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RISS 인기검색어
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- 저자 : Guoren Huang (검색결과 3 건)
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Bocui Song,Guoren Huang,Ying Xiong,Jingbo Liu,Linli Xu,Zhenning Wang,Gen Li,Jing Lu,Shuang Guan 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.11
The aim of this study was to evaluate the effect of salidroside on lipopolysaccharide (LPS)-induced nitric oxide (NO) and prostaglandin E2 (PGE2) production in RAW 264.7 macrophages and related anti-inflammatory mechanism. PGE2 production was measured by enzyme-linked immunosorbent assay (ELISA); NO production was tested by Griess reagent. Inducible nitric oxidesynthase (iNOS) and COX-2 were determined by RT-PCR and Western blot analysis; IjB and P-IjB protein express were detected by Western blot analysis; cytosolic free Ca2+ ([Ca2 + ]i)was measured by a fluorescent microscope. The data showed salidroside inhibited LPS-induced NO and PGE2 production and reduced iNOS and COX-2 protein expression in RAW 264.7 macrophages. Consistent with these observations, salidroside inhibited LPS-induced cytosolic free Ca2 + concentration ([Ca2 +]i) elevation. In addition, we further investigated signal transduction mechanisms and found that the activation of NF-jBwas suppressed by salidroside in a dose-dependent manner. These results suggest that salidroside suppresses NO and PGE2 production by inhibiting iNOS and COX-2 protein expression, level of [Ca2 + ]i, and activation of NF-jB signal transduction pathway.
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Guorui Xiao,Wei He,Tonghan Yang,Guoren Huang,Tao Wang,Jinhui Huang 한국물리학회 2019 Current Applied Physics Vol.19 No.4
The bulk polycrystalline samples of La0.67Ca0.13Ba0.2Mn1-xCoxO3 (x=0, 0.02, 0.04, 0.06, 0.08, 0.1) have been prepared by conventional solid-state reaction method. X-ray powder diffraction shows that all samples crystallize in the rhombohedral structure with R3¯c space group symmetry. The ratio of Co3+/Co4+ gradually increases with increasing Co doping composition, which was determined by XPS analysis. The temperature and applied magnetic field dependence of magnetization were carried out. All samples exhibit a FM-PM transition at the Curie temperature TC, which decreases from 312 K to 223 K with increasing Co composition. Critical analysis shows that the estimated critical exponents β, γ and δ are in between the theoretically predicted values for 3DHeisenberg and mean-field theory models for all samples. The magnetocaloric effect has been calculated from isothermal magnetization curve at various temperatures near TC. The maximum magnetic entropy changes -ΔSmax under applied magnetic field of 1.6 T were found to be 3.18 J kg−1 K−1, 2.47 J kg−1 K−1 and 2.68 J kg−1 K−1 respectively for x=0, 0.02 and 0.04 composition, which will be an interesting compound for application materials working as magnetic refrigerants near room temperature.
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Chunmei Chen,Wei He,Lijing Ding,Xiaohui Song,Jinhui Huang,Tao Wang,Guoren Huang 한국물리학회 2018 Current Applied Physics Vol.18 No.3
The structural, elastic, thermodynamic and electronic properties of the Ti15−xMoxSn compounds were systematically investigated by means of first-principles calculations based on the density functional theory (DFT). The calculated results demonstrate the Ti15−xMoxSn compounds still remain the stable β phase structure. The calculation of cohesive energy shows that the structural stability of the Ti15−xMoxSn compounds increases apparently with the increase of Mo content. According to Hooke's law, the single crystal elastic constants were obtained and show that all the calculated compounds keep mechanical stability. Then the bulk modulus B, shear modulus G, Young's modulus E and Poisson's ratio ν of polycrystalline aggregates were calculated at zero pressure. The calculated results show that among these Ti15−xMoxSn compounds, Ti4Mo11Sn exhibits the largest stiffness while Ti12Mo3Sn shows the greatest ductility. The compounds Ti12Mo3Sn and Ti11Mo4Sn with the two lowest elastic Young's modulus of 61.01 GPa and 65.59 GPa are expected to be promising metallic biomaterials for implant applications. Besides, the Debye temperature ΘD and the electronic density of states (DOS) are also investigated and discussed.
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