. Conclusions: VE exhibited good agreement with RECIST. It might be more useful than RECIST in evaluation shrinking lesions in cases of numerous and conglomerate liver metastases.
Choi, D.,Moon, J. H.,Kim, H.,Sung, B. J.,Kim, M. W.,Tae, G. Y.,Satija, S. K.,Akgun, B.,Yu, C.-J.,Lee, H. W.,Lee, D. R.,Henderson, J. M.,Kwong, J. W.,Lam, K. L.,Lee, K. Y. C.,Shin, K. The Royal Society of Chemistry 2012 Soft matter Vol.8 No.32
<P>X-Ray and neutron reflectivity measurements on systems composed of a 1,2-dipalmitoyl-<I>sn</I>-glycero-3-phosphocholine (DPPC) bilayer and transcription-activating-factor derived peptides (TDPs) have allowed us to determine the mechanism of membrane translocation. By monitoring the structural changes of the bilayers caused by the binding of TDPs while systemically varying temperature and TDP concentration, our results revealed the detailed molecular structures of the stepwise interactions that occurred during the translocation of TDP across the lipid bilayers. While little indication of membrane perturbation was observed at low TDP concentrations, we found that the TDP movement across the membrane induced defect formations in the membrane at higher TDP concentrations.</P> <P>Graphic Abstract</P><P>X-Ray and neutron reflectivity have allowed us to reveal the detailed molecular structures of cell penetrating peptides across the supported lipid bilayers. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2sm25913c'> </P>
Ma, R. C. W.,Hu, C.,Tam, C. H.,Zhang, R.,Kwan, P.,Leung, T. F.,Thomas, G. N.,Go, M. J.,Hara, K.,Sim, X.,Ho, J. S. K.,Wang, C.,Li, H.,Lu, L.,Wang, Y.,Li, J. W.,Wang, Y.,Lam, V. K. L.,Wang, J.,Yu, W.,Ki Springer-Verlag 2013 Diabetologia Vol.56 No.6
<P><B>Aims/hypothesis</B></P><P>Most genetic variants identified for type 2 diabetes have been discovered in European populations. We performed genome-wide association studies (GWAS) in a Chinese population with the aim of identifying novel variants for type 2 diabetes in Asians.</P><P><B>Methods</B></P><P>We performed a meta-analysis of three GWAS comprising 684 patients with type 2 diabetes and 955 controls of Southern Han Chinese descent. We followed up the top signals in two independent Southern Han Chinese cohorts (totalling 10,383 cases and 6,974 controls), and performed in silico replication in multiple populations.</P><P><B>Results</B></P><P>We identified <I>CDKN2A/B</I> and four novel type 2 diabetes association signals with <I>p</I> < 1 × 10<SUP>−5</SUP> from the meta-analysis. Thirteen variants within these four loci were followed up in two independent Chinese cohorts, and rs10229583 at 7q32 was found to be associated with type 2 diabetes in a combined analysis of 11,067 cases and 7,929 controls (<I>p</I><SUB>meta</SUB> = 2.6 × 10<SUP>−8</SUP>; OR [95% CI] 1.18 [1.11, 1.25]). In silico replication revealed consistent associations across multiethnic groups, including five East Asian populations (<I>p</I><SUB>meta</SUB> = 2.3 × 10<SUP>−10</SUP>) and a population of European descent (<I>p</I> = 8.6 × 10<SUP>−3</SUP>). The rs10229583 risk variant was associated with elevated fasting plasma glucose, impaired beta cell function in controls, and an earlier age at diagnosis for the cases. The novel variant lies within an islet-selective cluster of open regulatory elements. There was significant heterogeneity of effect between Han Chinese and individuals of European descent, Malaysians and Indians.</P><P><B>Conclusions/interpretation</B></P><P>Our study identifies rs10229583 near <I>PAX4</I> as a novel locus for type 2 diabetes in Chinese and other populations and provides new insights into the pathogenesis of type 2 diabetes.</P><P><B>Electronic supplementary material</B></P><P>The online version of this article (doi:10.1007/s00125-013-2874-4) contains peer-reviewed but unedited supplementary material, which is available to authorised users.</P>
Tang, W.K.,Wong, K.B.,Lam, Y.M.,Cha, S.S.,Cheng, C.H.K.,Fong, W.P. North-Holland Pub ; Elsevier Science Ltd 2008 FEBS letters Vol.582 No.20
The crystal structure of seabream antiquitin in complex with the cofactor NAD<SUP>+</SUP> was solved at 2.8A resolution. The mouth of the substrate-binding pocket is guarded by two conserved residues, Glu120 and Arg300. To test the role of these two residues, we have prepared the two mutants E120A and R300A. Our model and kinetics data suggest that antiquitin's specificity towards the substrate α-aminoadipic semialdehyde is contributed mainly by Glu120 which interacts with the α-amino group of the substrate. On the other hand, Arg300 does not have any specific interaction with the α-carboxylate group of the substrate, but is important in maintaining the active site conformation.
Detailed Numerical Study of Cut-wire Pair Structures
이영백,N. T. Tung,J. W. Park,V. D. Lam,W. H. Jang 한국물리학회 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.56 No.4
We systematically study the transmission properties of metallic cut-wire pair (CWP) structure,using the transfer-matrix method and the commercial code, CST Microwave Studio. The electric and the magnetic resonances of CWP structure are demonstrated by the effective medium anal-yses. The corresponding effective permittivity and permeability are calculated from the complex scattering parameters by using the standard retrieval procedure. In addition, the dependence of the transmission properties and the resonance frequencies on the periodicities and the shape of CWP are examined. Moreover, the influence of background medium and the properties of the dielectric spacer are also discussed.