Seismic performance of eccentrically braced frames with high strength steel combination

Ming Lian,Mingzhou Su,Yan Guo 국제구조공학회 2015 Steel and Composite Structures, An International J Vol.18 No.6

Eccentrically braced frames (EBFs) often use conventional steel with medium yield strength. This system requires structural members with large cross-sections for well seismic behavior, which leads to increased material costs. In eccentrically braced frames with high strength steel combination (HSS-EBFs), links use Q345 steel (specified nominal yield strength 345 MPa), braces use Q345 steel or high strength steel while other structural members use high strength steel (e.g., steel Q460 with the nominal yield strength of 460 MPa or steel Q690 with the nominal yield strength of 690 MPa). For this approach can result in reduced steel consumption and increased economic efficiency. Several finite element models of both HSS-EBFs and EBFs are established in this paper. Nonlinear hysteretic analyses and nonlinear time history analyses are conducted to compare seismic performance and economy of HSS-EBFs versus EBFs. Results indicate that the seismic performance of HSS-EBFs is slightly poorer than that of EBFs under the same design conditions, and HSS-EBFs satisfy seismic design codes and reduce material costs.

Decrease of Oxygen Vacancy by Zn-Doped for Improving Solar-Blind Photoelectric Performance in β-Ga2O3 Thin Films

Daoyou Guo,Xinyuan Qin,Ming Lv,Haoze Shi,Yuanli Su,Guosheng Yao,Shunli Wang,Chaorong Li,Peigang Li,Weihua Tang 대한금속·재료학회 2017 ELECTRONIC MATERIALS LETTERS Vol.13 No.6

Highly (201) oriented Zn-doped β-Ga2O3 thin films with differentdopant concentrations were grown on (0001) sapphire substrates byradio frequency magnetron sputtering. With the increase of Zn dopantconcentration, the crystal lattice expands, the energy band gap shrinks,and the oxygen vacancy concentration decreases. Both the metalsemiconductor metal (MSM) structure photodetectors based on thepure and Zn-doped β-Ga2O3 thin films exhibit solar blind UVphotoelectric property. Compared to the pure β-Ga2O3 photodetector,the Zn-doped one exhibits a lower dark current, a higher photo/darkcurrent ratio, a faster photoresponse speed, which can be attributed tothe decreases of oxygen vacancy concentration.

Association Between C1019T Polymorphism in the Connexin 37 Gene and Helicobacter Pylori Infection in Patients with Gastric Cancer

Jing, Yuan-Ming,Guo, Su-Xia,Zhang, Xiao-Ping,Sun, Ai-Jing,Tao, Feng,Qian, Hai-Xin Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5

Objective: To investigate the association between the connexin 37 C1019T polymorphism and Helicobacter pylori infection in patients with gastric cancer. Methods: 388 patients with gastric cancer (GC), 204 with chronic superficial gastritis (CSG) were studied. H. pylori was detected by gastric mucosal biopsies biopsy dyeing method. Connexin 37 gene polymorphism 1019 site genotypes were determined by gene sequencing technology. Genotypes and alleles frequencies were compared. Results: (1) Connexin37 gene 1019 site distribution frequency (CC type, TC type, TT type) in the CSG group was 18.1%, 45.1% and 36.8%; in the stomach cancer group it was 35.1%, 45.9% and 19.%, conforming to the Hardy-Weinberg euilibrium. (2) In comparison with CSG group, the frequency of Connexin37 C allele was higher in the gastric cancer group (58.0% vs 40.7%, OR = 2.01, 95%CI = 1.58-2.57, P < 0.01). The prevalence of gastric cancer risk was significantly increased in the carriers of C allele (CC+TC) than in TT homozygote (OR = 2.47, 5%CI = 1.68- 3.610. (3) Gastric cancer patients complicated with Hp infection 211 cases, gastric cancer group of the male patients with HP positive patients with 187 cases, 40 cases of female patients with negative patients, 24 cases were HP positive, negative in 137 cases, control group male patients, 28 cases were Hp positive, negative in 95 patients, female patients with Hp positive 6 cases, 75 cases were negative. On hierarchical analysis, the male group OR value was 15.9 (95%CI to 9.22-27.3), and the female OR was 2.19 (95%CI 0.88-5.59), indicating a greater contribution in males (P <0.01). After elimination of gender effects, positive HP and gastric cancer were closely related (OR 8.82, 95% CI: 5.45-14.3). (4) The distribution frequency of C allele in patients with Hp infection was much higher than that in Hp negative cases in the GC group (64.5% vs 47.0%, OR = 2.05, 95%CI = 1.54-2.74, P < 0.01). Compared with TT homozygotes, (CC+TC) genotype prevalence of gastric cancer risk increased significantly (OR = 2.96, 5%CI = 1.76-2.99 ). Conclusion: The T allele in the connexin37 gene might not only be associated with gastric cancer but also with H. pylori infection.

Induction Chemotherapy Followed by Concurrent Chemoradiotherapy Versus Concurrent Chemoradiotherapy with or without Adjuvant Chemotherapy for Locoregionally Advanced Nasopharyngeal Carcinoma: Meta-analysis of 1,096 Patients from 11 Randomized Controlled

Liang, Zhong-Guo,Zhu, Xiao-Dong,Tan, Ai-Hua,Jiang, Yan-Ming,Qu, Song,Su, Fang,Xu, Guo-Zeng Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1

Purpose: To evaluate the efficacy and toxicity of induction chemotherapy followed by concurrent chemoradiotherapy (the treatment group) versus concurrent chemoradiotherapy with or without adjuvant chemotherapy (the control group) for locoregionally advanced nasopharyngeal carcinoma. Methods: The search strategy included Pubmed, Embase, the Cochrane Library, China National Knowledge Internet Web, Chinese Biomedical Database and Wanfang Database. We also searched reference lists of articles and the volumes of abstracts of scientific meetings. All randomized controlled trials were included for a meta-analysis performed with RevMan 5.1.0. The Grading of Recommendations Assessment, Development, and Evaluation system (GRADE) was used to rate the level of evidence. Results: Eleven studies were included. Risk ratios of 0.99 (95%CI 0.72-1.36), 0.37 (95%CI 0.20-0.69), 1.08 (95%CI 0.84-1.38), 0.98 (95%CI 0.75-1.27) were observed for 3 years overall survival, 3 years progression-free survival, 2 years loco-regional failure-free survival and 2 years distant metastasis failure-free survival. There were no treatment-related deaths in either group in the 11 studies. Risk ratios of 1.90 (95%CI 1.24-2.92), 2.67 (95%CI 0.64-11.1), 1.04 (95%CI 0.79-1.37), 0.98 (95%CI 0.27-3.52) were found for grade 3-4 leukopenia, grade 3-4 thrombocytopenia, grade 3-4 mucous membrane, and grade 3-4 hepatic hematologic and gastrointestinal toxicity, the most significant toxicities for patients. Conclusion: Compared with the control group, induction chemotherapy followed by concurrent chemoradiotherapy was well tolerated but could not significantly improve prognosis in terms of overall survival, loco-regional failure-free survival or distant metastasis failure-free survival.

Gut Microbiota Community and Its Assembly Associated with Age and Diet in Chinese Centenarians

( Fang Wang ),( Ting Yu ),( Guo Hong Huang ),( Da Cai ),( Xiaolin Liang ),( Hai Yan Su ),( Zhenjun Zhu ),( Danlei Li ),( Yang Yang ),( Pei Hong Shen ),( Rui Feng Mao ),( Lian Yu ),( Mou Ming Zhao ),( 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.8

Increasing evidence suggests that gut microbiota underpin the development of health and longevity. However, our understanding of what influences the composition of this community of the longevous has not been adequately described. Therefore, illumina sequencing analysis was performed on the gut microbiota of centenarians (aged 100-108 years; RC) and younger elderlies (aged 85-99 years; RE) living in Bama County, Guangxi, China and the elderlies (aged 80-92 years; CE) living in Nanning City, Guangxi, China. In addition, their diet was monitored using a semiquantitative dietary questionary (FFQ 23). The results revealed the abundance of Roseburia and Escherichia was significantly greater, whereas that of Lactobacillus, Faecalibacterium, Parabacteroides, Butyricimonas, Coprococcus, Megamonas, Mitsuokella, Sutterella, and Akkermansia was significantly less in centenarians at the genus level. Both clustering analysis and UniFraq distance analysis showed structural segregation with age and diet among the three populations. Using partial least square discriminate analysis and redundancy analysis, we identified 33 and 34 operational taxonomic units (OTUs) as key OTUs that were significantly associated with age and diet, respectively. Age-related OTUs were characterized as Ruminococcaceae, Clostridiaceae, and Lachnospiraceae, and the former two were increased in the centenarians; diet-related OTUs were classified as Bacteroidales, Lachnospiraceae, and Ruminococcaceae. The former two were deceased, whereas the later one was increased, in the high-fiber diet. The age and high-fiber diet were concomitant with changes in the gut microbiota of centenarians, suggesting that age and high-fiber diet can establish a new structurally balanced architecture of gut microbiota that may benefit the health of centenarians.

Enrichment of iron element from sulfur-containing iron tailings by S-HGMS technology

Ya-qian Zhou,Rui-ming Yang,Peng-hui Guo,Su-qin Li,Yi Xing 한국초전도저온공학회 2021 초전도와 저온공학 Vol.23 No.3

Comprehensive utilization of sulfur-containing iron tailings (SIT) not only solves environmental problems but also creates certain economic value. The iron element from SIT was enriched by the superconducting high gradient magnetic separation (S-HGMS) technology in this study. In the experiments, the total iron content (TFe) was increased from 26.3% to 60.5% with the total sulfur content (TS) of 5.9% under the optimal parameters, i.e., a magnetic flux density of 0.4 T, a slurry flow rate of 1500 mL/min. The high-quality sulfur-containing material with TFe of more than 60% was obtained, which can be used for preparing high-sulfur free cutting steel. The S-HGMS technology can realize the resource utilization of iron tailings with high added value.

Investigation on Pharmacokinetics, Tissue Distribution and Excretion of a Novel Anticancer Platinum Compound by Inductively Coupled Plasma Mass Spectrometry after Intravenous Administration to Rats

Qing-fei Liu,Xue Li,Qiang Su,Guo-an Luo,Yi-ming Wang,Wei-ping Liu 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.11

SM54111 [cis-3, 5-diisopropylsalylic cyclohexanodiaminoplatinum (Ⅱ), Saliplatin] is a novel platinum compound with encouraging anticancer effect. In order to get more useful information in multiple species for the security evaluation, dosage design, and drug delivery design, its pharmacokinetic behaviors in rats after intravenous administration were investigated in this study. Based on its pharmacokinetics in plasma, the distribution of SM54111 in heart, liver, spleen, lung, kidney, brain, adipose, testicle, or ovaries of rats sampled at 0.5 h, 1 h, and 3 h after intravenous administration were determined utilizing inductively coupled plasma mass spectrometry (ICP-MS). Its amounts in urine and feces were determined at 8 sampling times till 96 h as well. It was proved that SM54111 fitted open two-compartment model in rats, with wide distribution in tissues and slow excretion. Its reasonable pharmacokinetic properties in rats make this novel platinum compound worthy of further research and development.

Enrichment of iron element from sulfur-containing iron tailings by S-HGMS technology

Zhou, Ya-qian,Yang, Rui-ming,Guo, Peng-hui,Li, Su-qin,Xing, Yi The Korean Society of Superconductivity and Cryoge 2021 한국초전도저온공학회논문지 Vol.23 No.3

Comprehensive utilization of sulfur-containing iron tailings (SIT) not only solves environmental problems but also creates certain economic value. The iron element from SIT was enriched by the superconducting high gradient magnetic separation (S-HGMS) technology in this study. In the experiments, the total iron content (TFe) was increased from 26.3% to 60.5% with the total sulfur content (TS) of 5.9% under the optimal parameters, i.e., a magnetic flux density of 0.4 T, a slurry flow rate of 1500 mL/min. The high-quality sulfur-containing material with TFe of more than 60% was obtained, which can be used for preparing high-sulfur free cutting steel. The S-HGMS technology can realize the resource utilization of iron tailings with high added value.

Redeposition mechanism on silicon oxide layers during selective etching process in 3D NAND manufacture

Zihan Zhou,Yunwen Wu,Huiqin Ling,Jie Guo,Su Wang,Ming Li 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.119 No.-

3D NAND flash memory with vertically stacked cells has been developed to break through the limits oftechnology nodes. However, during the selective etching process, it is difficult to ensure the byproductsdiffuse away from the trenches in the multistacked layers. Once saturated, the byproduct causes abnormalredeposition on the SiO2 layers. This problem has restricted the development of high-density 3DNAND memory. To solve this problem, the composition and formation mechanism of the redepositedlayer must be clarified. In this study, a ternary-wafer system comprising a Si3N4/SiO2/Si3N4 stack was fabricatedto study the redeposition mechanism, and the morphology, elastic properties, and chemical compositionof the redeposited layer were clarified. The redeposited layer consists of spherical particles withelastic surfaces (average Young’s modulus of 24.17 GPa). The particles were confirmed to comprise colloidalsilica gel covered by silanols. By considering the chemistry of silica, the redeposition mechanismwas proposed as follows: colloidal silica gel is formed by the aggregation of silicic acids from Si3N4 etching,which adsorb onto the SiO2 layer through oxide bridges and hydrogen bonding. Our work will contributeto the development of high-density 3D NAND memory.

Cordblood-Based High-Throughput Screening for Deafness Gene of 646 Newborns in Jinan Area of China

Shou-Xia Li,Ding-Li Chen,Su-Bin Zhao,Li-Li Guo,Hai-Qin Feng,Xiao-Fang Zhang,Li-Li Ping,Zhi-Ming Yang,Cai-Xia Sun,Gen-Dong Yao 대한이비인후과학회 2015 Clinical and Experimental Otorhinolaryngology Vol.8 No.3

Objectives. Infants with slight/mild or late-onset hearing impairment might be missed in universal newborn hearing screening (UNHS). We identified the mutation hot spot of common deaf gene in the newborns in Jinan area population by screening the mutation spot with neonate cord blood, in order to make clear whether the neonate cord blood for screening is feasible. Methods. Six hundred and forty-six newborns were subjected to both UNHS and genetic screening for deafness by using neonate cord blood. The newborn genetic screening targeted four deafness-associated genes, which were commonly found in the Chinese population including gap junction beta-2 protein (GJB2), gap junction beta-3 protein (GJB3), solute carrier family 26 member 4 (SLC26A4), and mtDNA 12S rRNA. The most common 20 spot mutations in 4 deaf genes were detected by MassARRAY iPLEX platform and mitochondrial 12S rRNA A1555G and C1494T mutations were sequenced using Sanger sequencing. Results. Among the 646 newborns, 635 cases passed the UNHS and the other 11 cases (1.7%) did not. Of the 11 failures, two cases were found to carry homozygous GJB2 p.R143W pathogenic mutation, one case was found to have heterozygous GJB2 235delC mutation, and another one case carried heterozygous GJB3 p.R180X pathogenic mutation. Six hundred and thirty-five babies passed the newborn hearing screening, in which 25 babies were identified to carry pathogenic mutations, including 12 heterozygotes (1.9%) for GJB2 235delC, eight heterozygotes (1.3%) for SLC26A4 IVS7-2A>G, one heterozygote (0.2%) for p.R409H, two homozygotes (0.3%) for m.1494C>T, and two homozygotes (0.3%) for m.1555A>G. Conclusion. Newborn genetic screening through the umbilical cord blood for common deafness-associated mutations may identify carriers sensitive to aminoglycoside antibiotic, and can effectively prevent or delay hearing loss occurs.