농약살포자 혈중 콜린에스테라제 활성도의 변화 및 농약성분

신동천,이순영,정상혁,원종욱,박종세,박송자 大韓産業醫學會 1994 대한직업환경의학회지 Vol.6 No.2

In order to ascertain the status of health damage among Korean farmers who spray pesticides regularly in summer, blood and urine samples were collected for 88 volunteers during July to September in 1990. Serum cholinesterase activity, parent compounds of pesticides in blood and urine, SGOT, SGPT, blood pressure, pulse rate were measured. The results were as follows; 1. Mean cholinesterase activity after spraying pesticides was significantly lower than that before spraying. While proportion of abnormal cholinesterase activity(<1990 U/L) group was 2.3% before spraying pesticides, the proportion of the group after spraying was 22.8%. 2. Cholinesterase activity were decreased over 50% in 14.7% of the subjects who can be classified into poisoning group 3. While pulse rate and blood pressure were slightly increased in poisoning group, those were significantly decreased in non-poisoning group. 4. Consecutive spraying of pesticide caused further reduction of cholinesterase activity. 5. Five parent compounds of pesticides frequently used during summer farming were analyzed using 106 blood samples. IBP in one sample and Isoprothiolane in four samples were detected. No parent compounds were detected in urine samples.

항공사의 외국인 소유

신동춘 한국항공우주법학회 1993 한국항공우주정책·법학회지 Vol.5 No.-

Taxol 합성에 관한 연구 Ⅰ : O-(tert-Butyldiphenylsily1)-cis-5-methyl-4-hepten-6-yn-1-ol의 합성 Synthesis of O-(tert-Butyldiphenylsily1)-cis-5-methyl-4-hepten-6-yn-1-ol

신동수,박두천,주우홍,김형국 國立 昌原大學校 基礎科學硏究所 1994 基礎科學硏究所論文集 Vol.6 No.-

O-(tert-Butyldiphenylsily1)-cis-5-methyl-4-hepten-6-yn-1-ol, an intermediate in the synthesis of taxol, was efficiently synthesized from 3-methyl-2-penten-4-yn-1-ol by sequential alcohol/bromide interchange [NBS, PPh_(3), CH_(2)Cl_(2), -30℃, 82%], displacement with the lithium salt of tert-butylacetate [LDA, THF, -78 to 23℃, 84%], LAH reduction, and silylation [tBuPhSiCl, imidazole, CH_(2)Cl_(2), 45℃, 88%].

農村現場實習에 關한 意見調査分析

全太甲,愼鏞仁,崔在律,金銅淵 全南大學校 農漁村開發硏究所 1975 農業科學技術硏究 Vol.10 No.-

The Survey was conducted to find the present situation and to recommend the effective ways at the Work Experience Progran in the Colleges of Agriculture. A series of responses for the researcher developed questionnaires were obtained from the 370 students and 77 experience program supervisors and farmers. Another interviws were made with the administrators or professors in the 24 agricultural colleges for abtaining the informations, ideas and recommendations. According to this research, we found that we could imporve the Work Experience program strenuously but not now. Most experience program supervisors and the farmers suggested the most effective way to improve the program as follows ① Students should be motivated for active participation.② Work Experience Program must be fitted to their profession and Department. ③ It should be conducted under the scrutinized and careful plan. ④ Evaluation of the program should be improved and supervision of the place supervisors and farmers should be encouraged.

자외선 (UVB) 노출 증가에 대한 피부암 위해도 예측 모델의 적용

신동천,이종태,정용,강나경,양지연 한국환경독성학회 1996 환경독성보건학회지 Vol.11 No.1

A decrease in stratospheric ozone probably caused by chloroflurocarbons (CFCs) emissions, has been observed large parts of the globe. It is generally accepted that if ozone levels in the stratosphere are depleted, greater amounts of shortwave ultraviolet radiation-B (UVB) will reach the earth's surface, resulting in increased incidence of nonmelanoma skin cancer. In this study, we evaluated several mathematical models, such as a power and an exponential model, and a geometric model considering the surface area of a human body part and ages for the prediction of skin cancer incidence caused by exposure to the UVB radiation. These models basically estimated the risk of skin cancer based on those measurements of the local ozone in stratosphere and UVB. Both were measured at a part of Seoul with a Dobson ozone spectrometer and Robertson-Berger UV Biometer for 1995. As a result, we calculated the point estimation applying a biological amplification factor (BAF), UVB radiation and other factors. We used a Monte-Carlo simulation technique with assumption on the distribution of each considered factor. The sensitivity analysis of model by there components conducted using Gaussian sensitivity method. The annual integral of UVB radiation was 2275 MED (minimal erythema dose)/yr. Also, an estimate of the annual amount of UVB reaching the earth's surface at a korea's latitude and altitude was 3328 MED/yr. The values of the radiation amplification factor (RAF) were ranged from 0.9 to 1.5 in Seoul. To give the effective factors required to model the prediction of skin cancer incidence caused by exposure to the UVB radiation in Korea, we studied the pros and cons of above mentioned models with the application of those parameters measured in Seoul, Korea.

지하수 중 자연방사성물질의 위해성 관리에 대한 고찰

신동천,김예신,문지영,박화성,김진용,박선구 한국환경독성학회 2002 환경독성보건학회지 Vol.17 No.4

At present, the health risks associated with the natural radionuclides of ground water have become a concern as potential social problems. However, there are no regulatory actions or control strategies for such risks. Therefore, we have investigated and discussed the risks and associated management strategies for radionuclides in other countries. US EPA has proposed MCL (300 pCi/L) and AMCL (4,000 pCi/L) for radon, and 30 ppb for uranium, 15 pCi/L for gross-alpha and 5 pCi/L for radium as final MCLs. Also, Canada, WHO and European countries have their inherent management levels. Finally, we suggested several criteria for setting guidelines in our countries including exposure related criteria such as geological distribution, occurrence, exposure probability distribution, exposure population and multimedia exposure assessment, acceptable risk, and cost-benefit analysis. The national-scale exposure and risk assessment, and economic analysis should be conducted for producing and aggregating the representative information on these criteria.

다이옥신 (2, 3, 7, 8-tetrachlorodibenzo-p-dioxin) 의 건강위해성에 대한 고찰 : Review

신동천,안혜원,이종태,정용 한국환경독성학회 1996 환경독성보건학회지 Vol.11 No.2

There are numerous and evidential findings that TCDD (2, 3, 7, 8-tetrachlorodibenzo-p-dioxin, or dioxin) is a potential carcinogen and general toxin in rodents. However, human risk assessment for dioxin exposure has been a topic of debate, owing in part to the large animal interspecies differences in its toxicity. We review dioxin-related reports indicating its toxicity, toxic effects in animal, and human epidemiologic findings. The intent of this paper does not provide a causal inference about chronic human diseases related to dioxin exposure. This summary would give a valuable clue for a researcher to conduct or design a further dioxin-related study.

남북한 경제통합과 산업구조

신동천,이영선,윤덕룡 연세대학교 통일연구원 2001 통일연구 Vol.5 No.1

This paper addresses the problem of how to allocate industries on Korean peninsula after two Koreas are unified.It is asserted in the paper that South Korean capital with advanced technology should be combinedwith North Korean quality labor in order to maximize the benefit from economic cooperation in the short run.In the long run, North Korea's infrastructure should be strengthened and extended with the help of South Korea and other foreign countries to minimize the unification cost and make the unification mutually beneficial.The paper seeks the optimal allocation of industries that allows unified Korea to achieve economic growth and efficient resource allocation.

동종 골수이식 후 만성 이식편대숙주반응 환자에서 발생한 폐렴구균에 의한 수막뇌염 1예

신완식,김병욱,유진홍,김동집,김춘추,박종원,이종욱,김동욱,강문원,김양리 대한감염학회 1993 감염 Vol.25 No.3

Graft-versus-host disease (GVHD) is a frequent complication after bone marrow transplantation. Infectious complications are common in GVHD patients due to defect in cell-mediated immunity. A rare case of S. pneumoniae meningoencephalitis occured in a patient with extensive form of chronic GVHD after allogeneic bone marrow transplantation. He was immediately treated with full dosage of ceftriaxone and ampicillin. He suffered from various complications such as sepsis, acute renal failure, atelectasis, and seizure. Despite of aggressive treatment, he died probably due to renal shutdown and massive subacute cerebral infarction of left cerebral hemisphere. This report showed two unusual and rare features. First, the infection site was CNS rather than respiratory system. Second, the causative organism was S. pneumoniae, which is rare cause of CNS infection in immunocompromised patients.

The Prelude 에 나타난 Wordsworth의 自然觀

申東春 漢陽大學校 人文科學大學 1981 人文論叢 Vol.1 No.-

In the context the of Wordsworthian view of nature refleced in The Prelude, nature reveals itself as an animated being without an impression of rigidity of the fixed obfects of the universe. Therefore it is my opinion that his bearing towards nature should beidentified in order to grasp the implication of the Prelude. To begin with, an intensive analysing of three typical Wordworthian scenes out of its various spots of time such as scenes of 'skating,' 'rowing' and 'bird's nesting,' was attempted. Because his nature is a part of "active Universe," the experimental obser vation of these scenes has brought a remarkable fact to the light that nature and the poet both on the same level, acting and reacting to each other, were on the process of achieving the so-called Wordsworthian ideal. In this process, however, lies one of the most complicated Wordsworthian themes which may cover a considerable scope of Wordworthian studies. On the other hand, it is the the immediate channel to coleridg'es theory of Imagination and Wordsworthian acholars' achievements in the aspect of the Lochean Tradition. Thus habe Geoffrey Hartman, Langbaum, Willey, Baker, Barth and Collingwood arrived at the controversial premise of visionary power and plastic power and plastic power examined ever since the days of Biographia Literaria. The ambiguity involved in the 'mysterious' blending of the sensual perception of nature and the reflective mind has merited another weighty field of depth sturcture, studies by Arthur Koestler, the author of the Act of Creation, Wordsworth's imagination projected in The Prelude was traced to his subconcsiousness. At the end of a general survey of the suggestions by the critics referred to, it was concluded that David Hume's theory of introspection might be most applicable to solve the problem, lessened the ambiguity implied by Wordsworthian imagination. Hume's distinction of 'Impressions' and 'Ideas' may well be located at the ideal interchange of Lochean Empericsm and Kantian Idealism as well as at the closest spot to Wordsworthian insight, the final key to his relation with nature.