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Conghui Liu,Yu Li,Hong Jiang,Yingchun Liu,Xiaomin Song 대한산부인과학회 2021 Obstetrics & Gynecology Science Vol.64 No.3
ObjectiveTo compare the clinical outcomes of fresh embryo transfers (ETs) and frozen-thawed embryo transfers (FETs) after afreeze-all cycle in women ≥40 years old with poor ovarian response (POR). MethodsWe performed a single-center, retrospective, case-control study of patients who underwent in vitro fertilizationbetween January 2014 and June 2019. We included a total of 192 patients aged 40 years or older from whom 3 orfewer oocytes had been retrieved and who were receiving cleavage-stage ET in this study. Of these patients, 101 and91 patients underwent fresh ET and FET, respectively. The primary outcome was the live birth rate (LBR) after thefirst ET. Logistic regression analysis was used to compare the IVF outcomes and neonatal characteristics between thefresh ET and FET groups, adjusting for maternal age, body mass index, luteinizing hormone, and the number of goodquality embryos transferred. ResultsThe mean maternal ages and number of oocytes retrieved (43.2 years and 2.3 in both groups, P=0.902 and P=0.927,respectively) were similar in the fresh ET and FET groups. No significant difference was observed between the LBRsof the fresh ET and FET groups (adjusted odds ratio, 1.28; 95% confidence interval, 0.29–5.70). The clinical pregnancyand miscarriage rates, and neonatal characteristics (birth weights and premature infant rates) were similar betweenthe 2 groups. ConclusionsFET after the freeze-all strategy had no beneficial impact on the clinical outcomes of women ≥40 years with POR.
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Multi‑DoF wireless power transfer systems based on magnetic dipole coils with multiple receivers
Xiaobo Liu,Cancan Rong,Xiong Tao,Conghui Lu,Yingyin Zeng,Renzhe Liu,Minghai Liu 전력전자학회 2022 JOURNAL OF POWER ELECTRONICS Vol.22 No.3
To improve the degree of freedom (DoF), and the multi-terminal power supply capability of wireless power transfer (WPT) systems, multi-DoF WPT systems for multiple pickups based on magnetic dipole coils are proposed in this paper, which can simultaneously charge multiple receivers regardless of the position degree. First, the equivalent circuit model of the magnetic dipole coils is provided. The critical factors of the proposed multi-load systems are analyzed, such as transfer efficiency, power distribution, and optimal load. Second, a multi-load wireless power transfer system with equal transmitting (TX) and receiving (RX) coil is designed, and the misalignment tolerance of lateral and rotating occasions for the RX coils is discussed. In particular, a multi-load WPT system with miniaturized step-laminated receivers is implemented based on the magnetic dipole coils. Finally, experimental prototypes are established. The obtained results indicate that the output power for the equal dual-load WPT system can reach more than 78 W with a total efficiency of more than 80% under a transfer distance of length of the receiving coil winding. In addition, the output power of the non-equal four-load WPT system can reach 30 W with a total efficiency of 86%. The proposed systems provide practical guidance for the future development of multi-DoF WPT systems for use in portable devices, unmanned intelligent systems, and smart household applications.
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Guojun Liu,Fang He,Yan Li,Xinbo Li,Hong Zhao,Conghui Wang,Conghong Zhan,Chunxiu Tang 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.8
Based on the liquid-phase reduction mechanism, a controllable synthesis method, which uses piezoelectric-actuated high-frequency vibration self-circulating microfluidic reactor, to prepare silver nanoparticles is proposed. Firstly, the synthesis mechanism of silver nanoparticles and the working principle of the microfluidic reactor were analyzed. Then, in order to study and explore the influence of self-circulating and high frequency vibration on the synthesis of silver nanoparticles, a series of related synthesis experiments were carried out. The synthesized silver nanoparticles were characterized by UV-Visible spectroscopy and transmission electron microscopy. The effects of micropump driving voltage and high-frequency vibration on the synthesis of silver nanoparticles were analyzed. The experiment results show that when the silver nanoparticles were synthesized using piezoelectric-actuated high-frequency vibration self-circulating microfluidic reactor, the higher the driving voltage of the circulating reflux micropump, the faster the vortex rotation speed in the mixing pool and the more uniform the reagent reaction. Besides, high-frequency vibration can suppress the aggregation of silver nanoparticles, and balance the growth environment of particles, which is beneficial to the formation of silver nanoparticles with good monodispersity, high sphericity and small size deviation.
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Yufeng Qi,Haodong Wu,Conghui Liu,Danni Zheng,Congzhi Yan,Wenjing Hu,Xiaohua Zhang,Xuanxuan Dai 한국유방암학회 2022 Journal of breast cancer Vol.25 No.4
Purpose: The incidence rate of breast cancer (BC) has increased annually. Downstream neighbor of son (DONSON) critically affects cell cycle progression and maintains stable genomic properties; however, its relevant effects on BC growth and progression require in-depth investigation. Methods: DONSON upregulation was validated in public databases. DONSON expression in matched BC and adjacent tissues and cell lines (MDA-MB-231, BT-549, and HS-578T) was determined using quantitative reverse transcription polymerase chain reaction. In vitro apoptosis, invasion, migration, and proliferation tests were performed to ascertain the functions of DONSON in BC cell lines. Then, using western blot analysis, the levels of DONSON downstream proteins were determined. Results: Compared to the control, DONSON was expressed at higher levels in BC tissues and cell lines. DONSON knockdown facilitated apoptosis and limited proliferation, migration, invasion, and S/G2 transition of BC cells in vitro. Furthermore, DONSON overexpression promoted BC cell proliferation and inhibited apoptosis in vitro. Moreover, DONSON knockdown reduced cyclin A1 and cyclin-dependent kinase 2 levels. Moreover, DONSON knockdown limited the progression of epithelial-mesenchymal transition. Conclusion: DONSON critically affects BC growth and serves as a possible target and marker for the efficacy of subsequent therapies.
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