QoS-Based and Network-Aware Web Service Composition across Cloud Datacenters

( Dandan Wang ),( Yang Yang ),( Zhenqiang Mi ) 한국인터넷정보학회 2015 KSII Transactions on Internet and Information Syst Vol.9 No.3

With the development of cloud computing, more and more Web services are deployed on geo-distributed datacenters and are offered to cloud users all over the world. Through service composition technologies, these independent fine-grain services can be integrated to value-added coarse-grain services. During the composition, a number of Web services may provide the same function but differ in performance. In addition, the distribution of cloud datacenters presents a geographically dispersive manner, which elevates the impact of the network on the QoS of composite services. So it is important to select an optimal composition path in terms of QoS when many functionally equivalent services are available. To achieve this objective, we first present a graph model that takes both QoS of Web services and QoS of network into consideration. Then, a novel approach aiming at selecting the optimal composition path that fulfills the user`s end-to-end QoS requirements is provided. We evaluate our approach through simulation and compare our method with existing solutions. Results show that our approach significantly outperforms existing solutions in terms of optimality and scalability.

QoS and SLA Aware Web Service Composition in Cloud Environment

( Dandan Wang ),( Hao Ding ),( Yang Yang ),( Zhenqiang Mi ),( Li Liu ),( Zenggang Xiong ) 한국인터넷정보학회 2016 KSII Transactions on Internet and Information Syst Vol.10 No.12

As a service-oriented paradigm, web service composition has obtained great attention from both academia and industry, especially in the area of cloud service. Nowadays more and more web services providing the same function but different in QoS are available in cloud, so an important mission of service composition strategy is to select the optimal composition solution according to QoS. Furthermore, the selected composition solution should satisfy the service level agreement (SLA) which defines users` request for the performance of composite service, such as price and response time. A composite service is feasible only if its QoS satisfies user`s request. In order to obtain composite service with the optimal QoS and avoid SLA violations simultaneously, in this paper we first propose a QoS evaluation method which takes the SLA satisfaction into account. Then we design a service selection algorithm based on our QoS evaluation method. At last, we put forward a parallel running strategy for the proposed selection algorithm. The simulation results show that our approach outperforms existing approaches in terms of solutions` optimality and feasibility. Through our running strategy, the computation time can be reduced to a large extent.

QoS and SLA Aware Web Service Composition in Cloud Environment

Wang, Dandan,Ding, Hao,Yang, Yang,Mi, Zhenqiang,Liu, Li,Xiong, Zenggang Korean Society for Internet Information 2016 KSII Transactions on Internet and Information Syst Vol.10 No.12

As a service-oriented paradigm, web service composition has obtained great attention from both academia and industry, especially in the area of cloud service. Nowadays more and more web services providing the same function but different in QoS are available in cloud, so an important mission of service composition strategy is to select the optimal composition solution according to QoS. Furthermore, the selected composition solution should satisfy the service level agreement (SLA) which defines users' request for the performance of composite service, such as price and response time. A composite service is feasible only if its QoS satisfies user's request. In order to obtain composite service with the optimal QoS and avoid SLA violations simultaneously, in this paper we first propose a QoS evaluation method which takes the SLA satisfaction into account. Then we design a service selection algorithm based on our QoS evaluation method. At last, we put forward a parallel running strategy for the proposed selection algorithm. The simulation results show that our approach outperforms existing approaches in terms of solutions' optimality and feasibility. Through our running strategy, the computation time can be reduced to a large extent.

Bone Morphogenetic Protein 9 Overexpression Reduces Osteosarcoma Cell Migration and Invasion

Zilan Lv,Ya-guang Weng,Dandan Yang,Jie Li,Min Hu,Min Luo,Xiaoqin Zhan,Peipei Song,Chen Liu,Huili Bai,Baolin Li,Yang Yang,Yingying Chen,Qiong Shi 한국분자세포생물학회 2013 Molecules and cells Vol.36 No.2

Transforming growth factor- (TGF-) is known to pro-mote tumor migration and invasion. Bone morphogenetic proteins (BMPs) are members of the TGF- family expressed in a variety of human carcinoma cell lines. The role of bone morphogenetic protein 9 (BMP9), the most powerful osteogenic factor, in osteosarcoma (OS) progression has not been fully clarified. The expression of BMP9 and its receptors in OS cell lines was analyzed by RT-PCR. We found that BMP9 and its receptors were expressed in OS cell lines. We further investigated the influence of BMP9 on the biological behaviors of OS cells. BMP9 overexpression in the OS cell lines 143B and MG63 inhibited in vitro cell migration and invasion. We further investigated the ex-pression of a panel of cancer-related genes and found that BMP9 overexpression increased the phosphorylation of Smad1/5/8 proteins, increased the expression of ID1, and reduced the expression and activity of matrix metalloproteinase 9 (MMP9) in OS cells. BMP9 silencing induced the opposite effects. We also found that BMP9 may not affect the chemokine (C-X-C motif) ligand 12 (CXCL12)/C-X-C chemokine receptor type 4 (CXCR4) axis to regulate the invasiveness and metastatic capacity of OS cells. Interestingly, CXCR4 was expressed in both 143B and MG63 cells, while CXCL12 was only detected in MG63 cells. Taken together, we hypothesize that BMP9 inhibits the migration and invasiveness of OS cells through a Smad-dependent pathway by downregulating the expression and activity of MMP9.

Some Geometric Constants Related to the Heights and Mid lines of Triangles in Banach Space

Dandan Du,Yuankang Fu,Zhijian Yang,Yongjin Li 경북대학교 자연과학대학 수학과 2023 Kyungpook mathematical journal Vol.63 No.1

In this paper, we introduce two new geometric constants related to the heights of triangles: ∆H(X) and ∆h(X, I). We also propose two new geometric constants, ∆m(X) and ∆M(X), related to the midlines of equilateral triangles, and discuss the relation between the heights and midlines in equilateral triangles. We give estimates for these geometric constants in terms of other geometric parameters, and the geometric constants are used to discuss geometric properties such as uniform non-squareness, uniform normal structure, and the fixed point property.

Granularity and Laxative Effect of Ultrafine Powder of Dendrobium officinale

DanDan Luo,Chao Qu,ZhenBiao Zhang,JianHui Xie,LieQiang Xu,HongMei Yang,CaiLan Li,GuoSheng Lin,HongFeng Wang,ZiRen Su 한국식품영양과학회 2017 Journal of medicinal food Vol.20 No.2

Constipation is a common disorder that is a significant source of morbidity among people around the world ranging from 2% to 28%. Dendrobium officinale Kimura et Migo is a traditional herbal medicine and health food used for tonicity of the stomach and promotion of body fluid production in China. This study aimed to prepare the ultrafine powder of Dendrobium officinale (UDO) and investigate its laxative effect and potential mechanism in mice with diphenoxylate-induced constipation. Results indicated that the mean diameter (d50) of UDO obtained by ball milling was 6.56 lm. UDO (62.5, 125, and 250 mg/kg, p.o.) could significantly enhance the gastrointestinal transit ratio and promote fecal output. Moreover, UDO treatment resulted in significant increases in the serum levels of acetylcholinesterase (AChE), gastrin (Gas), motilin (MTL), and substance P (SP), and obviously decreased serum contents of somatostatin (SS). Taken together, UDO, which can be easily obtained through milling to a satisfactory particle size, exhibited obvious laxative effect in diphenoxylate-induced constipated mice, and the mechanism might be associated with elevated levels of AChE, Gas, MTL, SP, and reduced production of SS. UDO has the potential for further development into an alternative effective diet therapy for constipation.

Coalescence of functional gold and monodisperse silver nanoparticles mediated by black <i>Panax ginseng</i> Meyer root extract

Wang, Dandan,Markus, Josua,Kim, Yeon-Ju,Wang, Chao,Jimé,nez Pé,rez, Zuly Elizabeth,Ahn, Sungeun,Aceituno, Veró,nica Castro,Mathiyalagan, Ramya,Yang, Deok Chun Dove Medical Press 2016 INTERNATIONAL JOURNAL OF NANOMEDICINE Vol.11 No.-

<P>A rapid biological synthesis of multifunctional gold nanoparticle (AuNp) and monodisperse silver nanoparticle (AgNp) was achieved by an aqueous extract of black <I>Panax ginseng</I> Meyer root. The physicochemical transformation into black ginseng (BG) greatly enhanced the pharmacological activities of white ginseng and its minor ginsenoside content. The optimal temperature conditions and kinetics of bioreduction were investigated. Formation of BG-AuNps and BG-AgNps was verified by ultraviolet–visible spectrophotometry at 548 and 412 nm, respectively. The biosynthesized BG-AgNps were spherical and monodisperse with narrow distribution, while BG-AuNps were icosahedral-shaped and moderately polydisperse. Synthesized nanoparticles exhibited long-term stability in buffers of pH 7.0–8.0 and biological media (5% bovine serum albumin) at an ambient temperature and at 37°C. BG-AgNps showed effective antibacterial activity against <I>Escherichia coli</I> and <I>Staphylococcus aureus</I>. BG-AuNps and BG-AgNps demonstrated increased scavenging activity against 2,2-diphenyl-1-picrylhydrazyl free radicals. In addition, BG-AuNps and BG-AgNps were nontoxic to HaCaT and MCF-7 cells; the latter showed no cytotoxicity at concentrations lower than 10 µg/mL. At higher concentrations, BG-AgNps exhibited apparent apoptotic activity in MCF-7 breast cancer cell line through reactive oxygen species generation and nuclear fragmentation.</P>

Tomato Yellow Leaf Curl China Virus Impairs Photosynthesis in the Infected Nicotiana benthamiana with βC1 as an Aggravating Factor

Tahir Farooq,Dandan Liu,Xueping Zhou,Qiuying Yang 한국식물병리학회 2019 Plant Pathology Journal Vol.35 No.5

Tomato yellow leaf curl China virus is a species of the widespread geminiviruses. The infection of Nicotiana benthamiana by Tomato yellow leaf curl China virus (TYLCCNV) causes a reduction in photosynthetic activity, which is part of the viral symptoms. βC1 is a viral factor encoded by the betasatellite DNA (DNAβ) accompanying TYLCCNV. It is a major viral pathogenicity factor of TYLCCNV. To elucidate the effect of βC1 on plants’ photosynthesis, we measured the relative chlorophyll (Chl) content and Chl fluorescence in TYLCCNV- infected and βC1 transgenic N. benthamiana plants. The results showed that Chl content is reduced in TYLCCNV A–infected, TYLCCNV A plus DNAβ (TYLCCNV A + β)–infected and βC1 transgenic plants. Further, changes in Chl fluorescence parameters, such as electron transport rate, Fv/Fm, NPQ, and qP, revealed that photosynthetic efficiency is compromised in the aforementioned N. benthamiana plants. The presense of βC1 aggravated the decrease of Chl content and photosynthetic efficiency during viral infection. Additionally, the real-time quantitative PCR analysis of oxygen evolving complex genes in photosystem II, such as PsbO, PsbP, PsbQ, and PsbR, showed a significant reduction of the relative expression of these genes at the late stage of TYLCCNV A + β infection and at the vegetative stage of βC1 transgenic N. benthamiana plants. In summary, this study revealed the pathogenicity of TYLCCNV in photosynthesis and disclosed the effect of βC1 in exacerbating the damage in photosynthesis efficiency by TYLCCNV infection.

Effects of Replacing Soy-oil with Soy-lecithin on Growth Performance, Nutrient Utilization and Serum Parameters of Broilers Fed Corn-based Diets

Huang, Jin,Yang, Dandan,Wang, Tian Asian Australasian Association of Animal Productio 2007 Animal Bioscience Vol.20 No.12

This study was conducted to examine the effects of different soy-oil and soy-lecithin levels on growth performance, nutrient utilization and serum parameters in broiler chickens. Two hundred and forty 1-day-old Arbor Acres chicks were randomly divided into 4 groups and treated as follows: basal diet with 2% soy-oil (SO); soy-oil and soy-lecithin mixture in proportion of 75/25 (SOL1), 50/50 (SOL2) and 2% lecithin (SL). At the end of the trial (42 d), birds in SOL1 group grew faster (p<0.05) and had better feed conversion efficiency (p<0.05) than other groups while SL group had the lowest performance (p<0.05). The utilization of ether extract was improved in SOL1 group (p<0.05) but apparent metabolizable energy (AME) and utilization of other nutrients decreased in SOL2 and SL group from 19 to 21 d. No significant effects were observed in apparent metabolizable energy, dry matter, crude protein and ether extract but the utilization of calcium and phosphorus was significantly improved in SL group (p<0.05) during 39 to 42 d. The birds fed with lecithin had lower serum total cholesterol and triglyceride than the control group (SO). Broilers fed with 2% lecithin (SL) had the highest insulin level (p<0.05). The results implied that soy-lecithin and soy-oil in a proportion of 25:75 had the highest growth performance and that soy-lecithin had cholesterol lowering capacity.

Probabilistic structural damage detection approaches based on structural dynamic response moments

Lei, Ying,Yang, Ning,Xia, Dandan Techno-Press 2017 Smart Structures and Systems, An International Jou Vol.20 No.2

Because of the inevitable uncertainties such as structural parameters, external excitations and measurement noises, the effects of uncertainties should be taken into consideration in structural damage detection. In this paper, two probabilistic structural damage detection approaches are proposed to account for the underlying uncertainties in structural parameters and external excitation. The first approach adopts the statistical moment-based structural damage detection (SMBDD) algorithm together with the sensitivity analysis of the damage vector to the uncertain parameters. The approach takes the advantage of the strength SMBDD, so it is robust to measurement noise. However, it requests the number of measured responses is not less than that of unknown structural parameters. To reduce the number of measurements requested by the SMBDD algorithm, another probabilistic structural damage detection approach is proposed. It is based on the integration of structural damage detection using temporal moments in each time segment of measured response time history with the sensitivity analysis of the damage vector to the uncertain parameters. In both approaches, probability distribution of damage vector is estimated from those of uncertain parameters based on stochastic finite element model updating and probabilistic propagation. By comparing the two probability distribution characteristics for the undamaged and damaged models, probability of damage existence and damage extent at structural element level can be detected. Some numerical examples are used to demonstrate the performances of the two proposed approaches, respectively.