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      • KCI등재

        Methodology of uncertainty analysis prediction based on multi-well data fusion

        Huan Jie Zhang,Kai Wei,Alain P. Tchameni,G. Ben-Kane 한국자원공학회 2018 Geosystem engineering Vol.21 No.3

        During drilling activities, geological parameters of a well to be drilled (target well) can be predicted within a limited interval based on multi-well data fusion which aims at ensuring a drilling safety, enhancement of drilling efficiency, reduction of drilling cost as well as acquiring accurate measurements in respect to Oil and Gas protection layers. This work presents a method of uncertainty analysis prediction of pressures using fusion data (formation pressures) from adjacent multi-well. The Eaton method, effective stress theory, and mathematical confidence interval were the various methods used to establish the formation pressure matrix of the target well. The results revealed that due to the complexity and variability of the formations, data interpretation errors of the geological parameters were inevitable. Therefore, the probability density distribution function was established through stratigraphy, probability statistics, and information diffusion. Moreover, the real value of the wells’ formation pressure (target well) was within the distribution interval of multi-well data fusion. Hence, the developed method cannot only effectively reduce the interval of geological parameter of the target well but also enhance the accuracy of parameters prediction.

      • KCI등재

        Phosphorylation of DYNLT1 at Serine 82 Regulates Microtubule Stability and Mitochondrial Permeabilization in Hypoxia

        Xue Xu,Yue-sheng Huang,Qiong Zhang,Jiong-yu Hu,Dong-xia Zhang2,Xu-pin Jiang,jie-zhi Jia,Jing-ci Zhu 한국분자세포생물학회 2013 Molecules and cells Vol.36 No.4

        Hypoxia-induced microtubule disruption and mitochondrial permeability transition (mPT) are crucial events leading to fatal cell damage and recent studies showed that microtubules (MTs) are involved in the modulation of mitochondrial function. Dynein light chain Tctex-type 1 (DYNLT1) is thought to be associated with MTs and mitochondria. Previously we demonstrated that DYNLT1 knockdown aggravates hypoxia-induced mitochondrial permeabilization, which indicates a role of DYNLT1 in hypoxic cytoprotection. But the underlying regulatory mechanism of DYNLT1 remains illusive. Here we aimed to investigate the phosphorylation alteration of DYNLT1 at serine 82 (S82) in hypoxia (1% O2). We therefore constructed recombinant adenoviruses to generate S82E and S82A mutants, used to transfect H9c2 and HeLa cell lines. Development of hypoxia-induced mPT (MMP examining, Cyt c release and mPT pore opening assay), hypoxic energy metabolism (cellular viability and ATP quantification), and stability of MTs were examined. Our results showed that phosph-S82 (S82-P) expression was increased in early hypoxia; S82E mutation (phosphomimic) aggravated mitochondrial damage, ele-vated the free tubulin in cytoplasm and decreased the cellular viability; S82A mutation (dephosphomimic) seemed to diminish the hypoxia-induced injury. These data suggest that DYNLT1 phosphorylation at S82 is involved in MTs and mitochondria regulation, and their interaction and cooperation contribute to the cellular hypoxic tolerance. Thus, we provide new insights into a DYNLT1 mechanism in stabilizing MTs and mitochondria, and propose a potential therapeutic target for hypoxia cytoprotective studies.

      • KCI등재

        Exploring the Impact of Live Commercial Anchors on BusinessPerformance and Survival Strategy: Focusing on Resource Configuration and Environmental Choice 1

        Li-Jie ZHANG(Li-Jie ZHANG),Fei HUANG(Fei HUANG) 동아시아경상학회 2022 The East Asian Journal of Business Economics Vol.10 No.4

        Purpose – Through the analysis and research of different characteristics and related mechanisms of live commerce anchors, this paper aimed to help live commerce anchors to strengthen their characteristic advantages, beautify the live broadcast environment, improve resource allocation and enhance business performance, so as to help live commerce anchors to achieve better high-quality development. Research design, data, and methodology – This study was conducted by sample survey method on 361 live commercial anchors who have experience in using major online shopping malls for more than one year. Data analysis methods were frequency analysis, confirmatory factor analysis, reliability analysis, correlation analysis, and structural equation model analysis. Result – Hypothesis 1 through Hypothesis 5 were all supported. The results of this study suggest that professionalism and mutual entertainment of live commercial anchors have a significant impact on business performance, survival strategy, resource allocation and environment selection. The resource allocation and environment selection of live commercial anchors play a mediating role in the professionalism and mutual entertainment of live commercial anchors on business performance and survival strategy. Conclusion –The results implied that the professionalism and inter entertainment of live commercial anchors have a positive impact on business performance and survival strategy. In the new situation, live commercial anchors should further improve their professionalism and mutual entertainment, so as to achieve better development.

      • KCI등재

        Effect of Motivation Type and Reward Uncertainty on Consumers' Marketing Promotion Participation

        Zhang, Yan-Jie,Lee, Youseok,Kim, Sang-Hoon Korean Marketing Association 2017 ASIA MARKETING JOURNAL Vol.19 No.3

        The current research proposes to fill a research gap by testing how reward uncertainty, different types of motivation, as well as individual risk-taking attitude affect consumers' promotion participation. Being offered with an uncertain reward, relative to individuals with extrinsic motivation, individuals with intrinsic motivation will have greater intention to participate in marketing promotion. In contrast, being offered with a certain reward, relative to individuals with intrinsic motivation, individuals with extrinsic motivation will have greater intention to participate in marketing promotion. This effect arises only among consumers having a low level of risk-taking attitude. For consumers having a high level of risk-taking attitude, their participation intention shows no significant difference between the two motivation type groups, under both certain and uncertain reward conditions. With an understanding of how consumer's response heterogeneously to promotions involving rewards, marketers can better understand not only how to use this promotional tactic more effectively, but also how to better allocate their budget for promotions.

      • Reachable set estimation for discrete-time switched nonlinear positive systems with time delays

        Jie Zhang,Yuangong Sun 제어로봇시스템학회 2019 제어로봇시스템학회 국제학술대회 논문집 Vol.2019 No.10

        This paper studies the reachable set estimation for discrete-time switched nonlinear positive systems with time delays whose vector fields are homogeneous of degree one and order-preserving. By using a new analytical technique, we establish necessary and sufficient conditions such that all solutions of the system exponentially converge to a ball under average dwell time switching. Compared with the existing results, the average dwell time given in this paper is less conservative. Finally, numerical examples are given to illustrate the effectiveness of our results.

      • Expression and Significance of ER, PR, VEGF, CA15-3, CA125 and CEA in Judging the Prognosis of Breast Cancer

        Zhang, Su-Jie,Hu, Yi,Qian, Hai-Li,Jiao, Shun-Chang,Liu, Zhe-Feng,Tao, Hai-Tao,Han, Lu Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.6

        Objective: To explore the expression and significance of estrogen receptor (ER), progestrone receptor (PR), vascular endothelial growth factor (VEGF), CA15-3, CA125 and carcinoma embryonic antigen (CEA) expression in judging the prognosis of breast cancer. Materials and Methods: Sixty-five patients with breast cancer undergoing operations in the general surgery department were considered as the observation group, and 50 healthy outpatients of our hospital as the control group. Cubital venous blood was drawn in the morning from fasting patients in the two groups and chemiluminescence immunoassays were used to detect the levels of CA15-3, CA125 and CEA in serum. The follow-up duration was from 4 months to 2 years, and change in levels of the indicators was detected by dynamically drawing blood. After surgery, cancer tissue samples of patients in observation group remained on file (the non-recurrent patients were biopsied). Immunohistochemistry was applied to determine the expression of ER, PR and VEGF in tissue. Results: The effective rate of 12 patients with negative ER and PR expression was 33.3% in the observation group, being associated with prognosis to varying extents. Serum CA15-3, CA125 and CEA in the observation group were all significantly higher than in control group (p<0.01). With increase in pathological staging, levels of serum CA15-3, CA125 and CEA gradually increased (p<0.01). Levels in patients with lymph node metastasis were markedly higher than in those without (p<0.01). In addition, values with distal lymph node metastasis were notably higher than with adjacent lymph node metastasis (p<0.01). The postoperative follow-up results revealed that positive VEGF and levels of serum VEGF, CA15-3, CA125 and CEA in recurrence group were obviously higher than in non-recurrence group (p<0.01). Conclusions: Joint detection of ER and PR expression as well as levels of serum VEGF, CA15-3, CA125 and CEA is meaningful and can guide the diagnosis and treatment for breast cancer.

      • Research on the Use of RFID Technology in Cigarette Production

        Jie Zhang,Miaomiao Zhao 보안공학연구지원센터 2016 International Journal of Multimedia and Ubiquitous Vol.11 No.8

        With regard to the cigarette manufacturing’s demand for modern management, to protect the integrity and reliability of the cigarette production processing data, the proposed RFID application in cigarette production system, building on the basis of RFID security controlled digital information system platform, the system covers the entire process of cigarette production and can realize the control and management of cigarette production and optimize the improvement on the basis of binary ALOHA anti-collision algorithm. It can also improve RFID’s recognition accuracy to achieve the basic information for cigarette products in the process of digitization accuracy.

      • A study of binomial AR(1) process with an alternative generalized binomial thinning operator

        Zhang Jie,Wang Jiacong,Tai Zhiyan,Dong Xiaogang 한국통계학회 2023 Journal of the Korean Statistical Society Vol.52 No.1

        In order to describe the fnite-range integer-valued time series data with dependent structure and excess zeros, we introduce a new binomial AR(1) process with an alternative generalized binomial thinning operator. Some probabilistic and statistical properties of this model are derived. Model parameters are estimated by conditional least squares method and conditional maximum likelihood method. The consistency and asymptotic normality of these estimators are studied. In addition, a real data analysis shows a better performance of the proposed model than other existing models.

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