High-Purity Carbon Dots Prepared by Modulating Morphology of Carbon Nano-Crystals: In Vitro and In Vivo Multi-Color Bioimaging

Feng Huo,Yuran Tang,Yuhang Liu,Chao Tan,Lin Chang,Zakaria Mirza,Wei Zhang 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.15 No.01

Due to the unique optical properties and excellent biological applications, carbon-based luminescent materials have become a research hotspot in recent years. In this paper, we report a synthesis method under mild condition, in which Carbon NanoCrystals (CNCs) were first prepared, and then high-purity multi-color carbon dots (HPMCCDs) were synthesized by modulating crystal morphology. The prepared nonfluorescent CNCs are, respectively, dissolved in a strong polar solvent and a weak polar solvent to prepare HPMCCDs. It exhibits the multi-excitation and multi-emission features (from green to yellow). The high-purity carbon dots (HPCDs) prepared by using this method demonstrate the higher quantum yields (QYs) (53.7%) than that of the carbon dots (CD) by traditional hydrothermal methods with dialysis, and make full use of the atomic economic model. Besides, it shows the unique up-conversion luminescence property (UCLP) at lower wavelength excitation and, which can also be placed for a long time at room temperature without being oxidized or deteriorated. Furthermore, we explored the regulation of polar-chromism mechanism of the CNCs. Finally, the HPMCCDs can be used for multi-color bioimaging in vivo and in vitro and as well as many other potential applications.

New Permeable Structure for Controlling Debris Flows in the Wenjiagou Gully

Yu-feng Liang,Chuan Liang,Hongwei Zhou,Feng-rong Yang,Miao Huo,Jia-wen Zhou 대한토목학회 2018 KSCE JOURNAL OF CIVIL ENGINEERING Vol.22 No.11

Aimed to control debris flows more effectively, we attempt to develop a new structure called a “sloping roof grill dam”, which consists of guidance walls, separation grills and lateral deposit areas. A series of flume tests were performed to verify the function of this new structure, focusing on the trapping efficiency (β ), deceleration efficiency (μ) and coarse-fine sediment separation extents (η) under different conditions of structure and debris flows. Experimental results show that both the trapping and deceleration efficiency increase with a decrease in permeability, whereas the separation extent shown the opposite effect. Multiple regression analysis indicates that β and η are linearly dependent on the permeability, deceleration efficiency and magnitudes of debris flow. In addition, an increase in beam gap can lead to an increase in the impact area downstream for the debris flow after the control of the structure. Finally, a two-level installation of the structure is tested to determine whether there is an enhancement of the debris control, which indicated that although the trapping effect of the two-level structure is considerably greater than that of a single-level structure (2.11 times at maximum), the separation extent of the two-level structure is not distinct and may be even lower.

Inkjet Printed Quantum Dots Color Conversion Layers for Full-color Micro-LED Displays

Feng Qin,Cao Liu,Wenhui Wu,Wenxiang Peng,Sitao Huo,Jiandong Ye,Shulin Gu 대한금속·재료학회 2023 ELECTRONIC MATERIALS LETTERS Vol.19 No.1

With the ever-growing demands for larger size and high resolution displays, Micro-light-emitting diode (Micro-LED) displaywith quantum dots (QDs) fi lm as color conversion layers (CCLs) has become one of the most promising candidates offuture display for its advantages in low power consumption and wide color range. In this study, we report a novel full-colordisplay based on blue Micro LED, which has patterned red and green QDs color conversion (QDCC) layers fabricated byinkjet printing (IJP). A structure of double-layer bank was designed to reduce color deviation, prevent crosstalk, and fl attenthe QDCC layer. By optimizing the thickness of the red/green QDCC layers and the wavelength of blue Micro LEDbacklights, a full-color QDCC-LED display with 228 PPI resolution and size of 1.11-inch was successfully fabricated andshowed superb performance. We not only eff ectively reduced crosstalk, but also improved the color conversion effi ciency ofQDs. In addition, this QDCC-LED display prepared by embedded bonding process shows a color gamut of 107.53% NTSC.

International Digital Design Invitation Exhibition

Boyang Feng,Chen Song,HanwenXU,He Gao,Kai Huo,Kuifang Li,Niu Wei,Shaopeng Han,Tingting Qu,Ting Li,Wang, di,Xu Yeni,Yanlin Xie,Bertrand Planes,Chi-Wook Nho,Jean-benoit Lallemant,Yeon Gyu-Seok,Bettina W 한국콘텐츠학회 2010 ICCC International Digital Design Invitation Exhib Vol.2010 No.12

The Clinical, Molecular, and Mechanistic Basis of RUNX1 Mutations Identified in Hematological Malignancies

Yokota, Asumi,Huo, Li,Lan, Fengli,Wu, Jianqiang,Huang, Gang Korean Society for Molecular and Cellular Biology 2020 Molecules and cells Vol.43 No.2

RUNX1 plays an important role in the regulation of normal hematopoiesis. RUNX1 mutations are frequently found and have been intensively studied in hematological malignancies. Germline mutations in RUNX1 cause familial platelet disorder with predisposition to acute myeloid leukemia (FPD/AML). Somatic mutations of RUNX1 are observed in various types of hematological malignancies, such as AML, acute lymphoblastic leukemia (ALL), myelodysplastic syndromes (MDS), myeloproliferative neoplasm (MPN), chronic myelomonocytic leukemia (CMML), and congenital bone marrow failure (CBMF). Here, we systematically review the clinical and molecular characteristics of RUNX1 mutations, the mechanisms of pathogenesis caused by RUNX1 mutations, and potential therapeutic strategies to target RUNX1-mutated cases of hematological malignancies.

Influence of Perineural Invasion on Survival and Recurrence in Patients with Resected Pancreatic Cancer

Zhang, Jun-Feng,Hua, Rong,Sun, Yong-Wei,Liu, Wei,Huo, Yan-Miao,Liu, De-Jun,Li, Jiao Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.9

Background: Perineural invasion (PNI) has been reported as one of the sources of locoregional recurrence in resected pancreatic cancer (PC). However the impact of PNI in resected pancreatic cancer remains controversial. The purpose of this study was to determine the association between PNI status and clinical outcomes. Methods: Publications were identified which assessed prognostic significance of PNI status in resected pancreatic cancer up to February 2013. A meta-analysis was performed to clarify the association between PNI status and clinical outcomes. Results: A total of 21 studies met the inclusion criteria, covering 4,459 cases. Analysis of these data showed that intrapancreatic PNI was correlated with reduced overall survival only in resected pancreatic ductal adenocarcinoma (PDAC) patients (HR=1.982, 95%CI: 1.526-2.574, p=0.000). Extrapancreatic PNI was correlated with reduced overall survival in all resected pancreatic cancer patients (HR=1.748, 95%CI: 1.372-2.228, p=0.000). Moreover, intrapancreatic PNI status may be associated with tumor recurrence in all resected pancreatic cancer patients (HR=2.714, 95%CI: 1.885-3.906, p=0.000). Conclusion: PNI was an independent and poor prognostic factor in resected PDAC patients. Moreover, intrapancreatic PNI status may be associated with tumor recurrence.

Intermediate State of Consensus Formation Described by the Tri-Molecular Model

Peng Wang,Feng-Chun Pan,Xue-Ling Lin,Xu-Ming Wang,Jie Huo 한국물리학회 2019 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.75 No.2

Consensuses are essential for a society to run well. The description of consensuses formation is a hot spot for interdisciplinary study. Based on the tri-molecule model, this paper investigated the intermediate state of a group from diffidence to confidence. The model emphasizes the different influences from the internal and the external environments. The former, for one individual, refers to collisions with the others in the group while the latter refers to impacts from the outside of the group. The investigation reveals three variation modes for the intermediate state under different transition ratios and different diffusion modes of the individuals. One variation mode is stable, and the others are unstable. The stable transition mode appears under the condition that the influence from the external environment is stronger than that from the internal environment, which may be realistically observable. This implies that the formation of social consensuses needs some strong external actions, such as advocating, publicizing, training and educating, conducted by the government and others.

Verification of OpenMC for fast reactor physics analysis with China experimental fast reactor start-up tests

Guo Hui,Huo Xingkai,Feng Kuaiyuan,Gu Hanyang 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.10

High-fidelity nuclear data libraries and neutronics simulation tools are essential for the development of fast reactors. The IAEA coordinated research project on “Neutronics Benchmark of CEFR Start-Up Tests” offers valuable data for the qualification of nuclear data libraries and neutronics codes. This paper focuses on the verification and validation of the CEFR start-up modelling using OpenMC Monte-Carlo code against the experimental measurements. The OpenMC simulation results agree well with the measurements in criticality, control rod worth, sodium void reactivity, temperature reactivity, subassembly swap reactivity, and reaction distribution. In feedback coefficient evaluations, an additional state method shows high consistency with lower uncertainty. Among 122 relative errors in the benchmark of the distribution of nuclear reaction, 104 errors are less than 10% and 84 errors are less than 5%. The results demonstrate the high reliability of OpenMC for its application in fast reactor simulations. In the companion paper, the influence of cross-section libraries is investigated using neutronics modelling in this paper

Cordyceps militaris fungus mediated Zinc Oxide nanoparticles for the photocatalytic degradation of Methylene blue dye

Li, Jin Feng,Rupa, Esrat Jahan,Hurh, Joon,Huo, Yue,Chen, Ling,Han, Yaxi,Ahn, Jong chan,Park, Jin Kyu,Lee, Hyun A.,Mathiyalagan, Ramya,Yang, Deok-Chun Elsevier 2019 Optik Vol.183 No.-

<P><B>Abstract</B></P> <P>Zinc Oxide nanoparticles were synthesized via co precipitation methods from <I>Cordyceps militaris</I> fungus. In this method zinc nitrate hex- hydrate were used as a precursor. The Synthesized nanoparticles were characterized through different analytical method for identification of morphology, size, crystallinity and also purity. The nanoparticles gave highest peak at 350 in Uv–vis spectroscopy which confirmed the formation of <I>Cordyceps</I> zinc oxide nanoparticles. The Field emission transmission electron microscopy (FE-TEM) analyzed the morphology, purity and elemental distribution of the nanoparticles. The X-ray powder diffraction (XRD) study explored the size is about 10.15 nm. Finally, the functional group of plant and nanoparticles were identified using FT-IR analyzer. The <I>Cordyceps militaris</I> zinc oxide nanoparticles have ability to degrade hazardous dye Methylene blue about 97% in the presence of Uv-radiation. So this study emphasizes that the <I>Cordyceps militaris</I> zinc oxide nanoparticles can be the best photo catalyst for the safety of our environment from dangerous water pollution.</P>

Fabrication and Interface Structural Behavior of Mg/Al Thickness-Oriented Bonding Sheet via Direct Extrusion

Lei Gao,Feng Li,Ye Wang,Xing Mao Xiao,Peng Da Huo 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.8

Solid-state bonding of heterogeneous materials is one of the effective ways to achieve light weight. An extrusion formingprocess for Mg/Al thickness-oriented bonding sheet was carried out. Due to triaxial compressive stress in the extrusion container,the AZ31 and AA6061 billets were deformed and the bonding and forming of Mg/Al thickness-oriented sheet can berealized by this method. The observation results of the bonding position by using XRD, SEM and EDS showed that: at theforming temperature with 360–420 °C, it had a good bonding interface, and the width of the transition layer increased withthe increase of the forming temperature. The presence of brittle intermetallic compounds in the transition layer indicated thatmetallurgical bonding had occurred at the interface. Considering all factors comprehensively, when the forming temperaturewas 390 °C, the bonding quality was appropriate. Its tensile-shear strength was 42 MPa, the width of the interface transitionlayer was about 10 μm, and the microhardness was about 164.3 HV. This method provided scientific guidance and technicalreserves for green forming of Mg/Al sheets.