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      • 지팡이의 높이가 체중 지지분포에 미치는 영향

        옥준영,김진우,한우석,한재덕,안덕현 한국전문물리치료학회 2000 한국전문물리치료학회지 Vol.7 No.1

        This study investigates the influence of cane length on the weight distribution of the elderly in a standing position. Thirsty participants were evaluated using two different cane lengths based on measurements of distal wrist crease to ground (WC cane), and distance of greater trochanter to ground (GT cane). A limloader was used to determine the weight distribution on the subject. It was found that 6.5% of body weight was supported on a GT cane and 7.7% of body weight supported on a WC cane in a standing position. Results suggests that more weight is distributed on a WC cane than a GT cane in the elderly.

      • KCI등재

        C형 및 S형 단백 결핍에 의한 하지 심부 정맥혈전증

        김향경,조용필,이덕희,안재홍,장혁재,김지수,김용호,한명식 대한혈관외과학회 2002 Vascular Specialist International Vol.18 No.2

        Purpose: Protein C and S deficiencies are frequently described as causes of the hypercoagulable states. The aim of this study was to evaluate the clinical features and prognosis of deep venous thrombosis associated with protein C and/or S deficiencies and to determine an adequate treatment modality for such cases. Method: A total of consecutive 42 patients with deep venous thrombosis of the lower extremity were seen in our hospital between September 2000 and August 2002. Hypercoagulability studies were done before systemic anticoagulation therapy, and the diagnosis of protein C and/or S deficiencies was confirmed if antigenic protein C and/or S levels were less than 60%. Result: Seven patients (16.7%) were diagnosed with deep venous thrombosis associated with protein C and/or S deficiencies. Of these, 5 patients with acute iliofemoral deep venous thrombosis were treated with catheter-directed thrombolysis therapy, and 2 with systemic anticoagulation therapy. There were no major complications or clinically detectable pulmonary emboli. Conclusion: Protein C and/or S deficiencies are one of the common causes of deep venous thrombosis. Considering that patients with deep venous thrombosis and protein C and/or S deficiencies should be treated with life-long anticoagulation for the prevention of recurrence, patients presenting with deep venous thrombosis without evidence of other risk factors should be evaluated for hypercoagulable states.

      • 뿜칠시공에 의한 단면복구재의 시공성 및 공학적 특성에 관한 실험적 연구

        조봉석,김영선,장재봉,김용로,김경덕,김무한 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1

        These days, serious concerns of reinforced concrete have been raised recently over steel-bar corrosion, cracking, the deterioration of durability and structural stress resistance and so on, all due to the effects of exterior factors. Such being the case, in domestic, various repair materials and method systems to keep up with these reinforced concrete deteriorated due to salt damage, carbonation, chemical decay et. developed and applied. However, on-site quality control of various repair materials and method systems isn't achieved desirably because it is depend completely on a men of experience' opinions above all else regardless of various on - site environments. In this background, mock up test with due regard to real on-site environments was performed to secure fundamental data for establishment of desirable on-site quality control. Mock up test using repair mortar analyzed from angles of construction methods, mechanical spraying pressures, W 1M. Construction methods were designed manpower method and spraying method, spraying pressures were designed 32, 42, 52 psi, W/M were designed 14.4, 15.4, 16.4 %. And compressive strength, Chloride ion diffusion coefficient, bond strength, SEM of mock up test specimens were evaluated. In conclusion, we confirmed excellency of mechanical spraying pressures, fined extremely excellency of condition of spraying pressure 42 ps, W/M 14.4% within this study. therefore the results of this study will be useful to provide fundamental data for establishment of desirable on-site quality control.

      • SCIEKCI등재

        Relationship between serum brain natriuretic peptide and heart function in patients with chronic kidney disease

        ( Jae Won Yang ),( Min Soo Kim ),( Jae Seok Kim ),( Jong Myoung Yoo ),( Seung Tae Han ),( Bi Ro Kim ),( Yun Deok Kim ),( Jeong Wook Choi ),( Seung Ok Choi ),( Byoung Geun Han ) 대한내과학회 2008 The Korean Journal of Internal Medicine Vol.23 No.4

        Background/Aims: Brain natriuretic peptide (BNP) levels are known to be elevated in patients with chronic kidney disease (CKD) and normal heart function. Therefore, the present study was performed to examine the effectiveness of BNP level in diagnosing heart failure in patients with CKD and to determine its effects on survival rate and prognosis. Method: A total of 182 patients with CKD who visited the hospital due to dyspnea of NYHA class II were included in the study. BNP levels were measured and echocardiography was performed to divide the subjects into groups with and without heart failure. Their BNP levels, clinical courses, and survival rates were analyzed retrospectively. Results: When BNP level was ≥858.5 pg/mL in CKD patients, heart failure could be diagnosed with sensitivity and specificity of 77% and 72%, respectively. Survival rate of the group with BNP levels of ≥858.8 pg/mL was significantly lower than that of the group with BNP level below this threshold (p=0.012) and multivariate analysis showed that BNP level, age, and sex affected survival rate in the group with BNP level ≥858.8 pg/mL. Conclusions: BNP levels of patients with CKD showed a positive correlation with creatinine levels, and the critical point of BNP level for diagnosis of heart failure was 858.5 pg/mL. As the survival rate in patients with BNP level above the critical point was significantly low, this level was a useful indicator for predicting their prognosis. Care should be taken in interpreting BNP level because patients with stage 5 CKD may show a high concentration of BNP without heart failure.

      • A Case of Small Bowel Adenocarcinoma in Patient Who Had Duodenojejunostomy

        ( Deok-jae Han ),( Eung-koo Lee ),( Kiwon Shin ),( Bong Han Kong ),( Sung Hoon Jung ),( Jung Hwan Oh ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1

        Small bowel malignancies are very rare and account for 0.1-0.3% of all malignancies, and 0.35% in South Korea. Primary adenocarcinoma is the most common subtype makes up 35.8% of all small bowel malignancies. According to Korea central cancer registry, 535 new cases of small bowel malignancies occurred for 2010. The clinical presentation and diagnosis of small bowel adenocarcinoma are usually delayed because the disease is not amenable to endoscopic examination, and especially it located distal to duodenum. Furthermore, incidence rate of such patient with anatomical changes in bowel is yet unknown. We authors report a case of patient with small bowel adenocarcinoma who had previously duodenojejunostomy. A 78-year old female was admitted to our hospital suffering from sustained nausea and vomiting for 2 months. Her medical history included duodenojejunostomy as treatment for small bowel mass 20 years ago, appendectomy, hypertension and type 2 diabetes mellitus. She took abdomen computed tomography (CT) scan 7 months prior to admission, showed fatty liver and renal cysts only. Abdomen CT scan at admission, however, indicated jejunal mass with distended proximal bowel loops and metastatic lymphadenopathies (LAPs) on mesentery. Small bowel series revealed near complete obstruction of jejunum with apple core like mass and ulceration. We couldn’t examine esophagogastroduodenoscopy (EGD) or capsule endoscopy since anatomical deterioration which noted in previous EGD, instead small bowel series was done for diagnosis. Mass was resided in proximal jejunum and metastatic LAPs were found in proximal mesentery intraoperatively. Small bowel segmental resection including jejunal mass with mesenteric lymph node dissection was done. Jejunal mass was diagnosed as moderate to poorly differentiated adenocarcinoma on pathology, and so as dissected lymph node. On postoperative 2 months, no recurrent malignancy is found in follow up abdomen CT scan. Her symptoms of nausea and vomiting also subsided and have good performance, either. Allude to this case, clinicians may take note of small bowel malignancy even with nonspecific symptoms if they persist or if patient had anatomical change in bowel.

      • Poster Session : PS 1424 ; Hemato-Oncology(Oncology) : Successful Treatment of Intracranial Germ Cell Tumor: Report of Unusual Two Cases with Literature Review

        ( Jae Seok Lee ),( Yun Hwa Jung ),( In Sook Woo ),( Young Yun Cho ),( Yun Duk Jung ),( Deok Jae Han ),( Chi Wha Han ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Primary intracranial germ cell tumor (GCT) is a rare subset of intracranial tumor. They are known to occur primarily in 2nd and 3rd decades of life and arise from midline structure especially pineal gland or suprasellar region due to aberrant migration during embryogenesis. Although intracranial GCT is sensitive to treatment, high recurrence rate, treatment related long term complications, unusual cases including bifocal germinoma or nongerminomaous germ cell tumor (NGGCT) make treatment complicated. Moreover, because of locational feature, hydrocephalus and visual field defect, functional disturbance of pituitary gland can occur and require attention. Treatment primarily relys on chemotherapy and radiation therapy but there is difference between germinoma and NGGCT. Here, we present two cases of intracranial GCT which are relatively uncommon. One case was bifocal intracranial germinoma and the other was intracranial choriocarcinoma. Both cases were treated with neoadjuvant chemotherapy (4 cycles of ifosfamide, carboplatin and etoposide combination chemotherapy) followed by reduced field radiation therapy without significant treatment related complication. Further, we performed a PUBMED search to investigate appropriate treatment strategy of unusual subtype of intracranial germ cell tumor.

      • The Korean Association of lnternal Medicine : Poster Session ; PS 1339 : Nephrology ; A Case of Severe Arterial Steal Syndrome Developing after Percutaneous Angioplasty of Arteriovenous fistula Stenosis

        ( Deok Jae Han ),( Su Jin Choi ),( Young Soo Kim ),( Sun Ae Yoon ),( Young Ok Kim ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Arterial steal syndrome is rare but a serious complication which causes retrograde fi ow disruption distal to arteriovenous fi stula (AVF) because of excessive blood fi ow through the AVF. A 65-year-old woman with diabetic end stage renal disease on hemodialysis was admitted with complaint of coldness and pain in the right hand. AVF stenosis had been developed 6 months after the upper arm AVF operation. These manifestations developed 2 days after successful radiologic intervention and became worsened to ulceration, and aggravated especially during dialysis. fistulogram revealed arteriovenous anastomosis site was patent but blood fi ow toward forearm was severely decreased. Dialysis access steal syndrome developing after percutaneous angioplasty of arteriovenous fi stula stenosis was suspected, and ligation of the arteriovenous fi stula was performed successfully. After ligation of the arteriovenous fi stula, hand pain and ulceration were resolved. To the best of our knowledge, it is fi rst case of arterial steal syndrome after angioplasty.

      • KCI등재

        Comparison of Clinical Severity of Congenital Muscular Torticollis Based on the Method of Child Birth

        Seung Jae Lee,임신영,Jae Deok Han,Han Byul Lee,Jee Hyun Hwang,Se Yon Kim,박명철 대한재활의학회 2011 Annals of Rehabilitation Medicine Vol.35 No.5

        Objective To compare the clinical severity of congenital muscular torticollis (CMT) based on the method of child birth. Method Children diagnosed with CMT and who were < 6-years-of-age at the time of their first visit at the Center for Torticollis, Ajou Medical Center, were included in this study. The medical records were retrospectively reviewed with reference to the method of child birth and the clinical severity of CMT. The clinical severity of CMT was determined either by whether stretching exercises were needed for the children <6-month-of-age or whether surgical release was required for the children ≥6-months-of-age at the time of the first visit. Results One hundred seventy eight subjects with CMT were enrolled. Th ere was no signifi cant difference in the rate of surgical release according to the method of child birth. For 132 patients <6-month-of-age there was also no signifi cant difference in the rate of stretching exercises. Conclusion Th ere was no signifi cant diff erence in the clinical severity of CMT based on the method of child birth. This fi nding suggests that prenatal factors alone could be a cause of CMT and that the clinical severity of CMT in children delivered by Cesarean section is not different when compared with the severity of CMT in children born through vaginal delivery.

      • Src Is a Prime Target Inhibited by <i> Celtis choseniana</i> Methanol Extract in Its Anti-Inflammatory Action

        Kim, Han Gyung,Choi, Subin,Lee, Jongsung,Hong, Yo Han,Jeong, Deok,Yoon, Keejung,Yoon, Deok Hyo,Sung, Gi-Ho,Lee, Seungihm,Hong, Suntaek,Yi, Young-Su,Kim, Jong-Hoon,Cho, Jae Youl Hindawi 2018 Evidence-based Complementary and Alternative Medic Vol.2018 No.-

        <P><I>Celtis choseniana</I> is the traditional plant used at Korea as a herbal medicine to ameliorate inflammatory responses. Although<I> Celtis choseniana</I> has been traditionally used as a herbal medicine at Korea, no systemic research has been conducted on its anti-inflammatory activity. Therefore, the present study explored an anti-inflammatory effect and its underlying molecular mechanism using<I> Celtis choseniana </I>methanol extract (Cc-ME) in macrophage-mediated inflammatory responses.<I> In vitro</I> anti-inflammatory activity of Cc-ME was evaluated using RAW264.7 cells and peritoneal macrophages stimulated by lipopolysaccharide (LPS), pam3CSK4 (Pam3), or poly(I:C).<I> In vivo</I> anti-inflammatory activity of Cc-ME was investigated using acute inflammatory disease mouse models, such as LPS-induced peritonitis and HCl/EtOH-induced gastritis. The molecular mechanism of Cc-ME-mediated anti-inflammatory activity was examined by Western blot analysis and immunoprecipitation using whole cell and nuclear fraction prepared from the LPS-stimulated RAW264.7 cells and HEK293 cells. Cc-ME inhibited NO production and mRNA expression of inducible nitric oxide synthase (iNOS), cyclooxygenase (COX-2), and tumor necrosis factor-alpha (TNF-<I>α</I>) in the RAW264.7 cells and peritoneal macrophages induced by LPS, pam3, or poly(I:C) without cytotoxicity. High-performance liquid chromatography (HPLC) analysis showed that Cc-ME contained anti-inflammatory flavonoids quercetin, luteolin, and kaempferol. Among those, the content of luteolin, which showed an inhibitory effect on NO production, was highest. Cc-ME suppressed the NF-<I>κ</I>B signaling pathway by targeting Src and interrupting molecular interactions between Src and p85, its downstream kinase. Moreover, Cc-ME ameliorated the morphological finding of peritonitis and gastritis in the mouse disease models. Therefore, these results suggest that Cc-ME exerted<I> in vitro</I> and<I> in vivo</I> anti-inflammatory activity in LPS-stimulated macrophages and mouse models of acute inflammatory diseases. This anti-inflammatory activity of Cc-ME was dominantly mediated by targeting Src in NF-<I>κ</I>B signaling pathway during macrophage-mediated inflammatory responses.</P>

      • KCI등재

        비영리점포의 수익성향상을 위한 고객만족과 고객충성도에 미치는 영향요인

        최덕재 ( Deok Jae Choi ),정기한 ( Ki Han Chung ),신재익 ( Jae Ik Shin ) 한국생산성학회 2011 生産性論集 Vol.25 No.3

        The purpose of this study is to investigate the relationship among store image, charity image, customer orientation, customer satisfaction, and customer loyalty in a non-profit store and to provide the implications of marketing strategies to improve its management performance for survival and sustainable growth. The results of data analysis show that store image, charity image, and customer orientation affect positively customer satisfaction and customer loyalty in a non-profit store. Also, customer satisfaction affects positively customer loyalty. The implications mean that a non-profit store can survive and grow through providing high quality of products and customer service and building positive store image and charity image which lead to higher customer satisfaction and loyalty as like profit organization does. The result also propose NPOs to develop marketing communication strategies to promote NPOs` roles such as social warfare, recycling of resources, consideration of the poverty.

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