신경회로망을 이용한 이면비드 폭 예측에 관한 연구

정재원,김일수,박창언,김학형,서주환,김인주,심지연 한국공작기계학회 2008 한국공작기계학회 춘계학술대회논문집 Vol.2008 No.-

The development of robotic welding process is a very complex assignment because the system is affected by a number of process parameters which are very difficult to determine or predict in practice. The full automation welding has not yet been achieved partly because the mathematical model for the process parameters of a given welding task is not fully understood and quantified. Several mathematical models to control welding quality, Productivity, micro structure and weld properties in arc welding processed have been studied. However, it is not an easy task to apply them to the various practical situations because the relationship between the process parameters and the bead geometry is non-linear and also they are usually dependent on specific experimental result. Practically, it is difficult, but important to know how to establish a mathematical model that can predict the result of the actual welding process and how to select the optimum welding condition under a certain constraint. In this paper, an attempt has been made to develop an neural network model to predict the back-bead width as a function of key process parameters in the GMA (Gas Metal Arc) welding and to compare the developed models with the experimental results

교육연극을 위한 극본 자료 개발

김재수,최도순,정경미,백혜경,조은주,김선진 光州敎育大學校 初等敎育硏究所 2002 初等敎育硏究 Vol.17 No.-

When teachers are in need of the script of a play during school hours, Teachers could make a drama out of an interesting story. And by doing learning activities that students are also able to replace an interesting story with a drama, Students are able to understand create an original story. For this purposes, this study explains the methods that teachers make a story. And we make a drama out of a story which is korean language textbook for the seventh curriculum (one∼for grade). And we have teachers to use it lesson.

가상대장내시경검사를 이용해 진단한 장관포상기종 1예

함주호 ( Joo Ho Ham ),김태호 ( Tae Ho Kim ),한석원 ( Sok Won Han ),조근종 ( Keun Jong Cho ),최선욱 ( Son Ook Choi ),백정선 ( Jung Sun Pack ),양성은 ( Seong Eun Yang ),김상희 ( Sang Hee Kim ),양승아 ( Seung Ah Yang ),이윤정 ( Yune 대한소화기학회 2007 대한소화기학회지 Vol.50 No.5

Pneumatosis cystoides intestinalis (PCI) is a rare condition characterized by multiple gas filled cysts in the intestinal wall. The diagnosis of PCI is usually made by colonoscopy, histology, or radiologic findings. We report a case of PCI in a 35-year-old man. The patient initially complained of watery diarrhea and abdominal bloating for 2 weeks. Simple abdominal X-ray demonstrated numerous, small, round, air densities on the right upper abdomen along the ascending and proximal transverse colon. Colonoscopy revealed numerous, 5-20 mm sized, sessile poly-poid, balloon-like distended, protruding subepithelial masses covered with normal colonic mucosa from cecum to proximal transverse colon. We performed a CT colonoscopy and confirmed PCI with multiple air-filled cystic masses along the colonic wall from cecum to proximal transverse colon. The patient was treated with antibiotics and oxygen inhalation for 2 weeks. Follow-up CT colonoscopy revealed marked regression in the number and size of the air-filled cystic masses. Herein, we report the first case of the PCI in Korea diagnosed by CT colonoscopy. Follow-up evaluation with CT colonoscopy was performed after the treatment of the PCI. CT colonoscopy is a useful non-invasive diagnostic tool for the diagnosis of pneumatosis cystoides intestinalis. (Korean J Gastroenterol 2007;50:334-339)

대장암에서 Cdx2 단백발현의 의의

백종해 ( Jong Hae Pack ),김태동 ( Tae Dong Kim ),오현아 ( Heun Ah Oh ),이은주 ( Eun Joo Lee ),김준환 ( Jun Whan Kim ),장병익 ( Byung Ik Jang ),김태년 ( Tae Nyeun Kim ),정문관 ( Moon Kwan Jung ),배영경 ( Young Kyung Bae ) 대한소화기학회 2005 대한소화기학회지 Vol.46 No.3

목적: Cdx2는 최근에 알려진 유전자로 intestine-specific transcription factor를 암호화하고 인체에서는 소장과 대장의 상피 세포에서 특이적으로 발현되며 장상피세포의 성장과 분화에 중요한 역할을 한다. 원발 대장암에서 Cdx2 단백발현 이상이 보고되었고, 종양억제 유전자로 작용할 것이라는 연구 결과가 있다. 이에 저자는 침윤 대장암 조직에서 Cdx2 단백발현 정도를 측정하여 한국인 대장암에서 Cdx2 단백발현 소실의 빈도를 알아보고, Cdx2 단백발현 유무와 대장암의 임상병리 특징과의 관련성을 분석함으로써, Cdx2 발현정도가 대장암 발생 및 종양의 표현형 결정에 어떤 영향을 미치는지 알아보고자 하였다. 대상 및 방법: 영남대학교 의과대학 부속병원에서 대장암으로 수술한 환자 420명의 종양 조직 및 유방암, 정상 대장, 간, 위, 폐, 신장, 난소 조직을 대조군으로 하여 면역조직화학염색을 이용하여 Cdx2 단백 발현을 조사하였다. 결과: 환자의 90.5% (380/420)에서 Cdx2 단백발현이 관찰되었으며, 이 중 83% (349/420)는 강양성, 7.5% (31/420)는 약양성이었다. 대조군으로 사용한 145개 유방암 조직 모두에서 Cdx2 단백발현은 관찰되지 않았으며, 정상 간, 신장, 폐, 난소 조직도 모두 Cdx2 면역조직화학 염색에 음성이었다. 정상 위 점막에서는 장형화생을 동반한 부위에 국한되어 Cdx2 발현이 관찰되었다. 종양 인접 부위에 존재하거나 대조군으로 사용한 정상 대장 점막조직에서는 100%에서 Cdx2 단백발현이 관찰되었다. 임상병리 특징과 Cdx2 단백발현과의 관계는 종양의 침윤이 깊을수록(p<0.05), 림프절 전이가 있는 경우(p<0.001), 원격전이가 있는 경우 그리고 조직분화도가 낮을수록(p<0.001) Cdx2 단백발현이 의미 있게 감소하였다. 결론: 종양의 악성도와 Cdx2 단백발현 소실과는 밀접한 관련성이 있으며, 따라서 Cdx2가 대장 및 직장암의 예후인자로 유용한 역할을 할 수 있을 것이다. 또한 Cdx2 단백은 장세포 기원의 암종에 매우 특이한 표지자로서, 전이 암종의 원발 장기 규명에 이용할 수 있을 것으로 생각한다. Background/Aims: The caudal-related homeobox transcription factor, Cdx2, plays an important role in proliferation and differentiation of intestinal epithelial cells. Its expression is confined to normal and neoplastic intestinal epithelium. We evaluated Cdx2 expression in advanced colorectal cancers to determine the correlation between Cdx2 expression and clinicopathologic characteristics. Methods: Four hundreds twenty consecutive colorectal cancers were included in the study. Cdx2 expression was investigated by immunohistochemistry using tissue microarrays constructed from surgically resected specimens. 145 invasive breast cancers, normal tissues from gastric mucosa, liver, lung, kidney and ovary were used as control. Nuclear staining was considered to be positive and the result was divided into 3 categories. Results: In the colorectal cancers, Cdx2 was expressed in 380 of 420 (90.5%) cases, and 349 of 380 (83%) cases showed strong and diffuse staining and 31 of 420 (7.5%) cases showed weakly positive staining. Forty patients (9.5%) of colorectal cancer were negative for Cdx2. All of the invasive breast cancers and all non-neoplastic control tissues except the regions of intestinal metaplasia in gastric mucosa, which showed strong Cdx2 expression, were negative for Cdx2. Loss of Cdx2 expression was observed more frequently in cases with deeper invasion (p<0.05), lymph node metastasis (p<0.05), poor histologic differentiation (p<0.001), and distant metastasis (p<0.05). Conclusions: Cdx2 could be a highly sensitive marker to detect metastasis from intestine and might be useful as a novel prognostic marker in colorectal cancers. (Korean J Gastroenterol 2005;46:204-210)

Bioconversion of crude glycerol by using electrochemically active strain, Klebsiella Pneumoniae L17 with ZVI

Da Seul KONG,Changman KIM,Eun Joo PACK,Jung Rae KIM 한국생물공학회 2021 한국생물공학회 학술대회 Vol.2021 No.10

1,3-Propandiol is widely used as adhesives, laminates and food additives for three carbon sources. Sustainable and non-toxic regeneration of NADH is critical for efficient production of 1,3-PDO. Zero-Valent Iron(ZVI) can provide reducing equivalent for 1,3-PDO synthesis from glycerol as an electronic donor. Klebsiella Pneumaniae has 1,3-PDO production pathway from glycerol, and has been extensively investigated as exoelectrogens. In this study, we attempt to produce 1,3-PDO from un-purified crude glycerol produced from biodiesel process by using an electrochemically active strain, K. pneumoniae L17. The results showed significant increase of 1,3-PDO production using the ZVI. It seems that unidentified component in a crude glycerol may bring synergetic effects for both cell biomass and 1,3-PDO production. These results implicate that ZVI can regulate the bioconversion of electroactive strain such as L17, therefore improve crude glycerol conversion into value-added platform chemicals.

GPS-Van을 이용한 도로기반의 수치지도 수정 가능성 검증

정주권(Jeong Ju Kwon),주영은(Joo Young Eun),최종현(Choi Jong Hyun),박수영(Pack Su Young) 대한공간정보학회 2004 한국지형공간정보학회 학술대회 Vol.2004 No.10

칼라(Zantedeschia albomaculata spp.)의 조직배양시 식물체의 분화에 미치는 생장 조절 물질의 영향

장혜숙(Hea-Sook Chang),한은주(Eun-Joo Han),백기엽(Kee-Yoeup Pack) 한국원예학회 2000 원예과학기술지 Vol.18 No.5

요추 경막외 마취에서 카테테르 삽입 방향과 지각차단범위

한종인,김종학,이춘희,이귀용,김치효,정락경,백은주 대한마취과학회 1997 Korean Journal of Anesthesiology Vol.33 No.2

Background : Endoscopic urologic surgery including transurethral resection of prostate(TURP) requires adequate sacral analgesia for insertion of resectoscope. But epidurally administered local anesthetic does not produce anesthetic effects uniformly. Failure to completely block S1 during epidural anesthesia because of the large size of nerve root has been noted. The purpose of this study to compare the relation between catheter direction and sensory anesthesia. Methods : Thirty patients scheduled for endoscopic urologic surgery were enrolled. The epidural catheter was inserted at L3-4 using a standard 18 gauge Tuohy needle. In group A(n=15), the Tuohy needle with bevel pointed in a cephalad direction during catheter insertion. In group B(n=15), it pointed caudally. And the catheter was introduced 3 cm into the epidural space. After test dose, 2% lidocaine 5 cc, 0.5% bupivacaine 5 cc and 2% lidocaine 3 cc were administered with fractionate dose through it. The extent of the sensory anesthesia to loss of cold sensation and pin prick test was measured every 5minute for 30 minutes. Results : Analgesia spread to loss of cold sensation and pin prick test was no significant statistical difference between the two groups. In 15 minutes after injection of surgical dose, complete blockade in L5, S1 dermatome was present in both groups. Conclusion : Our results conclude that epidural catheter direction is not significantly influence the epidural anesthetic spread including sacral area in continuous lumbar epidural anesthesia in elderly patients. (Korean J Anesthesiol 1997; 33: 291∼296)